81 research outputs found

    Engaging retailers: giving them voice or controlling their voice, a supplier's perspective

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    This full paper from the Marketing and Retail track of BAM 2013 investigates the relationships between suppliers and retailers in the UK convenience store sector in terms of Hirschman's model whereby members of a group can influence it by either expressing their opinions (voice) or leaving it in protest (exit). Suppliers may create loyalty among retailers by raising exit costs and/or allowing them to express their voices. The investigation was carried out using the recorded turnover of the top thirty wholesalers and the major store chains/franchises in 2005-12, publications by the main trade organisation, in the trade press and online, and interviews. The results of the research suggest that the wholesalers do not use cost of exit or enabling retailer voice exclusively; instead they now tend to combine both within their retailer relationship strategies

    Coal Blooded Action Toolkit

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    With this toolkit, your community now has the necessary framework and tools to build a foundation for eliminating pollution from coal, one of the most important steps we can take, in our march to advance Environmental and Climate Justice. Whether you are a leader, partner or participant in a coal campaign, your role is critical to creating change. By following the modules in the Coal Blooded Action Toolkit, your unit will experience writing letters to decision makers, using the media to advance your cause, organizing community meetings, negotiating with plant owners, etc., towards the ends of reduction of harmful pollution, improving health outcomes, increasing investment in energy efficiency and renewable energy, creating sustainable, healthy jobs/careers, and more. These activities were designed for communities to succeed and most importantly, use them as tools to do so

    Uncovering the hidden value of networks: the complexity of small retailers' relationships

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    Small retailers make a significant impact on the national and local economy but their role can be underestimated by both themselves and their stakeholders who include local and national suppliers, customers, local authorities, trade bodies, business support agencies and national regulators. This underestimation may be down to the complexity of the retailers relationships with the outside world. This seminar will bring together findings from various commissioned research that Keith and Jacqui have conducted for clients including the department for Business Innovation and Skills, the Welsh Assembly, Local Better Regulation Office, SPAR UK, Lancaster University Institute of Family Business, Blakemores and CJ Langs. The seminar will examine the relationship these retailers can have with their local and national supply chains and how these impact on the local economy. Specifically the seminar will follow the process of a group of small retailers as they campaign against planning permission for a large supermarket. This case study highlights how these relationships influence the actions of the retailers to increasing competition from major multiples. The case study will then examine why the depth and value of these relationships can remain obscured from local authorities even at a time when the retail market place is under the closest scrutiny. The seminar will conclude with a brief examination of how these relationships could be improved

    Residential school placements for children and young people with intellectual disabilities: their use and implications for adult social care

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    Out of area residential placements are associated with a range of poor outcomes for adults with intellectual disabilities and behaviours that challenge. In recent years there has been an increased drive to reduce such placements at as early a stage as possible. In this context the current review collates research and policy regarding use of residential schools for children and young people with intellectual disabilities and transition from these settings to adult services. The review highlights that relatively little is known about both use of, and transition from, residential schooling for children and young people with intellectual disabilities in the UK. Thirteen articles are identified: 7 examining the child or families’ experiences before placement, 4 examining outcomes during the placement, and 4 examining the process of transitioning from the placement and longer term outcomes. The methodological quality of articles was often limited. A lack of control groups, independent samples, or adequate sample sizes was particularly notable. Results are discussed in relation to factors that lead to a child’s placement in a residential school, children and families’ experiences of the placement, and outcomes following placement, including the transition process. A number of research priorities are highlighted based on gaps in the literature. Examples of alternative forms of support from clinical practice are provided, with recognition that a multi-element model is likely to be needed to provide high quality support to this group of young people

    Prospectus, June 10, 1991

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    https://spark.parkland.edu/prospectus_1991/1008/thumbnail.jp

    Internet- and mobile-based psychological interventions: applications, efficacy, and potential for improving mental health.

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    The majority of mental health disorders remain untreated. Many limitations of traditional psychological interventions such as limited availability of evidence-based interventions and clinicians could potentially be overcome by providing Internet- and mobile-based psychological interventions (IMIs). This paper is a report of the Taskforce E-Health of the European Federation of Psychologists’ Association and will provide an introduction to the subject, discusses areas of application, and reviews the current evidence regarding the efficacy of IMIs for the prevention and treatment of mental disorders. Meta-analyses based on randomized trials clearly indicate that therapist-guided stand-alone IMIs can result in meaningful benefits for a range of indications including, for example, depression, anxiety, insomnia, or posttraumatic stress disorders. The clinical significance of results of purely self-guided interventions is for many disorders less clear, especially with regard to effects under routine care conditions. Studies on the prevention of mental health disorders (MHD) are promising. Blended concepts, combining traditional face-to-face approaches with Internet- and mobile-based elements might have the potential of increasing the effects of psychological interventions on the one hand or to reduce costs of mental health treatments on the other hand. We also discuss mechanisms of change and the role of the therapist in such approaches, contraindications, potential limitations, and risk involved with IMIs, briefly review the status of the implementation into routine health care across Europe, and discuss confidentiality as well as ethical aspects that need to be taken into account, when implementing IMIs. Internet- and mobile-based psychological interventions have high potential for improving mental health and should be implemented more widely in routine care

    Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial):A Multicentre, Randomised, Controlled Trial

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    RationaleMesenchymal stromal cells (MSCs) may modulate inflammation, promoting repair in COVID-19-related Acute Respiratory Distress Syndrome (ARDS).ObjectivesWe investigated safety and efficacy of ORBCEL-C (CD362-enriched, umbilical cord-derived MSCs) in COVID-related ARDS.MethodsThis multicentre, randomised, double-blind, allocation concealed, placebo-controlled trial (NCT03042143) randomised patients with moderate-to-severe COVID-related ARDS to receive ORBCEL-C (400million cells) or placebo (Plasma-Lyte148).MeasurementsThe primary safety and efficacy outcomes were incidence of serious adverse events and oxygenation index at day 7 respectively. Secondary outcomes included respiratory compliance, driving pressure, PaO2/FiO2 ratio and SOFA score. Clinical outcomes relating to duration of ventilation, length of intensive care unit and hospital stays, and mortality were collected. Long-term follow up included diagnosis of interstitial lung disease at 1 year, and significant medical events and mortality at 2 years. Transcriptomic analysis was performed on whole blood at day 0, 4 and 7.Main results60 participants were recruited (final analysis n=30 ORBCEL-C, n=29 placebo: 1 in placebo group withdrew consent). 6 serious adverse events occurred in the ORBCEL-C and 3 in the placebo group, RR 2.9(0.6-13.2)p=0.25. Day 7 mean[SD] oxygenation index did not differ (ORBCEL-C 98.357.2], placebo 96.667.3). There were no differences in secondary surrogate outcomes, nor mortality at day 28, day 90, 1 or 2 years. There was no difference in prevalence of interstitial lung disease at 1year nor significant medical events up to 2 years. ORBCEL-C modulated the peripheral blood transcriptome.ConclusionORBCEL-C MSCs were safe in moderate-to-severe COVID-related ARDS, but did not improve surrogates of pulmonary organ dysfunction. Clinical trial registration available at www.Clinicaltrialsgov, ID: NCT03042143. This article is open access and distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/)

    Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

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    Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

    Proceedings of Patient Reported Outcome Measure’s (PROMs) Conference Oxford 2017: Advances in Patient Reported Outcomes Research

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    A33-Effects of Out-of-Pocket (OOP) Payments and Financial Distress on Quality of Life (QoL) of People with Parkinson’s (PwP) and their Carer

    Abstracts from the NIHR INVOLVE Conference 2017

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