304 research outputs found
Considering even-order terms in stochastic nonlinear system modeling with respect to broadband data communication
As a tradeoff between efficiency and costs modern communication systems contain a variety of components that can at least be considered weakly nonlinear. A critical element in evaluating the degree of nonlinearity of any underlying nonlinear system is the amount of undesired signal strength or signal power this system is introducing outside the transmission bandwidth. This phenomenon called spectral regrowth or spectral broadening is subject to stringent restrictions mainly imposed by the given specifications of the particular communication standard. Consequently, achieving the highest possible efficiency without exceeding the linearity requirements is one of the main tasks in system design. Starting from this challenging engineering problem there grows a certain need for specialized tools that are capable of predicting linearity and efficiency of the underlying design. Besides a multitude of methods aiming at the prediction of spectral regrowth a statistical approach in modeling and analyzing nonlinear systems offers the advantage of short processing times due to closed form mathematical expressions in terms of input and output power spectra and is therefore further examined throughout this article
Spanish Mediterranean diet and other dietary patterns and breast cancer risk: case–control EpiGEICAM study
Background:Although there are solid findings regarding the detrimental effect of alcohol consumption, the existing evidence on the effect of other dietary factors on breast cancer (BC) risk is inconclusive. This study aimed to evaluate the association between dietary patterns and risk of BC in Spanish women, stratifying by menopausal status and tumour subtype, and to compare the results with those of Alternate Healthy Index (AHEI) and Alternate Mediterranean Diet Score (aMED).Methods:We recruited 1017 incident BC cases and 1017 matched healthy controls of similar age (±5 years) without a history of BC. The association between ‘a priori' and ‘a posteriori' developed dietary patterns and BC in general and according to menopausal status and intrinsic tumour subtypes (ER+/PR+ and HER2− HER2+ and ER−/PR− and HER2−) was evaluated using logistic and multinomial regression models.Results:Adherence to the Western dietary pattern was related to higher risk of BC (OR for the top vs the bottom quartile 1.46 (95% CI 1.06–2.01)), especially in premenopausal women (OR=1.75; 95% CI 1.14–2.67). In contrast, the Mediterranean pattern was related to a lower risk (OR for the top quartile vs the bottom quartile 0.56 (95% CI 0.40–0.79)). Although the deleterious effect of the Western pattern was similarly observed in all tumour subtypes, the protective effect of our Mediterranean pattern was stronger for triple-negative tumours (OR=0.32; 95% CI 0.15–0.66 and Pheterogeneity=0.04). No association was found between adherence to the Prudent pattern and BC risk. The associations between ‘a priori' indices and BC risk were less marked (OR for the top vs the bottom quartile of AHEI=0.69; 95% CI 0.51–0.94 and aMED=0.74; 95% CI 0.46–1.18)).Conclusions:Our results confirm the harmful effect of a Western diet on BC risk, and add new evidence on the benefits of a diet rich in fruits, vegetables, legumes, oily fish and vegetable oils for preventing all BC subtypes, and particularly triple-negative tumours
Experimental analysis of the TRC benchmark system
The Tribomechadynamics Research Challenge (TRC) was a blind prediction of the
vibration behavior of a thin plate clamped on two sides using bolted joints.
The first bending mode's natural frequency and damping ratio were requested as
function of the amplitude, starting from the linear regime until high levels,
where both frictional contact and nonlinear bending-stretching coupling become
relevant. The predictions were confronted with experimental results in a
companion paper; the present article addresses the experimental analysis of
this benchmark system. Amplitude-dependent modal data was obtained from phase
resonance and response controlled tests. An original variant of response
controlled testing is proposed: Instead of a fixed frequency interval, a fixed
phase interval is analyzed. This way, the high excitation levels required
outside resonance, which could activate unwanted exciter nonlinearity, are
avoided. Consistency of testing methods is carefully analyzed. Overall, these
measures have permitted to gain high confidence in the acquired modal data. The
different sources of the remaining uncertainty were further analyzed. A low
reassembly-variability but a moderate time-variability were identified, where
the latter is attributed to some thermal sensitivity of the system. Two
nominally identical plates were analyzed, which both have an appreciable
initial curvature, and a significant effect on the vibration behavior was found
depending on whether the plate is aligned/misaligned with the support
structure. Further, a 1:2 nonlinear modal interaction with the first torsion
mode was observed, which only occurs in the aligned configurations
Considering even-order terms in stochastic nonlinear system modeling with respect to broadband data communication
[No abstract
Eating disinhibition and vagal tone moderate the postprandial response to glycemic load: a randomised controlled trial
Comparative effects of different dietary approaches on blood pressure in hypertensive and pre-hypertensive patients: A systematic review and network meta-analysis
Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood
pressure but their comparative effects have not been established. Objective: Therefore we performed a
systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects
through network meta-analysis including hypertensive and pre-hypertensive patients. Design: PubMed,
Cochrane CENTRAL, and Google Scholar were searched until June 2017. The inclusion criteria were defined as
follows: i) Randomized trial with a dietary approach; ii) hypertensive and pre-hypertensive adult patients; and iii)
minimum intervention period of 12 weeks. In order to determine the pooled effect of each intervention relative
to each of the other intervention for both diastolic and systolic blood pressure (SBP and DBP), random effects
network meta-analysis was performed. Results: A total of 67 trials comparing 13 dietary approaches (DASH, lowfat, moderate-carbohydrate, high-protein, low-carbohydrate, Mediterranean, Palaeolithic, vegetarian, low-GI/GL,
low-sodium, Nordic, Tibetan, and control) enrolling 17,230 participants were included. In the network metaanalysis, the DASH, Mediterranean, low-carbohydrate, Palaeolithic, high-protein, low-glycaemic index, lowsodium, and low-fat dietary approaches were significantly more effective in reducing SBP (¡8.73 to
¡2.32 mmHg) and DBP (¡4.85 to ¡1.27 mmHg) compared to a control diet. According to the SUCRAs, the DASH
diet was ranked the most effective dietary approach in reducing SBP (90%) and DBP (91%), followed by the
Palaeolithic, and the low-carbohydrate diet (ranked 3rd for SBP) or the Mediterranean diet (ranked 3rd for DBP).
For most comparisons, the credibility of evidence was rated very low to moderate, with the exception for the
DASH vs. the low-fat dietary approach for which the quality of evidence was rated high. Conclusion: The present network meta-analysis suggests that the DASH dietary approach might be the most effective dietary measure toreduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
Corrigendum: Reviewing the links and feedbacks between climate change and air pollution in Europe
Protein intake and risk of urolithiasis and kidney diseases: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society
Land–atmosphere interactions in sub-polar and alpine climates in the CORDEX flagship pilot study Land Use and Climate Across Scales (LUCAS) models – Part 1: Evaluation of the snow-albedo effect
Seasonal snow cover plays a major role in the climate system of the Northern Hemisphere via its effect on land surface albedo and fluxes. In climate models the parameterization of interactions between snow and atmosphere remains a source of uncertainty and biases in the representation of local and global climate. Here, we evaluate the ability of an ensemble of regional climate models (RCMs) coupled with different land surface models to simulate snow–atmosphere interactions over Europe in winter and spring. We use a previously defined index, the snow-albedo sensitivity index (SASI), to quantify the radiative forcing associated with snow cover anomalies. By comparing RCM-derived SASI values with SASI calculated from reanalyses and satellite retrievals, we show that an accurate simulation of snow cover is essential for correctly reproducing the observed forcing over middle and high latitudes in Europe. The choice of parameterizations, and primarily the choice of the land surface model, strongly influences the representation of SASI as it affects the ability of climate models to simulate snow cover accurately. The degree of agreement between the datasets differs between the accumulation and ablation periods, with the latter one presenting the greatest challenge for the RCMs. Given the dominant role of land surface processes in the simulation of snow cover during the ablation period, the results suggest that, during this time period, the choice of the land surface model is more critical for the representation of SASI than the atmospheric model
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