121 research outputs found

    Korzyści z podejmowania regularnej aktywności fizycznej przez osoby starsze = The benefits of regular physical activity for the elderly

    Get PDF
    Kaźmierczak U., Radzimińska A., Dzierżanowski M., Bułatowicz I., Strojek K., Srokowski G., Zukow W. Korzyści z podejmowania regularnej aktywności fizycznej przez osoby starsze = The benefits of regular physical activity for the elderly. Journal of Education, Health and Sport. 2015;5(1):56-68. ISSN 2391-8306. DOI: 10.5281/zenodo.13935http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%281%29%3A56-68https://pbn.nauka.gov.pl/works/524287http://dx.doi.org/10.5281/zenodo.13935Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja.Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 15.06.2014. Revised 05.10.2014. Accepted: 25.12.2014. Korzyści z podejmowania regularnej aktywności fizycznej przez osoby starszeThe benefits of regular physical activity for the elderly Kaźmierczak U.¹, Radzimińska A.¹, Dzierżanowski M.², Bułatowicz I.¹, Strojek K.¹, Srokowski G.¹, Zukow W.³ Katedra Fizjoterapii CM UMK w Toruniu1Zakład Kinezyterapii i Masażu Leczniczego UMK CM w Toruniu²Zakład Terapii Manualnej UMK CM w Toruniu3Wydział Kultury Fizycznej, Zdrowia i Turystyki, Uniwersytet Kazimierza Wielkiego w Bydgoszczy Słowa kluczowe: regularna aktywność fizyczna, osoby starsze. Keywords: regular physical activity, elderly. AbstraktW państwach rozwiniętych i rozwijających się coraz większą grupę społeczeństw stanowią seniorzy.Świadomość problemu spowodowała podjęcie powszechnej dyskusji ekspertów i praktyków z dziedzin medycznych na temat konieczności działań niezbędnych dla zapewnienia społeczeństwom pomyślnej starości.Od dawna wskazuje się, że brak aktywności ruchowej jest dla zdrowia niebezpieczny.Starzeniu się układu sercowo-naczyniowego towarzyszy dużo niekorzystnych zmian strukturalnych, czynnościowych i biochemicznych. Za typowe dla tego okresu zmiany uważa się osłabienie możliwości relaksacji włókien mięśniowych, co może być przyczyną rozkurczowej niewydolności serca.Trening zdrowotny – jest rodzajem aktywności fizycznej wykonywanej z powodów medycznych. Celem jest uzyskanie efektów fizycznych oraz psychicznych przeciwdziałających zmniejszaniu się zdolności adaptacyjnych organizmu.Eksperci przekonują osoby starsze o korzyściach płynących z aktywnego fizycznie stylu życia. Bogate piśmiennictwo poruszające tematykę medycznych aspektów procesu starzenia, mówi o niezaprzeczalnym znaczeniu ruchu dla toczących się w ludzkim ciele procesów inwolucyjnych. Aktywność fizyczna odpowiednio dozowana jest w stanie wyraźnie zmniejszyć negatywny wpływ tych zmian i jak najdłużej pozwolić utrzymać zdrowie fizyczne, psychiczne i społeczne. Zauważono, że systematycznie dozowany wysiłek fizyczny zmniejsza ryzyko wystąpienia wielu chorób np. cukrzycy, miażdżycy, choroby niedokrwiennej serca.Liczne badania naukowe i bogate piśmiennictwo gerontologiczne przedstawiają najnowsze doniesienia specjalistów o tym, jak należy prawidłowo przygotować i prowadzić trening fizyczny z osobami starszymi. Ludzki organizm zaczyna starzeć się około 20-25 roku życia. Zmiany dotyczą wszystkich układów ciała. Najbardziej odczuwalne w życiu codziennym są te, które zachodzą w układzie krążeniowo-oddechowym i mięśniowo-szkieletowym. Trening fizyczny dla osoby starszej, aby był skuteczny i bezpieczny, powinien być skonstruowany i nadzorowany przez specjalistę. AbstractIn developed and developing countries an increasing group of societies are seniors. Awareness of the problem has led to widespread discussion of experts and practitioners from the fields of medical devices on the need for the measures necessary to ensure that societies successful old age. For a long time, indicates that the lack of motor activity is dangerous to health. Aging of the cardiovascular system is accompanied by a lot of adverse structural changes and biochemical function.For typical of this period of change is believed to be weakening the possibility of relaxation of the muscle fibers, which may cause diastolic heart failure. Training of health-is a type of physical activity performed for medical reasons. The goal is to get mental and physical effects against reducing the adaptability of the body. Experts are finding older people about the benefits of a physically active lifestyle. Rich writing evocative theme of medical aspects of the aging process, speaks of undeniable importance for traffic in human flesh involutional processes. Physical activity appropriately dosed is able to clearly reduce the negative impact of these changes and as long as you can afford to maintain the physical, mental and social health. It was noted that systematically dosed exercise reduces the risk of many diseases, eg. diabetes mellitus, atherosclerosis, coronary heart disease.Numerous scientific studies and extensive external links gerontologiczne submit the latest reports of professionals about how to properly prepare and conduct physical training with the elderly. The human body begins to age about 20-25 years of age. The changes apply to all body systems. Most felt in everyday life are the ones that occur in the breathing cardiopulmonary and musculo-skeletal. Physical training for older persons, in order to be effective and safe, should be designed and supervised by a specialist

    Structure effects in Ne-20+Pb-208 quasi-elastic scattering

    Get PDF
    Preliminary results of an analysis of experiments devoted to a study of the sensitivity of the 20Ne + 208Pb quasi-elastic angular distributions at two near-barrier energies and the previously measured corresponding barrier distribution to the value of the nuclear quadrupole deformation length of 20Ne are reported

    Are the weak channels really weak?

    Get PDF
    The transfer probabilities for 20Ne + 90Zr and 20Ne + 92Zr at energies near the Coulomb barrier were measured. This quantity turned out to be very similar for both Zr isotopes and does not explain the observed differences in the barrier height distributions for these systems

    Near barrier scattering of 8He on 208Pb

    Get PDF
    The exotic nucleus 8He is investigated by means of the measurement of the angular distributions of the elastic channel and the 6He and 4He fragment yields produced in the collision with a 208Pb target at two energies around the Coulomb barrier, 16 and 22 MeV. The experiment was performed at the GANIL-SPIRAL facility, with the aim of extracting information about the structure of 8He and the relevant reaction mechanisms. In this contribution, details of the experimental setup and preliminary data on elastic cross sections are reported

    Laser excitation of the n=3 level of positronium for antihydrogen production

    Get PDF
    We demonstrate the laser excitation of the n = 3 state of positronium (Ps) in vacuum. A combination of a specially designed pulsed slow positron beam and a high-efficiency converter target was used to produce Ps. Its annihilation was recorded by single-shot positronium annihilation lifetime spectroscopy. Pulsed laser excitation of the n = 3 level at a wavelength lambda approximate to 205 nm was monitored via Ps photoionization induced by a second intense laser pulse at lambda = 1064 nm. About 15% of the overall positronium emitted into vacuum was excited to n = 3 and photoionized. Saturation of both the n = 3 excitation and the following photoionization was observed and explained by a simple rate equation model. The positronium's transverse temperature was extracted by measuring the width of the Doppler-broadened absorption line. Moreover, excitation to Rydberg states n = 15 and 16 using n = 3 as the intermediate level was observed, giving an independent confirmation of excitation to the 3 P-3 state

    A role for NPY-NPY2R signaling in albuminuric kidney disease

    Get PDF
    Albuminuria is an independent risk factor for the progression to end-stage kidney failure, cardiovascular morbidity, and premature death. As such, discovering signaling pathways that modulate albuminuria is desirable. Here, we studied the transcriptomes of podocytes, key cells in the prevention of albuminuria, under diabetic conditions. We found that Neuropeptide Y (NPY) was significantly down-regulated in insulin-resistant vs. insulin-sensitive mouse podocytes and in human glomeruli of patients with early and late-stage diabetic nephropathy, as well as other nondiabetic glomerular diseases. This contrasts with the increased plasma and urinary levels of NPY that are observed in such conditions. Studying NPY-knockout mice, we found that NPY deficiency in vivo surprisingly reduced the level of albuminuria and podocyte injury in models of both diabetic and nondiabetic kidney disease. In vitro, podocyte NPY signaling occurred via the NPY2 receptor (NPY2R), stimulating PI3K, MAPK, and NFAT activation. Additional unbiased proteomic analysis revealed that glomerular NPY-NPY2R signaling predicted nephrotoxicity, modulated RNA processing, and inhibited cell migration. Furthermore, pharmacologically inhibiting the NPY2R in vivo significantly reduced albuminuria in adriamycin-treated glomerulosclerotic mice. Our findings suggest a pathogenic role of excessive NPY-NPY2R signaling in the glomerulus and that inhibiting NPY-NPY2R signaling in albuminuric kidney disease has therapeutic potential. Chronic kidney disease (CKD) is a major global healthcare concern, affecting over 10% of the general population, and frequently occurs secondary to other systemic disorders including diabetes, obesity, hypertension, and the metabolic syndrome. A common early hallmark of CKD is albuminuria, which not only reflects damage to the glomerular filtration barrier (GFB) in the kidney but also is an important independent risk factor for the progression to end-stage renal failure and cardiovascular disease (1⇓–3). Thus, strategies to prevent albuminuria have important therapeutic potential, particularly in the early stages of CKD progression. Podocytes are highly specialized epithelial cells of the glomerulus, lining the urinary side of the filtration barrier. Owing to their complex, dynamic structures and their ability to secrete (and adapt to) a number of growth factors, these cells have a central role in filtration barrier maintenance (4). As such, podocyte damage is a key driver of albuminuria and glomerular disease in numerous settings and occurs early in the pathogenesis of many albuminuric conditions (5⇓⇓⇓–9). While it is well-established that podocyte damage is a major cause of albuminuria (8), the pathways and molecules involved in podocyte injury are incompletely understood. We (10, 11) and others (12, 13) have highlighted the importance of podocyte insulin responses in maintaining glomerular function, and it is now evident that circulating factors associated with common systemic disorders, including diabetes, obesity, and the metabolic syndrome, can directly induce podocyte insulin resistance (14⇓⇓–17) and associated damage (15, 18). In this study, we analyzed the transcriptomes of insulin-sensitive and insulin-resistant podocytes with the aim of identifying molecules that are differentially regulated in podocyte damage, which may play a role in albuminuric kidney disease. This unbiased transcriptome analysis revealed that Neuropeptide Y (Npy) was the most highly down-regulated transcript in insulin-resistant vs. insulin-sensitive podocytes. Analysis of patient cohorts also revealed a significant reduction in glomerular NPY expression in both early and late-stage diabetic nephropathy (DN), as well as in several other human albuminuric conditions. This contrasts with the increased plasma and urinary levels of NPY that are observed in diabetes and CKD (19⇓⇓–22). This prompted us to further investigate the potential role of NPY (and NPY signaling) in the podocyte and glomerulus

    Particle tracking at cryogenic temperatures: the Fast Annihilation Cryogenic Tracking (FACT) detector for the AEgIS antimatter gravity experiment

    Get PDF
    The AEgIS experiment is an interdisciplinary collaboration between atomic, plasma and particle physicists, with the scientific goal of performing the first precision measurement of the Earth’s gravitational acceleration on antimatter. The principle of the experiment is as follows: cold antihydrogen atoms are synthesized in a Penning-Malmberg trap and are Stark accelerated towards a moire deflectometer, the classical counterpart of an atom interferometer, and annihilate on a position sensitive detector. Crucial to the success of the experiment is an antihydrogen detector that will be used to demonstrate the production of antihydrogen and also to measure the temperature of the anti-atoms and the creation of a beam. The operating requirements for the detector are very challenging: it must operate at close to 4 K inside a 1 T solenoid magnetic field and identify the annihilation of the antihydrogen atoms that are produced during the 1 µs period of antihydrogen production. Our solution — called the FACT detector — is based on a novel multi-layer scintillating fiber tracker with SiPM readout and off the shelf FPGA based readout system. This talk will present the design of the FACT detector and detail the operation of the detector in the context of the AEgIS experiment
    corecore