212 research outputs found
A history of Zonnebloem College, 1858-1870 : a study of church and society
Includes bibliographical references.The Kafir College was established as an Industrial Institution for the Instruction of the children of Native Chiefs and their Councillors at Bishop's Court, (1) the home of Bishop Gray in Claremont, in February, 1858. This experiment in education was the realization of the vision of two leading personalities of the time - Bishop Gray, the Metropolitan of the Anglican Church in South Africa (2) and Sir George Grey, Governor and High Commissioner of the Cape Colony. (3) The College was the combined venture of the Church and the British Government. They shared the financial responsibilities and when Zonnebloem, (4) a wine Term on the outskirts of Cape Town, was bought as a permanent site for the Institution in 1859, they both contributed towards the purchase price. Zonnebloem College came into being the following year when the students took up residence in their new quarters. The property, after first being transferred to Sir George Grey, was subsequently received back by Bishop Gray and it has been held in trust by the Lord Bishop of Cape Town ever since. The history of Zonnebloem can be divided into a number of distinct periods. While the College has functioned as an Educational Institution up to the present day, its purpose has changed at intervals over the years. It has altered direction and varied the scope of its work in order to meet the differing educational needs of the time. The student enrolment, too, has changed with time, for the College has of necessity been compelled to comply with the requirements of Government legislatio
Enabling learning through technology: Some institutional imperatives
This paper considers the importance of the institution as the dynamic interpretative element on which will depend the successful integration of the learning technology developed through our national initiatives into the academic curricula of Higher‐Education institutions. Based on our experience of working on teaching technology programmes, within the framework of national and institutional initiatives, it is evident that the establishment of an institutional strategy, and its implementation in a supporting university‐wide programme of staff development and training, together with strong commitment at the senior managerial level, are imperatives which determine the successful integration of learning technology within academic institutions
Journal of African Christian Biography: v. 2, no. 4
A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. The Martyrdom of Bernard Mizeki. 2. Bernard Mizeki. 3. Manche Masemola and Albert Luthuli: Iconic Figures of South African Christianity. 4. Manche Masemola. 5. Albert John Mvumbi Luthuli. 6. Multi-Talented Peacebuilder: Ambassador Dr. Bethuel A. Kiplagat. 7. Recent Print and Digital Resources Related to Christianity in Afric
Ntsikana : history and symbol studies in a process of religious change among Xhosa-speaking people
The figure of Ntsikana, both as a man of history and as an historical symbol, is the focus of this study. I argue that change may come about by giving new meanings to old forms and images or by taking the new forms and content and filling them with the old, and that these two sets continue to exist side by side for a long time. Cumpsty's "Model of Religious Change in Socio-Cultural Disturbance" is used to identify the dynamics in the process and to explore the nature of the dialectic between innovation and assimilation of the new on the one hand, and continuity with the old on the other. The Ntsikana tradition is followed ever a period of two hundred years and well illustrates the need to see religious change as part of an ongoing process within a particular social and historical context
Management of Insecticide-Resistant Soybean Aphids in the Upper Midwest of the United States
Since the first observation of soybean aphid, Aphis glycines Matsumura (Hemiptera: Aphididae), in North America in 2000, it has become the most economically damaging insect of soybean in the Upper Midwest of the United States. For the last 17 yr, soybean aphid management has relied almost entirely on the use of foliar-applied broad-spectrum insecticides. However, in 2015 in Minnesota, failures of foliar-applied pyrethroid insecticides were reported and pyrethroid resistance was confirmed with laboratory bioassays using lambda-cyhalothrin and bifenthrin. In 2016 and 2017, further reports of failures of pyrethroid insecticides and/or laboratory confirmation of resistance occurred in Iowa, North Dakota, South Dakota, and Manitoba. In response to the challenge posed by insecticide-resistant soybean aphids, we recommend several management strategies for minimizing further development of resistance and subsequent pest-induced crop losses: 1) scout and use the economic threshold to determine when to apply insecticides, 2) apply the insecticides properly, 3) assess efficacy 3–5 d after application, and 4) alternate to a different insecticide group if another application is required. In the long term, soybean aphid management must move beyond insecticide-based management to true integrated pest management by incorporating multiple tactics
What are the views of adults with an intellectual disability (AWID), carers and healthcare professionals on a community falls management programme for AWID: a qualitative interview study in the UK
Objectives The aim of this study was to refine a draft of the ACTiON FALLS LD programme based on the views of adults with an intellectual disability (AWID), carers and healthcare professionals (HCPs). Design, setting and participants The semistructured interview study included HCP as well as AWID and carers supporting AWID living in the community. Community settings included sheltered living, supported living, AWID living at home with family carers or independently. The interview study explored the first draft of the ACTiON FALLS LD programme as well as the wider falls management for AWID. Interviews with AWID were developed to include a range of approaches (eg, case studies, pictures) to support inclusive participation. Individual interviews were digitally recorded and transcribed. Researcher notes were used during interviews with AWID. All data were analysed using the principles of framework analysis. Results 14 HCP, 8 carers and 13 AWID took part in the interview process. Five key themes were identified: programme components, programme design, programme approach, who would use the programme and programme delivery. Conclusions The views of AWID, HCP and carers showed the need to consider the impact of risk perception, anxiety and fear of falling in the adaption of the ACTiON FALLS programme. The programme needs to be accessible and support the inclusion of AWID in managing falls and ultimately fulfil the requirement for a proactive and educational tool by all.</p
TMEM132: an ancient architecture of cohesin and immunoglobulin domains define a new family of neural adhesion molecules
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Common variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of Type II diabetes and multiple cancers. Evidence to date indicates that cancer risk may be mediated via genetic or epigenetic effects on HNF1B gene expression. We previously found single-nucleotide polymorphisms (SNPs) at the HNF1B locus to be associated with endometrial cancer, and now report extensive fine-mapping and in silico and laboratory analyses of this locus. Analysis of 1184 genotyped and imputed SNPs in 6608 Caucasian cases and 37 925 controls, and 895 Asian cases and 1968 controls, revealed the best signal of association for SNP rs11263763 (P = 8.4 × 10(-14), odds ratio = 0.86, 95% confidence interval = 0.82-0.89), located within HNF1B intron 1. Haplotype analysis and conditional analyses provide no evidence of further independent endometrial cancer risk variants at this locus. SNP rs11263763 genotype was associated with HNF1B mRNA expression but not with HNF1B methylation in endometrial tumor samples from The Cancer Genome Atlas. Genetic analyses prioritized rs11263763 and four other SNPs in high-to-moderate linkage disequilibrium as the most likely causal SNPs. Three of these SNPs map to the extended HNF1B promoter based on chromatin marks extending from the minimal promoter region. Reporter assays demonstrated that this extended region reduces activity in combination with the minimal HNF1B promoter, and that the minor alleles of rs11263763 or rs8064454 are associated with decreased HNF1B promoter activity. Our findings provide evidence for a single signal associated with endometrial cancer risk at the HNF1B locus, and that risk is likely mediated via altered HNF1B gene expression
- …