Prosthetic Knee for CURE Kenya: Design and Manufacturing

The Prosthetic Knee team is partnered with the CURE International Hospital in Kijabe, Kenya. In the region surrounding our client’s facility, there is a large number of lower-extremity amputations due to various infections and diseases. Often, these patients choose to undergo a more invasive transfemoral amputation to enable them to use a less expensive above-knee prosthesis. The goal of the project is to present the orthopedic workshop at CURE with a manufacturable prosthetic knee design in May of 2023 that provides through-knee amputee patients with a more affordable, aesthetically pleasing, and lightweight prosthetic option, thereby removing the need to undergo an additional amputation above the knee. The poster presents the overarching elements of the prosthetic design in addition to the recently integrated locking and damping components, which aid in the functionality of the knee. Funding for this work provided by The Collaboratory for Strategic Partnerships and Applied Research.https://mosaic.messiah.edu/engr2022/1013/thumbnail.jp

Prosthetic Knee for CURE Kenya

Lower limb amputations are common in sub-Saharan Africa due to the prevalence of disease and infection in communities that lack access to adequate healthcare. Our project, Prosthetic Knee, partners with the CURE International Hospital in Kijabe, Kenya. In the region surrounding our client’s facility, there is a large number of lower-extremity amputations due to various infections and diseases. While many of these amputees only require a through-knee amputation, the lack of an affordable through-knee prosthesis often forces patients to undergo a more invasive transfemoral amputation to enable them to use a cheaper above-knee prosthesis. The goal of our project is to design and manufacture a financially accessible and user-friendly prosthetic knee for knee-disarticulation patients that can be manufactured in Messiah University’s machine shop (and ultimately, at the orthopedic facility in Kijabe). This year, the team’s work has included finalizing the prototype design, conducting finite element analysis in SOLIDWORKS to evaluate the knee’s static and fatigue strength, and beginning the process of physical manufacturing. Additionally, a damping mechanism driven by a spring-loaded system has been developed and integrated into the design after completing motion analysis and SOLIDWORKS modeling. Our future goals include manufacturing a complete metal prototype of the knee, conducting physical strength and fatigue testing on the metal prototype, and continuing iterative prototyping of the damper in preparation for physical implementation.https://mosaic.messiah.edu/engr2021/1014/thumbnail.jp

The Grizzly, October 13, 1998

Drunk Driving Hits the Campus • A Tale of Two Teams • Wismer Lower Library? • As the World Communicates • Friday Night Fights • GALA Makes Changes, Seeks Broader Support • Wellness to Promote Alcohol Awareness • Berman Quilt Exhibit • Sculptures on Campus • Field Hockey Falls to 0-11 • Women\u27s Soccer at .500 • Football Downed at Homecoming • Cross Country Competes in Dickinson Invitational • UC Volleyball Keeps Steady Pace • Faculty Coaches Give New Edge on Footballhttps://digitalcommons.ursinus.edu/grizzlynews/1426/thumbnail.jp

The Grizzly, October 27, 1998

Mischief and Mayhem Night • Big Brother\u27s in the Library • Rewind: Homecoming Alterations • Racism: One Piece of the Puzzle • The Democratic Dilemma of Legislating Hate • Are We Creatures of Habit? • A Look at What Ursinus Terms as Security • Students Voice Security Concerns • Borsdorf Spreads Fitness Message Over East Coast • Sculpture Depicts Trauma, Unity and Sacrifice of War Years • Ursinus Welcomes Savadove • Jeffrey Gaines Entertains Ursinus • Church on Film • McKellen Teaches Us a Thing or Two in Apt Pupil • The Big Fella\u27s Forum • Ursinus Destroys Gettysburg • Linebacker Vecchio Shines for Ursinus • Women\u27s Soccer Makes History • Cross Country Runs Over Competition • Soccer Falls Against Gettysburg • UC Volleyball Evens Out at .500 • Field Hockey Chalks Up First Victoryhttps://digitalcommons.ursinus.edu/grizzlynews/1991/thumbnail.jp

The Grizzly, November 10, 1998

Financial Aid: Who Here Gets It? • President Pleased with Success of Roundtable • Upperclassman Mentors • Opinion: Letter to the Editor; New Athletic Facility; Reflection on Mid-term Elections; U.S. Policy Makers, Look Before you Leap; Cashing in on the Past • Betting, Off-Track and On-Campus • Kidnapped? Grizzly Uncovers Surprising Truth About Missing Corson Statue • War Years Classes Dedicate Promise-Anthem • Remembering War Years Life at Ursinus • Eden Cinema at Ursinus • Waiting for the World to Catch Up • Swimming Takes First Plunge • UC Field Hockey Finishes Strong • Bears\u27 Future: Contenders or Pretenders? • NCAA Sets to Control Wrestling Tragedies • Men\u27s Basketball Prepares for Tough Schedule • Ursinus Athletes Honored • UC Soccer Finishes Season with Tough Losshttps://digitalcommons.ursinus.edu/grizzlynews/1428/thumbnail.jp

Developing asymmetric iron and ruthenium-based cyclone complexes : complex factors influence the asymmetric induction in the transfer hydrogenation of ketones

The preparation of a range of asymmetric iron and ruthenium-cyclone complexes, and their application to the asymmetric reduction of a ketone, are described. The enantioselectivity of ketone reduction is influenced by a single chiral centre in the catalyst, as well as by the planar chirality in the catalyst. This represents the first example of asymmetric ketone reduction using an iron cyclone catalyst

A digital intervention addressing alcohol use problems (the “DayBreak” program): Quasi-experimental randomized controlled trial

©Robert J Tait, Raquel Paz Castro, Jessica Jane Louise Kirkman, Jamie Christopher Moore, Michael P Schaub. Background: Alcohol use is prevalent in many societies and has major adverse impacts on health, but the availability of effective interventions limits treatment options for those who want assistance in changing their patterns of alcohol use. Objective: This study evaluated the new Daybreak program, which is accessible via mobile app and desktop and was developed by Hello Sunday Morning to support high-risk drinking individuals looking to change their relationship with alcohol. In particular, we compared the effect of adding online coaching via real-time chat messages (intervention group) to an otherwise self-guided program (control group). Methods: We designed the intervention as a randomized control trial, but as some people (n=48; 11.9%) in the control group were able to use the online coaching, the main analysis comprised all participants. We collected online surveys at one-month and three-months follow-up. The primary outcome was change in alcohol risk (measured with the alcohol use disorders identification test–consumption [AUDIT–C] score), but other outcomes included the number of standard drinks per week, alcohol-related days out of role, psychological distress (Kessler-10), and quality of life (EUROHIS-QOL). Markers of engagement with the program included posts to the site and comments on the posts of others. The primary analysis used Weighted Generalized Estimating Equations. Results: We recruited 398 people to the intervention group (50.2%) and 395 people to the control group (49.8%). Most were female (71%) and the mean age was 40.1 years. Most participants were classified as probably dependent (550, 69%) on the AUDIT–10, with 243 (31%) classified with hazardous or harmful consumption. We followed up with 334 (42.1%) participants at one month and 293 (36.9%) at three months. By three months there were significant improvements in AUDIT–C scores (down from mean 9.1 [SD 1.9] to 5.8 [SD 3.1]), alcohol consumed per week (down from mean 37.1 [SD 28.3] to mean 17.5 [SD 18.9]), days out of role (down from mean 1.6 [SD 3.6] to 0.5 [SD 1.6]), quality of life (up from 3.2 [SD 0.7] to 3.6 [SD 0.7]) and reduced distress (down from 24.8 [SD 7.0] to 19.0 [SD 6.6]). Accessing online coaching was not associated with improved outcomes, but engagement with the program (eg, posts and comments on the posts of others) were significantly associated with improvements (eg, in AUDIT–C, alcohol use and EUROHIS-QOL). Reduced alcohol use was found for both probably dependent (estimated marginal mean of 40.8 to 20.1 drinks) and hazardous or harmful alcohol users (estimated marginal mean of 22.9 to 11.9 drinks). Conclusions: Clinically significant reductions in alcohol use were found, as well as reduced alcohol risk (AUDIT–C) and days out of role. Importantly, improved alcohol-related outcomes were found for both hazardous or harmful and probably dependent drinkers. Since October 2016, Daybreak has reached more than 50,000 participants. Therefore, there is the potential for the program to have an impact on alcohol-related problems at a population health level, importantly including an effect on probably dependent drinkers