20 research outputs found

    BlogMyData: a Virtual Research Environment for collaborative visualization of environmental data

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    Understanding and predicting the Earth system requires the collaborative effort of scientists from many different disciplines and institutions. The National Centre for Earth Observation (NCEO) and the National Centre for Atmospheric Science Climate Group (NCAS-Climate) are both high-profile interdisciplinary research centres involving numerous universities and institutes around the UK and many international collaborators. Both groups make use of the latest numerical models of the climate and earth system, validated by observations, to simulate the environment and its response to forcings such as an increase in greenhouse gas emissions. Their scientists must work together closely to understand the various aspects of these models and assess their strengths and weaknesses.At the present time, collaborations take place chiefly through face-to-face meetings, the scholarly literature and informal electronic exchanges of emails and documents. All of these methods suffer from serious deficiencies that hamper effective collaboration. For practical reasons, face-to-face meetings can be held only infrequently. The scholarly literature does not yet adequately link scientific results to the source data and thought processes that yielded them, and additionally suffers from a very slow turnaround time. Informal exchanges of electronic information commonly lose vital context; for example, scientists typically exchange static visualizations of data (as GIFs or PostScript plots for example), but the recipient cannot easily access the data behind the visualization, or customize the visualization in any way. Emails are rarely published or preserved adequately for future use. The recent adoption of “off the shelf” Wikis and basic blogs has addressed some of these issues, but does not usually address specific scientific needs or enable the interactive visualization of data

    The evaluation of retinal nerve fiber thickness in chonic obtructive lung disease with optical cohorence tomograpy.

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    Kronik obstrüktif akciğer hastalığının (KOAH) retina sinir lifi tabakası (RSLT) üzerindeki etkisini optik koherens tomografi (OCT), (Stratus OCT-3) ile değerlendirmek ve yaşı uygun sağlıklı bireylerle karşılaştırmaktır.KOAH tanısı konulan veya KOAH tanısıyla takibi yapılan 30 olgu ile 30 sağlıklı gönüllü çalışmaya dahil edilmiştir. Tüm olguların tam bir oftalmolojik muayeneyi takiben OCT fast RNFL protokolü ile ölçümleri yapıldı.Değerlendirilen OCT parametrelerinde, ortalama RSLT değerleri KOAH grubunda sağlıklı kontrol grubuna göre anlamlı derecede kalın bulundu (p<0.001). KOAH grubunda üst kadran ve temporal kadran değerleri (141.07±18.18, 88.37±23.12, sırasıyla), kontrol grubuna (130.17±14.78, 78.30±13.62, sırasıyla) göre istatistiksel olarak anlamlı yüksek bulundu (p=0.013, 0.044, sırasıyla), fakat nazal ve alt kadran RSLT değerleri açısından iki grup arasında anlamlı fark bulunmadı. Olguların RSLT değerleri ile hastalık süresi karşılaştırıldığında, üst kadrana ait RSLT kalınlığı hastalık süresi ile azalmaktaydı (Pearson=-0.375, p<0.05). Tedavi süresi ile karşılaştırıldığında ortalama RSLT kalınlığının da süreyle parelel olarak azaldığı gösterildi (Pearson=-0.537, p<0.05). Olgular hastalığın evresine göre gruplandırıldığında, evre IV KOAH grubunda ortalama RSLT evre III'e göre daha kalın bulundu, ancak fark anlamlı değildi (p=0.39). Diabetes mellitus, hiperkolesterolemi, yaş, sigara kullanımının RSLT üzerine etkisi anlamlı bulunmadı. Kalp hastalığının RSLT kalınlığını arttırdığını, hipertansiyonun ise RSLT kalınlığını azalttığı görüldü.he purpose of this study was to measure the retinal nerve fiber layer (RNFL) thickness of patients with chronic obstructive lung disease (COPD) by using optical coherence tomography (OCT), (Stratus OCT-3) and to compare the measurements with those obtained from the healthy subjects.Thirty patients with COPD and 30 healthy volunteers were included into this study. After ocular examination, all subjects underwent fast RNFL analysis measured by OCT.The mean RNFL thickness value of the COPD group was statistically higher compared to the control group (p<0.001). RNFL thickness in superior and temporal quadrants of the COPD group (141.07±18.18, 88.37±23.12, respectively) were thicker than the control group (130.17±14.78, 78.30±13.62, respectively) which was statistically significant (p=0.013, 0.044, respectively), however there was no difference in RNFL thickness values of the nasal and inferior quadrants. The RNFL thickness of the superior quadrant showed a decrease with the duration of the disease (Pearson=-0.375, p<0.05) and the mean RNFL thickness was decreased with the duration of treatment (Pearson=-0.537, p<0.05). When the COPD subjects classified according to the stage of the disease, the mean RNFL was more thicker in stage IV COPD group compared with stage III COPD group, but the difference was not significant (p=0.39). Diabetes mellitus, hypercholesterolemia, and smoking had no statistically significant effects on the RNFL, whereas the RNFL thickness increased in cardiac disease and decreased in hypertension
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