662 research outputs found

    Educating Future Environmental Health Professionals

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    Future environmental health problems will require a new generation of educated and trained professionals. Efforts to enhance the environmental public health workforce have been promoted by several organizations. While progress has been measured by these organizations, many environmental health academic programs are experiencing budget reductions and lower enrollments. One of the reasons for this trend is the so-called higher education crisis. We argue that training is not equivalent to education in the environmental health sciences, albeit the two terms are often used interchangeably. Organizations involved with the education, training, and credentialing of environmental health professionals must work together to ensure the viability and effectiveness of environmental health academic programs

    Impact of field number and beam angle on functional image-guided lung cancer radiotherapy planning

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    To investigate the effect of beam angles and field number on functionally-guided intensity modulated radiotherapy (IMRT) normal lung avoidance treatment plans that incorporate hyperpolarised helium-3 magnetic resonance imaging ((3)He MRI) ventilation data. Eight non-small cell lung cancer patients had pre-treatment (3)He MRI that was registered to inspiration breath-hold radiotherapy planning computed tomography. IMRT plans that minimised the volume of total lung receiving  ⩾20 Gy (V20) were compared with plans that minimised (3)He MRI defined functional lung receiving  ⩾20 Gy (fV20). Coplanar IMRT plans using 5-field manually optimised beam angles and 9-field equidistant plans were also evaluated. For each pair of plans, the Wilcoxon signed ranks test was used to compare fV20 and the percentage of planning target volume (PTV) receiving 90% of the prescription dose (PTV90). Incorporation of (3)He MRI led to median reductions in fV20 of 1.3% (range: 0.2-9.3%; p  =  0.04) and 0.2% (range: 0 to 4.1%; p  =  0.012) for 5- and 9-field arrangements, respectively. There was no clinically significant difference in target coverage. Functionally-guided IMRT plans incorporating hyperpolarised (3)He MRI information can reduce the dose received by ventilated lung without comprising PTV coverage. The effect was greater for optimised beam angles rather than uniformly spaced fields

    Electron energy loss and induced photon emission in photonic crystals

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    The interaction of a fast electron with a photonic crystal is investigated by solving the Maxwell equations exactly for the external field provided by the electron in the presence of the crystal. The energy loss is obtained from the retarding force exerted on the electron by the induced electric field. The features of the energy loss spectra are shown to be related to the photonic band structure of the crystal. Two different regimes are discussed: for small lattice constants aa relative to the wavelength of the associated electron excitations λ\lambda, an effective medium theory can be used to describe the material; however, for aλa\sim\lambda the photonic band structure plays an important role. Special attention is paid to the frequency gap regions in the latter case.Comment: 12 pages, 7 figure

    For the Progress of “Faustus and Helen”: Crane, Whitman, and the Metropolitan Progress Poem

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    This essay is meant to invigorate a critical discussion of the progress poem—a genre that, while prevalent in American literature, has been virtually ignored by critics and scholars. In lieu of tackling the genre in its entirety, a project too large for just one article, the author focuses the argument through the well-known alignment between Walt Whitman and Hart Crane on the subject of the modern city. It is through the progress poem genre that Crane and Whitman’s peculiar place in metropolitan poetics can best be understood, and it is through their poetry that scholars can begin to approach the broader issue of the progress poem’s place in American literature. Cet article vise à soulever un débat critique au sujet de la poésie du progrès, un genre courant dans la littérature étatsunienne, mais pratiquement ignoré par les critiques et les commentateurs. Plutôt que d’aborder le genre dans son entièreté – un projet qui déborde du cadre d’un article –, l’auteur resserre l’argumentation autour du parallèle bien connu entre Walt Whitman et Hart Crane concernant le traitement de la ville moderne. C’est la poésie du progrès en tant que genre qui permet le mieux de comprendre la place particulière qu’occupent ces deux auteurs dans la poésie métropolitaine, et c’est par leurs poèmes que les chercheurs peuvent aborder la question plus vaste de la place du poème sur le progrès dans la littérature étatsunienne

    Panspermia, Past and Present: Astrophysical and Biophysical Conditions for the Dissemination of Life in Space

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    Astronomically, there are viable mechanisms for distributing organic material throughout the Milky Way. Biologically, the destructive effects of ultraviolet light and cosmic rays means that the majority of organisms arrive broken and dead on a new world. The likelihood of conventional forms of panspermia must therefore be considered low. However, the information content of dam-aged biological molecules might serve to seed new life (necropanspermia).Comment: Accepted for publication in Space Science Review

    First Observation of Coherent π0\pi^0 Production in Neutrino Nucleus Interactions with Eν<E_{\nu}< 2 GeV

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    The MiniBooNE experiment at Fermilab has amassed the largest sample to date of π0\pi^0s produced in neutral current (NC) neutrino-nucleus interactions at low energy. This paper reports a measurement of the momentum distribution of π0\pi^0s produced in mineral oil (CH2_2) and the first observation of coherent π0\pi^0 production below 2 GeV. In the forward direction, the yield of events observed above the expectation for resonant production is attributed primarily to coherent production off carbon, but may also include a small contribution from diffractive production on hydrogen. Integrated over the MiniBooNE neutrino flux, the sum of the NC coherent and diffractive modes is found to be (19.5 ±\pm1.1 (stat) ±\pm2.5 (sys))% of all exclusive NC π0\pi^0 production at MiniBooNE. These measurements are of immediate utility because they quantify an important background to MiniBooNE's search for νμνe\nu_{\mu} \to \nu_e oscillations.Comment: Submitted to Phys. Lett.

    A Classification of Hyper-heuristic Approaches

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    The current state of the art in hyper-heuristic research comprises a set of approaches that share the common goal of automating the design and adaptation of heuristic methods to solve hard computational search problems. The main goal is to produce more generally applicable search methodologies. In this chapter we present and overview of previous categorisations of hyper-heuristics and provide a unified classification and definition which captures the work that is being undertaken in this field. We distinguish between two main hyper-heuristic categories: heuristic selection and heuristic generation. Some representative examples of each category are discussed in detail. Our goal is to both clarify the main features of existing techniques and to suggest new directions for hyper-heuristic research

    Spatial comparison of CT-based surrogates of lung ventilation with hyperpolarized Helium-3 and Xenon-129 gas MRI in patients undergoing radiation therapy

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    Purpose To develop and apply an image acquisition and analysis strategy for spatial comparison of CT-ventilation images with hyperpolarized gas MRI. Methods 11 lung cancer patients underwent 129Xe and 3He ventilation MRI and co-registered 1H anatomical MRI. Expiratory and inspiratory breath-hold CTs were used for deformable image registration and calculation of three CT-ventilation metrics: Hounsfield unit (CTHU), Jacobian (CTJac) and specific gas volume change (CTSGV). Inspiration CT and hyperpolarized gas ventilation MRI were registered via same-breath anatomical 1H-MRI. Voxel-wise Spearman correlation coefficients were calculated between each CT-ventilation image and its corresponding 3He/129Xe-MRI, and for the mean values in regions of interest (ROIs) ranging from fine to coarse in-plane dimensions of 5x5, 10x10, 15x15 and 20x20, located within the lungs as defined by the same-breath 1H-MRI lung mask. Correlation of 3He and 129Xe-MRI was also assessed. Results Spatial correlation of CT-ventilation against 3He/129Xe-MRI increased with ROI size. For example, for CTHU, mean±SD Spearman coefficients were 0.37±0.19/0.33±0.17 at the voxel-level and 0.52±0.20/0.51±0.18 for 20x20 ROIs, respectively. Correlations were stronger for CTHU than for CTJac or CTSGV. Correlation of 3He with 129Xe-MRI was consistently higher than either gas against CT-ventilation maps over all ROIs (p<0.05). No significant differences were observed between CT-ventilation vs 3He-MRI and CT-ventilation vs 129Xe-MRI. Conclusion Comparison of ventilation-related measures from CT and registered hyperpolarized gas MRI is feasible at a voxel level using a dedicated acquisition and analysis protocol. Moderate correlation between CT-ventilation and MRI exists at a regional level. Correlation between MRI and CT is significantly less than between 3He and 129Xe-MRI, suggesting that CT-ventilation surrogate measures may not be measuring lung ventilation alone

    On the selection of AGN neutrino source candidates for a source stacking analysis with neutrino telescopes

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    The sensitivity of a search for sources of TeV neutrinos can be improved by grouping potential sources together into generic classes in a procedure that is known as source stacking. In this paper, we define catalogs of Active Galactic Nuclei (AGN) and use them to perform a source stacking analysis. The grouping of AGN into classes is done in two steps: first, AGN classes are defined, then, sources to be stacked are selected assuming that a potential neutrino flux is linearly correlated with the photon luminosity in a certain energy band (radio, IR, optical, keV, GeV, TeV). Lacking any secure detailed knowledge on neutrino production in AGN, this correlation is motivated by hadronic AGN models, as briefly reviewed in this paper. The source stacking search for neutrinos from generic AGN classes is illustrated using the data collected by the AMANDA-II high energy neutrino detector during the year 2000. No significant excess for any of the suggested groups was found.Comment: 43 pages, 12 figures, accepted by Astroparticle Physic
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