1,592 research outputs found
Quantum networks reveal quantum nonlocality
The results of local measurements on some composite quantum systems cannot be
reproduced classically. This impossibility, known as quantum nonlocality,
represents a milestone in the foundations of quantum theory. Quantum
nonlocality is also a valuable resource for information processing tasks, e.g.
quantum communication, quantum key distribution, quantum state estimation, or
randomness extraction. Still, deciding if a quantum state is nonlocal remains a
challenging problem. Here we introduce a novel approach to this question: we
study the nonlocal properties of quantum states when distributed and measured
in networks. Using our framework, we show how any one-way entanglement
distillable state leads to nonlocal correlations. Then, we prove that
nonlocality is a non-additive resource, which can be activated. There exist
states, local at the single-copy level, that become nonlocal when taking
several copies of it. Our results imply that the nonlocality of quantum states
strongly depends on the measurement context.Comment: 4 + 3 pages, 4 figure
Occurrence of Mansonella ozzardi diagnosed using a polycarbonate membrane in a riverside population of Lábrea in the Western Brazilian Amazon
Enhanced error estimator based on a nearly equilibrated moving least squares recovery technique for FEM and XFEM
In this paper a new technique aimed to obtain accurate estimates of the error
in energy norm using a moving least squares (MLS) recovery-based procedure is
presented. We explore the capabilities of a recovery technique based on an
enhanced MLS fitting, which directly provides continuous interpolated fields,
to obtain estimates of the error in energy norm as an alternative to the
superconvergent patch recovery (SPR). Boundary equilibrium is enforced using a
nearest point approach that modifies the MLS functional. Lagrange multipliers
are used to impose a nearly exact satisfaction of the internal equilibrium
equation. The numerical results show the high accuracy of the proposed error
estimator
Reliability and correlation analysis of computed methods to convert conventional 2D radiological hindfoot measurements to 3D equivalents using weight bearing CT
Cognitive impairment induced by delta9-tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors
Delta-9-tetrahydrocannabinol (THC), the main psychoactive compound of marijuana, induces numerous undesirable effects, including memory impairments, anxiety, and dependence. Conversely, THC also has potentially therapeutic effects, including analgesia, muscle relaxation, and neuroprotection. However, the mechanisms that dissociate these responses are still not known. Using mice lacking the serotonin receptor 5-HT2A, we revealed that the analgesic and amnesic effects of THC are independent of each other: while amnesia induced by THC disappears in the mutant mice, THC can still promote analgesia in these animals. In subsequent molecular studies, we showed that in specific brain regions involved in memory formation, the receptors for THC and the 5-HT2A receptors work together by physically interacting with each other. Experimentally interfering with this interaction prevented the memory deficits induced by THC, but not its analgesic properties. Our results highlight a novel mechanism by which the beneficial analgesic properties of THC can be dissociated from its cognitive side effects
Evapotranspiração e coeficientes de cultivo da beterraba orgânica sob cobertura morta de leguminosa e gramínea.
As práticas agrícolas que maximizam a produtividade e o uso da água são de vital importância para a agricultura. Assim, foram testados três tipos de manejo do solo com objetivo de determinar a evapotranspiração (ETc) e os coeficientes de cultivo (kc) da beterraba. Os tipos de manejo foram a utilização de coberturas mortas vegetais, denominadas capim cameroon (Pennisetum purpureum), gliricídia (Gliricidia sepium) e solo sem cobertura morta em área experimental do SIPA (Sistema Integrado de Produção Orgânica) localizado em Seropédica, Brasil. A lâmina de irrigação foi estimada com base no balanço de água no solo, cujo monitoramento foi realizado com a técnica da TDR. As ETc acumuladas para a cultura da beterraba foram 59,41; 55,31 e 119,62 mm, respectivamente, para capim cameroon, gliricídia e solo sem cobertura morta. A evapotranspiração de referência (ETo) foi obtida por meio do modelo de Penamn-Monteith. Os valores médios de kc obtidos para as fases inicial, média e final de desenvolvimento foram de 0,39; 0,42 e 1,02; 0,79; 0,76 e 1,18; e 0,56; 0,61 e 0,84, respectivamente, para capim cameroon, gliricídia e solo sem cobertura morta. O uso da cobertura do solo com gramínea ou leguminosa minimizou de forma expressiva a demanda hídrica da cultura da beterraba (Beta vulgaris)
P. brasiliensis virulence is affected by SconC, the negative regulator of inorganic sulfur assimilation
Conidia/mycelium-to-yeast transition of Paracoccidioidesbrasiliensis is a critical step for the establishment of paracoccidioidomycosis, a systemic mycosis endemic in Latin America. Thus, knowledge of the factors that mediate this transition is of major importance for the design of intervention strategies. So far, the only known pre-requisites for the accomplishment of the morphological transition are the temperature shift to 37°C and the availability of organic sulfur compounds. In this study, we investigated the auxotrophic nature to organic sulfur of the yeast phase of Paracoccidioides, with special attention to P. brasiliensis species. For this, we addressed the role of SconCp, the negative regulator of the inorganic sulfur assimilation pathway, in the dimorphism and virulence of this pathogen. We show that down-regulation of SCONC allows initial steps of mycelium-to-yeast transition in the absence of organic sulfur compounds, contrarily to the wild-type fungus that cannot undergo mycelium-to-yeast transition under such conditions. However, SCONC down-regulated transformants were unable to sustain yeast growth using inorganic sulfur compounds only. Moreover, pulses with inorganic sulfur in SCONC down-regulated transformants triggered an increase of the inorganic sulfur metabolism, which culminated in a drastic reduction of the ATP and NADPH cellular levels and in higher oxidative stress. Importantly, the down-regulation of SCONC resulted in a decreased virulence of P. brasiliensis, as validated in an in vivo model of infection. Overall, our findings shed light on the inability of P. brasiliensis yeast to rely on inorganic sulfur compounds, correlating its metabolism with cellular energy and redox imbalances. Furthermore, the data herein presented reveal SconCp as a novel virulence determinant of P. brasiliensis.J.F.M. and J.G.R. were supported by a PhD grant from Fundacao para a Ciencia e Tecnologia (FCT). This work was supported by a grant from FCT (PTDC/BIA-MIC/108309/2008). M. Sturme. and M. Saraiva are Ciencia 2008 fellows. The authors would also like to thank FAPESP (Fundacao para Amparo a Pesquisa do Estado de Sao Paulo) and CNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico) for financial support. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
Probing natural SUSY from stop pair production at the LHC
We consider the natural supersymmetry scenario in the framework of the
R-parity conserving minimal supersymmetric standard model (called natural MSSM)
and examine the observability of stop pair production at the LHC. We first scan
the parameters of this scenario under various experimental constraints,
including the SM-like Higgs boson mass, the indirect limits from precision
electroweak data and B-decays. Then in the allowed parameter space we study the
stop pair production at the LHC followed by the stop decay into a top quark
plus a lightest neutralino or into a bottom quark plus a chargino. From
detailed Monte Carlo simulations of the signals and backgrounds, we find the
two decay modes are complementary to each other in probing the stop pair
production, and the LHC with TeV and 100 luminosity is
capable of discovering the stop predicted in natural MSSM up to 450 GeV. If no
excess events were observed at the LHC, the 95% C.L. exclusion limits of the
stop masses can reach around 537 GeV.Comment: 19 pages, 10 figures, version accepted by JHE
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