208 research outputs found
A survey of location inference techniques on Twitter
The increasing popularity of the social networking service, Twitter, has made it more involved in day-to-day communications, strengthening social relationships and information dissemination. Conversations on Twitter are now being explored as indicators within early warning systems to alert of imminent natural disasters such as earthquakes and aid prompt emergency responses to crime. Producers are privileged to have limitless access to market perception from consumer comments on social media and microblogs. Targeted advertising can be made more effective based on user profile information such as demography, interests and location. While these applications have proven beneficial, the ability to effectively infer the location of Twitter users has even more immense value. However, accurately identifying where a message originated from or an author’s location remains a challenge, thus essentially driving research in that regard. In this paper, we survey a range of techniques applied to infer the location of Twitter users from inception to state of the art. We find significant improvements over time in the granularity levels and better accuracy with results driven by refinements to algorithms and inclusion of more spatial features
Validation and Performance of the LHC Cryogenic System through Commissioning of the First Sector
The cryogenic system [1] for the Large Hadron Collider accelerator is presently in its final phase of commissioning at nominal operating conditions. The refrigeration capacity for the LHC is produced using eight large cryogenic plants and eight 1.8 K refrigeration units installed on five cryogenic islands. Machine cryogenic equipment is installed in a 26.7-km circumference ring deep underground tunnel and are maintained at their nominal operating conditions via a distribution system consisting of transfer lines, cold interconnection boxes at each cryogenic island and a cryogenic distribution line. The functional analysis of the whole system during all operating conditions was established and validated during the first sector commissioning in order to maximize the system availability. Analysis, operating modes, main failure scenarios, results and performance of the cryogenic system are presented
Design, Production and First Commissioning Results of the Electrical Feedboxes of the LHC
A total of 44 CERN designed cryogenic electrical feedboxes are needed to power the LHC superconducting magnets. The feedboxes include more than 1000 superconducting circuits fed by high temperature superconductor and conventional current leads ranging from 120 A to 13 kA. In addition to providing the electrical current to the superconducting circuits, they also ensure specific mechanical and cryogenic functions for the LHC. The paper focuses on the main design aspects and related production operations and gives an overview of specific technologies employed. Results of the commissioning of the feedboxes of the first LHC sectors are presented
Hole Dispersions for Antiferromagnetic Spin-1/2 Two-Leg Ladders by Self-Similar Continuous Unitary Transformations
The hole-doped antiferromagnetic spin-1/2 two-leg ladder is an important
model system for the high- superconductors based on cuprates. Using the
technique of self-similar continuous unitary transformations we derive
effective Hamiltonians for the charge motion in these ladders. The key
advantage of this technique is that it provides effective models explicitly in
the thermodynamic limit. A real space restriction of the generator of the
transformation allows us to explore the experimentally relevant parameter
space. From the effective Hamiltonians we calculate the dispersions for single
holes. Further calculations will enable the calculation of the interaction of
two holes so that a handle of Cooper pair formation is within reach.Comment: 16 pages, 26 figure
Field-controlled magnetic order in the quantum spin-ladder system (Hpip)2CuBr4
International audienceNeutron diffraction is used to investigate the field-induced, antiferromagnetically ordered state in the two-leg spin-ladder material (Hpip)2CuBr4. This “classical” phase, a consequence of weak interladder coupling, is nevertheless highly unconventional: its properties are influenced strongly by the spin Luttinger-liquid state of the ladder subunits. We determine directly the order parameter (transverse magnetization), the ordering temperature, the spin structure, and the critical exponents around the transition. We introduce a minimal microscopic model for the interladder coupling and calculate the quantum fluctuation corrections to the mean-field interaction
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis
Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss: Links With Metabolic and Low-Grade Inflammation Markers
International audienceOBJECTIVE Obesity alters gut microbiota ecology and associates with low-grade inflammation in humans. Roux-en-Y gastric bypass (RYGB) surgery is one of the most efficient procedures for the treatment of morbid obesity resulting in drastic weight loss and improvement of metabolic and inflammatory status. We analyzed the impact of RYGB on the modifications of gut microbiota and examined links with adaptations associated with this procedure. RESEARCH DESIGN AND METHODS Gut microbiota was profiled from fecal samples by real-time quantitative PCR in 13 lean control subjects and in 30 obese individuals (with seven type 2 diabetics) explored before (M0), 3 months (M3), and 6 months (M6) after RYGB. RESULTS Four major findings are highlighted: 1) Bacteroides/Prevotella group was lower in obese subjects than in control subjects at MO and increased at M3. It was negatively correlated with corpulence, but the correlation depended highly on caloric intake; 2) Escherichia coli species increased at M3 and inversely correlated with fat mass and leptin levels independently of changes in food intake; 3) lactic acid bacteria including Lacto-bacillus/Leuconostoc/Pediococcus group and Bifidobacterium genus decreased at M3; and 4) Faecalibacterium prausnitzii species was lower in subjects with diabetes and associated negatively with inflammatory markers at MO and throughout the follow-up after surgery independently of changes in food intake. CONCLUSIONS These results suggest that components of the dominant gut microbiota rapidly adapt in a starvation-like situation induced by RYGB while the F. prausnitzii species is directly linked to the reduction in low-grade inflammation state in obesity and diabetes independently of calorie intake. Diabetes 59:3049-3057, 201
Endoscopic internal drainage for the management of leak, fistula, and collection after sleeve gastrectomy: our experience in 617 consecutive patients
Background: Endoscopy plays a pivotal role in the management of adverse events (AE) following bariatric surgery. Leaks, fistulae, and post-operative collection after sleeve gastrectomy (SG) may occur in up to 10% of cases. Objectives: To evaluate the efficacy and safety of endoscopic internal drainage (EID) for the management of leak, fistula, and collection following SG. Setting: Retrospective, observational, single center study on patients referred from several bariatric surgery departments to an endoscopic referral center. Methods: EID was used as first-line treatment for the management of leaks, fistulae, and collections. Leaks and fistulae were treated with double pigtail stent (DPS) deployment in order to guarantee internal drainage and second intention cavity obliteration. Collections were treated with endoscropic ultrasound (EUS)–guided deployment of DPS or lumen apposing metal stents. Results: A total of 617 patients (83.3% female; mean age, 43.1 yr) were enrolled in the study for leak (n = 300, 48.6%), fistula (n = 285, 46.2%), and collection (n = 32, 5.2%). Median follow-up was 19.5 months. Overall clinical success was 84.7% whereas 15.3% of cases required revisional surgery after EID failure. Clinical success according to type of AE was 89.5%, 78.5%, and 90% for leak, fistula, and collection, respectively. A total of 10 of 547 (1.8%) presented a recurrence during follow-up. A total of 28 (4.5%) AE related to the endoscopic treatment occurred. At univariate logistic regression predictors of failure were: fistula (OR 2.012), combined endoscopic approach (OR 2.319), need for emergency surgery (OR 1.755), and previous endoscopic treatment (OR 4.818). Conclusion: Early EID for the management of leak, fistula, and post-operative collection after SG seems a safe and effective first-line approach with good long-term results
On the intermediate-redshift central stellar mass-halo mass relation, and implications for the evolution of the most massive galaxies since Z~1
The stellar mass-halo mass relation is a key constraint in all semi-analytic, numerical, and semi-empirical models of galaxy formation and evolution. However, its exact shape and redshift dependence remain under debate. Several recent works support a relation in the local universe steeper than previously thought. Based on comparisons with a variety of data on massive central galaxies, we show that this steepening holds up to z ~ 1 for stellar masses M star gsim 2 × 1011 M ?. Specifically, we find significant evidence for a high-mass end slope of ? gsim 0.35-0.70 instead of the usual ? lesssim 0.20-0.30 reported by a number of previous results. When including the independent constraints from the recent Baryon Oscillation Spectroscopic Survey clustering measurements, the data, independent of any systematic errors in stellar masses, tend to favor a model with a very small scatter (lesssim 0.15 dex) in stellar mass at fixed halo mass, in the redshift range z < 0.8 and for M star > 3 × 1011 M ?, suggesting a close connection between massive galaxies and host halos even at relatively recent epochs. We discuss the implications of our results with respect to the evolution of the most massive galaxies since z ~ 1
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