Tierexperimentelle Untersuchungen zum Problem der Insulinresistenz bei Adipositas und Diabetes mellitus. Pathogenese des fettsüchtig-hyperglykämischen Syndroms

Peer Reviewe

Broiler pulmonary hypertension syndrome. III. Commercial broiler strains differ in their susceptibility

Broilers of 4 different commercial strains were kept during winter at an altitude of 1 350m. The birds were slaughtered at weekly intervals and their relative right ventricular mass (pulmonary arterial pressure index = API values) determined. In addition, the incidence of ascites was recorded. Two of the strains suffered high losses from ascites, while the other 2 showed a certain degree of resistance. The former 2 groups had a higher mean API and a greater percentage of high API values in clinically normal birds than the other 2 groups. The group with the lowest incidence of ascites achieved the highest mean live mass at 51 days. There was also a decrease in mean API with age in clinically normal birds. There was no difference in the incidence of ascites between males and females.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.lmchunu201

The Role of Aquaculture and Capture Fisheries in Meeting Food and Nutrition Security: Testing a Nutrition-Sensitive Pond Polyculture Intervention in Rural Zambia

This study tested the efficacy of a pond polyculture intervention with farming households in northern Zambia. Longitudinal data on fish consumption and the associated nutrient intake of households (N = 57) were collected over a six-month period (September 2019–March 2020). One group of people tested the intervention while another group that practiced monoculture tilapia farming, and a third group that did not practice aquaculture, acted as control groups. A similar quantity of fish was consumed on average; however, the associated nutrient intake differed, based on the quantity and type of species consumed, particularly for those who had access to pelagic small fish from capture fisheries. There was a decrease in fish consumption from December onward due to fisheries management restrictions. The ponds provided access to micronutrient-rich fish during this time. Pond polyculture can act as a complementary source of fish to capture fisheries that are subjected to seasonal controls, as well as to households that farm tilapia. Assessments of how aquatic foods can improve food and nutrition security often separate aquaculture and capture fisheries, failing to account for people who consume fish from diverse sources simultaneously. A nutrition-sensitive approach thus places food and nutrition security, and consumers, at the center of the analysis

Remembering Marikana: Public art intervention and the right to the city in Cape Town

This article investigates the role played by cultural initiatives in urban struggles in South Africa, and the emergence of public art to assert the right to the city. I explore how artistic– activist interventions engage an understanding of social justice and the right to the city in provocative visual and performance art. I demonstrate how such interventions reflect Lefebvre’s conceptualisation of the city as a space to be inhabited in an active process, which critically includes its re-imagination. The paper focuses on creative interventions in Cape Town that confronted the city’s genteel public space with the second and third anniversary of the shooting of 34 striking miners at Marikana on August 16 2012. I argue that bringing the commemoration of the massacre into the public urban space – where post-apartheid Cape Town exhibits its claim to cosmopolitanism – challenges the politics of space in South Africa. I asked, how these cultural initiatives articulate claims through reimagining the city how they engage with the intertwined politics of culture and class followed by both the city and the nation–state, and how the artistic practices contest urban citizenship in contemporary South Africa

The post-occipital spinal venous sinus of the Nile crocodile (Crocodylus niloticus) : its anatomy and use for blood sample collection and intravenous infusions

The post-occipital sinus of the spinal vein is often used for the collection of blood samples from crocodilians. Although this sampling method has been reported for several crocodilian species, the technique and associated anatomy has not been described in detail in any crocodilian, including the Nile crocodile (Crocodylus niloticus). The anatomy of the cranial neck region was investigated macroscopically, microscopically, radiographically and by means of computed tomography. Latex was injected into the spinal vein and spinal venous sinus of crocodiles to visualise the regional vasculature. The spinal vein ran within the vertebral canal, dorsal to and closely associated with the spinal cord and changed into a venous sinus cranially in the post-occipital region. For blood collection, the spinal venous sinus was accessed through the interarcuate space between the atlas and axis (C1 and C2) by inserting a needle angled just off the perpendicular in the midline through the craniodorsal cervical skin, just cranial to the cranial borders of the first cervical osteoderms. The most convenient method of blood collection was with a syringe and hypodermic needle. In addition, the suitability of the spinal venous sinus for intravenous injections and infusions in live crocodiles was evaluated. The internal diameter of the commercial human epidural catheters used during these investigations was relatively small, resulting in very slow infusion rates. Care should be taken not to puncture the spinal cord or to lacerate the blood vessel wall using this route for blood collection or intravenous infusions.The Norwegian Council for Higher Education’s Programme for Development, Research and Education (NUFU 08/02) and the Royal Netherlands Embassy in South Africa (Prof. Nico Visser).http://www.jsava.co.zaam2014ab201

Transgenic Overexpression of the Type I Isoform of Neuregulin 1 Affects Working Memory and Hippocampal Oscillations but not Long-term Potentiation

Neuregulin 1 (NRG1) is a growth factor involved in neurodevelopment and plasticity. It is a schizophrenia candidate gene, and hippocampal expression of the NRG1 type I isoform is increased in the disorder. We have studied transgenic mice overexpressing NRG1 type I (NRG1tg-type I) and their wild-type littermates and measured hippocampal electrophysiological and behavioral phenotypes. Young NRG1tg-type I mice showed normal memory performance, but in older NRG1tg-type I mice, hippocampus-dependent spatial working memory was selectively impaired. Hippocampal slice preparations from NRG1tg-type I mice exhibited a reduced frequency of carbachol-induced gamma oscillations and an increased tendency to epileptiform activity. Long-term potentiation in NRG1tg-type I mice was normal. The results provide evidence that NRG1 type I impacts on hippocampal function and circuitry. The effects are likely mediated via inhibitory interneurons and may be relevant to the involvement of NRG1 in schizophrenia. However, the findings, in concert with those from other genetic and pharmacological manipulations of NRG1, emphasize the complex and pleiotropic nature of the gene, even with regard to a single isoform