Dynamics of the spontaneous breakdown of superhydrophobicity

Drops deposited on rough and hydrophobic surfaces can stay suspended with gas pockets underneath the liquid, then showing very low hydrodynamic resistance. When this superhydrophobic state breaks down, the subsequent wetting process can show different dynamical properties. A suitable choice of the geometry can make the wetting front propagate in a stepwise manner leading to {\it square-shaped} wetted area: the front propagation is slow and the patterned surface fills by rows through a {\it zipping} mechanism. The multiple time scale scenario of this wetting process is experimentally characterized and compared to numerical simulations.Comment: 7 pages, 5 figure

The covering factor of high redshift damped Lyman-α\alpha systems

We have used the Very Long Baseline Array to image 18 quasars with foreground damped Lyman-$\alpha$ systems (DLAs) at 327, 610 or 1420 MHz, to measure the covering factor $f$ of each DLA at or near its redshifted HI 21cm line frequency. Including six systems from the literature, we find that none of 24 DLAs at $0.09 < z < 3.45$ has an exceptionally low covering factor, with $f \sim 0.45 - 1$ for the 14 DLAs at $z > 1.5$, $f \sim 0.41 - 1$ for the 10 systems at $z < 1$, and consistent covering factor distributions in the two sub-samples. The observed paucity of detections of HI 21cm absorption in high-$z$ DLAs thus cannot be explained by low covering factors and is instead likely to arise due to a larger fraction of warm HI in these absorbers.Comment: 6 pages, 20 figures; MNRAS (Letters), in pres

General symptom reporting in female fibromyalgia patients and referents: a population-based case-referent study

<p>Abstract</p> <p>Background</p> <p>Fibromyalgia is characterized by widespread musculoskeletal pain and palpation tenderness. In addition to these classic symptoms, fibromyalgia patients tend to report a number of other complaints. What these other complaints are and how often they are reported as compared with related referents from the general population is not very well known. We therefore hypothesized that subjects with fibromyalgia report more of a wide range of symptoms as compared with referents of the same sex and age from the general population.</p> <p>Methods</p> <p>138 women with diagnosed fibromyalgia in primary health care and 401 referents from the general population matched to the cases by sex, age and residential area responded to a postal questionnaire where information on marital status, education, occupational status, income level, immigrant status, smoking habits physical activity, height and weight history and the prevalence of 42 defined symptoms was sought.</p> <p>Results</p> <p>The cases had lower educational and income levels, were more often unemployed, on sick leave or on disability pension and were more often first generation immigrants than the referents. They were also heavier, shorter and more often had a history of excessive food intake and excessive weight loss. When these differences were taken into account, cases reported not only significantly more presumed fibromyalgia symptoms but also significantly more of general symptoms than the referents. The distribution of symptoms was similar in subjects with fibromyalgia and referents, indicating a generally higher symptom reporting level among the former.</p> <p>Conclusion</p> <p>Subjects with fibromyalgia had a high prevalence of reported general symptoms than referents. Some of these differences may be a consequence of the disorder while others may reflect etiological processes.</p

Increased yield stability of field-grown winter barley (Hordeum vulgare L.) varietal mixtures through ecological processes

Crop variety mixtures have the potential to increase yield stability in highly variable and unpredictable environments, yet knowledge of the specific mechanisms underlying enhanced yield stability has been limited. Ecological processes in genetically diverse crops were investigated by conducting field trials with winter barley varieties (Hordeum vulgare), grown as monocultures or as three-way mixtures in fungicide treated and untreated plots at three sites. Mixtures achieved yields comparable to the best performing monocultures whilst enhancing yield stability despite being subject to multiple predicted and unpredicted abiotic and biotic stresses including brown rust (Puccinia hordei) and lodging. There was compensation through competitive release because the most competitive variety overyielded in mixtures thereby compensating for less competitive varieties. Facilitation was also identified as an important ecological process within mixtures by reducing lodging. This study indicates that crop varietal mixtures have the capacity to stabilise productivity even when environmental conditions and stresses are not predicted in advance. Varietal mixtures provide a means of increasing crop genetic diversity without the need for extensive breeding efforts. They may confer enhanced resilience to environmental stresses and thus be a desirable component of future cropping systems for sustainable arable farming

The g-2 of the Muon in Localized Gravity Models

The (g-2) of the muon is well known to be an important model building constraint on theories beyond the Standard Model. In this paper, we examine the contributions to $(g-2)_\mu$ arising in the Randall-Sundrum model of localized gravity for the case where the Standard Model gauge fields and fermions are both in the bulk. Using the current experimental world average measurement for $(g-2)_\mu$, we find that strong constraints can be placed on the mass of the lightest gauge Kaluza-Klein excitation for a narrow part of the allowed range of the assumed universal 5-dimensional fermion mass parameter, $\nu$. However, employing both perturbativity and fine-tuning constraints we find that we can further restrict the allowed range of the parameter $\nu$ to only one fourth of its previous size. The scenario with the SM in the RS bulk is thus tightly constrained, being viable for only a small region of the parameter space.Comment: 16 pages, 2 figs, LaTex, Additional discussion adde

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis:Results from the Norfolk Arthritis Register

Objectives: Anticarbamylated protein (anti-CarP) antibodies are a novel family of autoantibodies recently identified in patients with inflammatory arthritis. The aim of this study was to investigate their association with long-term outcomes of disability and disease activity over 20 years’ follow-up in a cohort of patients with inflammatory polyarthritis (IP).  Methods: Norfolk Arthritis Register recruited adults with recent-onset swelling of ≥2 joints for ≥4 weeks from 1990 to 2009. At baseline, Health Assessment Questionnaire (HAQ) and 28 joint disease activity scores (DAS28) were obtained, and C reactive protein, rheumatoid factor (RF), anticitrullinated protein antibodies (ACPA) and anti-CarP antibodies were measured. Further HAQ scores and DAS28 were obtained at regular intervals over 20 years. Generalised estimating equations were used to test the association between anti-CarP antibody status and longitudinal HAQ and DAS28 scores; adjusting for age, gender, smoking status, year of inclusion and ACPA status. Analyses were repeated in subgroups stratified by ACPA status. The relative association of RF, ACPA and anti-CarP antibodies with HAQ and DAS28 scores was investigated using a random effects model.  Results: 1995 patients were included; 1310 (66%) were female. Anti-CarP antibodies were significantly associated with more disability and higher disease activity, HAQ multivariate β-coefficient (95% CI) 0.12 (0.02 to 0.21), and these associations remained significant in the ACPA-negative subgroups. The associations of RF, ACPA and anti-CarP antibodies were found to be additive in the random effects model.  Conclusions: Anti-CarP antibodies are associated with increased disability and higher disease activity in patients with IP. Our results suggest that measurement of anti-CarP antibodies may be useful in identifying ACPA-negative patients with worse long-term outcomes. Further, anti-CarP antibody status provided additional information about RF and ACPA

Cold Gas Kinematics in an L* Spiral Galaxy at z=0.437: The Nature of Damped Lyman-alpha Absorbers

Westerbork Radio Synthesis Telescope observations of the redshifted 21cm line absorber against the z_em = 0.871 double lobed quasar 3C196 show that the intervening absorber is an L approximately equal L* spiral galaxy (3C196-G1) and that the absorbing layer of cold gas extends to radii of at least 30 h_50^-1 kpc. The new data solve several long standing puzzles about this system by (1) discovering a second 21cm absorption feature, corresponding to absorption against the NE lobe of the background radio source and (2) spatially ``resolving'' the two absorption features to isolate the absorption along the two lines of sight to the opposing radio lobes. These findings resolve the disagreement in redshift between the UV metal and 21cm lines, and as well as demonstrating that the neutral layer does absorb both lobes of the background radio source. Simple kinematic models with an inclined, rotating gas disk match the observed 21cm profile and are also compatible with both the redshift and velocity spread of the absorption measured in UV resonance lines along a third, independent line of sight to the quasar nucleus and with the lack of 21cm absorption in as earlier VLBI experiment that was sensitive to opacity against the hot spot in the northern lobe. The inferred rotation speed and luminosity for the galaxy are compatible with the z approximately 0 Tully-Fisher Relation. This system illustrates well how 21cm absorption against extended background radio sources is a powerful tool in determining the nature of the damped Lyman-alpha class of QSO absorption line system.Comment: 9 pages, accepted at A&

Economic evaluation of a clinical protocol for diagnosing emergency patients with suspected pulmonary embolism

BACKGROUND: The objective of this paper is to estimate the amount of cost-savings to the Australian health care system from implementing an evidence-based clinical protocol for diagnosing emergency patients with suspected pulmonary embolism (PE) at the Emergency department of a Victorian public hospital with 50,000 presentations in 2001–2002. METHODS: A cost-minimisation study used the data collected in a controlled clinical trial of a clinical protocol for diagnosing patients with suspected PE. Thenumber and type of diagnostic tests in a historic cohort of 185 randomly selected patients, who presented to the emergency department with suspectedPE during an eight month period prior to the clinical trial (January 2002 -August 2002) were compared with the number and type of diagnostic tests in745 patients, who presented to the emergency department with suspected PE from November 2002 to August 2003. Current Medicare fees per test were usedas unit costs to calculate the mean aggregated cost of diagnostic investigation per patient in both study groups. A t-test was used to estimate the statistical significance of the difference in the cost of resources used for diagnosing PE in the control and in the intervention group. RESULTS: The trial demonstrated that diagnosing PE using an evidence-based clinical protocol was as effective as the existing clinical practice. The clinical protocol offers the advantage of reducing the use of diagnostic imaging, resulting in an average cost savings of at least $59.30 per patient. CONCLUSION: Extrapolating the observed cost-savings of$59.30 per patient to the wholeof Australia could potentially result in annual savings between $3.1 million to$3.7 million