858 research outputs found
Smooth free involution of and Smith conjecture for imbeddings of in
This paper establishes an equivalence between existence of free involutions
on and existence of involutions on with fixed point set an
imbedded , then a family of counterexamples of the Smith conjecture for
imbeddings of in are given by known result on . In
addition, this paper also shows that every smooth homotopy complex projective
3-space admits no orientation preserving smooth free involution, which answers
an open problem [Pe]. Moreover, the study of existence problem for smooth
orientation preserving involutions on is completed.Comment: 10 pages, final versio
Western oceanus procellarum as seen by c1xs on chandrayaan-1
We present the analysis of an X-ray fluorescence (XRF) observation of the western part of Oceanus Procellarum on the Moon’s nearside made by the Chandrayaan-1 X-ray Spectrometer on 10th February 2009. Through forward modelling of the X-ray spectra, we provide estimates of the MgO/SiO2 and Al2O3/SiO2 ratios for seven regions along the flare’s ground track. These results are combined with FeO and TiO2 contents derived from Clementine multispectral reflectance data in order to investigate the compositional diversity of this region of the Moon. The ground track observed consists mainly of low-Ti basaltic units, and the XRF data are largely consistent with this expectation. However, we obtain higher Al2O3/SiO2 ratios for these units than for most basalts in the Apollo sample collection. The widest compositional variation between the different lava flows is in wt% FeO content. A footprint that occurs in a predominantly highland region, immediately to the north of Oceanus Procellarum, has a composition that is consistent with mixing between low-Ti mare basaltic and more feldspathic regoliths. In contrast to some previous studies, we find no evidence for systematic differences in surface composition, as determined through X-ray and gamma-ray spectroscopy techniques
P-wave excited baryons from pion- and photo-induced hyperon production
We report evidence for , , ,
, , and , and find
indications that might have a companion state at 1970\,MeV. The
controversial is not seen. The evidence is derived from a
study of data on pion- and photo-induced hyperon production, but other data are
included as well. Most of the resonances reported here were found in the
Karlsruhe-Helsinki (KH84) and the Carnegie-Mellon (CM) analyses but were
challenged recently by the Data Analysis Center at GWU. Our analysis is
constrained by the energy independent scattering amplitudes from either
KH84 or GWU. The two amplitudes from KH84 or GWU, respectively, lead to
slightly different branching ratios of contributing resonances but the
debated resonances are required in both series of fits.Comment: 22 pages, 28 figures. Some additional sets of data are adde
Integrating fluctuations into distribution of resources in transportation networks
We propose a resource distribution strategy to reduce the average travel time
in a transportation network given a fixed generation rate. Suppose that there
are essential resources to avoid congestion in the network as well as some
extra resources. The strategy distributes the essential resources by the
average loads on the vertices and integrates the fluctuations of the
instantaneous loads into the distribution of the extra resources. The
fluctuations are calculated with the assumption of unlimited resources, where
the calculation is incorporated into the calculation of the average loads
without adding to the time complexity. Simulation results show that the
fluctuation-integrated strategy provides shorter average travel time than a
previous distribution strategy while keeping similar robustness. The strategy
is especially beneficial when the extra resources are scarce and the network is
heterogeneous and lowly loaded.Comment: 14 pages, 4 figure
Interatomic potentials for atomistic simulations of the Ti-Al system
Semi-empirical interatomic potentials have been developed for Al, alpha-Ti,
and gamma-TiAl within the embedded atomic method (EAM) by fitting to a large
database of experimental as well as ab-initio data. The ab-initio calculations
were performed by the linear augmented plane wave (LAPW) method within the
density functional theory to obtain the equations of state for a number of
crystal structures of the Ti-Al system. Some of the calculated LAPW energies
were used for fitting the potentials while others for examining their quality.
The potentials correctly predict the equilibrium crystal structures of the
phases and accurately reproduce their basic lattice properties. The potentials
are applied to calculate the energies of point defects, surfaces, planar faults
in the equilibrium structures. Unlike earlier EAM potentials for the Ti-Al
system, the proposed potentials provide reasonable description of the lattice
thermal expansion, demonstrating their usefulness in the molecular dynamics or
Monte Carlo studies at high temperatures. The energy along the tetragonal
deformation path (Bain transformation) in gamma-TiAl calculated with the EAM
potential is in a fairly good agreement with LAPW calculations. Equilibrium
point defect concentrations in gamma-TiAl are studied using the EAM potential.
It is found that antisite defects strongly dominate over vacancies at all
compositions around stoichiometry, indicating that gamm-TiAl is an antisite
disorder compound in agreement with experimental data.Comment: 46 pages, 6 figures (Physical Review B, in press
Kinetic Turbulence
The weak collisionality typical of turbulence in many diffuse astrophysical
plasmas invalidates an MHD description of the turbulent dynamics, motivating
the development of a more comprehensive theory of kinetic turbulence. In
particular, a kinetic approach is essential for the investigation of the
physical mechanisms responsible for the dissipation of astrophysical turbulence
and the resulting heating of the plasma. This chapter reviews the limitations
of MHD turbulence theory and explains how kinetic considerations may be
incorporated to obtain a kinetic theory for astrophysical plasma turbulence.
Key questions about the nature of kinetic turbulence that drive current
research efforts are identified. A comprehensive model of the kinetic turbulent
cascade is presented, with a detailed discussion of each component of the model
and a review of supporting and conflicting theoretical, numerical, and
observational evidence.Comment: 31 pages, 3 figures, 99 references, Chapter 6 in A. Lazarian et al.
(eds.), Magnetic Fields in Diffuse Media, Astrophysics and Space Science
Library 407, Springer-Verlag Berlin Heidelberg (2015
Removal of 2-butoxyethanol gaseous emissions by biotrickling filtration packed with polyurethane foam
The removal of 2-butoxyethanol from gaseous emissions was studied using two biotrickling filters (BTF1 and BTF2) packed with polyurethane foam. Two different inoculum sources were used: a pure culture of Pseudomonas sp. BOE200 (BTF1) and activated sludge from a municipal wastewater treatment plant (BTF2). The bioreactors were operated at inlet loads (ILs) of 130 and 195 g m−3 hour−1 and at an empty bed residence time (EBRT) of 12.5 s. Under an IL of ∼130 g m−3 hour−1, BTF1 presented higher elimination capacities (ECs) than BTF2, with average values of 106 ± 7 and 68 ± 8 g m−3 hour−1, respectively. However, differences in ECs between BTFs were decreased by reducing the irrigation intervals from 1 min every 12 min to 1 min every 2 hours in BTF2. Average values of EC were 111 ± 25 and 90 ± 7 g m−3 hour−1 for BTF1 and BTF2, respectively, when working at an IL of ∼195 g m−3 hour−1. Microbial analysis revealed a significant shift in the microbial community of BTF1 inoculated with Pseudomonas sp. BOE200. At the end of the experiment, the species Microbacterium sp., Chryseobacterium sp., Acinetobacter sp., Pseudomonas sp. and Mycobacterium sp. were detected. In BTF2 inoculated with activated sludge, the denaturing gradient gel electrophoresis (DGGE) technique showed a diverse microbial community including species that was able to use 2-butoxyethanol as its carbon source, such as Pseudomonas aeruginosa and Pseudomonas putida as representative species. Although BTF1 inoculated with Pseudomonas sp. BOE200 and higher gas velocity (probably greater gas/liquid mass transfer rate) showed a slight improvement in performance, the use of activated sludge as inoculum seems to be a more feasible option for the industrial application of this technology
SARS-CoV-2 infection causes dopaminergic neuron senescence
COVID-19 patients commonly present with signs of central nervous system and/or peripheral nervous system dysfunction. Here, we show that midbrain dopamine (DA) neurons derived from human pluripotent stem cells (hPSCs) are selectively susceptible and permissive to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. SARS-CoV-2 infection of DA neurons triggers an inflammatory and cellular senescence response. High-throughput screening in hPSC-derived DA neurons identified several FDA-approved drugs that can rescue the cellular senescence phenotype by preventing SARS-CoV-2 infection. We also identified the inflammatory and cellular senescence signature and low levels of SARS-CoV-2 transcripts in human substantia nigra tissue of COVID-19 patients. Furthermore, we observed reduced numbers of neuromelanin+ and tyrosine-hydroxylase (TH)+ DA neurons and fibers in a cohort of severe COVID-19 patients. Our findings demonstrate that hPSC-derived DA neurons are susceptible to SARS-CoV-2, identify candidate neuroprotective drugs for COVID-19 patients, and suggest the need for careful, long-term monitoring of neurological problems in COVID-19 patients.</p
SARS-CoV-2 infection causes dopaminergic neuron senescence
COVID-19 patients commonly present with signs of central nervous system and/or peripheral nervous system dysfunction. Here, we show that midbrain dopamine (DA) neurons derived from human pluripotent stem cells (hPSCs) are selectively susceptible and permissive to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. SARS-CoV-2 infection of DA neurons triggers an inflammatory and cellular senescence response. High-throughput screening in hPSC-derived DA neurons identified several FDA-approved drugs that can rescue the cellular senescence phenotype by preventing SARS-CoV-2 infection. We also identified the inflammatory and cellular senescence signature and low levels of SARS-CoV-2 transcripts in human substantia nigra tissue of COVID-19 patients. Furthermore, we observed reduced numbers of neuromelanin+ and tyrosine-hydroxylase (TH)+ DA neurons and fibers in a cohort of severe COVID-19 patients. Our findings demonstrate that hPSC-derived DA neurons are susceptible to SARS-CoV-2, identify candidate neuroprotective drugs for COVID-19 patients, and suggest the need for careful, long-term monitoring of neurological problems in COVID-19 patients.</p
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