126 research outputs found
A global evaluation of streamflow drought characteristics
How drought is characterised depends on the purpose and region of the study and the available data. In case of regional applications or global comparison a standardisation of the methodology to characterise drought is preferable. In this study the threshold level method in combination with three common pooling procedures is applied to daily streamflow series from a wide range of hydrological regimes. Drought deficit characteristics, such as drought duration and deficit volume, are derived, and the methods are evaluated for their applicability for regional studies. Three different pooling procedures are evaluated: the moving-average procedure (MA-procedure), the inter-event time method (IT-method), and the sequent peak algorithm (SPA). The MA-procedure proved to be a flexible approach for the different series, and its parameter, the averaging interval, can easily be optimised for each stream. However, it modifies the discharge series and might introduce dependency between drought events. For the IT-method it is more difficult to find an optimal value for its parameter, the length of the excess period, in particular for flashy streams. The SPA can only be recommended as pooling procedure for the selection of annual maximum series of deficit characteristics and for very low threshold levels to ensure that events occurring shortly after major events are recognized. Furthermore, a frequency analysis of deficit volume and duration is conducted based on partial duration series of drought events. According to extreme value theory, excesses over a certain limit are Generalized Pareto (GP) distributed. It was found that this model indeed performed better than or equally to other distribution models. In general, the GP-model could be used for streams of all regime types. However, for intermittent streams, zero-flow periods should be treated as censored data. For catchments with frost during the winter season, summer and winter droughts have to be analysed separately
Intermittent mild negative pressure applied to the lower limb in patients with spinal cord injury and chronic lower limb ulcers: a crossover pilot study
Study design
Randomized, assessor-blinded crossover pilot study.
Objectives
To explore the use of an intermittent negative pressure (INP) device for home use in addition to standard wound care (SWC) for patients with spinal cord injury (SCI) and chronic leg and foot ulcers before conducting a superiority trial.
Setting
Patient homes and outpatient clinic.
Methods
A 16-week crossover trial on 9 SCI patients (median age: 57 years, interquartile range [IQR] 52â66), with leg ulcers for 52 of weeks (IQR: 12â82) duration. At baseline, patients were allocated to treatment with INPâ+âSWC or SWC alone. After 8 weeks, the ulcers were evaluated. To assess protocol adherence, the patients were then crossed over to the other group and were evaluated again after another 8 weeks. Lower limb INP treatment consisted of an airtight pressure chamber connected to an INP generator (alternating 10âs â40mmHg/7âs atmospheric pressure) used 2âh/day at home. Ulcer healing was assessed using a photographic wound assessment tool (PWAT) and by measuring changes in wound surface area (WSA).
Results
Seven of nine recruited patients adhered to a median of 90% (IQR: 80â96) of the prescribed 8-week INP-protocol, and completed the study without side effects. PWAT improvement was observed in 4/4 patients for INPâ+âSWC vs. 2/5 patients for SWC alone (Pâ=â0.13). WSA improved in 3/4 patients allocated to INPâ+âSWC vs. 3/5 patients in SWC alone (Pâ=â0.72).
Conclusions
INP can be used as a home-based treatment for patients with SCI, and its efficacy should be tested in an adequately sized, preferably multicenter randomized trial.mÄsjekke
Fluctuation in Shear Rate, with Unaltered Mean Shear Rate, Improves Brachial Artery Flow-Mediated Dilation in Healthy, Young Men.
AIM: Increase in mean shear stress represents an important and potent hemodynamic stimulus to improve conduit artery endothelial function in humans. No previous study has examined whether fluctuations in shear rate patterns, without altering mean shear stress, impacts conduit artery endothelial function. This study examined the hypothesis that 30-minutes exposure to fluctuations in shear rate patterns, in the presence of unaltered mean shear rate, improves brachial artery flow-mediated dilation. METHODS: Fifteen healthy males (27.3±5.0 years) completed the study. Bilateral brachial artery flow-mediated dilation was assessed before and after unilateral exposure to 30-minutes of intermittent negative pressure (10seconds -40mmHg, 7seconds 0mmHg) to induce fluctuation in shear rate, whilst the contra-lateral arm was exposed to a resting period. RESULTS: Negative pressure significantly increased shear rate, followed by a decrease in shear rate upon pressure release (both P<0.001). Across the 30-minute intervention, mean shear rate was not different compared to baseline (P=0.458). A linear mixed model revealed a significant effect of time was observed for flow-mediated dilation (P=0.029), with exploratory post-hoc analysis showing an increase in the intervention arm (âFMD +2.0%, P=0.008), but not in the contra-lateral control arm (âFMD +0.5%, P=0.664). However, there was no effect for arm (P=0.619) or interaction effect (P=0.096). CONCLUSION: In conclusion, we found that fluctuations in shear patterns, with unaltered mean shear, improves brachial artery flow-mediated dilation. These novel data suggest that fluctuations in shear pattern, even in the absence of altered mean shear, represents a stimulus to acute change in endothelial function in healthy individuals
A comparison of bioclimatic conditions on Franz Josef Land (the Arctic) between the turn of the nineteenth to twentieth century and present day
The paper presents the variability of meteorological conditions: air temperature, wind speed and relative air humidity; and biometeorological indices: wind chill temperature, predicted clothing insulation and accepted level of physical activity on
Franz Josef Land (in Teplitz Bay and Calm Bay) in the years 1899â1931. It employs meteorological measurements taken during four scientific expeditions to the study area. The analysis mainly covered the period OctoberâApril, for which the most complete data set is available. For that period of the year, which includes the part of the year with the Franz Josef Landâs coldest air temperatures, the range and nature of changes in meteorological and biometeorological conditions between historical periods and the modern period (1981â2010) were studied. The data analysis revealed that during the three oldest expeditions (which took place in the years 1899â1914), the biometeorological conditions in the study area were more harsh to humans than in the modern period (1981â2010) or similarly harsh. In contrast, during the 1930/1931 expedition, which represents the Early Twentieth CenturyWarming (ETCW), conditions were clearly more favourable (including predicted clothing insulation being 0.3 clo lower and 4.0 °C higher wind chill temperature than conditions observed nowadays)
Air temperature variations and gradients along the coast and fjords of western Spitsbergen
Daily temperature measurements from six meteorological stations along the coast and fjords of western Spitsbergen have been digitized and quality controlled in a Norwegian, Russian and Polish collaboration. Complete daily data series have been reconstructed back to 1948 for all of the stations. One of the stationâs monthly temperature series has previously been extended back to 1898 and is included in this study. The long-term series show large temperature variability on western Spitsbergen with colder periods in the 1910s and 1960s and warmer periods in the 1930s, 1950s and in the 21st century. The most recent years are the warmest ones in the instrumental records. There is a
positive and statistically significant trend in the annual times series for all of the stations; however, the strongest warming is seen in winter and spring. For the period 1979-2015, the linear trends range from 1.0 to 1.38°C/decade for the annual series and from 2.0 to 2.38°C/decade in winter. Threshold statistics demonstrate a decrease in the number of cold days per year and an increase in the number of warm days. A decreasing inter-annual variability is observed. In winter, spring and autumn, the stations in the northernmost areas of west Spitsbergen and in the innermost parts of Isfjorden are the coldest ones. In summer, however, the southernmost station is the coldest one
Light in the Polar Night
How much light isa vailable for biological processes during Polar Night? This question appears simple enough. But the reality is that conventional light sen- sors for measuring visible light (~350 to ~700 nm) have not been sensitive enough to answer it. Beyond this technical challenge, âlightâ is a general term that must be qualified in terms of âlight climateâ before it has meaning for biological systems. In this chapter, we provide an answer to the question posed above and explore aspects of light climate during Polar Night with relevance to biology, specifically, how Polar Night is defined by solar elevation, atmospheric light in Polar Night and its propaga- tion underwater, bioluminescence in Polar Night and the concept of Polar Night as a deep-sea analogue, light pollution, and future perspectives. This chapter focuses on the quantity and quality of light present during Polar Night, while subsequent chapters in this volume focus on specific biological effects of this light for algae (Chap. âMarine Micro- and Macroalgae in the Polar Nightâ), zooplankton (Chaps.âZooplankton in the Polar Nightâ and âBiological Clocks and Rhythms in Polar Organismsâ), and fish (Chap. âFish Ecology in the Polar Nightâ)
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