107 research outputs found
Emergence of Complex Spatio-Temporal Behavior in Nonlinear Field Theories
We investigate the emergence of time-dependent nonperturbative configurations
during the evolution of nonlinear scalar field models with symmetric and
asymmetric double-well potentials. Complex spatio-temporal behavior emerges as
the system seeks to establish equipartition after a fast quench. We show that
fast quenches may dramatically modify the decay rate of metastable states in
first order phase transitions. We briefly suggest possible applications
incondensed matter systems and early universe cosmology.Comment: 6 pages, 8 figure
Resonant emergence of global and local spatiotemporal order in a nonlinear field model
We investigate the nonequilibrium evolution of a scalar field in (2+1)
dimensions. The field is set in a double-well potential in contact (open) or
not (closed) with a heat bath. For closed systems, we observe the synchronized
emergence of coherent spatiotemporal configurations, identified with oscillons.
This initial global ordering degenerates into localized order until all
oscillons disappear. We show that the synchronization is driven by resonant
parametric oscillations of the field's zero mode and that local ordering is
only possible outside equipartition. None of these orderings occur for open
systems.Comment: 4 pages, 5 figures, LaTeX, minor corrections to eqs. 1,3,
Pair distribution function and structure factor of spherical particles
The availability of neutron spallation-source instruments that provide total
scattering powder diffraction has led to an increased application of real-space
structure analysis using the pair distribution function. Currently, the
analytical treatment of finite size effects within pair distribution refinement
procedures is limited. To that end, an envelope function is derived which
transforms the pair distribution function of an infinite solid into that of a
spherical particle with the same crystal structure. Distributions of particle
sizes are then considered, and the associated envelope function is used to
predict the particle size distribution of an experimental sample of gold
nanoparticles from its pair distribution function alone. Finally, complementing
the wealth of existing diffraction analysis, the peak broadening for the
structure factor of spherical particles, expressed as a convolution derived
from the envelope functions, is calculated exactly for all particle size
distributions considered, and peak maxima, offsets, and asymmetries are
discussed.Comment: 7 pages, 6 figure
Resonant nucleation of spatio-temporal order via parametric modal amplification
We investigate, analytically and numerically, the emergence of
spatio-temporal order in nonequilibrium scalar field theories. The onset of
order is triggered by destabilizing interactions (DIs), which instantaneously
change the interacting potential from a single to a double-well, tunable to be
either degenerate (SDW) or nondegenerate (ADW). For the SDW case, we observe
the emergence of spatio-temporal coherent structures known as oscillons. We
show that this emergence is initially synchronized, the result of parametric
amplification of the relevant oscillon modes. We also discuss how these ordered
structures act as bottlenecks for equipartition. For ADW potentials, we show
how the same parametric amplification mechanism may trigger the rapid decay of
a metastable state. For a range of temperatures, the decay rates associated
with this resonant nucleation can be orders of magnitude larger than those
computed by homogeneous nucleation, with time-scales given by a simple power
law, , where depends weakly on the
temperature and is the free-energy barrier of a critical
fluctuation.Comment: 38 pages, 20 figures now included within the tex
Nonequilibrium Precursor Model for the Onset of Percolation in a Two-Phase System
Using a Boltzmann equation, we investigate the nonequilibrium dynamics of
nonperturbative fluctuations within the context of Ginzburg-Landau models. As
an illustration, we examine how a two-phase system initially prepared in a
homogeneous, low-temperature phase becomes populated by precursors of the
opposite phase as the temperature is increased. We compute the critical value
of the order parameter for the onset of percolation, which signals the
breakdown of the conventional dilute gas approximation.Comment: 4 pages, 4 eps figures (uses epsf), Revtex. Replaced with version in
press Physical Review
Cognitive impairment induced by delta9-tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors
Delta-9-tetrahydrocannabinol (THC), the main psychoactive compound of marijuana, induces numerous undesirable effects, including memory impairments, anxiety, and dependence. Conversely, THC also has potentially therapeutic effects, including analgesia, muscle relaxation, and neuroprotection. However, the mechanisms that dissociate these responses are still not known. Using mice lacking the serotonin receptor 5-HT2A, we revealed that the analgesic and amnesic effects of THC are independent of each other: while amnesia induced by THC disappears in the mutant mice, THC can still promote analgesia in these animals. In subsequent molecular studies, we showed that in specific brain regions involved in memory formation, the receptors for THC and the 5-HT2A receptors work together by physically interacting with each other. Experimentally interfering with this interaction prevented the memory deficits induced by THC, but not its analgesic properties. Our results highlight a novel mechanism by which the beneficial analgesic properties of THC can be dissociated from its cognitive side effects
Establishing a core outcome set for peritoneal dialysis : report of the SONG-PD (standardized outcomes in nephrology-peritoneal dialysis) consensus workshop
Outcomes reported in randomized controlled trials in peritoneal dialysis (PD) are diverse, are measured inconsistently, and may not be important to patients, families, and clinicians. The Standardized Outcomes in Nephrology-Peritoneal Dialysis (SONG-PD) initiative aims to establish a core outcome set for trials in PD based on the shared priorities of all stakeholders. We convened an international SONG-PD stakeholder consensus workshop in May 2018 in Vancouver, Canada. Nineteen patients/caregivers and 51 health professionals attended. Participants discussed core outcome domains and implementation in trials in PD. Four themes relating to the formation of core outcome domains were identified: life participation as a main goal of PD, impact of fatigue, empowerment for preparation and planning, and separation of contributing factors from core factors. Considerations for implementation were identified: standardizing patient-reported outcomes, requiring a validated and feasible measure, simplicity of binary outcomes, responsiveness to interventions, and using positive terminology. All stakeholders supported inclusion of PD-related infection, cardiovascular disease, mortality, technique survival, and life participation as the core outcome domains for PD
TOI-431/HIP 26013: A super-Earth and a sub-Neptune transiting a bright, early K dwarf, with a third RV planet
We present the bright (Vmag = 9.12), multiplanet system TOI-431, characterized with photometry and radial velocities (RVs). We estimate the stellar rotation period to be 30.5 ± 0.7 d using archival photometry and RVs. Transiting Exoplanet Survey Satellite (TESS) objects of Interest (TOI)-431 b is a super-Earth with a period of 0.49 d, a radius of 1.28 ± 0.04 R, a mass of 3.07 ± 0.35 M, and a density of 8.0 ± 1.0 g cm-3; TOI-431 d is a sub-Neptune with a period of 12.46 d, a radius of 3.29 ± 0.09 R, a mass of 9.90+1.53-1.49 M, and a density of 1.36 ± 0.25 g cm-3. We find a third planet, TOI-431 c, in the High Accuracy Radial velocity Planet Searcher RV data, but it is not seen to transit in the TESS light curves. It has an Msin i of 2.83+0.41-0.34 M, and a period of 4.85 d. TOI-431 d likely has an extended atmosphere and is one of the most well-suited TESS discoveries for atmospheric characterization, while the super-Earth TOI-431 b may be a stripped core. These planets straddle the radius gap, presenting an interesting case-study for atmospheric evolution, and TOI-431 b is a prime TESS discovery for the study of rocky planet phase curves.Fil: Osborn, Ares. University of Warwick; Reino UnidoFil: Armstrong, David J. University of Warwick; Reino UnidoFil: Cale, Bryson. George Mason University; Estados UnidosFil: Brahm, Rafael. Universidad Adolfo Ibañez; Chile. Instituto de AstrofÃsica; ChileFil: Wittenmyer, Robert A. University Of Southern Queensland; AustraliaFil: Dai, Fei. Division Of Geological And Planetary Sciences; Estados UnidosFil: Crossfield, Ian J. M. University of Kansas; Estados UnidosFil: Bryant, Edward M. University of Warwick; Reino UnidoFil: Adibekyan, Vardan. Universidad de Porto; PortugalFil: Cloutier, Ryan. Harvard-Smithsonian Center for Astrophysics; Estados UnidosFil: Collins, Karen A. Harvard-Smithsonian Center for Astrophysics; Estados UnidosFil: Delgado Mena, E.. Universidad de Porto; PortugalFil: Fridlund, Malcolm. Leiden University; PaÃses Bajos. Chalmers University of Technology; SueciaFil: Hellier, Coel. Keele University; Reino UnidoFil: Howell, Steve B. NASA Ames Research Center; Estados UnidosFil: King, George W. University of Warwick; Reino UnidoFil: Lillo Box, Jorge. Consejo Superior de Investigaciones CientÃficas. Centro de AstrobiologÃa; EspañaFil: Otegi, Jon. Universidad de Ginebra; Suiza. Universitat Zurich; SuizaFil: Sousa, S.. Universidad de Porto; PortugalFil: Stassun, Keivan G. Vanderbilt University; Estados UnidosFil: Matthews, Elisabeth C. Universidad de Ginebra; Suiza. Massachusetts Institute of Technology; Estados UnidosFil: Ziegler, Carl. University of Toronto; CanadáFil: Ricker, George. Massachusetts Institute of Technology; Estados UnidosFil: Vanderspek, Roland. Massachusetts Institute of Technology; Estados UnidosFil: Latham, David W. Harvard-Smithsonian Center for Astrophysics; Estados UnidosFil: Seager, S.. Massachusetts Institute of Technology; Estados UnidosFil: Winn, Joshua N.. University of Princeton; Estados UnidosFil: Jenkins, Jon M. NASA Ames Research Center; Estados UnidosFil: Acton, Jack S. University of Leicester; Reino UnidoFil: Addison, Brett C. University Of Southern Queensland; AustraliaFil: Diaz, Rodrigo Fernando. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Instituto de Ciencias FÃsicas. - Universidad Nacional de San MartÃn. Instituto de Ciencias FÃsicas; Argentin
TESS Asteroseismology of Mensae: Benchmark Ages for a G7 Dwarf and its M-dwarf Companion
Asteroseismology of bright stars has become increasingly important as a
method to determine fundamental properties (in particular ages) of stars. The
Kepler Space Telescope initiated a revolution by detecting oscillations in more
than 500 main-sequence and subgiant stars. However, most Kepler stars are
faint, and therefore have limited constraints from independent methods such as
long-baseline interferometry. Here, we present the discovery of solar-like
oscillations in Men A, a naked-eye (V=5.1) G7 dwarf in TESS's Southern
Continuous Viewing Zone. Using a combination of astrometry, spectroscopy, and
asteroseismology, we precisely characterize the solar analog alpha Men A (Teff
= 5569 +/- 62 K, R = 0.960 +/- 0.016 Rsun, M = 0.964 +/- 0.045 Msun). To
characterize the fully convective M dwarf companion, we derive empirical
relations to estimate mass, radius, and temperature given the absolute Gaia
magnitude and metallicity, yielding M = 0.169 +/- 0.006, R = 0.19 +/- 0.01 and
Teff = 3054 +/- 44 K. Our asteroseismic age of 6.2 +/- 1.4 (stat) +/- 0.6 (sys)
Gyr for the primary places Men B within a small population of M dwarfs
with precisely measured ages. We combined multiple ground-based spectroscopy
surveys to reveal an activity cycle of 13.1 +/- 1.1 years, a period similar to
that observed in the Sun. We used different gyrochronology models with the
asteroseismic age to estimate a rotation period of ~30 days for the primary.
Alpha Men A is now the closest (d=10pc) solar analog with a precise
asteroseismic age from space-based photometry, making it a prime target for
next-generation direct imaging missions searching for true Earth analogs.Comment: Accepted to The Astrophysical Journal; 15 pages, 10 figure
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