61 research outputs found

    Changing Professional Identity in the Transition from Practitioner to Lecturer in Higher Education: an Interpretive Phenomenological Analysis

    Get PDF
    This research explores the experiences of five professional practitioners from disciplines including teaching, youth work, sport and health who had become lecturers in Higher Education. Their experiences are considered using Interpretative Phenomenological Analysis and tentative conclusions are reached on the meaning of such experiences for the individuals. The work extends previous studies (Shreeve 2010, 2011; Gourlay 2011a, 2011b; Boyd & Harris 2010) to consider the relationship between knowledge and influence and how institutional preference for knowledge gained from research impacts on the validity of knowledge derived from professional experience. The research finds shared feelings associated with inauthenticity and loss arising from concerns that the contribution of the professional in Higher Education is undervalued. The research challenges the assumption that professional practitioners adopt the professional identity of a lecturer in Higher Education instead finding that they create their own professional identities in the liminal space between the professional and academic domains, but points to difficulties associated with constructed nature of such professional identities within the institutional structure of a Higher Education institution

    Proteoma y vías de señalización inducidas por AAS en células que expresan el VHC

    Get PDF
    RESUMEN El AAS disminuye la expresión del VHC por mecanismos aún desconocidos. Se compararon perfiles de expresión proteómica en células de hepatocarcinoma (Huh7) y células que expresan proteínas no estructuradas del VHC (Huh7-VHC) tratadas con AAS 4mM. Los perfiles obtenidos mediante electroforesis bidimensional fueron analizados por pI y PM. Se identificaron diferentes patrones entre células Huh7- VHC tratadas y no tratadas con AAS. Entre las proteínas diferencialmente expresadas encontramos proteínas relacionadas con proliferación celular (MTMR6, FAM22, HDGF y HCF-1) y sobreexpresión de angiotensina, PI4KA y STAT-1. A las 72h, identificamos sobreexpresión de adenil-succinato sintasa, 2’-3’-di-deoxiadenosina, proteína ligasa de ubiquitina E6A, adenilsuccinato-liasa y nibrina. El AAS induce diferentes patrones proteicos en células Huh7- VHC, promoviendo la activación de proteínas relacionadas con progresión celular, reparación de DNA, inhibición de apoptosis y estimulación del crecimiento. ABSTRACT ASA has been shown to downregulate HCV expression; however, the involved mechanisms are unknown. We used proteomic analysis to compare protein expression profiles between human hepatocarcinome cells (Huh7) and Huh7-HCV cells harboring expression of non-structural HCV proteins to elucidate the mechanisms involved in ASAmediated downregulation of HCV replication. Cell lines were treated with 4 mM ASA and harvested to isolate total proteins, which were resolved by 2-DE. Gels were analyzed and proteins elucidated by pI and MW patterns. Different protein patterns among hepatocytes expressing HCV-proteins in ASA treated and untreated cells were found. Among proteins differentially expressed we found proteins related to cellular proliferation (MTMR6, FAM22, HDGF y HCF-1) and overexpression of angiotensin (PI4KA y STAT-1). We found that ASA induces different protein patterns in Huh7-HCV cells promoting activation of proteins involved in cell progression, repair of double strand breaks, proliferation, inhibition of apoptosis and growth stimulation at the same time that it decreased HCV expression

    Distribución y abundancia de meiobentos en tres estanques de cultivo de penaeus vannamei en camaronera

    Get PDF
    El meiobentos es un importante grupo sistémico y ecológico de organismos que viven en el fondo de  ambientes acuáticos.  En  una  camaronera  industrial  en  el  estuario  del  río  Portoviejo  (provincia de  Manabí,  Ecuador) durante un  ciclo  de  cultivo  de  camarón  en  ambientes  de  estanques  fueron encontrados 12 taxones de la meiofauna, de los que se analizaron cuatro grupos: Nematoda (63%), Copépoda  (13%),  huevos  de  invertebrados (7%)  y  Ostracoda (4%).  Se  analizaron  los  factores físico-químicos  de  la  meiofauna:  temperatura,  salinidad,  pH, oxígeno  disuelto, materia  orgánica  y granulometría  en  3  estanques  de  camarón,  considerando  6  estaciones  de muestreo  en  cada uno de ellos, durante un ciclo de cultivo. Se registró una variación del meiobentos en los estratos 0-5 cm y 5-10 cm influenciada por los parámetros ambientales, afectado por el secado de los estanques y el ingreso de agua. El factor determinante que influye en la diversidad del meiobentos es el tipo de sedimento y su característica granulométrica, observándose que en sedimento fino los organismos tienden a ocupar el estrato superior. Palabras clave: Factores ambientales; macrobentos; microbentos; meiofauna; nematoda, granulometrí

    Unexpected reactivity of “GaI” towards N,N′-diaryl-β-diketiminate tin(II) chloride: Synthesis, X-ray diffraction analysis and DFT studies

    Get PDF
    Reaction of the [HC(CMeNAr)2]SnCl (Ar = 2,4,6-Me3C6H2) with ‘‘GaI” in THF provided an unexpected transhalogenation reaction product [HC(CMeNAr)2]SnI. The crystal structure shows a tin(II) ion with a distorted tetrahedral pyramidal geometry. Theoretical calculations, using density functional theory (B3LYP), suggest the probable reaction mechanism for transhalogenation. The activation energy for moving from reactant ([HC(CMeNAr)2]SnCl to product [HC (CMeNAr)2]SnI) is only 10.2 kcal/mol. The chloride ion is displaced by the iodine ion, probably by the help of the gallium atom when it is coordinated to the chlorine atom

    Measuring personal networks and their relationship with scientific production

    Get PDF
    The analysis of social networks has remained a crucial and yet understudied aspect of the efforts to measure Triple Helix linkages. The Triple Helix model aims to explain, among other aspects of knowledge-based societies, ¿the current research system in its social context. This paper develops a novel approach to study the research system from the perspective of the individual, through the analysis of the relationships among researchers, and between them and other social actors. We develop a new set of techniques and show how they can be applied to the study of a specific case (a group of academics within a university department). We analyse their informal social networks and show how a relationship exists between the characteristics of an individual¿s network of social links and his or her research output

    Networking strategies for minority managers

    No full text

    Authentic leadership

    No full text
    corecore