2,559 research outputs found
Diethyl 4-(4,5-dihydrofuran-2-yl)-3,5-dimethyl-1-phenyl-1,4-dihydropyrazine-2,6-dicarboxylate
In the title compound, C22H26N2O5, the central 1,4-dihydropyrazine ring adopts a boat conformation, while the benzene ring and the two disordered components of the furan ring are inclined at angles of 77.9 (5) and 61.9 (7)°. Three of the C atoms of the furan ring are disordered over two positions with occupancies of 0.655 (18) and 0.345 (18). In the crystal structure, weak intermolecular C—H⋯O hydrogen bonds link the molecules into chains propagating in [010]
Center or Limit Cycle: Renormalization Group as a Probe
Based on our studies done on two-dimensional autonomous systems, forced
non-autonomous systems and time-delayed systems, we propose a unified
methodology - that uses renormalization group theory - for finding out
existence of periodic solutions in a plethora of nonlinear dynamical systems
appearing across disciplines. The technique will be shown to have a non-trivial
ability of classifying the solutions into limit cycles and periodic orbits
surrounding a center. Moreover, the methodology has a definite advantage over
linear stability analysis in analyzing centers
Turning ABO antiferroelectrics into ferroelectrics: Design rules for practical rotation-driven ferroelectricity in double perovskites and ABO Ruddlesden-Popper compounds
Ferroic transition metal oxides, which exhibit spontaneous elastic,
electrical, magnetic or toroidal order, exhibit functional properties that find
use in ultrastable solid-state memories to sensors and medical imaging
technologies. To realize multifunctional behavior, where one order parameter
can be coupled to the conjugate field of another order parameter, however,
requires a common microscopic origin for the long-range order. Here, we
formulate a complete theory for a novel form of ferroelectricity, whereby a
spontaneous and switchable polarization emerges from the destruction of an
antiferroelectric state due to octahedral rotations and ordered cation
sublattices. We then construct a materials design framework based on
crystal-chemistry descriptors rooted in group theory, which enables the facile
design of artificial oxides with large electric polarizations, P, simultaneous
with small energetic switching barriers between +P and -P. We validate the
theory with first principles density functional calculations on more than 16
perovskite-structured oxides, illustrating it could be operative in any
materials classes exhibiting two- or three-dimensional corner-connected
octahedral frameworks. We show the principles governing materials selection of
the "layered" systems originate in the lattice dynamics of the A cation
displacements stabilized by the pervasive BO rotations of single phase
ABO materials, whereby the latter distortions govern the optical band gaps,
magnetic order and critical transition temperatures. Our approach provides the
elusive route to the ultimate multifunctionality property control by an
external electric field.Comment: 13 pages, 11 figure
Fourth generation effects in rare exclusive B -> K^* l^+ l^- decay
Influence of the fourth generation, if ever exists, on the experimentally
measurable quantities such as invariant dilepton mass distribution, lepton
forward-backward asymmetry, and the ratio (Gamma_L/Gamma_T) of the decay widths
when K* meson is longitudinally and transversally polarized, is studied. Using
the experimental results on the branching ratios for the (B -> X_s) gamma and
semileptonic (B -> X_c l nu) decays, the two possible solutions of the 4x4
Cabibbo-Kobayashi-Maskawa factor (V_{t's} V_{t^'b}) are obtained as a function
of the t'-quark mass. It is observed that the results for the above-mentioned
physical quantities are essentially different from the standard model
predictions only for one solution of the CKM factor. In this case the
above-mentioned physical quantities can serve as efficient tools in search of
the fourth generation. The other solution yields almost identical results with
the SM.Comment: 19 pages, 10 postscripted figures, LaTeX formatte
Recommended from our members
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Tobacco use is the main risk factor for HNSCC, and tobacco-associated HNSCCs have poor prognosis and response to available treatments. Recently approved anti-PD-1 immune checkpoint inhibitors showed limited activity (≤20%) in HNSCC, highlighting the need to identify new therapeutic options. For this, mouse models that accurately mimic the complexity of the HNSCC mutational landscape and tumor immune environment are urgently needed. Here, we report a mouse HNSCC model system that recapitulates the human tobacco-related HNSCC mutanome, in which tumors grow when implanted in the tongue of immunocompetent mice. These HNSCC lesions have similar immune infiltration and response rates to anti-PD-1 (≤20%) immunotherapy as human HNSCCs. Remarkably, we find that >70% of HNSCC lesions respond to intratumoral anti-CTLA-4. This syngeneic HNSCC mouse model provides a platform to accelerate the development of immunotherapeutic options for HNSCC
Synthesis of [7]phenacene incorporating tetradecyl chains in the axis positions and its application in field-effect transistors
Field-effect transistors (FETs) were fabricated using a new type of phenacene molecule, 3,12-ditetradecyl[7]phenacene ((C14H29)2-[7]phenacene), and solid gate dielectrics or an electric double layer (EDL) capacitor with an ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate (bmim[PF6])). The new molecule, (C14H29)2-[7]phenacene, was efficiently synthesized via the Mallory photoreaction. Its crystal structure and electronic properties were determined, using X-ray diffraction, scanning tunneling microscopy/spectroscopy (STM and STS), absorption spectroscopy, and photoelectron yield spectroscopy, which showed a monoclinic crystal lattice (space group P21 (no. 4)) and an energy gap of ∼3.0 eV. The STM image clearly showed the molecular structure of (C14H29)2-[7]phenacene, as well as the closed molecular stacking, indicative of a strong fastener effect between alkyl chains. The X-ray diffraction pattern of thin films of (C14H29)2-[7]phenacene formed on a SiO2/Si substrate suggested that the molecule stood on the surface with an inclined angle of 30° with respect to the normal axis of the surface. The FET properties were recorded in two-terminal measurement mode, showing p-channel normally-off characteristics. The averaged values of field-effect mobility, μ, were 1.6(3) cm2 V−1 s−1 for a (C14H29)2-[7]phenacene thin-film FET with a SiO2 gate dielectric and 6(4) × 10−1 cm2 V−1 s−1 for a (C14H29)2-[7]phenacene thin-film EDL FET with bmim[PF6]. Thus, higher FET performance was obtained with an FET using a thin film of (C14H29)2-[7]phenacene compared to parent [7]phenacene. This study could pioneer an avenue for the realization of high-performance FETs through the addition of alkyl chains to phenacene molecules
Search for radiative pumping lines of OH masers: I. The 34.6um absorption line towards 1612 MHz OH maser sources
The 1612 MHz hydroxyl maser in circumstellar envelopes has long been thought
to be pumped by 34.6um photons. Only recently, the Infrared Space Observatory
has made possible spectroscopic observations which enable the direct
confirmation of this pumping mechanism in a few cases. To look for the presence
of this pumping line, we have searched the Infrared Space Observatory Data
Archive and found 178 spectra with data around 34.6um for 87 galactic 1612MHz
masers. The analysis performed showed that the noise level and the spectral
resolution of the spectra are the most important factors affecting the
detection of the 34.6um absorption line. Only 5 objects from the sample (3 red
supergiants and 2 galactic center sources) are found to show clear 34.6um
absorption (all of them already known) while two additional objects only
tentatively show this line. The 3 supergiants show similar pump rates and their
masers might be purely radiatively pumped. The pump rates of OH masers in late
type stars are found to be about 0.05, only 1/5 of the theoretical value of
0.25 derived by Elitzur (1992). We have also found 16 maser sources which,
according to the analysis assuming Elitzur's pump rate, should show the 34.6
m absorption line but do not. These non-detections can be tentatively
explained by far-infrared photon pumping, clumpy nature of the OH masing region
or a limb-filling emission effect in the OH shell.Comment: 11 pages, 8 figures, 3 table
Intrinsic Correlation between Hardness and Elasticity in Polycrystalline Materials and Bulk Metallic Glasses
Though extensively studied, hardness, defined as the resistance of a material
to deformation, still remains a challenging issue for a formal theoretical
description due to its inherent mechanical complexity. The widely applied
Teter's empirical correlation between hardness and shear modulus has been
considered to be not always valid for a large variety of materials. Here,
inspired by the classical work on Pugh's modulus ratio, we develop a
theoretical model which establishes a robust correlation between hardness and
elasticity for a wide class of materials, including bulk metallic glasses, with
results in very good agreement with experiment. The simplified form of our
model also provides an unambiguous theoretical evidence for Teter's empirical
correlation.Comment: 10 pages, 4 figures and 3 table
- …