11 research outputs found
White muscle disease in three selenium deficient beef and dairy calves in Argentina and Uruguay. (Doença do mĂșsculo branco em trĂȘs bezerros para carne e leite deficientes em selĂȘnio na Argentina e Uruguai).
ABSTRACT:White muscle disease (WMD), nutritional myodegeneration or enzootic muscular dystrophy, is a nutritional condition associated with selenium and/or vitamin E deficiency in ruminants. These elements are constituents of the major body antioxidant systems. Depletion of selenium results in oxidative damage to cardiac and skeletal muscle cells, resulting in myodegeneration and myonecrosis, typical lesions of WMD. Selenium deficiency is common in South America, but WMD is underreported. This research describes clinical, biochemical and pathological findings in two episodes of WMD associated with selenium deficiency in beef and dairy calves in Argentina and Uruguay with concurrent copper deficiency in one of them, which resulted in spontaneous calf mortality. Further studies are necessary to estimate the true incidence and economic impact of clinical and subclinical mineral deficiencies in livestock production systems in the southern cone of South America.RESUMO:Doença do mĂșsculo branco (DMB), miodegeneração nutricional ou distrofia muscular enzoĂłtica Ă© uma condição nutricional associada Ă deficiĂȘncia de selĂȘnio e/ou vitamina E em ruminantes. Esses elementos sĂŁo constituintes dos principais sistemas antioxidantes do corpo. O esgotamento de selĂȘnio resulta em dano oxidativo Ă s cĂ©lulas musculares cardĂacas e esquelĂ©ticas, resultando em miodegeneração e mionecrose, lesĂ”es tĂpicas da DMB. A deficiĂȘncia de selĂȘnio Ă© comum na AmĂ©rica do Sul, mas a DMB estĂĄ subnotificada. Este trabalho descreve os achados clĂnicos, bioquĂmicos e patolĂłgicos em dois surtos de DMB associados Ă deficiĂȘncia de selĂȘnio em bezerros para carne e leite na Argentina e Uruguai com concomitante deficiĂȘncia de cobre em um surto, que resultaram em mortalidade espontĂąnea de bezerros. SĂŁo necessĂĄrios mais estudos para estimar a verdadeira incidĂȘncia e impacto econĂŽmico das deficiĂȘncias minerais clĂnicas e subclĂnicas nos sistemas de produção pecuĂĄria no sul da AmĂ©rica do Sul
Flexibility and adaptation of the neural substrate that supports maternal behavior in mammals
Maternal behavior is species-specific and expressed under different physiological conditions, and contexts. It is the result of neural processes that support different forms (e.g. postpartum, cycling sensitized and spontaneous maternal behavior) and modalities of mother-offspring interaction (e.g. maternal interaction with altricial/precocious young; selective/non-selective bond). To understand how the brain adapts to and regulates maternal behavior in different species, and physiological and social conditions we propose new neural models to explain different forms of maternal expression (e.g. sensitized and spontaneous maternal behavior) and the behavioral changes that occur across the postpartum period. We emphasize the changing role of the medial preoptic area in the neural circuitry that supports maternal behavior and the cortical regulation and adjustment of ongoing behavioral performance. Finally, we discuss how our accumulated knowledge about the psychobiology of mothering in animal models supports the validity of animal studies to guide our understanding of human mothering and to improve human welfare and health
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Strong Carbon Features and a Red Early Color in the Underluminous Type Ia SN 2022xkq
We present optical, infrared, ultraviolet, and radio observations of SN 2022xkq, an underluminous fast-declining Type Ia supernova (SN Ia) in NGC 1784 (D â 31 Mpc), from <1 to 180 days after explosion. The high-cadence observations of SN 2022xkq, a photometrically transitional and spectroscopically 91bg-like SN Ia, cover the first days and weeks following explosion, which are critical to distinguishing between explosion scenarios. The early light curve of SN 2022xkq has a red early color and exhibits a flux excess that is more prominent in redder bands; this is the first time such a feature has been seen in a transitional/91bg-like SN Ia. We also present 92 optical and 19 near-infrared (NIR) spectra, beginning 0.4 days after explosion in the optical and 2.6 days after explosion in the NIR. SN 2022xkq exhibits a long-lived C i 1.0693 ÎŒm feature that persists until 5 days post-maximum. We also detect C ii λ6580 in the pre-maximum optical spectra. These lines are evidence for unburnt carbon that is difficult to reconcile with the double detonation of a sub-Chandrasekhar mass white dwarf. No existing explosion model can fully explain the photometric and spectroscopic data set of SN 2022xkq, but the considerable breadth of the observations is ideal for furthering our understanding of the processes that produce faint SNe Ia. © 2023. The Author(s). Published by the American Astronomical Society.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]