Polymer dynamics, fluorescence correlation spectroscopy, and the limits of optical resolution

In recent years, fluorescence correlation spectroscopy has been increasingly applied for the study of polymer dynamics on the nanometer scale. The core idea is to extract, from a measured autocorrelation curve, an effective mean-square displacement function that contains information about the underlying conformational dynamics. The paper presents a fundamental study of the applicability of fluorescence correlation spectroscopy for the investigation of nanoscale conformational and diffusional dynamics. We find that fluorescence correlation spectroscopy cannot reliably elucidate processes on length scales much smaller than the resolution limit of the optics used and that its improper use can yield spurious results for the observed dynamics.Comment: 4 pages, 4 figures, accepted by Physical Review Letter

The EMU Stability and Growth Pact: Is it dead? If so, does it matter?

IN DECEMBER 2004, the new Barroso Commission brought the saga of the French and German infringements of the Stability and Growth Pact to a close by lifting the "excessive deficit" procedure launched in 2003. That same month, the Commission launched infringement proceedings against Greece that has been providing inaccurate public deficit statistics since the creation of the Pact in 1997. The new head of the Commission also declared that there would be no major overhaul of the Pact. In the November 2003 crisis, when the Council suspended the implementation of the Pact at a time France and Germany overshot its deficit ceiling, most observers called the Pact dead and many rejoiced since the Stability and Growth Pact had come under heavy criticism for some time. A year after, we asked four leading scholars that have studied monetary integration: have news of the death of the Stability and Growth pact been grossly exaggerated? Should it be resuscitated? Why or why not? Amy Verdun and Nicolas Jabko argue that the Pact will survive for lack of an alternative able to gather the support of a large bipartisan cross-national coalition. Henrik Enderlein then argues that the pact should not be fixed but broken. Finally, Andrew Martin explains why the real problem does not so much lie with the Pact per se, but instead with the philosophy behind the EMU policy mix (restrictive fiscal and monetary policies). It creates vicious circles: By keeping economic growth too low the European central bank retarded the expansion of public revenue, making it more difficult to meet the Pact requirements

Single ions trapped in a one-dimensional optical lattice

We report on three-dimensional optical trapping of single ions in an optical lattice formed by two counter-propagating laser beams. We characterize the trapping parameters of the standing wave using the ion as a sensor stored in a hybrid trap consisting of a radio-frequency (rf), a dc, and the optical potential. When loading ions directly from the rf into the standing-wave trap, we observe a dominant heating rate. Monte Carlo simulations confirm rf-induced parametric excitations within the deep optical lattice as the main source. We demonstrate a way around this effect by an alternative transfer protocol which involves an intermediate step of optical confinement in a single-beam trap avoiding the temporal overlap of the standing wave and the rf field. Implications arise for hybrid (rf/optical) and pure optical traps as platforms for ultra-cold chemistry experiments exploring atom--ion collisions or quantum simulation experiments with ions, or combinations of ions and atoms.Comment: 5 pages, 4 figure

Adjusting to EMU: the impact of supranational monetary policy on domestic fiscal and wage-setting institutions

The article suggests an explanation for seemingly diverse patterns of change in domestic economic institutions following the establishment of Economic and Monetary Union (EMU). It argues that EMU participants redesigned ill-fitting domestic fiscal and wage-setting institutions in order to counter the anticipated destabilizing effects of the 'one size fits all' monetary policy of the European Central Bank (ECB). After outlining the argument, the article identifies general economic and institutional conditions that are required for the use of fiscal and wage-setting institutions as effective stabilizers in a monetary union. It then undertakes a comparative assessment to detect country-specific mismatches between anticipated needs and the available domestic economic institutions. Finally, the article surveys institutional changes in 10 member states between the mid 1990s and 2002 and shows that the observed institutional adjustments largely correspond to the expected correction of initial mismatches

The EU budget – how much scope for institutional reform?

This paper reviews current discussions on reforming the European Union (EU) budgetary procedure and assesses the main reform proposals that have been suggested thus far. It argues that prospects for reforms are presently hampered by the complex interplay between supranational and intergovernmental decision modes and the requirement of any budgetary procedure to strike a balance between efficiency and legitimacy. The paper reviews the main criticisms of the present budgetary procedure and the related reform proposals, which are assessed on the basis of relevant theoretical literature as well as brief comparisons with the federal budget of the United States. The paper argues that the current EU budgetary procedure maximises efficiency and legitimacy, given the present state of political integration in the EU. Significant modifications to the budgetary procedure would depart from that equilibrium.

Financing of the European Union Budget.

This study is concerned with the future financing of the EU budget, including possible budgetary correction mechanisms, and is intended to feed into the budget review. The revenue side of the EU budget comprises several elements, all of which need to be assessed in appraising the functioning of the current system and whether it should be reformed. They include the revenue instruments used - the ‘own resources’ (OR) - and how they are set, the means by which net contributions deemed to be excessive are adjusted, and how to ensure that the EU’s revenue balances its expenditure as required by Art. 268 TEC. Such balanced budget rules are often applied to control the expenditure of sub-national governments in multi-level fiscal systems Work done in the course of this study has included an extensive literature survey and examination of relevant previous work, empirical research and policy analysis. The empirical work comprised a mix of qualitative and quantitative analysis, extensive dialogue with practitioners, and a survey directed to officials (mainly, but by no means exclusively, in finance ministries) in Member States. This research has been used to investigate both how well the current system is working and to try to provide a systematic basis for analysing options for reform.

The EU budget – how much scope for institutional reform?

This paper reviews current discussions on reforming the European Union (EU) budgetary procedure and assesses the main reform proposals that have been suggested thus far. It argues that prospects for reforms are presently hampered by the complex interplay between supranational and intergovernmental decision modes and the requirement of any budgetary procedure to strike a balance between efficiency and legitimacy. The paper reviews the main criticisms of the present budgetary procedure and the related reform proposals, which are assessed on the basis of relevant theoretical literature as well as brief comparisons with the federal budget of the United States. The paper argues that the current EU budgetary procedure matches by-and-large the current equilibrium between all actors involved, given the present state of political integration in the EU. Significant modifications to the budgetary procedure would depart from that equilibrium.European Union, EU budget, budget process