Riesz and Wolff potentials and elliptic equations in variable exponent weak Lebesgue spaces

We prove optimal integrability results for solutions of the p(x)-Laplace equation in the scale of (weak) Lebesgue spaces. To obtain this, we show that variable exponent Riesz and Wolff potentials map L1 to variable exponent weak Lebesgue spaces

INFOGEST static in vitro simulation of gastrointestinal food digestion

peer-reviewedSupplementary information is available at http://dx.doi.org/10.1038/s41596-018-0119-1 or https://www.nature.com/articles/s41596-018-0119-1#Sec45.Developing a mechanistic understanding of the impact of food structure and composition on human health has increasingly involved simulating digestion in the upper gastrointestinal tract. These simulations have used a wide range of different conditions that often have very little physiological relevance, and this impedes the meaningful comparison of results. The standardized protocol presented here is based on an international consensus developed by the COST INFOGEST network. The method is designed to be used with standard laboratory equipment and requires limited experience to encourage a wide range of researchers to adopt it. It is a static digestion method that uses constant ratios of meal to digestive fluids and a constant pH for each step of digestion. This makes the method simple to use but not suitable for simulating digestion kinetics. Using this method, food samples are subjected to sequential oral, gastric and intestinal digestion while parameters such as electrolytes, enzymes, bile, dilution, pH and time of digestion are based on available physiological data. This amended and improved digestion method (INFOGEST 2.0) avoids challenges associated with the original method, such as the inclusion of the oral phase and the use of gastric lipase. The method can be used to assess the endpoints resulting from digestion of foods by analyzing the digestion products (e.g., peptides/amino acids, fatty acids, simple sugars) and evaluating the release of micronutrients from the food matrix. The whole protocol can be completed in ~7 d, including ~5 d required for the determination of enzyme activities.COST action FA1005 INFOGEST (http://www.cost-infogest.eu/ ) is acknowledged for providing funding for travel, meetings and conferences (2011-2015). The French National Institute for Agricultural Research (INRA, www.inra.fr) is acknowledged for their continuous support of the INFOGEST network by organising and co-funding the International Conference on Food Digestion and workgroup meeting

Digestion of in duodenum cannulated pigs. Correlation between in vitro simulated gastric digestion and in vivo data

International audienceCorrelation and validation of the results of simulated gastrointestinal digestion of food compounds towards in vivo data is essential. The objective of this work was to monitor the digestion of milk micellar casein in the porcine upper intestinal tract and to match the outcome with the gastric in vitro digestion following the Infogest harmonized protocol. In pig duodenum, small amounts of intact caseins were present in all samples, while caseins were observed up to 60 min of gastric in vitro digestion. The peptide profile generated after in vitro and in vivo digestion showed clear similarities with specific overrepresented regions rich in proline and other hydrophobic residues. The statistical comparison of the in vivo and in vitro peptidome resulted in satisfactory correlation coefficients, up to 0.8. Therefore, the in vitro protocol used was a robust and simple model that provides a similar peptide profile than that found in porcine duodenum

Análisis de la actividad realizada por hospitales concertados 2006-2008

En port.: Dirección General de Financiación, Planificación e Infraestructuras. Servicio de Conciertos SanitariosYesEn este libro presentamos la información más relevante realizada durante el período de tres años, desde el 2006 hasta 2008, de forma que nos permita visualizar mejor la actividad, las tendencias y los resultados obtenidos por los Hospitales Concertados en relación con los objetivos propuestos en cada uno de los centros por los pliegos de condiciones técnicas subscritos

Análisis de la actividad realizada por hospitales concertados 2005 - 2007

En port.: Dirección General de Financiación, Planificación e Infraestructuras. Servicio de Conciertos SanitariosLibro y tablasYesEn este libro se presenta la información más relevante realizada por los hospitales concertados durante el período de tres años, desde el 2005 hasta 2007, de forma que permita visualizar mejor la actividad realizada y los resultados obtenidos por ellos en relación con los objetivos propuestos en cada uno de los centros. en la actividad registrada en 2007, se ha incluido el análisis con perspectiva de género, estimando en cada uno de los indicadores los porcentajes de hombres y mujeres asistidos o intervenidos

Memoria de la actividad de hospitales concertados de Andalucía 2005 - 2009

YesMemoria sobre los datos de la actividad hospitalaria concertada en Andalucía en los años 2005-2009, agregados por Andalucía, por provincia y por cada uno de los hospitales concertados. La publicación de estos datos sirve a las Unidades de Gestión Provincial y a los gestores de los hospitales concertados, para mejorar la planificación y gestión de los centros