25 research outputs found

    Compressive sensing-based robust off-the-grid stretch processing

    Get PDF
    Classical stretch processing (SP) obtains high range resolution by compressing large bandwidth signals with narrowband receivers using lower rate analogue-to-digital converters. SP achieves the resolution of the large bandwidth signal by focusing into a limited range window, and by deramping in the analogue domain. SP offers moderate data rate for signal processing for high bandwidth waveforms. Furthermore, if the scene in the examined window is sparse, compressive sensing (CS)-based techniques have the potential to further decrease the required number of measurements. However, CS-based reconstructions are highly affected by model mismatches such as targets that are off-the-grid. This study proposes a sparsity-based iterative parameter perturbation technique for SP that is robust to targets off-the-grid in range or Doppler. The error between reconstructed and actual scenes is measured using Earth mover's distance metric. Performance analyses of the proposed technique are compared with classical CS and SP techniques in terms of data rate, resolution and signal-to-noise ratio. It is shown through simulations that the proposed technique offers robust and high-resolution reconstructions for the same data rate compared with both classical SP- and CS-based techniques. © 2017, The Institution of Engineering and Technology

    Mucin expression in gastric- and gastro-oesophageal signet-ring cell cancer: results from a comprehensive literature review and a large cohort study of Caucasian and Asian gastric cancer

    Get PDF
    Background: The literature on the prognostic relevance of signet-ring cell (SRC) histology in gastric cancer (GC) is controversial which is most likely related to inconsistent SRC classification based on haematoxylin–eosin staining. We hypothesised that mucin stains can consistently identify SRC-GC and predict GC patient outcome. Methods: We performed a comprehensive literature review on mucin stains in SRC-GC and characterised the mucin expression in 851 Caucasian GC and 410 Asian GC using Alcian Blue (AB)-Periodic Acid-Schiff (PAS), MUC2 (intestinal-type mucin), and MUC5AC (gastric-type mucin). The relationship between mucin expression and histological phenotype [poorly cohesive (PC) including proportion of SRCs, non-poorly cohesive (non-PC), or mucinous (MC)], clinicopathological variables, and patient outcome was analysed. Results: Depending on mucin expression and cut-offs, the positivity rates of SRC-GC reported in the literature varied from 6 to 100%. Patients with MUC2 positive SRC-GC or SRC-GC with (gastro)intestinal phenotype had poorest outcome. In our cohort study, PC with ≥ 10% SRCs expressed more frequently MUC2, MUC5AC, and ABPAS (p < 0.001, p = 0.004 and p < 0.001, respectively). Caucasians with AB positive GC or combined ABPAS-MUC2 positive and MUC5AC negative had poorest outcome (all p = 0.002). This association was not seen in Asian patients. Conclusions: This is the first study to suggest that mucin stains do not help to differentiate between SRC-GC and non-SRC-GC. However, mucin stains appear to be able to identify GC patients with different outcome. To our surprise, the relationship between outcome and mucin expression seems to differ between Caucasian and Asian GC patients which warrants further investigations

    Unusual cause of cardiac compression in a trauma patient: Cystic thymoma

    No full text
    [No abstract available

    The current status of ethnopharmacobotanical knowledge in Camlidere (Ankara, Turkey)

    No full text
    The main objective of this study is to identify and record the folk medicines used in Camlidere (Ankara) as well as to contribute to the preservation of this precious lore. For this purpose field trips were organized to Camlidere. A total of 79 taxa belonging to 66 genera and 33 families were recorded for the treatment of various disorders. The most represented families were Asteraceae, Lamiaceae, and Rosaceae, respectively. Respiratory tract diseases were the principal reasons for using folk medicines. Eight new folk medicines were included in the Turkish ethnobotanical repository with this study. Different ethnobotanical usages such as fuel and food were also noted. Our data obtained from the research area showed some uses of plants that were newly introduced to the folk medicinal literature of Turkey. Moreover, ``Use value{''}, ``Informant consensus factor{''}, and ``Cultural importance index{''} were also calculated to evaluate the data statistically

    Investigations on the anti-ulcerogenic activity of Sideritis caesarea H. Duman, Aytac & Baser

    No full text
    WOS: 000536887800018PubMed: 32360801Ethnopharmacological relevance: Aerial parts of Sideritis caesarea H. Duman, Aytac & Baser are used for complaints such as stomach-aches, and intestinal spasms as traditional medicine in Kayseri, Turkey. Aim of study: To investigate the anti-ulcerogenic activity by using bioassay guided fractionation technique (BAGF) and to identify the compound(s) that are responsible for anti-ulcerogenic activity through ethanol-induced anti-ulcerogenic activity model in vivo. Materials and methods: Liquid-liquid partition and then different chromatographic techniques were utilized for the BAGF of the ethanol (80%) extract of the aerial parts of Sideritis caesarea. Ethanol-induced gastric ulcer method on rats was employed for the determination of the anti-ulcerogenic activity, and the ulcer index was also calculated for anti-ulcerogenic activity detection. Results: the ethanol (80%) extract of S. caesarea showed statistically potent anti-ulcerogenic activity (95.9% ulcer inhibition, p 2)]- 6 ''-O-acetyl-beta-D-glucopyranoside and isoscutellarein-7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-6 ''-O-acetyl-beta-D-glucopyranoside} were isolated from this fraction together with a sesquiterpene glycoside [(2E,6E)-2,6,10-trimethyl-2,6,11-dodecatriene-1,10-diol-1-O-beta-D-glucopyranoside] and two additional flavonoids {4'-O-methylhypolaetin-7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside and isoscutellarein- 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside}. Conclusions: Traditional use of S. caesarea in the treatment of stomach-aches was supported by this study and four flavonoids were isolated by using BAGF method and two of them were determined to have significant antiulcerogenic activity. Additionally, (2E,6E)-2,6,10-trimethyl-2,6,11-dodecatriene-1,10-diol-1-O-beta-D-glucopyranoside was obtained from a Sideritis genus for the first time.Scientific and Technological Research Council of Turkey-TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TBAG-112S581]This study was financially supported by "The Scientific and Technological Research Council of Turkey-TUBITAK" (project number: TBAG-112S581)

    The Prevalence and Risk Factors of Human Papillomavirus in Female Sex Workers

    No full text
    Objective: Human papillomavirus virus (HPV) is the major causative factor for cervical cancer, and sex workers are at high risk for HPV infection. In this study, we aimed to estimate the prevalence and risk factors of HPV infection among female sex workers (FSWs)

    Surgery for vascular tumor invasion

    No full text
    Aim. The aim of this paper was to evaluate our clinical experience and surgical results with oncologic procedures associated with major vascular resection and reconstruction on elective or emergent basis. Methods. A retrospective study was performed on patients who underwent major vascular resection for malignancy in our hospital between January 2000 and January 2011. Data collection was organized for patient demographics, intraoperative findings, and postoperative outcome. Results. Thirty-six patients were treated with 36 reconstructive procedures; 18 (50%) of them were major-vessel reconstruction, 11 (30.6%) of them were bypass procedures, and 7 (19.4%) of them were primary repair. Concomitant vascular interventions were performed electively as part of a planned oncologic procedure in 22 (61.1%) patients or emergently in 14 (38.8%) patients due to a vascular complication that occurred during tumor resection. Postoperative morbidity rate related to vascular intervention was 16.6% and mortality was observed in 2.8% of the patients due to pulmonary embolism. Conclusion. The results reported herein support that the need for resection and reconstruction of a major vascular structure should not prohibit the resection of any given tumor. The study demonstrates that most major vascular reconstructions have a high degree of success, and do not result major complications
    corecore