42 research outputs found
The effects of macroeconomics determinants towards the performance of property stock market in Malaysia / Muhammad Nur Hijazi Jasmon
The aim of this paper is to examine the effects of macroeconomic determinants towards
the property stock market performance in Malaysia. The property stock market performance of
Malaysia was chosen as the dependent variable in this study. There are five independent
variables to be use in the study which are Growth Rate of Gross Domestic Product (GDP),
Inflation Rate, Exchange Rate, Money Supply (M2) and Industry Production Output Growth
Rate.
The data were gathered from annual data year 1985 to 2013. The data was gathered from
DataStream and World Data Bank. A multiple linear regression is used in this study. In addition,
the econometric tests are employed to observe the relationship of the economic variables to the
performance of property stock market in Malaysia. The interactive package E-View is used in
order to run the test and analysis on the data collected. Thus, trough the data testing, it is going to
show how the variable are related each other.
It is expected that the most of the data findings on the variable are going to be significant.
This is based on previous study made by many researchers that found the finding are
significantly related between dependent and independent variables. As tested by(Thim et al,
2012), (Liow et al, 2006), (Liow, Ibrahim, & Huang, 2014), (Ong, 2013), (West, 2006a), and
(Duca, 2007
PILGRIM PRAYER LAW BASED ON THE PERSPECTIVE OF MUHAMMADIYAH LEADERS IN ENREKANG REGENCY, SOUTH SULAWESI
Research on Pilgrim Prayer Law Based on the Perspective of Muhammadiyah Leaders in Enrekang Regency, South Sulawesi is Qualitative. As stated in the formulation of the problem, in addition to researching the Pilgrim Prayer Law Based on the Perspective of the Muhammadiyah Leadership in Enrekang Regency, the researcher also examined the Pilgrim Prayer Law Based on the Perspective of the Imams of the four schools, namely the Hanafi School, the Maliki School, the Shafi'i School and the Hanbali School . This study aims to find out the extent of the perspectives of the Muhammadiyah Leadership and the Imam of the Four Schools on the law of pilgrim prayer. This is in order to increase understanding, both among intellectuals and among the layman. The results of this study show that the scholars of the four schools have different opinions about the law of prayer of pilgrims. Imam Abu Hanifah An- Nu'man bin Tsabit stated that the pilgrim's prayer was the sunnah of mu'akkadah. Imam Malik bin Anas stated that the law of pilgrim prayer is the sunnah of mu'akkadah. Imam Muhammad ibn Idris As-Shafi'i stated that the pilgrim's prayer was fardhu kifayah. Imam Ahmad ibn Hanbal stated that the law of pilgrim prayer is mandatory. As for the perspective of the Muhammadiyah Regional Leader (PDM), Enrekang Regency stated that the pilgrim's prayer is fardhu kifayah. This opinion is in harmony with the opinion of Imam Shafi'i and is also in harmony with the tarjih of muhammadiyah.--Penelitian tentang Hukum Shalat Jamaah Berdasarkan Perspektif Pimpinan Muhammadiyah di Kabupaten Enrekang Sulawesi Selatan bersifat Kualitatif. Sebagaimana yang tertera pada rumusan masalah, selain meneliti tentang Hukum Shalat Jamaah Berdasarkan Perspektif Pimpinan Muhammadiyah di Kabupaten Enrekang, peneliti juga meneliti Hukum Shalat Jamaah Berdasarkan Perspektif imam empat mazhab, yaitu Mazhab Hanafi, Mazhab Maliki, Mazhab Syafi’i dan Mazhab Hanbali. Penelitian ini bertujuan untuk mengetahui sejauh mana perspektif Pimpinan Muhammadiyah dan Imam Empat Mazhab tentang hukum shalat jamaah ini. Hal ini agar dapat menambah pemahaman, baik itu di kalangan intelektual maupun di kalangan awam. Hasil dari penelitian ini menunjukkan bahwa ulama empat mazhab berbeda pendapat tentang hukum shalat jamaah ini. Imam Abu Hanifah An- Nu’man bin Tsabit menyatakan bahwa shalat jamaah hukumnya adalah sunnah mu’akkadah. Imam Malik bin Anas menyatakan bahwa hukum shalat jamaah adalah sunnah mu’akkadah. Imam Muhammad bin Idris As-Syafi’i menyatakan bahwa shalat jamaah hukumnya adalah fardhu kifayah. Imam Ahmad bin Hanbal menyatakan bahwa hukum shalat jamaah adalah wajib. Adapun mengenai perspektif Pimpinan Daerah Muhammadiyah (PDM) Kab. Enrekang menyatakan bahwa shalat jamaah hukumnya adalah fardhu kifayah. Pendapat ini selaras dengan pendapat Imam Syafi’i dan juga selaras dengan tarjih muhammadiyah
The impact of cultural healthcare practices on Children’s health in the United Arab Emirates: a qualitative study of traditional remedies and implications
AimThis qualitative study investigates the impact of cultural practices on children’s health in the United Arab Emirates (UAE) by examining the use of traditional remedies and home treatments by mothers.MethodsTwenty-five participants, all mothers who had employed traditional treatments or home remedies for their children during periods of illness, were included in the study. The participants represented a diverse range of educational backgrounds, from school diploma holders to university degree graduates, with ages spanning from 20 to 50 years. Hailing from different Arabic countries and cultural subgroups, the majority of participating mothers were from the UAE.ResultsThrough in-depth interviews, three major themes emerged from the participants’ experiences. Firstly, a strong connection between culture, religion, and healthcare practices was evident. Many mothers opted for cultural remedies as their first line of defense against illnesses due to the practices’ strong foundations in their cultural heritage. Herbal remedies, Quranic healing, and other traditional methods were perceived to be both effective and spiritually comforting, reinforcing participants’ sense of cultural identity. Secondly, participants highlighted unintended consequences of relying solely on traditional treatments. Some instances were reported where the use of ineffective remedies resulted in delays in seeking appropriate medical care for their children, potentially compromising their health. Additionally, certain misconceptions regarding the safety and efficacy of traditional remedies were identified, emphasizing the need for evidence-based healthcare education.ConclusionThis qualitative study sheds light on the intricate interplay between culture, traditional remedies, and children’s health in the UAE. The incorporation of diverse participants from various Arabic countries and cultural subgroups enriches the study’s applicability to broader Arabic cultures. By recognizing the significance of cultural healthcare practices and striking a balance with evidence-based care, healthcare providers can create a more inclusive and effective healthcare environment for children in the UAE. Future research should explore diverse samples and develop targeted interventions to further advance cultural awareness and understanding in healthcare practices
Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity
The recent COVID-19 pandemic shows the critical need for novel broad spectrum antiviral agents. Scorpion venoms are known to contain highly bioactive peptides, several of which have demonstrated strong antiviral activity against a range of viruses. We have generated the first annotated reference transcriptome for the Androctonus amoreuxi venom gland and used high performance liquid chromatography, transcriptome mining, circular dichroism and mass spectrometric analysis to purify and characterize twelve previously undescribed venom peptides. Selected peptides were tested for binding to the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein and inhibition of the spike RBD – human angiotensin-converting enzyme 2 (hACE2) interaction using surface plasmon resonance-based assays. Seven peptides showed dose-dependent inhibitory effects, albeit with IC50 in the high micromolar range (117–1202 µM). The most active peptide was synthesized using solid phase peptide synthesis and tested for its antiviral activity against SARS-CoV-2 (Lineage B.1.1.7). On exposure to the synthetic peptide of a human lung cell line infected with replication-competent SARS-CoV-2, we observed an IC50 of 200 nM, which was nearly 600-fold lower than that observed in the RBD – hACE2 binding inhibition assay. Our results show that scorpion venom peptides can inhibit the SARS-CoV-2 replication although unlikely through inhibition of spike RBD – hACE2 interaction as the primary mode of action. Scorpion venom peptides represent excellent scaffolds for design of novel anti-SARS-CoV-2 constrained peptides. Future studies should fully explore their antiviral mode of action as well as the structural dynamics of inhibition of target virus-host interactions
Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey
Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised