A Simple Analytical Model of Evaporation in the Presence of Roots

Root systems can influence the dynamics of evapotranspiration of water out of a porous medium. The coupling of evapotranspiration remains a key aspect affecting overall root behavior. Predicting the evapotranspiration curve in the presence of roots helps keep track of the amount of water that remains in the porous medium. Using a controlled visual set-up of a 2D model soil system consisting of monodisperse glass beads, we first perform experiments on actual roots grown in partially saturated systems under different relative humidity conditions. We record parameters such as the total mass loss in the medium and the resulting position of the receding fronts and use these experimental results to develop a simple analytical model that predicts the position of the evaporating front as a function of time as well as the total amount of water that is lost from the medium due to the combined effects of evaporation and transpiration. The model is based on fundamental principles of evaporation flux and includes empirical assumptions on the quantity of stoma in the leaves and the transition time between regime 1 and regime 2. The model also underscores the importance of a much prolonged root life as long as the root is exposed to a partially saturated zone composed of a mixture of air and water. Comparison between the model and experimental results shows good prediction of the position of the evaporating front as well as the total mass loss from evapotranspiration in the presence of real root systems. These results provide additional understanding of both complex evaporation phenomenon and its influence on root mechanisms.Comment: 10 pages, 6 figure

Spatially heterogeneous dynamics in a thermosensitive soft suspension before and after the glass transition

The microscopic dynamics and aging of a soft thermosensitive suspension was investigated by looking at the thermal fluctuations of tracers in the suspension. Below and above the glass transition, the dense microgel particles suspension was found to develop an heterogeneous dynamics, featured by a non Gaussian Probability Distribution Function (PDF) of the probes' displacements, with an exponential tail. We show that non Gaussian shapes are a characteristic of the ensemble-averaged PDF, while local PDF remain Gaussian. This shows that the scenario behind the non Gaussian van Hove functions is a spatially heterogeneous dynamics, characterized by a spatial distribution of locally homogeneous dynamical environments through the sample, on the considered time scales. We characterize these statistical distributions of dynamical environments, in the liquid, supercooled, and glass states, and show that it can explain the observed exponential tail of the van Hove functions observed in the concentrated states. The intensity of spatial heterogeneities was found to amplify with increasing volume fraction. In the aging regime, it tends to increase as the glass gets more arrested.Comment: 19 pages, 10 figures, Soft Matter accepte

Study of the Effects of the Enforcement of the Occupational Safety and Health Administration Standards on the Industrial Arts Program of Oklahoma Public Schools

The purpose of this study is to determine the effects of the adoption and enforcement of "The Occupational Safety and Health Act of 1970" on the Industrial Arts Program of Oklahoma Public Schools. At the present time, there is no occupational safety and health standards covering state agencies of Oklahoma. A questionnaire was developed to evaluate the present safety situation and conditions of the Industrial Arts School Shops. The primary question of the questionnaire covered the areas that would be effected by the enforcement of the Occupational Safety and Health Administration rules. Questionnaires were sent to 233 Oklahoma Public School Industrial Arts Teachers.Industrial Arts Educatio

Onset of efficacy and tolerability following the initiation dosing of long-acting paliperidone palmitate: post-hoc analyses of a randomized, double-blind clinical trial

<p>Abstract</p> <p>Background</p> <p>Paliperidone palmitate is a long-acting injectable atypical antipsychotic for the acute and maintenance treatment of adults with schizophrenia. The recommended initiation dosing regimen is 234 mg on Day 1 and 156 mg on Day 8 via intramuscular (deltoid) injection; followed by 39 to 234 mg once-monthly thereafter (deltoid or gluteal). These post-hoc analyses addressed two commonly encountered clinical issues regarding the initiation dosing: the time to onset of efficacy and the associated tolerability.</p> <p>Methods</p> <p>In a 13-week double-blind trial, 652 subjects with schizophrenia were randomized to paliperidone palmitate 39, 156, or 234 mg (corresponding to 25, 100, or 150 mg equivalents of paliperidone, respectively) or placebo (NCT#00590577). Subjects randomized to paliperidone palmitate received 234 mg on Day 1, followed by their randomized fixed dose on Day 8, and monthly thereafter, with no oral antipsychotic supplementation. The onset of efficacy was defined as the first timepoint where the paliperidone palmitate group showed significant improvement in the Positive and Negative Syndrome Scale (PANSS) score compared to placebo (Analysis of Covariance [ANCOVA] models and Last Observation Carried Forward [LOCF] methodology without adjusting for multiplicity) using data from the Days 4, 8, 22, and 36 assessments. Adverse event (AE) rates and relative risks (RR) with 95% confidence intervals (CI) versus placebo were determined.</p> <p>Results</p> <p>Paliperidone palmitate 234 mg on Day 1 was associated with greater improvement than placebo on Least Squares (LS) mean PANSS total score at Day 8 (p = 0.037). After the Day 8 injection of 156 mg, there was continued PANSS improvement at Day 22 (p ≤ 0.007 vs. placebo) and Day 36 (p < 0.001). Taken together with results in the 39 mg and 234 mg Day 8 arms, these findings suggest a trend towards a dose-dependent response. During Days 1 to 7, AEs reported in ≥2% of paliperidone palmitate subjects (234 mg) and a greater proportion of paliperidone palmitate than placebo subjects were: agitation (3.2% vs. 1.3%; RR 2.52 [95% CI 0.583, 10.904]), headache (4.0% vs. 3.8%; RR 1.06 [95% CI 0.433, 2.619]), and injection site pain (6.7% vs. 3.8%; RR 1.79 [95% CI 0.764, 4.208]). Days 8 to 36 AEs meeting the same criteria in the 156 mg Day 8 arm were: anxiety (3.1% vs. 2.5%; RR 1.24 [95% CI 0.340, 4.542]), psychotic disorder (2.5% vs. 1.3%; RR 1.99 [95% CI 0.369, 10.699]), dizziness (2.5% vs. 1.3%; RR 1.99 [95% CI 0.369, 10.699]), and injection site pain (2.5% vs. 1.3%; RR 1.99 [95% CI 0.369, 10.699]). Corresponding Days 8 to 36 AEs in the 39 mg Day 8 group were: agitation (4.5% vs. 4.4%; RR 1.03 [95% CI 0.371, 2.874]), anxiety (3.9% vs. 2.5%; RR 1.55 [95% CI 0.446, 5.381]), and psychotic disorder (2.6% vs. 1.3%; RR 2.07 [95% CI 0.384, 11.110]) while in the 234 mg Day 8 group it was anxiety (3.1% vs. 2.5%, RR 1.25 [95% CI 0.342, 4.570]).</p> <p>Conclusions</p> <p>Significantly greater symptom improvement was observed by Day 8 with paliperidone palmitate (234 mg on Day 1) compared to placebo; this effect was maintained after the 156 mg Day 8 injection, with a trend towards a dose-dependent response. No unexpected tolerability findings were noted in the first week or month after the initiation dosing.</p> <p>Trial registration</p> <p>ClinicalTrials.gov: <a href="http://www.clinicaltrials.gov/ct2/show/NCT#00590577">NCT#00590577</a></p

Characterizing the tropospheric ozone response to methane emission controls and the benefits to climate and air quality

Reducing methane (CH4) emissions is an attractive option for jointly addressing climate and ozone (O3) air quality goals. With multidecadal full-chemistry transient simulations in the MOZART-2 tropospheric chemistry model, we show that tropospheric O3 responds approximately linearly to changes in CH4 emissions over a range of anthropogenic emissions from 0–430 Tg CH4 a−1 (0.11–0.16 Tg tropospheric O3 or ∼11–15 ppt global mean surface O3 decrease per Tg a−1 CH4 reduced). We find that neither the air quality nor climate benefits depend strongly on the location of the CH4 emission reductions, implying that the lowest cost emission controls can be targeted. With a series of future (2005–2030) transient simulations, we demonstrate that cost-effective CH4 controls would offset the positive climate forcing from CH4 and O3 that would otherwise occur (from increases in NOx and CH4 emissions in the baseline scenario) and improve O3 air quality. We estimate that anthropogenic CH4 contributes 0.7 Wm−2 to climate forcing and ∼4 ppb to surface O3 in 2030 under the baseline scenario. Although the response of surface O3 to CH4 is relatively uniform spatially compared to that from other O3 precursors, it is strongest in regions where surface air mixes frequently with the free troposphere and where the local O3 formation regime is NOx-saturated. In the model, CH4 oxidation within the boundary layer (below ∼2.5 km) contributes more to surface O3 than CH4 oxidation in the free troposphere. In NOx-saturated regions, the surface O3 sensitivity to CH4 can be twice that of the global mean, with >70% of this sensitivity resulting from boundary layer oxidation of CH4. Accurately representing the NOx distribution is thus crucial for quantifying the O3 sensitivity to CH4

Accumulation of Individual Histone mRNAs during Embryogenesis of the Sea Urchin Strongylocentrotus purpuratus

We have determined that the stockpile of maternal histone mRNAs for both H2B and H3 in eggs of the sea urchin Strongylocentrotus purpuratus corresponds to 0.8–1 million molecules per egg. This value is a somewhat smaller quantity than had previously been estimated. On the other hand, the increase brought about by embryonic mRNA synthesis is 10- to 12-fold, rather than 4-fold. Further analysis of the time course of accumulation of these mRNAs suggests that histone gene expression in early development involves a complex interaction between activation of stockpiled maternal messengers, fluctuating rates of histone gene transcription, and alterations of histone mRNA stability. The maternal pool of H1 mRNA is considerably smaller (80,000 molecules). During cleavage, it partially catches up and peaks at about half the value for H2B and H3. We also examined previtellogenic oocytes for the presence of histone mRNAs by the same methods and were unable to detect any. Thus the stockpile of maternal histone mRNAs must accumulate after the previtellogenic stage of oogenesis

Results from the Intergovernmental Panel on Climatic Change Photochemical Model Intercomparison (PhotoComp)

Results from the Intergovernmental Panel on Climatic Change (IPCC) tropospheric photochemical model intercomparison (PhotoComp) are presented with a brief discussion of the factors that may contribute to differences in the modeled behaviors of HOx cycling and the accompanying O-3 tendencies. PhotoComp was a tightly controlled model experiment in which the IPCC 1994 assessment sought to determine the consistency among models that are used to predict changes in tropospheric ozone, an important greenhouse gas, Calculated tropospheric photodissociation rates displayed significant differences, with a root-mean-square (rms) error of the reported model results ranging from about +/-6-9% of the mean (for O-3 and NO2) to up to +/-15% (H2O2 and CH2O). Models using multistream methods in radiative transfer calculations showed distinctly higher rates for photodissociation of NO2 and CH2O compared to models using two-stream methods, and this difference accounted for up to one third of the rms error for these two rates, In general, some small but systematic differences between models were noted for the predicted chemical tendencies in cases that did not include reactions of nonmethane hydrocarbons (NMHC). These differences in modeled O-3 tendencies in some cases could be identified, for example, as being due to differences in photodissociation rates, but in others they could not and must be ascribed to unidentified errors. O-3 tendencies showed rms errors of about +/-10% in the moist, surface level cases with NOx concentrations equal to a few tens of parts per trillion by volume. Most of these model to model differences can be traced to differences in the destruction of O-3 due to reaction with HO2. Differences in HO2, in turn, are likely due to (1) inconsistent reaction rates used by the models for the conversion of HO2 to H2O2 and (2) differences in the model-calculated photolysis of H2O2 and CH2O. In the middle tropospheric ''polluted'' scenario with NOx concentrations larger than a few parts per billion by volume, O-3 tendencies showed rms errors of +/-10-30%. These model to model differences most likely stem from differences in the calculated rates of O-3 photolysis to O(D-1), which provides about 80% of the HOx source under these conditions. The introduction of hydrocarbons dramatically increased both the rate of NOx loss and its model to model differences, which, in turn, are reflected in an increased spread of predicted O-3. Including NMHC in the simulation approximately doubled the rms error for O-3 concentration