26 research outputs found

    Entrenamiento por Competencias de ComputaciĂłn de Alto Rendimiento para Ecosistemas de ComputaciĂłn Avanzada

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    peer reviewedHigh-Performance Computing (HPC) is one of the pillars of developing modern science and disruptive technologies, uniting computer architectures and parallel programming into multidisciplinary interactions to face domain-specific problems. That is why different areas of knowledge require their future professionals (scientists or not) to acquire skills in using HPC. The Super Computing and Distributed Systems Camping School, SC-Camp, is a non-profit activity that proposes a series of courses about HPC with an important focus on practical sessions (more than half of the time) addressed to undergraduate and graduate students who could benefit from HPC by demand. It is an itinerant school, bringing the HPC knowledge to a different place every year, focusing on diversity, sustainability, and humanity.La computaciĂłn de alto rendimiento (HPC) es uno de los pilares del desarrollo de la ciencia moderna y las tecnologĂ­as disruptivas, uniendo arquitecturas informĂĄticas y programaciĂłn paralela en interacciones multidisciplinarias para enfrentar problemas especĂ­ficos de dominio. Es por ello que distintas ĂĄreas del conocimiento exigen a sus futuros profesionales (cientĂ­ficos o no) adquirir habilidades en el uso de HPC. El Camping Escuela de Super ComputaciĂłn y Sistemas Distribuidos, SC-Camp, es una actividad sinĂĄnimo de lucro que propone una serie de cursos sobre HPC con un importante foco en sesiones prĂĄcticas (mĂĄs de la mitad del tiempo) dirigidas a estudiantes de grado y posgrado que podrĂ­an beneficiarse de HPC segĂșn la demanda. Es una escuela itinerante, quelleva el conocimiento de HPC a un lugar diferente cada año, con un enfoque importante en la diversidad, la sostenibilidad y la humanidad

    InvestigaciĂłn en MatemĂĄticas, EconomĂ­a, Ciencias Sociales y AgronomĂ­a

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    Cada trabajo del libro incluye conclusiones para los interesados en las temĂĄticas aludidas y en ellos nos enteramos de aspectos como los siguientes: - El mayor incremento del precio de los insumos como el maĂ­z, sorgo y en menor medida desperdicio de pan, en relaciĂłn con el menor crecimiento del precio del ganado en pie, darĂĄ como consecuencia un desabasto de carne bovina. - El agua es un recurso primordial en las zonas ĂĄridas y semiĂĄridas de MĂ©xico, en tanto que su aporte limita la producciĂłn de la agricultura. En este estudio se observĂł que el precio real del agua es muy bajo en relaciĂłn a otras zonas agrĂ­colas del mundo. - Hoy en dĂ­a en el paĂ­s se consumen alrededor de 718 mil barriles diarios de gasolinas, un aproximado de 113.7 millones de litros, una cantidad tan grande que nuestro paĂ­s se ve en la necesidad de importar cerca del 39 % de las gasolinas que consumimos. - Los jaliscienses radicados en Estados Unidos tienen una mayor capacidad de financiamiento del bienestar en la entidad, que el propio gobierno de ese estado. - MĂ©xico continuarĂĄ basando sus finanzas pĂșblicas y su polĂ­tica de desarrollo econĂłmico en la extracciĂłn de combustibles fĂłsiles (petrĂłleo). Este modelo acelerarĂĄ el deterioro y agotamiento de los recursos naturales. -La importancia de la agricultura orgĂĄnica radica en que retoma los tres ĂĄmbitos de la sustentabilidad; el ĂĄmbito ambiental, el econĂłmico y el social. - Es fundamental motivar la organizaciĂłn de los productores de haba para que ellos puedan captar una mayor proporciĂłn de los altos mĂĄrgenes de precios que los consumidores estĂĄn dispuestos a pagar. - Las condiciones del clima afectan a la producciĂłn agraria. Debido al fenĂłmeno de cambio climĂĄtico, es necesario contar con herramientas informĂĄticas que proporcionen informaciĂłn climatolĂłgica para poder tomar medidas preventivas a favor de una mayor cantidad y calidad de producciĂłn. La herramienta de software permite la consulta del clima por localidades evitando la necesidad de contar con una estaciĂłn meteorolĂłgica

    Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

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    BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    ETUDE DE TRANSFERT HAUT DEBIT SUR DES GRILLES DE CALCUL

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    This thesis paper proposes a realistic performance evaluation technique for broadband data transfer during the execution of Grid Computing applications.The work consisted in analysing the different possibilities of implementing the deterministic model in order to obtain a correct description of the process of parallel and massive data transfer. As a result :- The model is easy to implement in performance evaluation techniques and tools.- The performance evaluation techniques and derived tools should be operated in real life and provide real-time information.This paper also proposes a model to predict the transfer of massive parallel data between nodes during the execution of applications running on grid computing platforms.This work has identified the main characteristics that affect communication performance during massive parallel data transfer. These characteristics are related to parameters that describe the interactions between the application and the infrastructure resources, in terms of capacity, availability and utilisation.Ce document de thĂšse propose une technique rĂ©aliste d'Ă©valuation des performances pour le transfert de donnĂ©es Ă  large bande pendant l'exĂ©cution d'applications de Grid Computing.Le travail a consistĂ© Ă  analyser les diffĂ©rentes possibilitĂ©s de mise en Ɠuvre du modĂšle dĂ©terministe afin d'obtenir une description correcte du processus de transfert de donnĂ©es parallĂšles et massives. En consĂ©quence :- Le modĂšle est facile Ă  mettre en Ɠuvre dans les techniques et les outils d'Ă©valuation de la performance.- Les techniques d'Ă©valuation des performances et les outils dĂ©rivĂ©s devraient ĂȘtre exploitĂ©s en situation rĂ©elle et fournir des informations en temps rĂ©el.Ce document propose aussi un modĂšle pour prĂ©dire le transfert de donnĂ©es parallĂšles et massives entre les nƓuds pendant l'exĂ©cution des applications qui tournent sur des plates-formes de calcul en grille.Ce travail a permis d'identifier les principales caractĂ©ristiques qui affectent la performance de la communication pendant le transfert massif et parallĂšle de donnĂ©es. Ces caractĂ©ristiques sont liĂ©es Ă  des paramĂštres qui dĂ©crivent les interactions entre l'application et les ressources de l'infrastructure, en termes de capacitĂ©, de disponibilitĂ© et d’utilisation

    Electromagnetic Simulations via Parallel Computing: an Application Using Scale Changing Technique of Passive Planar Reflectarrays in Grid Environment

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    International audienceElectromagnetic simulation continues to be the primary method by which engineers and researchers analyze and design circuits and systems. Nowadays, the complexification related to the rise of microwaves circuits results in the coexistence of several scales in the same circuit and in the appearance of important dimensions ratios. As the dimensions of modern Electromagnetic circuits continue to shrink, the fabrication and parametric testing of such structures have become more challenging. Increasing market pressures are driving engineers and researchers to minimize the time-to-the-market. So more efficient simulation strategies to accelerate the simulation process are required. Parallel and distributed simulation approaches seem to be a promising approach in this direction. With the growing incidence of computer modeling and simulation, the scope of this paper is to show that parallel simulation of multi-scale models can achieve several orders of magnitude speedup. When mapped onto distributed memory multicomputer systems like Computational Grid, additional speedup is obtained

    Application of Scale Changing Technique - Grid Computing to the Electromagnetic Simulation of Reflectarrays

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    National audienceIn the field of high frequency communications, in order to provide better communication bandwidth, a reflectarray antenna is employed to receive and send signals. Large reflectarray geometries analysis demand significant computational resources if one want to use existing full-wave approaches. In this paper, we demonstrate capability of the Scale Changing Technique (SCT) [1] in designing reflectarray antennas having enormous finite number of non-uniform radiating elements with high scale ratios in a given band. We propose the use of parallel advantages of SCT for the electromagnetic simulation of reflectarrays in a grid computing environment. System partitioning and parallel solution methods, as well as parametric studies are described. In order to demonstrate the feasibility and to assess the performance of the proposed techniques, a parallel electromagnetic program for a grid environment has been developed. Tests using arrays of different sizes, executed on Grid'5000 [2] computing nodes, have shown very promising performance indices
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