477 research outputs found
Analisis Karakter Tokoh Utama Dalam Novel Lolita Karya Vladimir Nabokov
The research is entitled âAnalisis Karakter Tokoh Utama dalam Novel Lolita Karya Vladimir Nabokovâ is a skripsi which is to fulfill of the requirements to achieve the title of Sarjana Sastra. There are two problems to answer, those are : âwhat are the main charactes of Humbert Humbert described in the novel and what are the factors which affect the development of the main character Humbert Humbert. The writer has focused on the dialog through the characters and narrator's description of the action in the narrative of the story. The writer used the theory of Robert's (1983) about character. In identifying and analyzing the character the writer used the theory of Welleck and Warren (1976) to describe the leading factors development of the main character. The writer also used the intrinsic approach to analyze the interrelation between the characters in the characters in the novel that is to evaluated the characters by his words, what he is thinking and doing, and from what is the author said about them. The result of this research shows that the main character has several unique characters namely imajinative, polite, posesive, clever, calm, and economical. It also shows development of the main character in the novel that is influenced by the main character's inner factors (past, self-control, love) and the outer factors (informations and books)
Co-creativity, well-being and agency: a case study analysis of a co-creative arts group for people with dementia
At the heart of this paper is an exploration of artistic co-creativity involving people with dementia and their partners. Co-creativity promotes a relational approach to creativity which nurtures inclusion and participation. This paper investigates how co-creativity can affect well-being from the perspectives of people with dementia and their carers; and explores how well-being and agency might be usefully reconsidered. The article draws on findings from a small-scale study âWith Allâ that focused on music and dance as non-verbal and therefore inclusive artforms. A range of disciplinary perspectives, from psychology, philosophy and social sciences, inform the study.
The research used an intrinsic case-study methodology and within this a mixed-methods approach was adopted. This included dialogic interviews, video data analysis and the Canterbury Well-being Scale (CWS). Thematic analysis of the interviews and video data revealed three key themes: autonomy, connections, and art as an enabler. These themes captured the experiences of the participants and facilitated a more nuanced understanding of wellbeing and agency in the context of living with dementia. The analysis of the CWS indicated some improvements in well-being. Following this analysis using multiple data sources, the paper argues that wellbeing and agency are best understood as relational, and ongoing, rather than completed states. Further both wellbeing and agency contain their opposites (ill-being and passivity).
This innovative exploration highlighted the importance of co-creative collaboration as a method that was considered valuable by participants, and that therefore should be further considered in future research with people living with dementia
Development of a Cost-Effective Concrete Bridge Deck Preservation Program: Volume 2âFinal Results and Recommendations
The deterioration of bridge decks has been identified as a major problem in Indiana. The primary cause of this deterioration is salt water ingress from the application of deicing salts during the winter. Deicing chemicals placed on the road mix with water and enter the deck through cracks and the pore structure of the concrete. This results in corrosion of the reinforcing steel and scaling of the surface, which leads to a shortened bridge deck life and costly deck replacement. The objective of this study is to investigate potentially effective and economic bridge deck preservation methods to significantly extend the service life of bridge decks, and as a result, extend the life of bridge structures in the State of Indiana. The research is presented in two volumes. Volume 1 focuses on the development and implementation of the experimental program. A survey of State Departments of Transportation identified the types of bridge deck preservation programs that are currently in use, the methods that they have employed in the past, and the perceived level of success with these programs and methods. A literature review provided information regarding specific products that performed well, characteristics of broader chemical families and their best uses, and other variables that may influence the effectiveness of sealers. The results of the DOT survey and literature review were used to determine the materials and methods to be further investigated in the experimental study. Based on this background, a series of macrocell specimens were constructed, and a salt water exposure regimen was initiated to examine the effectiveness of deck/crack sealer materials and application methods that were identified. Volume 2 presents the results of this study which were developed through the analysis of the recorded electrical activity after 1600 days of exposure followed by autopsy of the specimens. A visual rating scheme was used to assess the specimens during autopsy and to demonstrate the correspondence between the observed severity of corrosion and the recorded electrical activity. In addition, a deck sealer was applied to specimens with preexisting corrosion to evaluate the sealer\u27s effectiveness in slowing the rate of corrosion. The deck sealer products were studied further by correlating both the sealer penetration depth and the chloride penetration profile with the products\u27 effectiveness in resisting corrosion activity. A preliminary field application of crack sealer to an existing bridge deck was completed to evaluate processes, equipment, and other required resources. Finally, recommendations are provided regarding product selection and application to enable cost effective implementation of a bridge deck sealing program across the State of Indiana
Development of a Cost-Effective Concrete Bridge Deck Preservation Program: Volume 1âDevelopment and Implementation of the Experimental Program
The deterioration of bridge decks has been identified as a major problem in Indiana. The primary cause of this deterioration is salt water ingress from the application of deicing salts during the winter. Deicing chemicals placed on the road mix with water and enter the deck through cracks and the pore structure of the concrete. This results in corrosion of the reinforcing steel and scaling of the surface, which leads to a shortened bridge deck life and costly deck replacement. The objective of this study is to investigate potentially effective and economic bridge deck preservation methods to significantly extend the service life of bridge decks, and as a result, extend the life of bridge structures in the State of Indiana. The research is presented in two volumes. Volume 1 focuses on the development and implementation of the experimental program. A survey of State Departments of Transportation identified the types of bridge deck preservation programs that are currently in use, the methods that they have employed in the past, and the perceived level of success with these programs and methods. A literature review provided information regarding specific products that performed well, characteristics of broader chemical families and their best uses, and other variables that may influence the effectiveness of sealers. The results of the DOT survey and literature review were used to determine the materials and methods to be further investigated in the experimental study. Based on this background, a series of macrocell specimens were constructed, and a salt water exposure regimen was initiated to examine the effectiveness of deck/crack sealer materials and application methods that were identified. Volume 2 presents the results of this study which were developed through the analysis of the recorded electrical activity after 1600 days of exposure followed by autopsy of the specimens. A visual rating scheme was used to assess the specimens during autopsy and to demonstrate the correspondence between the observed severity of corrosion and the recorded electrical activity. In addition, a deck sealer was applied to specimens with preexisting corrosion to evaluate the sealer\u27s effectiveness in slowing the rate of corrosion. The deck sealer products were studied further by correlating both the sealer penetration depth and the chloride penetration profile with the products\u27 effectiveness in resisting corrosion activity. A preliminary field application of crack sealer to an existing bridge deck was completed to evaluate processes, equipment, and other required resources. Finally, recommendations are provided regarding product selection and application to enable cost effective implementation of a bridge deck sealing program across the State of Indiana
Grief and loss in people living with dementia: a review and metasynthesis of qualitative studies
OBJECTIVES:
This review seeks to synthesise qualitative studies that focus on the experience of grief and loss in people living with dementia.
METHODS:
Included studies were quality appraised, synthesised and analysed using inductive thematic analysis.
RESULTS:
19 studies were selected for inclusion in the final review and metasynthesis, including 486 participants (115 participants living with dementia, 152 family carers, 219 professionals). Five key dimensions of grief in people living with dementia were identified during the analysis process: grieving for the person I used to be, grieving for how others see me, grieving for the person I will become, grieving for those who have died and what helps me with my grief.
CONCLUSION:
It is evident that people living with dementia can experience grief related to a range of previous, current and anticipated losses. Many of the studies included in this review did not directly include people living with dementia in their research and did not ask participants directly about their experience of grief and loss. As grief is a highly personal and individual experience, further research addressing the experience of grief that directly includes participants living with dementia is required, in order to improve awareness of grief-related needs and to develop and deliver support to meet these needs
Chemical enrichment and star formation in the Milky Way disk III. Chemodynamical constraints
In this paper, we investigate some chemokinematical properties of the Milky
Way disk, by using a sample composed by 424 late-type dwarfs. We show that the
velocity dispersion of a stellar group correlates with the age of this group,
according to a law proportional to t^0.26, where t is the age of the stellar
group. The temporal evolution of the vertex deviation is considered in detail.
It is shown that the vertex deviation does not seem to depend strongly on the
age of the stellar group. Previous studies in the literature seem to not have
found it due to the use of statistical ages for stellar groups, rather than
individual ages. The possibility to use the orbital parameters of a star to
derive information about its birthplace is investigated, and we show that the
mean galactocentric radius is likely to be the most reliable stellar birthplace
indicator. However, this information cannot be presently used to derive radial
evolutionary constraints, due to an intrinsic bias present in all samples
constructed from nearby stars. An extensive discussion of the secular and
stochastic heating mechanisms commonly invoked to explain the age-velocity
dispersion relation is presented. We suggest that the age-velocity dispersion
relation could reflect the gradual decrease in the turbulent velocity
dispersion from which disk stars form, a suggestion originally made by Tinsley
and Larson (1978) and supported by several more recent disk evolution
calculations. A test to distinguish between the two types of models using
high-redshift galaxies is proposed.Comment: 20 pages, 10 encapsulated postscript figures, LaTeX, uses Astronomy
and Astrophysics macro aa.cls, graphicx package, to be published in Astronomy
and Astrophysics (2004), Also available at:
http://www.astro.iag.usp.br/~macie
Photometric Survey of the Irregular Satellites
We present BVRI colors of 13 Jovian and 8 Saturnian irregular satellites
obtained with the 2.56m Nordic Optical Telescope on La Palma, the 6.5m Magellan
Baade Telescope on La Campanas, and the 6m MMT on Mt. Hopkins. The observations
were performed between December 2001 to March 2002. Nearly all of the known
irregular satellites can be divided into two distinct classes based on their
colors. One, the grey color class, has the similar colors to the C-type
asteroid, and the other, the light red color class, has colors similar to
P/D-type asteroids. We also find at least one object, the Jovian irregular J
XXIII Kalyke, that has colors similar to the red colored Centaurs/TNOs,
although its classification is unsecure. We also find that there is a
correlation between the physical properties and dynamical properties of the
irregular satellites. Most of the dynamical clusters have homogeneous colors,
which points to single homogeneous progenitors being cratered or fragmented as
the source of each individual cluster. The heterogeneous colored clusters are
most easily explained by assuming that there are several dynamical clusters in
the area, rather than just one.Comment: Submitted to Icarus, 43 pages including 5 figure
A mixed methods evaluation of a program exploring predeath grief and loss for carers of people with rarer dementias
Objectives: Predeath grief conceptualizes complex feelings of loss experienced for someone who is still living and is linked to poor emotional well-being. The Road Less Travelled program aimed to help carers of people with rarer dementias identify and process predeath grief. This study evaluated the feasibility, acceptability, and preliminary effectiveness of this program.
Design: Preâpost interventional mixed methods study.
Setting: Online videoconference group program for carers across the UK held in 2021.
Participants: Nine family carers of someone living with a rare form of dementia. Eight were female and one male
(mean age 58) with two facilitators.
Intervention: The Road Less Travelled is an online, facilitated, group-based program that aims to help carers of people with rarer dementias to explore and accept feelings of grief and loss. It involved six fortnightly 2-hour sessions.
Measurements: We collected measures for a range of well-being outcomes at baseline (T1), post-intervention (T2), and 3 months post-intervention (T3). We conducted interviews with participants and facilitators at T2.
Results: Participant attendance was 98% across all sessions. Findings from the semistructured interviews supported the acceptability of the program and identified improvements in carer well-being. Trends in the outcome measures suggested an improvement in quality of life and a reduction in depression.
Conclusion: The program was feasible to conduct and acceptable to participants. Qualitative reports and high attendance suggest perceived benefits to carers, including increased acceptance of grief, and support the need for a larger-scale pilot study to determine effectiveness
Genome-Wide TOP2A DNA Cleavage is Biased Toward Translocated and Highly Transcribed Loci
Type II topoisomerases orchestrate proper DNA topology, and they are the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations. Here, we develop a high-throughput sequencing technology to define TOP2 cleavage sites at single-base precision, and use the technology to characterize TOP2A cleavage genome-wide in the human K562 leukemia cell line. We find that TOP2A cleavage has functionally conserved local sequence preferences, occurs in cleavage cluster regions (CCRs), and is enriched in introns and lincRNA loci. TOP2A CCRs are biased toward the distal regions of gene bodies, and TOP2 poisons cause a proximal shift in their distribution. We find high TOP2A cleavage levels in genes involved in translocations in TOP2 poisonârelated leukemia. In addition, we find that a large proportion of genes involved in oncogenic translocations overall contain TOP2A CCRs. The TOP2A cleavage of coding and lincRNA genes is independently associated with both length and transcript abundance. Comparisons to ENCODE data reveal distinct TOP2A CCR clusters that overlap with marks of transcription, open chromatin, and enhancers. Our findings implicate TOP2A cleavage as a broad DNA damage mechanism in oncogenic translocations as well as a functional role of TOP2A cleavage in regulating transcription elongation and gene activation
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