2,571 research outputs found
Effects of f(R) Model on the Dynamical Instability of Expansionfree Gravitational Collapse
Dark energy models based on f(R) theory have been extensively studied in
literature to realize the late time acceleration. In this paper, we have chosen
a viable f(R) model and discussed its effects on the dynamical instability of
expansionfree fluid evolution generating a central vacuum cavity. For this
purpose, contracted Bianchi identities are obtained for both the usual matter
as well as dark source. The term dark source is named to the higher order
curvature corrections arising from f(R) gravity. The perturbation scheme is
applied and different terms belonging to Newtonian and post Newtonian regimes
are identified. It is found that instability range of expansionfree fluid on
external boundary as well as on internal vacuum cavity is independent of
adiabatic index but depends upon the density profile, pressure
anisotropy and f(R) model.Comment: 26 pages, no figure. arXiv admin note: text overlap with
arXiv:1108.266
A Generating Function for all Semi-Magic Squares and the Volume of the Birkhoff Polytope
We present a multivariate generating function for all n x n nonnegative
integral matrices with all row and column sums equal to a positive integer t,
the so called semi-magic squares. As a consequence we obtain formulas for all
coefficients of the Ehrhart polynomial of the polytope B_n of n x n
doubly-stochastic matrices, also known as the Birkhoff polytope. In particular
we derive formulas for the volumes of B_n and any of its faces.Comment: 24 pages, 1 figure. To appear in Journal of Algebraic Combinatoric
The association of cognitive and somatic depressive symptoms with depression recognition and outcomes after myocardial infarction
BACKGROUND: Among patients with acute myocardial infarction (AMI), depression is both common and under-recognized. The association of different manifestations of depression, somatic and cognitive, with depression recognition and long-term prognosis is poorly understood. METHODS AND RESULTS: Depression was confirmed in 481 AMI patients enrolled from 21 sites during their index hospitalization with a Patient Health Questionnaire (PHQ-9) score ≥10. Within the PHQ-9, separate somatic and cognitive symptom scores were derived and the independent association between these domains and the clinical recognition of depression, as documented in the medical records, was evaluated. In a separate multisite AMI registry of 2,347 patients, the association between somatic and cognitive depressive symptoms and 4-year all-cause mortality and 1-year all-cause rehospitalization was evaluated. Depression was clinically recognized in 29% (n=140) of patients. Cognitive depressive symptoms (Relative Risk [RR] per Standard Deviation [SD] increase=1.14; 95% confidence interval [CI] 1.03–1.26; p=0.01) were independently associated with depression recognition, while the association for somatic symptoms and recognition (RR=1.04; 95% CI 0.87–1.26; p=0.66) was not significant. However, unadjusted Cox regression analyses found that only somatic depressive symptoms were associated with 4-year mortality (Hazard Ratio [HR] per SD increase=1.22; 95% confidence interval [CI] 1.08–1.39) or 1-year rehospitalization (HR=1.22; 95%CI 1.11–1.33) while cognitive manifestations were not (HR for mortality=1.01; 95%CI 0.89–1.14; HR for rehospitalization=1.01; 95%CI 0.93–1.11). After multivariable adjustment, the association between somatic symptoms and rehospitalization persisted (HR=1.16; 95% CI:1.06–1.27; p=0.01) but was attenuated for mortality (HR=1.07; 95% CI:0.94–1.21; p=0.30). CONCLUSIONS: Depression after AMI was recognized in fewer than 1 in 3 patients. Although cognitive symptoms were associated with recognition of depression, somatic symptoms were associated with long-term outcomes. Comprehensive screening and treatment of both somatic and cognitive symptoms may be necessary to optimize depression recognition and treatment in AMI patients
Circular Semiclassical String solutions on Confining AdS/CFT Backgrounds
We study multiwrapped circular string pulsating in the radial direction of
AdS black hole. We compute the energy of this string as a function of a large
quantum number n. One then could associate it with energy and a quantum number
of states in the dual finite temperature {\cal N}=4 SYM theory as well as three
dimensional pure gauge theory. We observe that the n dependence of the energy
has a universal form. We have also considered pulsating string in the
background of the near-extremal D4-brane solution. Circular pulsating membrane
in M-theory on AdS_7\times S^4 has also been studied.Comment: 14 pages, latex, v2: typos corrected, refs. adde
Self-determined motivation in sport predicts anti-doping motivation and intention: A perspective from the trans-contextual model
Objectives: Motivation in sport has been frequently identified as a key factor of young athletes’ intention of doping in sport, but there has not been any attempt in scrutinizing the motivational mechanism involved. The present study applied the trans-contextual model of motivation to explain the relationship between motivation in a sport context and motivation and the social-cognitive factors (attitude, subjective norm, perceived behavioral control, and intention) from the theory of planned behavior (TPB) in an anti-doping context. Design: A cross-sectional survey was conducted. Methods: Questionnaire data was collected from 410 elite and sub-elite young athletes in Australia (Mean age [17.7 ± 3.9 yr], 55.4% male, Years in sport [9.1 ± 3.2]). We measured the key model variables of study in relation to sport motivation (Behavioral Regulation in Sport Questionnaire), and the motivation (adapted version of the Treatment Self-Regulation Questionnaire) and social cognitive patterns (the theory of planned behavior questionnaire) of doping avoidance. The data was analyzed by variance-based structural equation modeling with bootstrapping of 999 replications. Results: The goodness-of-fit of the hypothesized model was acceptable. The bootstrapped parameter estimates revealed that autonomous motivation and amotivation in sport were positively associated with the corresponding types of motivation for the avoidance of doping. Autonomous motivation, subjective norm, and perceived behavioral control in doping avoidance fully mediated the relationship between autonomous motivation in sport and intention for doping avoidance. Conclusions: The findings support the tenets of the trans-contextual model, and explain how motivation in sport is related to athletes’ motivation and intention with respect to anti-doping behaviors
A case of multiple sclerosis—like relapsing remitting encephalomyelitis following allogeneic hematopoietic stem cell transplantation and a review of the published literature
Complications involving the central nervous system (CNS) occur in 9–14% of patients following allogeneic hematopoietic stem cell transplantation (HSCT), including stroke-like episodes, demyelination, encephalitis, and nonspecific neurological symptoms. Here we report a case of multiple sclerosis (MS) like relapsing remitting encephalomyelitis following allogeneic HSCT, which did not respond to disease modifying therapies (DMTs) and “domino” autologous HSCT. A 53-year-old male was treated with allogeneic HSCT for lymphoid blast transformation of chronic myeloid leukemia. Ten months later he presented with confusion, slurred speech, left sided facial weakness and ataxia. A magnetic resonance imaging brain scan showed multiple enhancing tumefactive lesions. Neuromyelitis optica (NMO) and myelin oligodendrocyte glycoprotein (MOG) antibodies were negative. After extensive investigations for infections, autoimmune disorders and recurrence of malignancy, he underwent brain biopsy, which showed a macrophage rich lesion with severe myelin loss but axonal preservation indicating a demyelinating pathology. Although his symptoms improved with corticosteroids, he relapsed five months later. In the absence of any systemic features suggesting graft versus host disease (GvHD), his presentation was thought to be compatible with MS. The illness followed an aggressive course that did not respond to glatiramer acetate and natalizumab. He was therefore treated with “domino” autologous HSCT, which also failed to induce long-term remission. Despite further treatment with ocrelizumab, he died of progressive disease. An autopsy limited to the examination of brain revealed multifocal destructive leukoencephalopathy with severe myelin and axonal loss. Immunohistochemistry showed macrophage located in the perivascular area, with no T or B lymphocytes. The appearance was unusual and not typical for chronic MS plaques. Reported cases of CNS demyelination following allogeneic HSCT are very limited in the literature, especially in relation to histopathological examination. Although the clinical disease course of our patient following allogeneic HSCT resembled an “MS-like” relapsing remitting encephalomyelitis, the autopsy examination did not show any evidence of active inflammation. The impact of DMTs and HSCT on the histological appearance of “MS-like” CNS pathologies is unknown. Therefore, reporting this and similar cases will improve our awareness and understanding of underlying disease mechanisms
The Higher Derivative Expansion of the Effective Action by the String-Inspired Method, Part I
The higher derivative expansion of the one-loop effective action for an
external scalar potential is calculated to order O(T**7), using the
string-inspired Bern-Kosower method in the first quantized path integral
formulation. Comparisons are made with standard heat kernel calculations and
with the corresponding Feynman diagrammatic calculation in order to show the
efficiency of the present method.Comment: 13 pages, Plain TEX, 1 figure may be obtained from the authors,
HD-THEP-93-4
Quantum Chaos in Open versus Closed Quantum Dots: Signatures of Interacting Particles
This paper reviews recent studies of mesoscopic fluctuations in transport
through ballistic quantum dots, emphasizing differences between conduction
through open dots and tunneling through nearly isolated dots. Both the open
dots and the tunnel-contacted dots show random, repeatable conductance
fluctuations with universal statistical proper-ties that are accurately
characterized by a variety of theoretical models including random matrix
theory, semiclassical methods and nonlinear sigma model calculations. We apply
these results in open dots to extract the dephasing rate of electrons within
the dot. In the tunneling regime, electron interaction dominates transport
since the tunneling of a single electron onto a small dot may be sufficiently
energetically costly (due to the small capacitance) that conduction is
suppressed altogether. How interactions combine with quantum interference are
best seen in this regime.Comment: 15 pages, 11 figures, PDF 2.1 format, to appear in "Chaos, Solitons &
Fractals
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