The origin of high-resolution IETS-STM images of organic molecules with functionalized tips

Recently, the family of high-resolution scanning probe imaging techniques using decorated tips has been complimented by a method based on inelastic electron tunneling spectroscopy (IETS). The new technique resolves the inner structure of organic molecules by mapping the vibrational energy of a single carbonmonoxide (CO) molecule positioned at the apex of a scanning tunnelling microscope (STM) tip. Here, we explain high-resolution IETS imaging by extending the model developed earlier for STM and atomic force microscopy (AFM) imaging with decorated tips. In particular, we show that the tip decorated with CO acts as a nanoscale sensor that changes the energy of the CO frustrated translation in response to the change of the local curvature of the surface potential. In addition, we show that high resolution AFM, STM and IETS-STM images can deliver information about intramolecular charge transfer for molecules deposited on a~surface. To demonstrate this, we extended our numerical model by taking into the account the electrostatic force acting between the decorated tip and surface Hartree potential.Comment: 5 pages, 4 figure

Secondary Science with ROTSE Data

The ROTSE optical GRB follow‐up instrument offers an excellent possibility for a secondary science with the data obtained within the sky monitoring. We present and discuss the results of a project of analysing two selected ROTSE monitoring fields with the goal to study the long‐term behaviour of the objects located inside. The method developed and tested can be applied in a general way to study light changes of astrophysical objects of various types within the limiting magnitude of the ROTSE device. © 2003 American Institute of PhysicsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87935/2/544_1.pd

A new multi-center approach to the exchange-correlation interactions in ab initio tight-binding methods

A new approximate method to calculate exchange-correlation contributions in the framework of first-principles tight-binding molecular dynamics methods has been developed. In the proposed scheme on-site (off-site) exchange-correlation matrix elements are expressed as a one-center (two-center) term plus a {\it correction} due to the rest of the atoms. The one-center (two-center) term is evaluated directly, while the {\it correction} is calculated using a variation of the Sankey-Niklewski \cite{Sankey89} approach generalized for arbitrary atomic-like basis sets. The proposed scheme for exchange-correlation part permits the accurate and computationally efficient calculation of corresponding tight-binding matrices and atomic forces for complex systems. We calculate bulk properties of selected transition (W,Pd), noble (Au) or simple (Al) metals, a semiconductor (Si) and the transition metal oxide Ti$O_2$ with the new method to demonstrate its flexibility and good accuracy.Comment: 17 pages, 5 figure

Metastatic MHC class I-negative mouse cells derived by transformation with human papillomavirus type 16

In the endeavour to develop a model for studying gene therapy of cancers associated with human papillomaviruses (HPVs), mouse cells were transformed with the HPV type 16 (HPV16) and activated H-ras oncogenes. This was done by contransfection of plasmid p16HHMo, carrying the HPV16 E6/E7 oncogenes, and plasmid pEJ6.6, carrying the gene coding for human H-ras oncoprotein activated by G12V mutation, into secondary C57BL/6 mouse kidney cells. An oncogenic cell line, designated MK16/1/IIIABC, was derived. The epithelial origin of the cells was confirmed by their expression of cytokeratins. No MHC class I and class II molecules were detected on the surface of MK16/1/IIIABC cells. Spontaneous metastases were observed in lymphatic nodes and lungs after prolonged growth of MK16/1/IIIABC-induced subcutaneous tumours. Lethally irradiated MK16/1/IIIABC cells induced protection against challenge with 105homologous cells, but not against a higher cell dose (5 × 105). Plasmids p16HHMo and pEJ6.6 were also used for preventive immunization of mice. In comparison with a control group injected with pBR322, they exhibited moderate protection, in terms of prolonged survival, against MK16/1/IIIABC challenge (P< 0.03). These data suggest that MK16/1/IIIABC cells may serve as a model for studying immune reactions against HPV16-associated human tumours. © 2001 Cancer Research Campaign http://www.bjcancer.co

A multiwavelength study of Swift GRB 060111B constraining the origin of its prompt optical emission

In this work, we present the results obtained from a multi-wavelength campaign, as well as from the public Swift/BAT, XRT, and UVOT data of GRB 060111B for which a bright optical emission was measured with good temporal resolution during the prompt phase. We identified the host galaxy at R~25 mag; its featureless spectral continuum and brightness, as well as the non-detection of any associated supernova 16 days after the trigger and other independent redshift estimates, converge to z~1-2. From the analysis of the early afterglow SED, we find that non-negligible host galaxy dust extinction, in addition to the Galactic one, affects the observed flux in the optical regime. The extinction-corrected optical-to-gamma-ray spectral energy distribution during the prompt emission shows a flux density ratio $F_{\gamma}/F_{opt}$=0.01-0.0001 with spectral index $\beta_{\gamma,opt}> \beta_{\gamma}$, strongly suggesting a separate origin of the optical and gamma-ray components. This result is supported by the lack of correlated behavior in the prompt emission light curves observed in the two energy domains. The properties of the prompt optical emission observed during GRB 060111B favor interpretation of this optical light as radiation from the reverse shock in a thick shell limit and in the slow cooling regime. The expected peak flux is consistent with the observed one corrected for the host extinction, likely indicating that the starting time of the TAROT observations is very near to or coincident with the peak time. The estimated fireball initial Lorentz factor is >260-360 at z=1-2, similar to the Lorentz factors obtained from other GRBs. GRB 060111B is a rare, good test case of the reverse shock emission mechanism in both the X-ray and optical energy ranges.Comment: Accepted for publication in Astronomy and Astrophysics, 15 pages,10 figures and 7 table

New developments in aerosol measurements using stellar photometry

The idea of using stellar photometry for atmospheric monitoring for optical experiments in highenergy astrophysics is seemingly straightforward, but reaching high precision of the order of 0.01 in the determination of the vertical aerosol optical depth (VAOD) has proven difficult. Wide-field photometry over a large span of altitudes allows a fast determination of VAOD independently of the absolute calibration of the system, while providing this calibration as a useful by-product. Using several years of data taken by the FRAM (F/(Ph)otometric Robotic Atmospheric Monitor) telescope at the Pierre Auger Observatory in Argentina and about a year of data taken by a similar instrument deployed at the planned future Southern site of the Cherenkov Telescope Array in Chile, we have developed methods to improve the precision of this measurement technique towards and possibly beyond the 0.01 mark. Detailed laboratory measurements of the response of the whole system to both the spectrum and intensity of incoming light have proven indispensable in this analysis as the usual assumption of linearity of the CCD detectors is not valid anymore for the conditions of the observations

The dark nature of GRB 051022 and its host galaxy

We present multiwavelength (X-ray/optical/near-infrared/millimetre) observations of GRB 051022 between 2.5 hours and ~1.15 yr after the event. It is the most intense gamma-ray burst (~ 10^-4 erg cm^-2) detected by HETE-2, with the exception of the nearby GRB 030329. Optical and near infrared observations did not detect the afterglow despite a strong afterglow at X-ray wavelengths. Millimetre observations at Plateau de Bure (PdB) detected a source and a flare, confirming the association of this event with a moderately bright (R = 21.5) galaxy. Spectroscopic observations of this galaxy show strong [O II], Hbeta and [O III] emission lines at a redshift of 0.809. The spectral energy distribution of the galaxy implies Av (rest frame) = 1.0 and a starburst occuring ~ 25 Myr ago, during which the star-forming-rate reached >= 25 Msun/yr. In conjunction with the spatial extent (~ 1'') it suggests a very luminous (Mv = - 21.8) blue compact galaxy, for which we also find with Z Zsun. The X-ray spectrum shows evidence of considerable absorption by neutral gas with NH, X-ray = 3.47(+0.48/-0.47) x 10^22 cm^-2 (rest frame). Absorption by dust in the host galaxy at z = 0.809 certainly cannot account for the non-detection of the optical afterglow, unless the dust-to-gas ratio is quite different than that seen in our Galaxy (i.e. large dust grains). It is likely that the afterglow of the dark GRB 051022 was extinguished along the line of sight by an obscured, dense star forming region in a molecular cloud within the parent host galaxy. This galaxy is different from most GRB hosts being brighter than L* by a factor of 3. We have also derived a SFR ~ 50 Msun/yr and predict that this host galaxy will be detected at sub-mm wavelengths.Comment: 7 Pages, 7 figures. Accepted in Astronomy and Astrophysic