5,711 research outputs found
Integral transformation solution of free-space cylindrical vector beams and prediction of modified-Bessel-Gaussian vector beams
A unified description of the free-space cylindrical vector beams is
presented, which is an integral transformation solution to the vector Helmholtz
equation and the transversality condition. The amplitude 2-form of the angular
spectrum involved in this solution can be arbitrarily chosen. When one of the
two elements is zero, we arrive at either transverse-electric or
transverse-magnetic beam mode. In the paraxial condition, this solution not
only includes the known Bessel-Gaussian vector beam and the axisymmetric
Laguerre-Gaussian vector beam that were obtained by solving the paraxial wave
equations, but also predicts two new kinds of vector beam, called the
modified-Bessel-Gaussian vector beam.Comment: 8 pages and 1 figur
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Towards sarcosine determination in urine for prostatic carcinoma detection
Sarcosine, a potential biomarker for prostate cancer, can be detected in a solid state enzyme based biosensor using sarcosine oxidase, with particle immobilised reagents. A novel fusion protein of the fluorescent protein, mCherry, sarcosine oxidase (SOx), and the polypeptide R5 (R52-mCherry-SOx-R5-6H), was explored, which allowed self-immobilization on silica microparticles and long-term (90 days +) retention of activity, even at room temperature. In contrast, commercial wildtype SOx lost activity in a few days. A silica-R52-mCherry-SOx-R5-6H microparticle sensor for determination of sarcosine in urine, linked the SOx coproduct, H2O2, to a measurement catalysed by horseradish peroxidase (HRP) immobilised on silica, in the presence of Amplex Ultrared (AR) to generate fluorescence at 582 nm. Silica microparticles carrying all the reagents (R52-mCherry-SOx-R5-6H, HRP and AR) were used to produce a silica-microparticle biosensor which responded to sarcosine at micromolar levels. Interference by amino acids and uric acid was examined and it was found that the silica-reagent carrying system could be calibrated in urine and responded across the clinically relevant concentration range. This contrasted with similar assays using commercial SOx, where interference inhibited the sarcosine signal measurement in urine. The microparticle biosensor was tested in urine from healthy volunteers and prostate cancer patients, showing higher concentrations of sarcosine in cancer patients consistent with previous reports of elevated sarcosine levels.BBSRC/EPSRC funded Grant No. BB/L014130/1
Gates Cambridge Trust
Generalitat Valenciana and European commission for its postdoctoral grant (APOSTD/113/2016)
Generalitat Valenciana (PROMETEO 2016/109
Modeled climate change effects on distributions of Canadian butterfly species
Abstract: Climate change effects on biodiversity are being documented now frequently in the form of changes in
phenology and distributional shifts. However, the form that these effects will take over a longer timespan is unclear; for
this understanding, a quantitative, validated, predictive approach is key. Here, we use ecological niche modeling and
general circulation model outputs to estimate future potential geographic distributions of 111 Canadian butterfly species.
We develop future estimates under two emission scenarios from each of two climate change modeling centers; future
projections for biodiversity are not only scenario dependent (more severe emission scenarios produce more severe
effects on speciesâ distributions) but also model dependent (the Canadian Centre for Climate Modelling and Analysis
results were more severe than the Hadley Centre results). One interesting feature is the appearance of disjunctions in
speciesâ distributions, hence creating âvicariant eventsâ over very short time periods. In general, however, a cost of
1%â3% additional loss of speciesâ distributions is associated with more severe scenarios of emissions and climate
change, suggesting that subtle biodiversity consequences are associated with the different climate futures debated in
political circles.
Résumé : La littérature scientifique courante traite fréquemment des effets des changements climatiques sur la biodiversité,
particuliÚrement en ce qui a trait aux changements phénologiques et aux modifications des répartitions géographiques.
Cependant, la forme que prendront ces effets sur une échelle temporelle plus longue reste à préciser, car pour
ce faire il est nĂ©cessaire dâavoir recours Ă une approche quantitative, validĂ©e et prĂ©dictive. Les rĂ©sultats dâune modĂ©lisation
de la niche écologique et de modÚles de circulation générale nous ont servi à estimer la répartition géographique
potentielle future de 111 espÚces de papillons canadiens. Nous avons basé nos prédictions sur deux scénarios
dâĂ©missions provenant de deux centres de modĂ©lisation du climat; ces prĂ©dictions de la biodiversitĂ© dĂ©pendent non seulement
du scĂ©nario choisi (les scĂ©narios dâĂ©missions plus importantes produisent des effets plus marquĂ©s sur la rĂ©partition
des espĂšces), mais aussi du modĂšle retenu (les rĂ©sultats du Centre canadien pour la modĂ©lisation et lâanalyse du
climatique sont plus rigoureux que ceux du Centre Hadley). Une caractĂ©ristique intĂ©ressante est lâapparition de fragmentations
dans la répartition des espÚces, ce qui crée des « événements de vicariance » sur de trÚs courtes périodes.
En gĂ©nĂ©ral, cependant, un coĂ»t de 1 % â 3 % en perte additionnelle dans les rĂ©partitions accompagne les scĂ©narios les
plus rigoureux de changement climatique, ce qui indique que les conséquences sur la biodiversité des divers scénarios
climatiques futurs discutés dans les milieux politiques sont assez subtiles.
[Traduit par la RĂ©daction
Family Involvement in Management and Product Innovation: The Mediating Role of R&D Strategies
Following calls to capture family firmsâ innovative behavior and to specifically clarify how family firms manage product innovations to achieve sustainable economic development, this study empirically investigates the mediating role of Research & Development (R&D) strategies (i.e., intramural R&D investments, extramural R&D investments, and the combination of both intramural and extramural R&D investments) in the relationship between family involvement in the management and likelihood of obtaining product innovations. Carrying out a panel data analysis that is based on 7264 observations of Spanish manufacturing firms throughout the 2000â2015 period, our results suggest a negative effect of the level of family management on the likelihood of introducing product innovations. Moreover, we found that intramural R&D investments and the investment strategy consisting of both intramural and extramural R&D mediated the family involvement in management-likelihood of obtaining product innovations relationship. Our findings contribute important insights to the comprehension of which determinants instigate product innovation in family managed firms
Basal Chromospheric Flux and Maunder Minimum-type Stars: The quiet-Sun Chromosphere as a Universal Phenomenon
Aims: We demonstrate the universal character of the quiet-Sun chromosphere
among inactive stars (solar-type and giants). By assessing the main physical
processes, we shed new light on some common observational phenomena. Methods:
We discuss measurements of the solar Mt. Wilson S-index, obtained by the
Hamburg Robotic Telescope around the extreme minimum year 2009, and compare the
established chromospheric basal Ca II K line flux to the Mt. Wilson S-index
data of inactive ("flat activity") stars, including giants. Results: During the
unusually deep and extended activity minimum of 2009, the Sun reached S-index
values considerably lower than in any of its previously observed minima. In
several brief periods, the Sun coincided exactly with the S-indices of inactive
("flat", presumed Maunder Minimum-type) solar analogues of the Mt. Wilson
sample; at the same time, the solar visible surface was also free of any plages
or remaining weak activity regions. The corresponding minimum Ca II K flux of
the quiet Sun and of the presumed Maunder Minimum-type stars in the Mt. Wilson
sample are found to be identical to the corresponding Ca II K chromospheric
basal flux limit. Conclusions: We conclude that the quiet-Sun chromosphere is a
universal phenomenon among inactive stars. Its mixed-polarity magnetic field,
generated by a local, "fast" turbulent dynamo finally provides a natural
explanation for the minimal soft X-ray emission observed for inactive stars.
Given such a local dynamo also works for giant chromospheres, albeit on larger
length scales, i.e., l ~ R/g, with R and g as stellar radius and surface
gravity, respectively, the existence of giant spicular phenomena and the
guidance of mechanical energy toward the acceleration zone of cool stellar
winds along flux-tubes have now become traceable.Comment: 6 pages, 4 figures; Astronomy & Astrophysics (Research Note), in
pres
Fate of Irgarol 1051, diuron and their main metabolites in two UK marine systems after restrictions in antifouling paints
Two major antifouling biocides used worldwide, Irgarol 1051 and diuron, and their degradation products in Shoreham Harbour and Brighton Marina, UK were studied during 2003-2004. The highest concentrations of Irgarol 1051 were 136 and 102 ng L(-1) in water and 40 and 49 ng g(-1) dry weight in sediments for Shoreham Harbour and Brighton Marina, respectively. As the degradation product of Irgarol 1051, M1 was also widespread, with the highest concentration of 59 ng L(-1) in water and 23 ng g(-1) in sediments in Shoreham Harbour, and 37 ng L(-1) in water and 5.6 ng g(-1) in sediments in Brighton Marina. The target compounds showed enhanced concentrations during the boating season (May-July), when boats were being re-painted (January-February), and where the density of pleasure crafts was high. Overall, the concentration of Irgarol 1051 decreased significantly from late 2000 to early 2004, indicating the effectiveness of controlling its concentrations in the marine environment following restricted use. Diuron was only detected in 14% of water samples, and mostly absent from sediment samples
Chromospheric activity and rotation of FGK stars in the solar vicinity. An estimation of the radial velocity jitter
Context: Chromospheric activity produces both photometric and spectroscopic
variations that can be mistaken as planets. Large spots crossing the stellar
disc can produce planet-like periodic variations in the light curve of a star.
These spots clearly affect the spectral line profiles and their perturbations
alter the line centroids creating a radial velocity jitter that might
contaminate" the variations induced by a planet. Precise chromospheric activity
measurements are needed to estimate the activity-induced noise that should be
expected for a given star. Aims: We obtain precise chromospheric activity
measurements and projected rotational velocities for nearby (d < 25 pc) cool
(spectral types F to K) stars, to estimate their expected activity-related
jitter. As a complementary objective, we attempt to obtain relationships
between fluxes in different activity indicator lines, that permit a
transformation of traditional activity indicators, i.e, CaII H & K lines, to
others that hold noteworthy advantages. Methods: We used high resolution
(~50000) echelle optical spectra. To determine the chromospheric emission of
the stars in the sample, we used the spectral subtraction technique. Rotational
velocities were determined using the cross-correlation technique. To infer
activity-related radial velocity (RV) jitter, we used empirical relationships
between this jitter and the R'_HK index. Results: We measured chromospheric
activity, as given by different indicators throughout the optical spectra, and
projected rotational velocities for 371 nearby cool stars. We have built
empirical relationships among the most important chromospheric emission lines.
Finally, we used the measured chromospheric activity to estimate the expected
RV jitter for the active stars in the sample.Comment: Accepted for publication in Astronomy & Astrophysic
Equation of state and transport processes in self--similar spheres
We study the effect of transport processes (diffusion and free--streaming) on
a collapsing spherically symmetric distribution of matter in a self--similar
space--time. A very simple solution shows interesting features when it is
matched with the Vaidya exterior solution. In the mixed case (diffusion and
free--streaming), we find a barotropic equation of state in the stationary
regime. In the diffusion approximation the gravitational potential at the
surface is always constant; if we perturb the stationary state, the system is
very stable, recovering the barotropic equation of state as time progresses. In
the free--streaming case the self--similar evolution is stationary but with a
non--barotropic equation of state.Comment: 9 pages, 2 figure
Global environmental changes: setting priorities for Latin American coastal habitats.
The definitive version is available at www.blackwell-synergy.comThe Intergovernmental Panel for Climate Change (IPCC) reports that Global Environmental Changes (GEC) are occurring quicker than at any other time over the last 25 million years and impacting upon marine environments (Bellard et al., 2012). There is overwhelming evidence showing that GEC are affecting both the quality and quantity of the goods and services provided by a wide range of marine ecosystems. In order to discuss regional preparedness for global environmental changes, a workshop was held in Ilhabela, Brazil (22- 26 April 2012) entitled "Evaluating the Sensitivity of Central and South American Benthic Communities to Global Environmental Changes" that drew together scientists from ten Latin American and three European countries. © 2013 Blackwell Publishing Ltd
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