The Fight to End Human/Sex Trafficking

This paper will examine what human trafficking and sex trafficking is and how it has evolved over the years. The National Human Trafficking Resource Center (NHTRC) at the Polaris Project has statistical information that indicates that in 2019, Ohio has been as high as fifth in the standing amid all states in over-all reported cases involving human trafficking. The methods that will be used during this project are a baseline and exit survey, education, and scenario-based trainings. The Theory of Goal Attainment is the theoretical framework used in this project. The major assumptions of this theory include the focus of nursing is the care of the human being (patient). This theory is relevant to human/sex trafficking in the way of the nurse/health care staff building relationships to help restore victims back to functioning human beings. The purpose of this project is to provide awareness to the community of what human trafficking and sex trafficking can look like and educate medical staff and the community on how to disrupt and prevent human/sex trafficking. The findings of this project will also propose the increase in criminal sentencing for convicted individuals involved and associated with human/sex trafficking

Estudio de CD 61, CD163 e ICAM-1 en la fisiopatología de aterotrombosis y efecto de la piel de manzana en la expresión de ICAM-1, en modelos animales

58 p.Las enfermedades cardiovasculares son la principal causa de muerte a nivel mundial, entre ellas las de tipo isquémicas son las más prevalentes, y en las cuales el desarrollo de placas ateroscleróticas es el proceso fisiopatológico central. El estudio de la aterosclerosis es fundamental para comprender como se inicia este proceso y los factores que influyen en su desarrollo. Distintas metodologías de laboratorio, como modelos animales de aterotrombosis e inmunohistoquímica, permiten reconocer células y moléculas que participan en el proceso ateromatoso las que van interactuando según la progresión de la lesión, entre ellas las plaquetas, monocito/macrófagos y moléculas de adhesión tal como ICAM-1. En este trabajo se realizó inmunohistoquímica para CD61, CD163 e ICAM-1 y se estudió su expresión en tres estadios del proceso ateromatoso, una etapa inicial representada por ratones CF-1 alimentados con dieta grasa, etapa avanzada obtenida con ratones ApoE- KO alimentados con dieta grasa y una etapa final de trombosis, realizada con FeCl3 en conejos neozelandeses. También se evaluó el efecto del suplemento de piel de manzana en una dieta rica en grasa sobre la expresión de ICAM-1, en ratones ApoE- KO. En los cortes de la etapa inicial se observó expresión endotelial para CD61, ICAM-1 y CD163, reflejado como una leve positividad para estos marcadores. En la etapa avanzada se observó gran positividad para el inmunomarcaje de las moléculas antes mencionadas a nivel endotelial como en el interior de la lesión ateromatosa. En la etapa de trombosis, los cortes mostraron positividad para los tres marcadores. Al estudiar, el efecto del suplemento de piel de manzana en la dieta grasa administrada a ratones ApoE- KO, se observó leve positividad para el inmunomarcaje de ICAM-1. Estos resultados demuestran la participación de las plaquetas en todo el proceso aterotrombótico, desde la disfunción endotelial hasta la etapa final de trombosis, en estrecha relación con monocito/macrófagos, esta interacción aumenta mientras avanza la enfermedad, principalmente en sitios donde existen núcleos lipídicos. Con respecto al efecto de la piel de manzana enla dieta ésta mostró una detención en la progresión de la enfermedad ateromatosa, observada como una disminución del tamaño de la placa, y una menor expresión de ICAM-1, comparado con los ratones alimentados solo con dieta grasa

INTO Connect Updates

INTO Connect is a software platform that provides faculty and administrators with the opportunity to maintain student records in a secure online environment that meets the privacy policies of the institution and the privacy laws of the federal government. This session introduces the platform to possible new users and highlights the benefits and challenges of using INTO Connect for Academic English programs. The session also explores the possibilities of how INTO Connect can be used to meet the needs of different institutions. In this session, attendees will learn: 1. The benefits and challenges of integrating INTO Connect with your existing program: A. Faculty buy-in B. Faculty training C. Functional use of INTO Connect (Attendance, Reports and etc). D. Program administration E. Meeting FERPA standards and institutional standards F. Costs of setup and maintenance G. Future uses of the platform 2. Meet the needs of different institutions A. What is currently available on INTO Connect for use B. What can be made available on INTO Connect for use 3. Conclusion - Where do we go from here? Session keywords: technology, online record-keeping, students, teachers, program administration, student service

A Comparison of Initial and Subsequent Follow-Up Strobovideolaryngoscopic Examinations in Singers.

OBJECTIVES: Previous studies have identified abnormal findings in up to 86.1% of singers on initial screening strobovideolaryngoscopy (SVL) examinations. No studies have compared the prevalence of abnormalities in singers on their subsequent follow-up SVL. Our study evaluates the frequency of these findings in both the initial and subsequent examinations. METHODS: Retrospective charts and SVL reports were reviewed on students from an opera conservatory from 1993 to 2014. All students had initial screening SVL, but only students who later returned with acute voice complaints were included in the study (n = 51, 137 follow-up visits). Normal SVL was defined as an examination without structural or functional abnormalities and reflux finding score ≤7. Data were analyzed using the chi-square test. RESULTS: For initial examinations, 90.2% (including reflux) and 88.2% (excluding reflux) were abnormal. In follow-up examinations, 94.9% (including reflux) and 94.2% (excluding reflux) had abnormal findings, which included muscle tension dysphonia (40.1%), vocal fold (VF) masses (unilateral 48.9%, bilateral 30.7%), vascular abnormalities (unilateral 27.0%, bilateral 5.8%), sulcus (unilateral 17.5%, bilateral 5.1%), VF hypomobility (unilateral 36.3%, bilateral 5.9%), phase (30.6%) and amplitude (44.8%) asymmetries, and glottic insufficiency (49.3%). Follow-up examinations revealed a significant increase in laryngopharyngeal reflux (χ(2) = 7.043; P \u3c 0.05). CONCLUSIONS: We found a higher prevalence of abnormal findings compared with previous studies, which we attributed to a more inclusive definition of abnormal pathologies, improvements in SVL technology, and possibly increased experience with SVL interpretation. This high prevalence of abnormal findings in asymptomatic singers further supports the importance of baseline examinations

Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru.

The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses for a cohort of patients with lymphadenopathy of unknown etiology. 121 Peruvian adults with lymphadenopathy underwent lymph node biopsy for microbiological and histopathological evaluation. Mean patient age was 41 years (Interquartile Range 26-52), 56% were males, and 39% were HIV positive. Patients reported fever (31%), weight loss (23%), and headache (22%); HIV infection was associated with fever (P < 0.05) and gastrointestinal symptoms (P < 0.05). Abnormalities were reported in 40% of chest X-rays (N = 101). Physicians suspected TB in 92 patients (76%), lymphoma in 19 patients (16%), and other malignancy in seven patients (5.8%). Histological diagnoses (N = 117) included tuberculosis (34%), hyperplasia (27%), lymphoma (13%), and nonlymphoma malignancy (14%). Hyperplasia was more common (P < 0.001) and lymphoma less common (P = 0.005) among HIV-positive than HIV-negative patients. There was a trend toward reduced frequency of caseous necrosis in samples from HIV-positive than HIV-negative TB patients (67 versus 93%, P = 0.055). The spectrum of diagnoses was broad, and clinical and radiological features correlated poorly with diagnosis. On the basis of clinical features, physicians over-diagnosed TB, and under-diagnosed malignancy. Although this may not be inappropriate in resource-limited settings where TB is the most frequent easily treatable cause of lymphadenopathy, diagnostic delays can be detrimental to patients with malignancy. It is important that patients with lymphadenopathy undergo a full diagnostic work-up including sampling for histological evaluation to obtain an accurate diagnosis

Seroprevalence of Neospora caninum infection in cattle from Pereira, Colombia

There are over 25.6 million cattle heads in Colombia being the fourth-highest herd in Latin America. This study aimed to describe the seroprevalence of Neospora caninum in cattle from 25 rural farms at Pereira municipality, Risaralda Department, which has a total bovine population of 43,508 animals. A cross-sectional observational study was performed in beef and dairy herds during 2017–2018. A total of 325 animals in 25 herds, with 13 animals per herd, were sampled. A commercial competitive ELISA (cELISA) kit was used to detect N. caninum antibodies. Associated risk factors were analyzed in two different levels: individual animals and herds. For all the independent variables, chi-square (χ2) and Fisher tests were used to assess associations and significance. The overall estimated seropositivity was 20.6% (95%CI 16.2%–25.0%). The seroprevalence by herds was 92.0% ranging from 0.0% to 46.2%. Noteworthy, beef herds had significantly (p = 0.0107) higher seropositivity (50% of them above 35% of seropositivity) compared with those for milk purposes (4.8%) (OR = 20.0; 95%CI 1.2–331.0). Other risk factors were not significantly (p ≥ 0.05) associated with N. caninum seropositivity. Bovine neosporosis may be associated with abortions in both beef and dairy Colombian farms. More studies about the epidemiology, associated factors and consequences, as well as on tools for better diagnosis of bovine abortion, including histopathology and other ancillary tests, should be performed.Fil: Idarraga Bedoya, Samuel E.. Fundación Universitaria Autónoma de las Américas. Facultad de Medicina Veterinaria y Zootecnia; ColombiaFil: Álvarez Chica, Jaime. Fundación Universitaria Autónoma de las Américas. Facultad de Medicina Veterinaria y Zootecnia; ColombiaFil: Bonilla Aldana, D. Katterine. Universidad Tecnológica de Pereira; Colombia. Fundación Universitaria Autónoma de las Américas; ColombiaFil: Moore, Dadin Prando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible - Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; ArgentinaFil: Rodríguez Morales, Alfonso J.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible - Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Universidad Tecnológica de Pereira; Colombia. Fundación Universitaria Autónoma de las Américas; Colombi

Bayesian Analysis for Remote Biosignature Identification on exoEarths (BARBIE) II: Using Grid-Based Nested Sampling in Coronagraphy Observation Simulations for O2 and O3

We present the results for the detectability of the O2 and O3 molecular species in the atmosphere of an Earth-like planet using reflected light at the visible wavelengths. By quantifying the detectability as a function of signal-to-noise ration (SNR), we can constrain the best methods to detect these biosignatures with nest-generation telescopes designed for high-contrast coronagraph. Using 25 bandpasses between 0.515 and 1 micron, and a pre-constructed grid of geometric albedo spectra, we examined the spectral sensitivity needed to detect these species for a range of molecular abundances. We first replicate a modern-Earth twin atmosphere to study the detectability of current O2 and O3 levels, and then expand to a wider range of literature-driven abundances for each molecule. We constrain the optimal 20%, 30%, and 40% bandpasses based on the effective SNR of the data, and define the requirements for the possibility of simultaneous molecular detection. We present our findings of O2 and O3 detectability as functions of SNR, wavelength, and abundance, and discuss how to use these results for optimizing future instrument designs. We find that O2 is detectable between 0.64 and 0.83 micron with moderate-SNR data for abundances near that of modern-Earth and greater, but undetectable for lower abundances consistent with a Proterozoic Earth. O3 is detectable only at very high SNR data in the case of modern-Earth abundances, however it is detectable at low-SNR data for higher O3 abundances that can occur from efficient abiotic O3 production mechanisms.Comment: 16 pages, 10 figures, accepted for publication in the Astronomical Journa

Community standards for open cell migration data

Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited owing to the diversity of experimental protocols and non-standardized output formats. In addition, typically the datasets are not open for reuse. Making the data open and Findable, Accessible, Interoperable, and Reusable (FAIR) will enable meta-analysis, data integration, and data mining. Standardized data formats and controlled vocabularies are essential for building a suitable infrastructure for that purpose but are not available in the cell migration domain. We here present standardization efforts by the Cell Migration Standardisation Organisation (CMSO), an open community-driven organization to facilitate the development of standards for cell migration data. This work will foster the development of improved algorithms and tools and enable secondary analysis of public datasets, ultimately unlocking new knowledge of the complex biological process of cell migration

Older Adults in Service to Society

Older Adults in Service to Societ

Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age

Neospora caninum is recognised for causing cattle abortion, provoking severe economic losses in the livestock industry worldwide. The aim of the present study was to evaluate the reactivation and foetal infection in pregnant heifers inoculated with live N. caninum tachyzoites before puberty. A total of 15 30-month-old pregnant heifers were allocated into four groups: animals inoculated with live tachyzoites of NC-Argentina LP1 isolate before puberty and challenged with live tachyzoites of NC-1 strain at 210 days of gestation (DG) (Group A); animals mock inoculated before puberty and challenged with NC-1 strain at 210 DG (Group B), animals inoculated before puberty but not subsequently challenged (Group C); and noninfected and nonchallenged animals (Group D). The results of this study showed that 100% of animals infected before puberty (Groups A and C) suffered reactivation of the infection at the seventh month of gestation. In addition, in three and two calves from Groups A and C, respectively, congenital infection was confirmed. Interestingly, we provide evidence that the use of live N. caninum tachyzoites in young animals as a strategy to induce protection is neither safe nor effective.EEA BalcarceFil: Hecker, Yanina Paola. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Burucúa, Mercedes. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Fiorani, Franco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Fiorani, Franco. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina.Fil: Maldonado Rivera, Jaime. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina.Fil: Maldonado Rivera, Jaime. Universidad de Cuenca. Facultad de Ciencias Agropecuarias; Ecuador.Fil: Cirone, Karina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Cirone, Karina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina.Fil: Dorsch, Matías. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina.Fil: Dorsch, Matías. Instituto Nacional de Investigación Agropecuaria (INIA). Estación Experimental La Estanzuela; UruguayFil: Cheuquepán Valenzuela, Felipe. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Campero, Lucía. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Cantón, Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Marín, Maia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Ortega Mora, Luis. Universidad Complutense de Madrid. Facultad de Ciencias Veterinarias; EspañaFil: Moore, Dadin Prando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina