8 research outputs found
Ensemble common features technique for lightweight intrusion detection in industrial control system.
- Publication venue
- 'Institute of Electrical and Electronics Engineers (IEEE)'
- Publication date
- 08/05/2023
- Field of study
The integration of the Industrial Control System (ICS) with corporate intranets and the internet has exposed the previously isolated SCADA system to a wide range of cyberattacks. Interestingly, the vulnerabilities in the Modbus protocol, with which the ICS communicates, make data obfuscation and communication between component entities less secure. In this work, we propose a Common Features Technique (CFT) for Lightweight Intrusion Detection based on an ensembled feature selection approach. Our Common Features Technique, which used fewer features, was able to detect intrusion at the same level as models using information gain, Chi-Squared, and Gini Index feature selection techniques datasets after fitting Random Forest (RF), Support Vector Machine (SVM), and K-Nearest Neighbour (KNN) models. More importantly, when p-values were computed, the CFT model computation time and memory usage were statistically significantly different at 95% and 90% Confidence Interval (CI) when compared to the model on the other techniques
Enhancing intrusion detection through data perturbation augmentation strategy.
- Publication venue
- Institute of Electrical and Electronics Engineers (IEEE)
- Publication date
- 15/05/2024
- Field of study
Intrusion data augmentation is an approach used to increase the size of the training data sample to improve the classification capabilities of machine-learning algorithms applied to intrusion detection. In this study, we introduced data perturbation by adding Gaussian noise to the minority class representing the intrusion scenarios. Employing the Divide-Sort, Augment, and Combined (SAC) technique, we performed oversampling on the minority class of two datasets used for training the model. Subsequently, we validated the model to achieve high overall accuracy indicating reliable intrusion detection. The performance of the model on the perturbed dataset was compared with that of the SMOTE and ROSE data augmentation methods. The results revealed that the perturbation of oversampled data exhibited superior and near perfect classification compared with the SMOTE and ROSE data augmentation techniques. The effectiveness of the proposed intrusion detection approach has been demonstrated on the BoT-IoT and smart grid imbalanced datasets, previously used for benchmarking
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
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- Abbas A.M.
- Abbas M.
- Abbasi M.
- Abbott T.
- Abdalaal I.
- Abdel-Galil K.
- Abdelemam R.
- Abdelgawad A.
- Abdelkarim M.
- Abdelkhalek M.
- Abdelmageed A.
- Abdelmawgoud S.
- Abdelmohsen S.
- Abdelrahman A.S.
- Abdelrahman M.
- Abdelwahab K.
- Abdou H.
- Abdulai D.R.
- Abdulkhaleq M.
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- Abdulsalam K.
- Abdulsalam S.
- Abdur-Rahman L.
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- Abdussalam H.O.
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- Šantak G.
- Šimko K.
- Žatecký J.
- Publication venue
- Oxford University Press (OUP)
- Publication date
- 01/07/2023
- Field of study
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
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- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
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- Anastasiadou Sofia
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- Andreani Lorenzo
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- Andrianakis Alexandros
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- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
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- Archer James
- Ardura Francisco
- Aremu Muyiwa
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- Armijos Daniel
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- Atkins William
- Atkinson Kate
- Attwood Joseph
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- Baiocchi Gian Luca
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- Baiyewu Lateef Ayodele
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- Banky Balazs
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- Barra Fabio
- Barranquero Alberto G.
- Barugola Giuliano
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- Bashir Mahmod
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- Batista Sylvia
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- Bawa Ashvind
- Bawa Sayesha
- Bayhan Hüseyin
- Bayo Heura Llaquet
- Bazzi Nagham
- Beamish Andrew
- Beasley Nigel
- Beatty Jasmine Winter
- Becerra Angel
- Bedada Alemayehu Ginbo
- Bedzhanyan Arkady
- Begum Farzana
- Beisenov Bekzat
- Bellio Gabriele
- Bello Usman Mohammed
- Bellés Ana Ciscar
- Belzile Etienne
- Benamar Safia
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- Bergkvist David Julià
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- Van Den Eynde Jef
- Van Goor Harry
- Van Vliet Helen
- Van Wyk Naomi Natasha
- Vanni Camilla
- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
- Veglia Antonella
- Velten Markus
- Velázquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
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- Vilaró Blanca Capdevila
- Villanueva Julio
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- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Vásquez Javier Alberto Gutiérrez
- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
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- Warner Christian
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- White Stuart
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- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
The effects of relocation to a new hospital on the first anaesthetic weekend call
- Publication venue
- 'African Journals Online (AJOL)'
- Publication date
- 14/03/2008
- Field of study
Background: Relocation of a hospital is a big challenge anywhere in the world. The aim of this study is to document our regional experience, highlight the challenges faced and crisis management with the possibility of identifying features of relocation strategy that can be employed in the future.
Methods: This is a prospective observational study of all emergency anaesthesia performed during the first weekend call following relocation of the teaching hospital. Photographs were taken, events were documented and records from the anaesthetic charts were analyzed.
Results: Five emergency Caesarean sections were performed. There were no surgical emergency operations. One theatre was designated for all emergencies. Intra-hospital transfer of patients between the labour ward, theatre, special care baby unit and postnatal ward over some distance was required. Some drugs particularly neostigmine and neonatal resuscitaire were still unpacked. Four out of five caesarean sections were performed under spinal anaesthesia. Outcome of neonatal resuscitation was satisfactory.
Conclusion: Relocation of a hospital is challenging. Improvisation and application of basic knowledge and skills while maintaining a good ambience were necessary. Adequate planning, rehearsals and good leadership will minimize the problems.
Keywords: Relocation, Anaesthetic weekend-call, ChallengesPHMJ Vol. 2 (2) 2008: pp. 140-14
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
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- Publication venue
- country:GB
- Publication date
- 01/01/2023
- Field of study
Background: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods: This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was coprioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low-middle-income countries. Results: In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of 'single-use' consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low-middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion: This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high- and low-middle-income countries
The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications
- Author
- A. Abd-rouf
- A. Abduljalil
- A. Abdulrahman
- A. Abokris
- A. Abushnaf
- A. Addanfour
- A. Alatresh
- A. Alfari
- A. Alfetore
- A. Algddar
- A. Alghazali
- A. Alhendery Alhendery
- A. Ali
- A. Ali
- A. Alkilani
- A. Alli
- A. Almajbery
- A. Alsayed
- A. Anele
- A. Attia
- A. Basenero
- A. Berhe
- A. Bogoslovskiy
- A. Dasrath
- A. Dodiyi-Manuel
- A. Ehouni
- A. Elmgadmi
- A. Elshikhy
- A. Elwerfelli
- A. Feituri
- A. Gakenia
- A. Ganesh
- A. Garrido Lopez
- A. Ghnain
- A. Hdud
- A. Ibrahim Abdelatif
- A. Issoufou
- A. Jaber
- A. Juwid
- A. Khamajeet
- A. Maharaj
- A. Maharaj
- A. Mallier Peter
- A. Manneh
- A. Mansour
- A. Metali
- A. Mlotshwa
- A. Mohamed
- A. Mohamed
- A. Mohamed
- A. Mohamed
- A. Mohamed
- A. Muturi
- A. Mwale
- A. Nansook
- A. Onyegbule
- A. Prosper
- A. Rabemazava
- A. Sarkin-Pawa
- A. Shubba
- A. Sohoub
- A. Steyn
- A. Swaleh
- A. Tarhuni
- A. Thotharam
- A. Wafa
- A. Wafula
- A. Zidan
- A. Zo
- A.A. Alraheem
- A.A. Altagazi
- A.A. Aribi
- A.A. Eshwehdi
- A.A. Kornilov
- A.A. Munyika
- A.A. Sheshe
- A.A. Yahya
- A.A. Yunus
- A.A.G. Gomati
- A.B. Muhammad
- A.B. Zerihun
- A.C. Castro
- A.D. Aldarrat
- A.D. Maharaj
- A.E.T. Ayebale
- A.F.X. Agaba
- A.G.B. Andriamampionona
- A.G.L. Rocher
- A.H. Harissou
- A.H. Hery
- A.H.N. Rakotoarisoa
- A.H.R. Rakotoarijaona
- A.I. Ibrahim
- A.I. Levin
- A.I. Yahya
- A.J. Szpytko
- A.J. Vermeulen
- A.J.M. Lumbamba
- A.K. Egote
- A.K. Kintu
- A.K. Koledale
- A.L. AL Samateh
- A.L. Samateh
- A.M. Baloyi
- A.M. Elghallal
- A.M. Elghobashy
- A.M. Elzufri
- A.M. Iraya
- A.M. Kilembe
- A.M. Kukembila
- A.M. Macheka
- A.M. Mohamed
- A.M. Ngalala
- A.M. Torborg
- A.N. Kabongo
- A.N.J.D. Alberts
- A.O. Adisa
- A.O. Omigbodun
- A.O. Osinowo
- A.O. Ousseini
- A.O. Usenbo
- A.P. Gatheru
- A.P. Patience
- A.R.W. Mungherera
- A.S. Shkirban
- A.S. Singh
- A.S. Yusuf
- A.S.B. Benamour
- A.S.M. Madsen
- A.T. Robelie
- A.T.M. Masiyambiri
- A.Z. Elzoway
- A.Z. Machowski
- A.Z. Zeiton
- Abdulaziz M. Elkhogia
- Adam Hewitt-Smith
- Adams
- Ahmadou L. Samateh
- Akinyinka O. Omigbodun
- Akwasi Antwi-Kusi
- Al.-A. Amer
- Al.-J. Ahmed
- Alex M. Makupe
- Ambroise Guegni
- Amina. Kalisa
- Anatole Atomabe
- Andrew K.N. Ndonga
- Anthony R. Reed
- Apollo. Basenero
- B. Ahmed
- B. Alsellabi
- B. Chrirangi
- B. Church
- B. Dedekind
- B. Gadi
- B. Githae
- B. Kipng’etich
- B. Kiprop
- B. Lerutla
- B. Ntueba
- B. Rink
- B. Thakoor
- B. Veerasamy
- B.A. Albakosh
- B.A. Dokolwana
- B.B. Afolabi
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- W. Njuguna
- W. Rois
- W. Sam-Awortwi
- W.A.G. Simo
- W.A.P. Ras
- W.D. Mbombo
- W.M. du Plessis
- W.M.S. Mbuyi
- W.P. Kuhn
- W.P. Makhaye
- W.V.J. Koperski
- Wong
- Y. Baitchu
- Y. Coulibaly
- Y. le Manach
- Y. Mampangula
- Y. Najm
- Y. Yakubu
- Y.A. Ali
- Y.B. Adamu
- Y.B. Bwambale
- Y.B.M. Freeman
- Y.G. Gandy
- Y.M. Yangazov
- Y.Y. Kutor
- Yannick Le Manach
- Youssouf Coulibaly
- Z. Farina
- Z. Imessaoudene
- Z. Nibe
- Z. Nyatela-Akinrinmade
- Z. Rakhda
- Z.S. Elghazal
- Z.S. Jamal
- Zipporah W.W. Ngumi
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/09/2018
- Field of study
Background:
The African Surgical Outcomes Study (ASOS) showed that surgical patients in Africa have a mortality twice the global average. Existing risk assessment tools are not valid for use in this population because the pattern of risk for poor outcomes differs from high-income countries. The objective of this study was to derive and validate a simple, preoperative risk stratification tool to identify African surgical patients at risk for in-hospital postoperative mortality and severe complications.
Methods:
ASOS was a 7-day prospective cohort study of adult patients undergoing surgery in Africa. The ASOS Surgical Risk Calculator was constructed with a multivariable logistic regression model for the outcome of in-hospital mortality and severe postoperative complications. The following preoperative risk factors were entered into the model; age, sex, smoking status, ASA physical status, preoperative chronic comorbid conditions, indication for surgery, urgency, severity, and type of surgery.
Results:
The model was derived from 8799 patients from 168 African hospitals. The composite outcome of severe postoperative complications and death occurred in 423/8799 (4.8%) patients. The ASOS Surgical Risk Calculator includes the following risk factors: age, ASA physical status, indication for surgery, urgency, severity, and type of surgery. The model showed good discrimination with an area under the receiver operating characteristic curve of 0.805 and good calibration with c-statistic corrected for optimism of 0.784.
Conclusions:
This simple preoperative risk calculator could be used to identify high-risk surgical patients in African hospitals and facilitate increased postoperative surveillance.
© 2018 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Medical Research Council of South Africa gran
Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study.
- Author
- A Abd-rouf
- A Abduljalil
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- TM Chokwe
- TM Mahureva
- TM Mhlari
- TM Mwiti
- TN Nkuebe
- TN Shangase
- TNO Chaibva
- TO Ogundiran
- Tonya M Esterhuizen
- Tonya M Esterhuizen MSc
- TPR Ramchurn
- Traoré Abdoulaye
- Traoré Ibrahim
- TS Abuzalout
- TS Alkesa
- TS Mohamed
- TS Ngcobo
- TSK Lyimo
- TW Munyaradzi
- TWA Anabah
- Usha Singh
- Ushmaben Patel-Mujajati
- Ushmaben Patel-Mujajati MMed Anaes
- UV Jaganath
- V Athanse
- V Dehal
- V Govindasamy
- V Makhanya
- V Mwenda
- V Pillay
- V Ryndine
- V Sinoamadi
- Veekash Gobin
- Veekash Gobin MD
- VEM Musiba
- VK Kusweje
- VK Mushangwe
- VL Koller
- VL Moses
- VM Gacii
- VM Mtongwe
- VMK Kissoon
- VN Nziene
- VT Manzini
- W Abozaid
- W Conradie
- W Kibochi
- W Kuhn
- W Mathangani
- W Njuguna
- W Rois
- W Sam-Awortwi (Jnr)
- WAG Simo
- WAP Ras
- WD Mbombo
- WJ Koperski
- WM du Plessis
- WMS Mbuyi
- WP Kuhn
- WP Makhaye
- Y Baitchu
- Y Mampangula
- Y Najm
- Y Yakubu
- YA Ali
- Yannick Le Manach
- YB Adamu
- YB Bwambale
- YBM Freeman
- YG Gandy
- YM Yangazov
- Youssouf Coulibaly
- YY Kutor
- Z Farina
- Z Imessaoudene
- Z Nibe
- Z Nyatela-Akinrinmade
- Z Rakhda
- Zipporah W W Ngumi ProfFFARCS
- Zipporah WW Ngumi
- ZS Elghazal
- ZS Jamal
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/04/2019
- Field of study
BACKGROUND: Maternal and neonatal mortality is high in Africa, but few large, prospective studies have been done to investigate the risk factors associated with these poor maternal and neonatal outcomes. METHODS: A 7-day, international, prospective, observational cohort study was done in patients having caesarean delivery in 183 hospitals across 22 countries in Africa. The inclusion criteria were all consecutive patients (aged ≥18 years) admitted to participating centres having elective and non-elective caesarean delivery during the 7-day study cohort period. To ensure a representative sample, each hospital had to provide data for 90% of the eligible patients during the recruitment week. The primary outcome was in-hospital maternal mortality and complications, which were assessed by local investigators. The study was registered on the South African National Health Research Database, number KZ_2015RP7_22, and on ClinicalTrials.gov, number NCT03044899. FINDINGS: Between February, 2016, and May, 2016, 3792 patients were recruited from hospitals across Africa. 3685 were included in the postoperative complications analysis (107 missing data) and 3684 were included in the maternal mortality analysis (108 missing data). These hospitals had a combined number of specialist surgeons, obstetricians, and anaesthetists totalling 0·7 per 100 000 population (IQR 0·2-2·0). Maternal mortality was 20 (0·5%) of 3684 patients (95% CI 0·3-0·8). Complications occurred in 633 (17·4%) of 3636 mothers (16·2-18·6), which were predominantly severe intraoperative and postoperative bleeding (136 [3·8%] of 3612 mothers). Maternal mortality was independently associated with a preoperative presentation of placenta praevia, placental abruption, ruptured uterus, antepartum haemorrhage (odds ratio 4·47 [95% CI 1·46-13·65]), and perioperative severe obstetric haemorrhage (5·87 [1·99-17·34]) or anaesthesia complications (11·47 (1·20-109·20]). Neonatal mortality was 153 (4·4%) of 3506 infants (95% CI 3·7-5·0). INTERPRETATION: Maternal mortality after caesarean delivery in Africa is 50 times higher than that of high-income countries and is driven by peripartum haemorrhage and anaesthesia complications. Neonatal mortality is double the global average. Early identification and appropriate management of mothers at risk of peripartum haemorrhage might improve maternal and neonatal outcomes in Africa. FUNDING: Medical Research Council of South Africa.Medical Research Council of South Africa