MeerTRAP: Twelve Galactic fast transients detected in a real-time, commensal MeerKAT survey

MeerTRAP is a real-time untargeted search project using the MeerKAT telescope to find single pulses from fast radio transients and pulsars. It is performed commensally with the MeerKAT large survey projects (LSPs), using data from up to 64 of MeerKAT's 13.96~m dishes to form hundreds of coherent beams on sky, each of which is processed in real time to search for millisecond-duration pulses. We present the first twelve Galactic sources discovered by MeerTRAP, with DMs in the range of 33--381~pc~cm$^{-3}$. One source may be Galactic or extragalactic depending on the Galactic electron density model assumed. Follow-up observations performed with the MeerKAT, Lovell, and Parkes radio telescopes have detected repeat pulses from seven of the twelve sources. Pulse periods have been determined for four sources. Another four sources could be localised to the arcsecond-level using a novel implementation of the tied-array beam localisation method.Comment: 16 pages, 14 figure

Probing the extragalactic fast transient sky at minute timescales with DECam

Searches for optical transients are usually performed with a cadence of days to weeks, optimised for supernova discovery. The optical fast transient sky is still largely unexplored, with only a few surveys to date having placed meaningful constraints on the detection of extragalactic transients evolving at sub-hour timescales. Here, we present the results of deep searches for dim, minute-timescale extragalactic fast transients using the Dark Energy Camera, a core facility of our all-wavelength and all-messenger Deeper, Wider, Faster programme. We used continuous 20s exposures to systematically probe timescales down to 1.17 minutes at magnitude limits $g > 23$ (AB), detecting hundreds of transient and variable sources. Nine candidates passed our strict criteria on duration and non-stellarity, all of which could be classified as flare stars based on deep multi-band imaging. Searches for fast radio burst and gamma-ray counterparts during simultaneous multi-facility observations yielded no counterparts to the optical transients. Also, no long-term variability was detected with pre-imaging and follow-up observations using the SkyMapper optical telescope. We place upper limits for minute-timescale fast optical transient rates for a range of depths and timescales. Finally, we demonstrate that optical $g$-band light curve behaviour alone cannot discriminate between confirmed extragalactic fast transients such as prompt GRB flashes and Galactic stellar flares.Comment: Published in MNRA

Detection of a glitch in the pulsar J1709-4429

We report the detection of a glitch event in the pulsar J1709$-$4429 (also known as B1706$-$44) during regular monitoring observations with the Molonglo Observatory Synthesis Telescope (UTMOST). The glitch was found during timing operations, in which we regularly observe over 400 pulsars with up to daily cadence, while commensally searching for Rotating Radio Transients, pulsars, and FRBs. With a fractional size of $\Delta\nu/\nu \approx 52.4 \times10^{-9}$, the glitch reported here is by far the smallest known for this pulsar, attesting to the efficacy of glitch searches with high cadence using UTMOST.Comment: 3 pages, 1 figur

The UTMOST pulsar timing programme II:Timing noise across the pulsar population

While pulsars possess exceptional rotational stability, large scale timing studies have revealed at least two distinct types of irregularities in their rotation: red timing noise and glitches. Using modern Bayesian techniques, we investigated the timing noise properties of 300 bright southern-sky radio pulsars that have been observed over 1.0-4.8 years by the upgraded Molonglo Observatory Synthesis Telescope (MOST). We reanalysed the spin and spin-down changes associated with nine previously reported pulsar glitches, report the discovery of three new glitches and four unusual glitch-like events in the rotational evolution of PSR J1825$-$0935. We develop a refined Bayesian framework for determining how red noise strength scales with pulsar spin frequency ($\nu$) and spin-down frequency ($\dot{\nu}$), which we apply to a sample of 280 non-recycled pulsars. With this new method and a simple power-law scaling relation, we show that red noise strength scales across the non-recycled pulsar population as $\nu^{a} |\dot{\nu}|^{b}$, where $a = -0.84^{+0.47}_{-0.49}$ and $b = 0.97^{+0.16}_{-0.19}$. This method can be easily adapted to utilise more complex, astrophysically motivated red noise models. Lastly, we highlight our timing of the double neutron star PSR J0737$-$3039, and the rediscovery of a bright radio pulsar originally found during the first Molonglo pulsar surveys with an incorrectly catalogued position.Comment: Accepted by MNRAS. 28 pages, 8 figures, 8 table

Frb 20210405i:a nearby Fast Radio Burst localised to sub-arcsecond precision with MeerKAT

We present the first sub-arcsecond localised Fast Radio Burst (FRB) detected using MeerKAT. FRB 20210405I was detected in the incoherent beam using the MeerTRAP pipeline on 2021 April 05 with a signal to noise ratio of 140.8 and a dispersion measure of 565.17 pc cm$^{-3}$. It was detected while MeerTRAP was observing commensally with the ThunderKAT large survey project, and was sufficiently bright that we could use the ThunderKAT 8s images to localise the FRB. Two different models of the dispersion measure in the Milky Way and halo suggest that the source is either right at the edge of the Galaxy, or outside. This highlights the uncertainty in the Milky Way dispersion measure models, particularly in the Galactic Plane, and the uncertainty of Milky Way halo models. Further investigation and modelling of these uncertainties will be facilitated by future detections and localisations of nearby FRBs. We use the combined localisation, dispersion measure, scattering, specific luminosity and chance coincidence probability information to find that the origin is most likely extra-galactic and identify the likely host galaxy of the FRB: 2MASS J1701249$-$4932475. Using SALT spectroscopy and archival observations of the field, we find that the host is a disk/spiral galaxy at a redshift of $z=0.066$

FRB 20210405I: a nearby Fast Radio Burst localised to sub-arcsecond precision with MeerKAT

We present the first sub-arcsecond localised Fast Radio Burst (FRB) detected using MeerKAT. FRB 20210405I was detected in the incoherent beam using the MeerTRAP pipeline on 2021 April 05 with a signal to noise ratio of 140.8 and a dispersion measure of 565.17 pc cm$^{-3}$. It was detected while MeerTRAP was observing commensally with the ThunderKAT large survey project, and was sufficiently bright that we could use the ThunderKAT 8s images to localise the FRB. Two different models of the dispersion measure in the Milky Way and halo suggest that the source is either right at the edge of the Galaxy, or outside. This highlights the uncertainty in the Milky Way dispersion measure models, particularly in the Galactic Plane, and the uncertainty of Milky Way halo models. Further investigation and modelling of these uncertainties will be facilitated by future detections and localisations of nearby FRBs. We use the combined localisation, dispersion measure, scattering, specific luminosity and chance coincidence probability information to find that the origin is most likely extra-galactic and identify the likely host galaxy of the FRB: 2MASS J1701249$-$4932475. Using SALT spectroscopy and archival observations of the field, we find that the host is a disk/spiral galaxy at a redshift of $z=0.066$.Comment: 15 pages, 4 tables, 10 figures. Accepted to MNRA

The Third Fermi Large Area Telescope Catalog of Gamma-ray Pulsars

We present 294 pulsars found in GeV data from the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope. Another 33 millisecond pulsars (MSPs) discovered in deep radio searches of LAT sources will likely reveal pulsations once phase-connected rotation ephemerides are achieved. A further dozen optical and/or X-ray binary systems co-located with LAT sources also likely harbor gamma-ray MSPs. This catalog thus reports roughly 340 gamma-ray pulsars and candidates, 10% of all known pulsars, compared to $\leq 11$ known before Fermi. Half of the gamma-ray pulsars are young. Of these, the half that are undetected in radio have a broader Galactic latitude distribution than the young radio-loud pulsars. The others are MSPs, with 6 undetected in radio. Overall, >235 are bright enough above 50 MeV to fit the pulse profile, the energy spectrum, or both. For the common two-peaked profiles, the gamma-ray peak closest to the magnetic pole crossing generally has a softer spectrum. The spectral energy distributions tend to narrow as the spindown power $\dot E$ decreases to its observed minimum near $10^{33}$ erg s$^{-1}$, approaching the shape for synchrotron radiation from monoenergetic electrons. We calculate gamma-ray luminosities when distances are available. Our all-sky gamma-ray sensitivity map is useful for population syntheses. The electronic catalog version provides gamma-ray pulsar ephemerides, properties and fit results to guide and be compared with modeling results.Comment: 142 pages. Accepted by the Astrophysical Journal Supplemen

Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

Aims The objective of the Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) was to determine whether aliskiren, a direct renin inhibitor, would improve post-discharge outcomes in patients with hospitalization for heart failure (HHF) with reduced ejection fraction. Pre-specified subgroup analyses suggested potential heterogeneity in post-discharge outcomes with aliskiren in patients with and without baseline diabetes mellitus (DM). Methods and results ASTRONAUT included 953 patients without DM (aliskiren 489; placebo 464) and 662 patients with DM (aliskiren 319; placebo 343) (as reported by study investigators). Study endpoints included the first occurrence of cardiovascular death or HHF within 6 and 12 months, all-cause death within 6 and 12 months, and change from baseline in N-terminal pro-B-type natriuretic peptide (NT-proBNP) at 1, 6, and 12 months. Data regarding risk of hyperkalaemia, renal impairment, and hypotension, and changes in additional serum biomarkers were collected. The effect of aliskiren on cardiovascular death or HHF within 6 months (primary endpoint) did not significantly differ by baseline DM status (P = 0.08 for interaction), but reached statistical significance at 12 months (non-DM: HR: 0.80, 95% CI: 0.64-0.99; DM: HR: 1.16, 95% CI: 0.91-1.47; P = 0.03 for interaction). Risk of 12-month all-cause death with aliskiren significantly differed by the presence of baseline DM (non-DM: HR: 0.69, 95% CI: 0.50-0.94; DM: HR: 1.64, 95% CI: 1.15-2.33; P < 0.01 for interaction). Among non-diabetics, aliskiren significantly reduced NT-proBNP through 6 months and plasma troponin I and aldosterone through 12 months, as compared to placebo. Among diabetic patients, aliskiren reduced plasma troponin I and aldosterone relative to placebo through 1 month only. There was a trend towards differing risk of post-baseline potassium ≥6 mmol/L with aliskiren by underlying DM status (non-DM: HR: 1.17, 95% CI: 0.71-1.93; DM: HR: 2.39, 95% CI: 1.30-4.42; P = 0.07 for interaction). Conclusion This pre-specified subgroup analysis from the ASTRONAUT trial generates the hypothesis that the addition of aliskiren to standard HHF therapy in non-diabetic patients is generally well-tolerated and improves post-discharge outcomes and biomarker profiles. In contrast, diabetic patients receiving aliskiren appear to have worse post-discharge outcomes. Future prospective investigations are needed to confirm potential benefits of renin inhibition in a large cohort of HHF patients without D

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc

Old made new again

This image originally appeared in the 2015 Research student photography and image competition held to celebrate National Science Week (Aug 15-23). Blurb: This photo shows the bottom part of the Molonglo radio telescope near Canberra. It is the largest steerable telescope in the Southern hemisphere and will turn 50 years old later this year. The red part is one of the main gears that are responsible for the North-South movement of the telescope. I am helping refurbish it in order to observe pulsars, which are rapidly rotating and highly magnetized neutron stars in order to understand their structure and the properties of ultra-dense matter through the monitoring of glitches in their otherwise very stable rotation. It will also help us determine the origin of the mysterious fast radio bursts