Organization of Accounting Documents Flow in Company by Use the Information Systems

Tato bakalářská práce se zabývá analýzou a návrhem změn informačního systému vedoucí ke zlepšení organizace oběhu účetních dokladů v podniku. Popisuje základní teoretické poznatky o oběhu účetních dokladů a analyzuje stav stávajícího informačního systému v podniku C SYSTEM, a.s. Návrhová část bakalářské práce je zaměřena na možnost implementace elektronické výměny dat do stávajícího informačního systému podniku a tím na zefektivnění práce s účetními doklady.This Bachelor thesis concerns with the analysis and design of information system changes to improve the accounting documents flow in the company. It describes the basic theoretical knowledge of the accounting documents flow and analysis current situation of information system in the C SYSTEM company. The design part of Bachelor thesis is aiming to the possibility of implementation of electronic data interchange to the existing information system and makes work with accounting documents more efficient.

Evaluation of the Performance of the Company by Using of Information Systems

Diplomová práce se zabývá hodnocení ekonomické výkonnosti společnosti C SYSTEM CZ a.s. v letech 2009 až 2013. V teoretické části jsou popsány základní metody finanční analýzy a strategického přístupu k hodnocení výkonnosti, na které navazuje analýza vývoje zmíněného podniku z pohledu finančních ukazatelů a postavení na trhu. Návrhová část je zaměřena na využití vnitropodnikového informačního systému jako nástroje pro zprostředkování vybraných výsledků finanční analýzy za účelem reportování a porovnávání s konkurencí.This Diploma thesis deals with evaluation of the economic performance of the company C SYSTEM CZ a.s. in years 2009 – 2013. In theoretical part is described methodology of financial analyses and strategic approach to evaluation of the company which is followed by financial analyses of the chosen company in terms of financial indicators and market position. Practical part is focused on using of the information system as a tool to mediate chosen results of the financial analysis for reporting and benchmarking.

Ozone treatment of stored potato tubers

During storage, potato tubers are susceptible to different pathogen, which can attack the skin and flesh of the tubers. The most serious damage can be caused by rot inducing bacteria and fungi. A possible way to prevent microbial damage may be the use of ozone in the air ventilated through the stored tubers. However, the tubers can undergo qualitative changes, e.g. dehydration and loss of starch content. This article presents the results of a five-month experiment in which ozone concentration of 5 mg m-3 was periodically introduced in some of the stored potato tubers of the cultivar ‘Dali’. All potato tubers were stored in closed storage boxes with a metal frame and wood panels in the floor and walls (ground area 1.6×1.2 m, height 0.95 m) which were continuously aerated using the ambient air in a potato warehouse. There was 900 kg of tubers stored in the box. At the end of the experiment, the ozonated variant was compared with the control (not treated). The ozone-treated tubers had 2.95 times lower incidence of infection by rot and the number of microorganisms on healthy tubers was lower than the control. The ozone-treated tubers were less frequently dehydrated. The water loss was higher in control by 0.86 %. There was no significant difference in silver scurf manifestation or in the starch content between the two variants

Real-Life Report on Chemoembolization Using DEBIRI for Liver Metastases from Colorectal Cancer

Background. Transarterial chemoembolization (TACE) has been investigated in patients with liver metastases from colorectal cancer (LMCRC). Limited experience and available data suggest that TACE can achieve disease stabilization or improvement, even in heavily pretreated patients. Methods. Patients with LMCRC, ECOG 0–2, who failed at least 1 line of systemic chemotherapy, received embolizations with 2 mL of microspheres preloaded with 100 mg of irinotecan. Beads were delivered selectively into hepatic arteries. Primary endpoint was overall survival (OS), analyzed using the Kaplan-Meier method. Secondary endpoint was safety, assessed using CTCAE version 4.0. Results. 27 patients were treated using DEBIRI. Patient median age was 57 years (range was 45–82 years). The median number of total embolizations was 1.3 (range 1–3). The median OS was 5.4 months (95% CI; 1.1–22.7 months). The most reported postembolization events were nausea (8/27), vomiting (6/27), right upper quadrant pain (16/27), fatigue (9/27), and the development of ascites (6/27). 5/26 patients required hospitalization after TACE for severe pain. Hospitalization was also required for 1 case of allergic reaction and 1 case of infection. Conclusion. Our data suggest that TACE with DEBIRI could be efficacious in a palliative setting for patients with LMCRC, but they do not necessarily support routine use in clinical practice

Longitudinal study to assess changes in arterial stiffness and cardiac output parameters among low-risk pregnant women.

AIM: A single-centre, prospective longitudinal study to assess changes in maternal arterial stiffness and cardiac output parameters among low-risk healthy pregnant women. METHODOLOGY: Thirty low-risk, healthy, pregnant women attending their routine antenatal dating ultrasound scan were recruited. Non-invasive assessment of arterial stiffness and cardiac output was undertaken at five gestational windows from 11 to 40 weeks of pregnancy. Data were analysed using a linear mixed model incorporating time and other relevant predictors as fixed effects, and patient as a random effect. RESULTS: Gestational age had a significant effect on all arterial stiffness parameters, including brachial augmentation index (AIx) (p = .001), aortic AIx (p = .002) and aortic pulse wave velocity (p = .002). The aortic AIx (%) reduced during pregnancy: the lowest mean (standard error, SE) was 4.07 (1.01) at 28 weeks before it increased to 7.04 (SE 1.64) at 40 weeks. Similarly, non-invasive assessments of cardiac output (p < .001), stroke volume (p = .014), heart rate (p < .001) and total peripheral resistance (p < .001) demonstrated significant changes with gestational age. Mean cardiac output (l/m) increased during pregnancy reaching a peak at 28 weeks gestation 6.66 (SE 0.28), but dropped thereafter to reach 5.71 (SE 0.25) around term. CONCLUSION: The current study provides pregnancy normograms for gestational changes in arterial stiffness and cardiac output parameters among low-risk, healthy pregnant women. Further work will be required to assess the risk of placental mediated diseases and pregnancy outcome among pregnant women with parameters outside the normal range

HUBUNGAN RENTANG LENGAN DENGAN SERVIS BAWAH BOLA VOLI PADA SISWA PUTERA EKSTRAKURIKULER SMA NEGERI 5 KOTA LANGSA TAHUN PELAJARAN 2013/2014

Banda Ace

Assessment of arterial function in pregnancy: recommendations of the International Working Group on Maternal Haemodynamics.

There is strong evidence supporting a role of maternal arterial dysfunction in pregnancy-specific disorders such as pre-eclampsia and intra-uterine growth restriction. As more work is focused towards this field, it is important that methods and interpretation of arterial function assessment are utilised appropriately. Here, we summarise techniques and devices commonly used in maternal health studies, with considerations of technical application within pregnant cohorts

Syncytiotrophoblast derived extracellular vesicles transfer functional placental miRNAs to primary human endothelial cells

During the pregnancy associated syndrome preeclampsia (PE), there is increased release of placental syncytiotrophoblast extracellular vesicles (STBEVs) and free foetal haemoglobin (HbF) into the maternal circulation. In the present study we investigated the uptake of normal and PE STBEVs by primary human coronary artery endothelial cells (HCAEC) and the effects of free HbF on this uptake. Our results show internalization of STBEVs into primary HCAEC, and transfer of placenta specific miRNAs from STBEVs into the endoplasmic reticulum and mitochondria of these recipient cells. Further, the transferred miRNAs were functional, causing a down regulation of specific target genes, including the PE associated gene fms related tyrosine kinase 1 (FLT1). When co-treating normal STBEVs with HbF, the miRNA deposition is altered from the mitochondria to the ER and the cell membrane becomes ruffled, as was also seen with PE STBEVs. These findings suggest that STBEVs may cause endothelial damage and contribute to the endothelial dysfunction typical for PE. The miRNA mediated effects on gene expression may contribute to the oxidative and endoplasmic reticulum stress described in PE, as well as endothelial reprogramming that may underlay the increased risk of cardiovascular disease reported for women with PE later in life

A cohort evaluation on arterial stiffness and hypertensive disorders in pregnancy

10.1186/1471-2393-12-160BMC Pregnancy and Childbirth12-BPCM