On the design and simulation of an airlift loop bioreactor with microbubble generation by fluidic oscillation

Microbubble generation by a novel fluidic oscillator driven approach is analyzed, with a view to identifying the key design elements and their differences from standard approaches to airlift loop bioreactor design. The microbubble generation mechanism has been shown to achieve high mass transfer rates by the decrease of the bubble diameter, by hydrodynamic stabilization that avoids coalescence increasing the bubble diameter, and by longer residence times offsetting slower convection. The fluidic oscillator approach also decreases the friction losses in pipe networks and in nozzles/diffusers due to boundary layer disruption, so there is actually an energetic consumption savings in using this approach over steady flow. These dual advantages make the microbubble generation approach a promising component of a novel airlift loop bioreactor whose design is presented here. The equipment, control system for flow and temperature, and the optimization of the nozzle bank for the gas distribution system are presented. (C) 2009 The Institution of Chemical Engineers. Published by Elsevier B.V All rights reserved

Characterisation of an analogue liquid for hydrodynamic studies of gas-ionic liquid flows

Ionic liquids are liquid salts at low temperatures (normally less than 100°C). They are powerful solvents with very low vapour pressure. They have great potentials in many applications such as gas absorption and chemical synthesis. However, they are expensive. This limits extensive studies towards establishing phenomenological models. To address this limitation, an analogue liquid, with properties similar to an ionic liquid, has been identified which on the grounds of cost and safety appears to be suitable. In this paper, the hydrodynamic behaviour of an ionic liquid in a bubble column is compared with those of water and other liquids with similar physical properties. Average gas holdup, bubble coalescence, bubble size and specific interfacial area with different liquids are examined. Gas hold-up was determined by monitoring the change of conductivity between two flush mounted rings. The differences in bubble size and coalescence are revealed by analysing the stills taken from a high speed video camera. The dominant flow pattern in a small diameter column with ionic liquids or other fluids having similar viscosity is slug flow. The small bubbles in the liquid slugs make a smaller contribution to the specific interfacial area than Taylor bubbles. It is observed that Taylor bubbles can coalesce. The hydrodynamics of an ionic liquid in a bubble column can be estimated from that of a fluid with similar physical properties

Cellulosic-crystals as a fumed-silica substitute in vacuum insulated panel technology used in building construction and retrofit applications

This article investigates impact of substituting fumed silica with a cellulosic-crystal innovation in a commercial Vacuum Insulated Panel (VIP) core. High building performance demands have attracted VIP technology investment to increase production capacity and reduce cost. In building retrofit VIPs resolve practical problems on space saving that conventional insulations are unsuitable for. Three challenges exists in fumed silica: cost, low sustainability properties, and manufacture technical maturity. Cellulosic nano-crystal (CNC) technology is in its infancy and was identified as a possible alternative due to a similar physical nano-structure, and biodegradability. The study aim was to determine a performance starting point and establish how this compares with the current benchmarks. Laboratory cellulosic-crystal samples were produced and supplied for incorporation into commercial VIP manufacture. A selection of cellulosic-panels with core densities ranging 127–170 kg/m3 were produced. Thermal conductivities were tested at a pressure of 1 Pa (0.01 mBar), with the results compared against a selection of fumed silica-VIPs with core densities ranging 144–180 kg/m3. Conductivity tests were then done on a cellulosic-VIP with 140 kg/m3 density, under variable pressures ranging 1–100,000 Pa (0.01–1000 mBar). This investigated panel lifespan performance, with comparisons made to a fumed silica-VIP of similar core density. Manufactured cellulosic-samples were found unsuitable as a commercial substitute, with performance below current standards. Areas for cellulosic nano-material technology development were identified that show large scope for improvement. Pursuit could create a new generation of insulation materials that resolve problems associated with current commercial versions. This is most applicable in building retrofit where large ranges of domestic and commercial cases are marginalised from their construction markets due to impracticalities and high upgrade costs. This being a problem in multiple economies globally

Interfacial dynamics driven by Marangoni stresses on a slowly moving liquid film.

Differential surface tension is a common phenomenon in many chemical and biomedical processes. Localised surface tension gradients due to differential surface loading in thin films give rise to a moving shock front in the direction of higher surface tension. Existence of a background flow enhances the shock wave giving rise to wave breaking and wave separation mechanisms. The effect of a background flow field on Marangoni stress induced shock fronts were investigated in this thesis. Furthermore, a numerical procedure to find approximate solutions to the fully nonlinear flow problem that arises due to Marangoni spreading is proposed. A set of surface evolution equations that incorporates the effects of the background flow field is studied in two major respects: (i) breaking the horizontal symmetry and (ii) nonlinear accretion leading to shock front breaking or separation. The evolution of the surface is evaluated by numerical simulations for a wide range of parameter values. The investigation showed that there are two breaking mechanisms switched by the value of Peclet number. Furthermore it showed that the life time of the shock front is determined by the volumetric flow rate of the film. It is shown here that a weak Marangoni force generates a pure capillary gravity wave that propagates faster than the surfactant front. It is customary to use the lubrication approximations to simplify thin film problems. As a result, the inertial terms in flow equations and nonlinear terms in surface stress balances become excluded. To analyse the fully nonlinear flow, a finite element (FEM) analysis is proposed. The simulations shows that the lubrication theory holds globally in predicting the spreading rates but fails to do so locally until a quasi-steady state is reached. The FEM model shows the formation of two counter-rotating vortices at the beginning which diminish as time evolves. The FEM results are compared with the lubrication theory simulations. FEM model shows rapid film thinning forming extremely thin films within a short period of time. Though detailed transport mechanisms differ, both methods are in close agreement in predicting the spreading rates

Social skills disparities in the transition from pediatric to adult care among children with special health care needs

As increasing numbers of Children with Special Health Care Needs (CSHCN) reach adulthood, the need for support and preparation for the eventual transition process to adult care have been widely recognized. For children with lifelong chronic medical conditions, mastery of self-care skills is a vital component of the transition process. It is important to assess skills related to healthcare transition in order to determine appropriate supports and interventions. Transition Readiness Assessment Questionnaire (TRAQ) is an accepted and validated tool that measures readiness to transition for CSHCN. The aim of this study was to analyze TRAQ data in order to identify whether social skills disparities exist in the transition from pediatric to adult care among CSHCN. This was a quantitative study using secondary data analysis of TRAQ obtained from California Children's Services (CCS) in Kern County, California. Social skills disparities among Spanish and English speaking CCS adolescents, both male and female, between the ages of 14 and 21 were analyzed using descriptive statistics. In addition, Spanish and English speaking parents/caregivers who participated in TRAQ were also analyzed. Of 202 total TRAQ records, 138 were completed by CCS youths and 64 were by parents/caregivers. The findings did, in fact, show that social skills disparities exist in the transition process to adult care among CCS CSHCN as well as parents/caregivers. There were significant age, gender, and language differences in Social Skills Abilities (SSA) scores among CCS adolescents. Parents/caregivers also showed disparities in SSA scores based on language. In order to address social skills disparities among CCS youths and parents/caregivers, recommendations were provided for ongoing social skills development through role-playing, real life training, mentoring, and parent-child grouping

Optimised mode selection in electromagnetic sensors for real time, continuous and in-situ monitoring of water cut in multi-phase flow systems

Measurements of the composition of multiphase flows, especially water-cut in oil-water flow, is a frequently encountered problem in the petroleum industry. New techniques that can offer improvements towards that are continuously sought and the use of microwave sensors is considered very promising. The current paper reports on the performance of a microwave cylindrical resonator, integrated into a multiphase flow experimental facility, used to determine water-cut in an upward flowing oil-water mixture. The performance and suitability of two microwave resonant modes (TM010 and TM110) was studied. The TM110 mode was found to be less dependent on the spatial phase distribution of the oil-water flowing mixture and provided more consistent results across a broader flow regime. The relative errors between the predicted and actual water-cut were from −6.53% to 9.16% and relative errors of 78% of the total data points were inside −5% to 5%. The results suggest that appropriate sensor design and careful selection of the operating frequency/resonant pattern can offer a powerful technique for real time, on-line and non-destructive determination of water-cut in multiphase flow systems

Gas rising through a large diameter column of very viscous liquid: Flow patterns and their dynamic characteristics

Gas-liquid flows are affected strongly by both the liquid and gas properties and the pipe diameter, which control features and the stability of flow patterns and their transitions. For this reason, empirical models describing the flow dynamics can be applied only to limited range of conditions. Experiments were carried out to study the behaviour of air passing through silicone oil (360 Pa.s) in 240 mm diameter bubble column using Electrical Capacitance Tomography and pressure transducers mounted on the wall. These experiments are aimed at reproducing expected conditions for flows including (but not limited to) crude oils, bitumen, and magmatic flows in volcanic conduits. The paper presents observation and quantification of the flow patterns present. It particularly provides the characteristics of gas-liquid slug flows such as: void fraction; Taylor bubble velocity; frequency of periodic structures; lengths of liquid slugs and Taylor bubbles. An additional flow pattern, churn flow, has been identified. The transition between slug and churn has been quantified and the mechanism causing it are elucidated with the assistance of a model for the draining of the liquid film surrounding the Taylor bubble once this has burst through the top surface of the aerated column of gas-liquid mixture. It is noted that the transition from slug to churn is gradual

Numerical studies of shear-thinning droplet formation in a microfluidic T-junction using two-phase level-set method

A conservative level-set method (LSM) embedded in a computational fluid dynamics (CFD) simulation provides a useful approach for the studying the physics and underlying mechanism in two-phase flow. Detailed two-dimensional (2D) computational microfluidics flow simulations have been carried out to examine systematically the influence of different controlling parameters such as flow rates, viscosities, surface wettability, and interfacial tensions between two immiscible fluids on the non-Newtonian shear-thinning microdroplets generation process. For the two-phase flow system that neglects the Marangoni effect, the breakup process of shear-thinning microdroplets in cross-flowing immiscible liquids in a microfluidic device with a T-shaped geometry was predicted. Data for the rheological and physical properties of fluids obeying Carreau-Yasuda stress model were empirically obtained to support the computational work. The simulation results show that the relevant control parameters mentioned above have a strong impact on the size of shear-thinning droplets generated. Present computational studies on the role and relative importance of controlling parameters can be established as a conceptual framework of the non-Newtonian droplet generation process and relevant phenomena for future studies

Fluid structure behaviour in gas-oil two-phase flow in a moderately large diameter vertical pipe

Intermittent flows in vertical pipes occur in many industrial settings including power generation and downstream oil-and gas production. This type of flows include cap bubble, slug and churn flow regimes. These regimes are of interest as downstream processes and control may heavily depend on the intermittency of the inflow. There are a number of correlations that predicts the features in such flows in vertical pipes. Most of the correlations were developed for air and water fluid pair for slug flow regime in vertical pipes with 25 to 50 mm inner diameter. In this paper, an attempt has been made to assess the suitability of several of these correlations specific to slug flow regime for a fluid pair that is different to air-water system. In this work, air-silicone oil flow development was experimentally investigated in a vertical pipe with an inner diameter of 68mm. A Wire Mesh Sensor (WMS) and an Electrical Capacitance Tomography (ECT) sensor were installed in series at four locations (15D, 30D, 45D and 65D) downstream of the mixing section. The flow was visually observed using a high speed camera. The void fraction time series obtained from the WMS and the ECT were used to establish the flow characteristics such as slug length, slug frequency, void fraction in liquid slugs and Taylor bubble velocity. A comparison showed that the void fraction measurements using ECT and WMS are in good agreement. Axial measurements shows that the flow development beyond 45D is minimal. Change in physical properties of the liquid phase is responsible for the deviation associated with the existing slug flow models, particularly those developed to predict the gas holdup in liquid slugs