35 research outputs found

    瀬戸内国際芸術祭2013 沙弥島アートプロジェクト by 神戸芸術工科大学

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    本稿は、瀬戸内国際芸術祭2013 春の部(2013年3月20日[春分の日]~4月21日[日])の一環として参加した「沙弥島アートプロジェクト by 神戸芸術工科大学」で行われた全ての活動について、成果物の画像を交えながらその内容を述べたものである。成果物として挙げられるのは、次の4つ、①香川県坂出市沙弥島内3カ所(西ノ浜、ナカンダ浜、旧沙弥小中学校)を舞台にした本学の教員(助手・実習助手含む)6名による作品展示・建築作品の公開、②準備期間中に行った地元の子供・親子を対象にしたワークショップ、③会期中に行った一般客及び地元住人を対象にしたイベント、④大学院の選択科目のひとつである大学院総合プロジェクト「沙弥島アートプロジェクト」において、担当教員の指導のもと、学生が行ったポスターや周辺地図などの印刷物およびスタッフ用パーカーなどのグッズ企画・制作である。This report assesses all the activities carried out in ‘Shamijima Art Project by Kobe Design University’ which was held as a part of Setouchi Triennale 2013 Spring term (20th March and 21st April 2013), together with the images of the project outcomes. The following four types of work have been completed in the project; ① Works of art and architecture created by six teachers of KDU(including assistants and a research assistant) in three different venues (Nishinohama Beach, Nakandahama Beach and Fomer-Shami Elementary and Junior High School), ②Workshops for the local people held in the preparation period, ③ Events for both the local and general visitors during the Triennale period, and ④ Poster, map and other graphic design works and goods productions such as staff costume created by students under the supervision in the one of the Kobe Design University graduate school’s optional subjects which is also called ‘Shamijima Art Project’

    アートプロジェクトによるコミュニティ生成/瀬戸内国際芸術祭2013、沙弥島アートプロジェクトの実践による研究

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    2013 年、第2 回「瀬戸内国際芸術祭2013」が開催され、本学でも香川県坂出市沙弥島を会場とする「沙弥島アートプロジェクト by 神戸芸術工科大学」として参加した。このプロジェクトは2013 年3 月20 日から4 月21 日を会期としたもので、全容は昨年の紀要「芸術工学2013」において報告したが、沙弥島を対象とした研究は継続して行われ、秋季には「沙弥島・あの感動を再び」と題して、独自の展覧会を行った。プロジェクトは2012 年度と13 年度をまたいで実践されることになったが、2013 年度共同研究としての位置づけとしては、春季開催中の会場運営、夏期芸術祭期間の他会場での開催プロジェクトとの比較考察、秋季展覧会の企画・実践を担っている。また、この2013 年の成果をもとに沙弥島でのプロジェクトは2014 年度も継続することが決定している。‘Shamijima Art Project by Kobe Design University’ was held as a part of Setouchi Triennale 2013 Spring term (20th March to 21st April 2013). Complete works of the spring term project were reported on bulletin of last year ‘2013’. Since then the project was continued under the subvention of the University.In the summer term of the Trinnale, some member of research inspect the another area of Setouchi and consider the way of community formation by arts or architectural design.In autumn, we planned a second exhibition and workshop titled ‘we remember the Shamijima’. The main subject of the show is retrospect of spring term project. But then two particular programs are executed. ‘Possible futures Sakaide’ show the fictional cityscape. These works are represented by high-school students of Sakaide city. At the workshop for children, salt and shell of Shami-beach is the matter.At present, Shamijima Art Project progress to 2014’s new program

    Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

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    Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Novel SPEG variants in a neonate with severe dilated cardiomyopathy and relatively mild hypotonia

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    Abstract Striated muscle preferentially expressed protein kinase (SPEG) variants have been reported to cause centronuclear myopathy associated with cardiac diseases. The severity of skeletal muscle symptoms and cardiac symptoms are presumably related to the location of the variant. Here, we report novel SPEG compound heterozygous pathological variants in a neonate with severe dilated cardiomyopathy and relatively mild hypotonia. This report expands the genotype-phenotype correlations of patients with SPEG variants
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