Die quantitative Analyse von Markerproteinen im Urin Quantitative analysis of marker proteins in urine

Die Analyse von spezifischen Proteinen im zweiten Morgenurin, bezogen auf den Kreatiningehalt der Probe, erlaubt heute nicht nur den Nachweis oder den Ausschluss von Nierenerkrankungen, sondern darüber hinaus auch die Differenzierung und Verlaufskontrolle von Nephropathien. Störungen lassen sich aufgrund ihres Markerproteinprofils in solche mit hauptsächlich glomerulärem oder tubulärem Anteil und zusätzlich in weitere Untergruppen einteilen. Im Zusammenhang mit den Teststreifenresultaten kann die Quelle einer Blutung mit spezifischen Quotienten näher eingegrenzt und Kontaminationen können von tatsächlichen renalen Proteinurien unterschieden werden. Eine Plausibilitätsprüfung und Interpretation der erhaltenen Ergebnisse ist unbedingt erforderlich. Da eineVielzahl von Regeln überprüft werden muss, ist eine Berechnung und Darstellung der Ergebnisse nur mit Hilfe von wissensbasierten Systemen in Kombination mit einer grafischen Befunddarstellung sinnvol

Self-Regulation of Solar Coronal Heating Process via Collisionless Reconnection Condition

I propose a new paradigm for solar coronal heating viewed as a self-regulating process keeping the plasma marginally collisionless. The mechanism is based on the coupling between two effects. First, coronal density controls the plasma collisionality and hence the transition between the slow collisional Sweet-Parker and the fast collisionless reconnection regimes. In turn, coronal energy release leads to chromospheric evaporation, increasing the density and thus inhibiting subsequent reconnection of the newly-reconnected loops. As a result, statistically, the density fluctuates around some critical level, comparable to that observed in the corona. In the long run, coronal heating can be represented by repeating cycles of fast reconnection events (nano-flares), evaporation episodes, and long periods of slow magnetic stress build-up and radiative cooling of the coronal plasma.Comment: 4 pages; Phys. Rev. Lett., in pres

MeV magnetosheath ions energized at the bow shock

A causal relationship between midlatitude magnetosheath energetic ions and bow shock magnetic geometry was previously established for ion energy up to 200 keV e−1 for the May 4, 1998, storm event. This study demonstrates that magnetosheath ions with energies above 200 keV up to 1 MeV simply extend the ion spectrum to form a power law tail. Results of cross-correlation analysis suggest that these ions also come directly from the quasi-parallel bow shock, not the magnetosphere. This is confirmed by a comparison of energetic ion fluxes simultaneously measured in the magnetosheath and at the quasi-parallel bow shock when both regions are likely connected by the magnetic field lines. We suggest that ions are accelerated at the quasi-parallel bow shock to energies as high as 1 MeV and subsequently transported into the magnetosheath during this event

A Model for Patchy Reconnection in Three Dimensions

We show, theoretically and via MHD simulations, how a short burst of reconnection localized in three dimensions on a one-dimensional current sheet creates a pair of reconnected flux tubes. We focus on the post-reconnection evolution of these flux tubes, studying their velocities and shapes. We find that slow-mode shocks propagate along these reconnected flux tubes, releasing magnetic energy as in steady-state Petschek reconnection. The geometry of these three-dimensional shocks, however, differs dramatically from the classical two-dimensional geometry. They propagate along the flux tube legs in four isolated fronts, whereas in the two-dimensional Petschek model, they form a continuous, stationary pair of V-shaped fronts. We find that the cross sections of these reconnected flux tubes appear as teardrop shaped bundles of flux propagating away from the reconnection site. Based on this, we argue that the descending coronal voids seen by Yohkoh SXT, LASCO, and TRACE are reconnected flux tubes descending from a flare site in the high corona, for example after a coronal mass ejection. In this model, these flux tubes would then settle into equilibrium in the low corona, forming an arcade of post-flare coronal loops.Comment: 27 pages plus 16 figure

Magnetic Reynolds number dependence of reconnection rate and flow structure of the self-similar evolution model of fast magnetic reconnection

This paper investigates Magnetic Reynolds number dependence of the ``self-similar evolution model'' (Nitta et al. 2001) of fast magnetic reconnection. I focused my attention on the flow structure inside and around the reconnection outflow, which is essential to determine the entire reconnection system (Nitta et al. 2002). The outflow is consist of several regions divided by discontinuities, e.g., shocks, and it can be treated by a shock-tube approximation (Nitta 2004). By solving the junction conditions (e.g., Rankine-Hugoniot condition), the structure of the reconnection outflow is obtained. Magnetic reconnection in most astrophysical problems is characterized by a huge dynamic range of its expansion ($sim 10^7$ for typical solar flares) in a free space which is free from any influence of external circumstances. Such evolution results in a spontaneous self-similar expansion which is controlled by two intrinsic parameters: the plasma-$beta$ and the magnetic Reynolds number. The plasma-$beta$ dependence had been investigated in our previous paper. This paper newly clarifies the relation between the reconnection rate and the inflow structure just outside the Petschek-like slow shock: As the magnetic Reynolds number increases, strongly converging inflow toward the Petschek-like slow shock forms, and it significantly reduces the reconnection rate.Comment: 16 pages. to appear in ApJ (2006 Jan. 20 issue

Injection of thermal and suprathermal seed particles into coronal shocks of varying obliquity

Context. Diffusive shock acceleration in the solar corona can accelerate solar energetic particles to very high energies. Acceleration efficiency is increased by entrapment through self-generated waves, which is highly dependent on the amount of accelerated particles. This, in turn, is determined by the efficiency of particle injection into the acceleration process. Aims. We present an analysis of the injection efficiency at coronal shocks of varying obliquity.We assessed injection through reflection and downstream scattering, including the effect of a cross-shock potential. Both quasi-thermal and suprathermal seed populations were analysed. We present results on the effect of cross-field diffusion downstream of the shock on the injection efficiency. Methods. Using analytical methods, we present applicable injection speed thresholds that were compared with both semi-analytical flux integration and Monte Carlo simulations, which do not resort to binary thresholds. Shock-normal angle θBn and shock-normal velocity Vs were varied to assess the injection efficiency with respect to these parameters. Results. We present evidence of a significant bias of thermal seed particle injection at small shock-normal angles. We show that downstream isotropisation methods affect the θBn-dependence of this result. We show a non-negligible effect caused by the crossshock potential, and that the effect of downstream cross-field diffusion is highly dependent on boundary definitions. Conclusions. Our results show that for Monte Carlo simulations of coronal shock acceleration a full distribution function assessment with downstream isotropisation through scatterings is necessary to realistically model particle injection. Based on our results, seed particle injection at quasi-parallel coronal shocks can result in significant acceleration efficiency, especially when combined with varying field-line geometry

Fast magnetic reconnection in free space: self-similar evolution process

We present a new model for time evolution of fast magnetic reconnection in free space, which is characterized by self-similarity. Reconnection triggered by locally enhanced resistivity assumed at the center of the current sheet can self-similarly and unlimitedly evolve until external factors affect the evolution. The possibility and stability of this type of evolution are verified by numerical simulations in a very wide spatial dynamic range. Actual astrophysical reconnection in solar flares and geomagnetospheric substorms can be treated as an evolutionary process in free space, because the resultant scale is much larger than the initial scale. In spite of this fact, most of the previous numerical works focused on the evolutionary characters strongly affected by artificial boundary conditions on the simulation boundary. Our new model clarifies a realistic evolution for such cases. The characteristic structure around the diffusion region is quite similar to the Petschek model which is characterized by a pair of slow-mode shocks and the fast-mode rarefaction-dominated inflow. However, in the outer region, a vortex-like return flow driven by the fast-mode compression caused by the piston effect of the plasmoid takes place. The entire reconnection system expands self-similarly.Comment: 17 Pages, 17 Figure