Review or the Reviewer? Effects of Self-Congruity in Processing Online Travel Review

The self-congruity theory has often been applied in the tourism industry. Yet, it has not been used to examine consumers’ travel information processing. This study aims to explore the effects of self-congruity on consumers’ online travel review processing by integrating it with the Elaboration Likelihood Model. Results collected from a web-based survey in Singapore illustrated that self-congruity contributed significantly as a predictor of argument quality and source credibility. Particularly, reviewer-self-congruity having a strong effect on source credibility of online travel reviews. This study elucidates that Singaporean consumers are inclined to take a two-step information elaboration process: first forming self-congruence with a reviewer to achieve clearance via source credibility, before evaluating the review as useful after scrutinizing based on argument quality. This study suggests Online Travel Agents (OTAs) to provide more reviewer information or leverage on expert sources to increase confidence within consumers for positive online travel review processing

Plant Species Diversity along a Precipitation Gradient in Temperate Grasslands of China and Mongolia

Variations in species diversity can be linked to several ecological gradients (Huston 1994). Plant functional type is characterized by an adaption of plants to certain ecological conditions (Galan de Mera et al. 1999). In addition, patterns of species richness along an environmental gradient might be more interpretable by considering both species richness of different functional types and total species richness (Pausas and Austin 2001). Water availability generally signifies total precipitation available to support plant growth (Adler and Levine 2007), and its temporal distribution is the main driver of species composition and species diversity in arid and semi-arid environments (Shmida and Wilson 1985; Kutiel et al. 2000). Therefore, understanding how precipitation influences species diversity at a spatial scale will be critical for predicting the impacts of altered precipitation on vegetation patterns. This study aimed to examine the vegetation response to a spatial precipitation gradient in temperature grassland in China and Mongolia

Insights into information contained in multiplicative scatter correction parameters and the potential for estimating particle size from these parameters

This paper investigates the nature of information contained in scatter correction parameters. The study had two objectives. The first objective was to examine the nature and extent of information contained in scatter correction parameters. The second objective is to examine whether this information can be effectively extracted by proposing a method to obtain particularly the mean particle diameter from the scatter correction parameters. By using a combination of experimental data and simulated data generated using fundamental light propagation theory, a deeper and more fundamental insight of what information is removed by the multiplicative scatter correction (MSC) method is obtained. It was found that the MSC parameters are strongly influenced not only by particle size but also by particle concentration as well as refractive index of the medium. The possibility of extracting particle size information in addition to particle concentration was considered by proposing a two-step method which was tested using a 2-component and 4-component data set. This method can in principle, be used in conjunction with any scatter correction technique provided that the scatter correction parameters exhibit a systematic dependence with respect to particle size and concentration. It was found that the approach which uses the MSC parameters gave a better estimate of the particle diameter compared to using partial least squares (PLS) regression for the 2-component data. For the 4 component data it was found that PLS regression gave better results but further examination indicated this was due to chance correlations of the particle diameter with the two of the absorbing species in the mixture

A Transparent Display with Per-Pixel Color and Opacity Control

International audienceWe propose a new display system that composites matted foreground animated graphics and video, with per-pixel controllable emitted color and transparency, over real-world dynamic objects seen through a transparent display. Multiple users can participate simultaneously without any glasses, trackers, or additional devices. The current prototype is deployed as a desktop-monitor-sized transparent display box assembled from commodity hardware components with the addition of a high-frame-rate controllable diffuser

Porous Geometry Guided Micro-mechanical Environment Within Scaffolds for Cell Mechanobiology Study in Bone Tissue Engineering

Mechanobiology research is for understanding the role of mechanics in cell physiology and pathology. It will have implications for studying bone physiology and pathology and to guide the strategy for regenerating both the structural and functional features of bone. Mechanobiological studies in vitro apply a dynamic micro-mechanical environment to cells via bioreactors. Porous scaffolds are commonly used for housing the cells in a three-dimensional (3D) culturing environment. Such scaffolds usually have different pore geometries (e.g. with different pore shapes, pore dimensions and porosities). These pore geometries can affect the internal micro-mechanical environment that the cells experience when loaded in the bioreactor. Therefore, to adjust the applied micro-mechanical environment on cells, researchers can tune either the applied load and/or the design of the scaffold pore geometries. This review will provide information on how the micro-mechanical environment (e.g. fluid-induced wall shear stress and mechanical strain) is affected by various scaffold pore geometries within different bioreactors. It shall allow researchers to estimate/quantify the micro-mechanical environment according to the already known pore geometry information, or to find a suitable pore geometry according to the desirable micro-mechanical environment to be applied. Finally, as future work, artificial intelligent – assisted techniques, which can achieve an automatic design of solid porous scaffold geometry for tuning/optimising the micro-mechanical environment are suggested

Some protein interaction data do not exhibit power law statistics

It has been claimed that protein-protein interaction (PPI) networks are scale-free based on the observation that the node degree sequence follows a power law. Here we argue that these claims are likely to be based on erroneous statistical analysis. Typically, the supporting data are presented using frequency-degree plots. We show that such plots can be misleading, and should correctly be replaced by rank-degree plots. We provide two PPI network examples in which the frequency-degree plots appear linear on a log-log scale, but the rank-degree plots demonstrate that the node degree sequence is far from a power law. We conclude that at least these PPI networks are not scale-free.Comment: 4 pages, 2 figure

A twist in the tail : SHAPE mapping of long-range interactions and structural rearrangements of RNA elements involved in HCV replication

The RNA structure and long-range interactions of the SL9266 cis-acting replication element located within the NS5B coding region of hepatitis C virus (HCV) were determined using selective 2′-hydroxyl acylation analysed by primer extension. Marked differences were found in the long-range interactions of SL9266 when the two widely used genotype 2a JFH-1 (HCVcc) and genotype 1b Con1b sub-genomic replicon systems were compared. In both genomes, there was evidence for interaction of the sub-terminal bulge loop of SL9266 and sequences around nucleotide 9110, though the replication phenotype of genomes bearing mutations that disrupted this interaction was fundamentally different. In contrast, a ‘kissing loop’ interaction between the terminal loop of SL9266 and sequences in the 3′-untranslated X-tail was only detectable in JFH-1-based genomes. In the latter, where both long-range interactions are present, they were independent, implying that SL9266 forms the core of an extended pseudoknot. The presence of the ‘kissing loop’ interaction inhibited the formation of SL9571 in the 3′-X-tail, an RNA structure implicated in genome replication. We propose that, SL9266 may contribute a switch function that modulates the mutually incompatible translation and replication events that must occur for replication of the positive-strand RNA genome of HCV

A Rapid LC-MS/MS Method for Quantification of CSUOH0901, A Novel Antitumor Agent, in Rat Plasma

CSUOH0901, a novel anticancer derivative of nimesulide, exhibits very promising anticancer activities in various cancer cell lines. In order to support further pharmacological and toxicological studies of this promising anticancer drug candidate, an LC-MS/MS method was developed and validated in accordance with the US Food and Drug Administration guidelines. The drug molecules were extracted from plasma samples by protein precipitation and then analyzed with LC-ESI-MS/MS. An excellent analyte separation was achieved using a phenomenex C18 column with a mobile phase of 90% methanol and 5 m m of ammonium formate. The validated linear dynamic range was between 0.5 and 100 ng/mL and the achieved correlation coefficient (r2) was \u3e0.9996. The results of inter- and intra-day precision and accuracy were satisfactory, that is, \u3c12% for accuracy and within ±5% for precision at a low and high quality control concentrations, respectively. In addition, the analyte and internal standard (JCC76) were found to be stable under the storage conditions at −20°C for about 2 months. Hence, the acquired results proved that the LC-ESI-MS/MS method developed is precise, accurate and selective for the quantification of CSUOH0901 in plasma, and can be used for pharmacokinetic studies