The Stanford how things work project

We provide an overview of the Stanford How Things Work (HTW) project, an ongoing integrated collection of research activities in the Knowledge Systems Laboratory at Stanford University. The project is developing technology for representing knowledge about engineered devices in a form that enables the knowledge to be used in multiple systems for multiple reasoning tasks and reasoning methods that enable the represented knowledge to be effectively applied to the performance of the core engineering task of simulating and analyzing device behavior. The central new capabilities currently being developed in the project are automated assistance with model formulation and with verification that a design for an electro-mechanical device satisfies its functional specification

VR in Nursing Facilities - A randomized controlled multicenter pilot study analyzing the changes in the state of mind of seniors in nursing facilities through the viewing of 360° videos

Context: VR as an application to enhance well-being is sparsely researched in the elderly population. The aim of the pilot study was to analyze the effect of 360° videos of different categories on the state of mind of seniors in nursing facilities. Furthermore, for the implementation in everyday life, the usability of the system and the experience for seniors should be evaluated. Methods: The VR experience was used as a supplement to existing care services in three facilities on eight subjects. Mood state was assessed using the Questionnaire for the Assessment of Happiness before and after the intervention. Demographic data and technology acceptance were collected beforehand. After the intervention, subjects were interviewed about confounding factors and side effects, and nursing home staff were interviewed about the usability of the system and the organizational concept of implementation. Results: There was a positive effect on state of mind. Gender and spatial mobility turned out to be influencing factors. Categories containing people, animals and action achieved the highest increases in the state of mind. Interest in using technical devices correlated negatively with the change in mood state. None of the subjects found the VR goggles distracting or reported motion sickness. Very good usability was indicated by the employees. Conclusion: A very high willingness to use this technology was found among nursing staff and residents. The tendencies of the positive effect of 360° videos on the state of mind, as well as differentiation based on the mentioned characteristics gender and spatial mobility, should be verified by a larger sample to empirically validate the use of this technology to increase the quality of life

Ontology Mediated Information Extraction with MASTRO SYSTEM-T

In several data-centric application domains, the need arises to extract valuable information from unstructured text documents. The recent paradigm of Ontology Mediated Information Extraction (OMIE) faces this problem by taking into account the knowledge expressed by a domain ontology, and reasoning over it to improve the quality of extracted data. MASTRO SYSTEM-T is a novel tool for OMIE, developed by Sapienza University and IBM Almaden Research. In this work, we demonstrate its usage for information extraction over real-world financial text documents from the U.S. EDGAR system

Net community production in the North Atlantic Ocean derived from Volunteer Observing Ship data

The magnitude of marine plankton net community production (NCP) is indicative of both the biologically driven exchange of carbon dioxide between the atmosphere and the surface ocean and the export of organic carbon from the surface ocean to the ocean interior. In this study the seasonal variability in the NCP of five biogeochemical regions in the North Atlantic was determined from measurements of surface water dissolved oxygen and dissolved inorganic carbon (DIC) sampled from a Volunteer Observing Ship (VOS). The magnitude of NCP derived from dissolved oxygen measurements (NCPinline image) was consistent with previous geochemical estimates of NCP in the North Atlantic, with an average annual NCPinline image of 9.5 ± 6.5 mmol O2 m−2 d−1. Annual NCPinline image did not vary significantly over 35° of latitude and was not significantly different from NCP derived from DIC measurements (NCPDIC). The relatively simple method described here is applicable to any VOS route on which surface water dissolved oxygen concentrations can be accurately measured, thus providing estimates of NCP at higher spatial and temporal resolution than currently achieved

Thiol-norbornene gelatin hydrogels : influence of thiolated crosslinker on network properties and high definition 3D printing

Photocrosslinkable gelatin hydrogels are excellent bioinks or biomaterial ink components to serve biofabrication applications. Especially the widely investigated gelatin-methacroyl (gel-MA) hydrogels hold an impressive track record. However, over the past decade, increasing attention is being paid to thiol-ene photo-click chemistry to obtain hydrogel networks benefitting from a faster reactivity (i.e. seconds vs minutes) along with superior biocompatibility and processability. In order to exploit this photo-click chemistry, often an ene-functionality (e.g. norbornene) is introduced onto gelatin followed by crosslinking in the presence of a multifunctional thiol (e.g. dithiothreitol). To date, very limited research has been performed on the influence of the applied thiolated crosslinker on the final hydrogel properties. Therefore, the present work assesses the influence of different thiolated crosslinkers on the crosslinking kinetics, mechanical properties and biological performance of the hydrogels upon encapsulation of primary adipose tissue-derived stem cells which indicated a cell viability exceeding 70%. Furthermore, the different formulations were processed using two-photon polymerization which indicated, in addition to differences in processing window and swelling ratio, a previously unreported phenomenon. At high intensities (i.e. 150 mW), the laser results in cleavage of the gelatin backbone even in the absence of distinct photo-cleavable functionalities. This can have potential to introduce channels or softer regions in gels to result in zones characterized by different degradation speeds or the formation of blood vessels. Consequently, the present study can be used to provide guidance towards tailoring the thiol-ene system towards the desired applications

Thank You to Our 2020 Peer Reviewers

Thank you to the reviewers of AGU Advances. In 2020, we all faced the enormous and unexpected challenges of the Covid‐19 pandemic, with its host of new and competing demands on our time. Thus, we are especially grateful to the 154 people who provided reviews for AGU Advances and helped our fledgling journal complete its first year. Peer‐review is essential to the process of doing and publishing science, and our reviewers have helped define our new journal by indicating papers expected to have broad impact that advance a discipline, have broad impact across disciplines, or have policy relevance. All papers submitted to AGU Advances first go through an editorial consultation. We are committed to respecting reviewers’ time and only send papers for review that the consulting editors agree meet our criteria. Sometimes this means we send papers back to the authors with suggestions how to improve the fit to our journal. Another way we try to streamline the review process is by giving the authors the option to transfer reviews if after review we decide the paper is better suited to another AGU journal. As a relatively new journal, we still have few enough reviewers that we do not want to identify them by name. Nonetheless, you know who you are. Please accept our sincere thanks for generously sharing your expertise and working to improve AGU Advances

Confronting Racism to Advance Our Science

As individuals serving on the AGU Advances editorial board, we condemn racism, affirm that Black Lives Matter, and recognize that inequality is built into the systems that have allowed us to prosper. We aim to persistently foster discussion about racism, inequity, and the need to make our community more diverse and inclusive. This will help AGU Advances do a better job in publishing important science that inclusively reflects the ideas and contributions of all in our community