Urban Extension\u27s New Nontraditional Offering: Parent-Child Reading Enhancement Program

Urbanization is causing a major shift in Extension\u27s programming throughout the United States. We present results of a nontraditional urban program (the Parent-Child Reading Enhancement Program) that is being implemented by Alabama Cooperative Extension System\u27s Urban Affairs and New Nontraditional Programs unit. Findings suggest that this Extension program is successful in increasing urban parents\u27 knowledge and skills related to enhancing their children\u27s reading ability. Implications for urban Extension are discussed

Integrated Systems Design of a Cargo Aircraft with Environmentally Responsible Goals

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97068/1/AIAA2012-1759.pd

The Grizzly, October 2, 2008

Lighting Up Laws: New Smoking Policies on College Campuses • Sexual Perversity Comes to Ursinus • Water, Water Everywhere • Users to Delete Profiles? Student Reactions to New Facebook • U.S. Credit Crisis Hits Home for Some Ursinus Students • College Students Hurt by Economic Woes • Banned Books Week • Lethal Filler Found in Chinese Dairy • Texting Responsible for Train Crash? • Hispania Dances Their Hearts Out for an Ursinus Audience • Tribute to Sub Connection Employee Patro • A Look Into the Past with the Sophomore Class President • Women in Science: Progress in the Scientific Community • Kabuki Dancer to Choreograph at UC • College Students Targets for ID Theft • Opinions: Presidential Debate 2008: The Battle in Mississippi; Open Your Eyes to the Truth About Senator Barack Obama; Political Messages Overtake Television More Than Ever • Cross Country Senior Spotlight: Christa Johnson • Cosmic Sucker Punch: UC Ultimate Frisbee Scores • Could New Turf Field be the Key to Football\u27s Future Success?https://digitalcommons.ursinus.edu/grizzlynews/1770/thumbnail.jp

Matricellular protein CCN3 mitigates abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is a major cause of morbidity and mortality; however, the mechanisms that are involved in disease initiation and progression are incompletely understood. Extracellular matrix proteins play an integral role in modulating vascular homeostasis in health and disease. Here, we determined that the expression of the matricellular protein CCN3 is strongly reduced in rodent AAA models, including angiotensin II-induced AAA and elastase perfusion-stimulated AAA. CCN3 levels were also reduced in human AAA biopsies compared with those in controls. In murine models of induced AAA, germline deletion of Ccn3 resulted in severe phenotypes characterized by elastin fragmentation, vessel dilation, vascular inflammation, dissection, heightened ROS generation, and smooth muscle cell loss. Conversely, overexpression of CCN3 mitigated both elastase- and angiotensin II-induced AAA formation in mice. BM transplantation experiments suggested that the AAA phenotype of CCN3-deficient mice is intrinsic to the vasculature, as AAA was not exacerbated in WT animals that received CCN3-deficient BM and WT BM did not reduce AAA severity in CCN3-deficient mice. Genetic and pharmacological approaches implicated the ERK1/2 pathway as a critical regulator of CCN3-dependent AAA development. Together, these results demonstrate that CCN3 is a nodal regulator in AAA biology and identify CCN3 as a potential therapeutic target for vascular disease

Changing behaviour: Increasing the effectiveness of workplace interventions in creating pro-environmental behaviour change

There is a great deal of research outlining interventions to increase pro-environmental behaviour, many of which are aimed at employees. However, to date the results for these have not lived up to their initial promise. Instead of offering another intervention, we propose a model which identifies psychological conditions under which these interventions are most likely to succeed. Through the integration of previously separate literatures from experimental social psychology, organisational psychology, organisational behaviour and environmental psychology, we suggest that the degree to which the intervention-related goal is efficacious and attractive, self-concordant, in conflict with other goals, and perceived to be completed will affect the level and type of behaviour change. Our model aims to provide actionable knowledge that extends our understanding of the effectiveness of workplace interventions designed to increase green organisational behaviour

Ensembl Genomes 2016: more genomes, more complexity

Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of programmatic and interactive interfaces to a rich range of data including reference sequence, gene models, transcriptional data, genetic variation and comparative analysis. This paper provides an update to the previous publications about the resource, with a focus on recent developments. These include the development of new analyses and views to represent polyploid genomes (of which bread wheat is the primary exemplar); and the continued up-scaling of the resource, which now includes over 23 000 bacterial genomes, 400 fungal genomes and 100 protist genomes, in addition to 55 genomes from invertebrate metazoa and 39 genomes from plants. This dramatic increase in the number of included genomes is one part of a broader effort to automate the integration of archival data (genome sequence, but also associated RNA sequence data and variant calls) within the context of reference genomes and make it available through the Ensembl user interfaces

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

BACKGROUND: Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes. METHODS: We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization. RESULTS: During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events. CONCLUSIONS: Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)

EUCOM NPS GRADS

A list in Excel format of International student thesis work at the Naval Postgraduate School, 1995-2011, by region. Data was contributed to Partnership for Peace Training and Education Center (PPTEC) Program by NPS's Dudley Knox Library from records in the NPS Archive, Calhoun (http://calhoun.nps.edu), including Year of completion, Country, Branch (of Service), Thesis Title, Abstract, Degree received and a link to the thesis in the NPS Archive: Cahoun. This list in spreadsheet format was compiled by Partnership for Peace Training and Education Center's Brandon Humphries. This spreadsheet is published as received; please use advisedly

CENTCOM NPS GRADS

A list in Excel format of International student thesis work at the Naval Postgraduate School, 1995-2011, by region. Data was contributed to Partnership for Peace Training and Education Center (PPTEC) Program by NPS's Dudley Knox Library from records in the NPS Archive, Calhoun (http://calhoun.nps.edu), including Year of completion, Country, Branch (of Service), Thesis Title, Abstract, Degree received and a link to the thesis in the NPS Archive: Cahoun. This list in spreadsheet format was compiled by Partnership for Peace Training and Education Center's Brandon Humphries. This spreadsheet is published as received; please use advisedly

SOUTHCOM NPS GRADS

A list in Excel format of International student thesis work at the Naval Postgraduate School, 1995-2011, by region. Data was contributed to Partnership for Peace Training and Education Center (PPTEC) Program by NPS's Dudley Knox Library from records in the NPS Archive, Calhoun (http://calhoun.nps.edu), including Year of completion, Country, Branch (of Service), Thesis Title, Abstract, Degree received and a link to the thesis in the NPS Archive: Cahoun. This list in spreadsheet format was compiled by Partnership for Peace Training and Education Center's Brandon Humphries. This spreadsheet is published as received; please use advisedly