2,354 research outputs found

    Volume and surface propellant heating in an electrothermal radio-frequency plasma micro-thruster

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    The temporal evolution of neutral gas temperature over the first 5 min of operation for an electrothermal radio-frequency micro-thruster with nitrogen (N2) propellant was measured using rovibrational band matching of the second positive N2 system. Three distinct periods of gas heating were identified with time constants of τ 1 = 8 × 10⁻⁵ s, τ 2 = 8 s, and τ 3 = 100 s. The fast heating (τ 1) is attributed to volumetric heating processes within the discharge driven by ion-neutral collisions. The slow heating (τ 3) is from ion neutralization and vibrational de-excitation on the walls creating wall heating. The intermediate heating mechanism (τ 2) is yet to be fully identified although some theories are suggested.This research was partially funded by the Australian Space Research Program (APT project) and the Australian Research Council Discovery Project (No. DP140100571)

    Isolation of 39 polymorphic microsatellite loci and the development of a fluorescently labelled marker set for the Eurasian badger

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    We have isolated 78 microsatellite loci from the Eurasian badger (Meles meles). Of the 52 loci characterized, 39 were found to be polymorphic. A fluorescently labelled primer set was developed to enable individual-specific 17-locus genotypes to be obtained efficiently

    Direct measurement of neutral gas heating in a radio-frequency electrothermal plasma micro-thruster

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    Direct measurements and modelling of neutral gas heating in a radio-frequency (13.56 MHz) electrothermal collisional plasma micro-thruster have been performed using rovibrational band matching of the second positive system of molecular nitrogen (N2) for operating pressures of 4.5 Torr down to 0.5 Torr. The temperature measured with decreasing pressure for 10 W power input ranged from 395 K to 530 K in pure N2 and from 834 K to 1090 K in argon with 1% N2. A simple analytical model was developed which describes the difference in temperatures between the argon and nitrogen discharges.Aspects of this research made use of software developed by the Inversion Laboratory (ilab). Ilab is part of the Auscope AGOS project—an initiative of the Australian Government funded through the Education Investment Fund

    Microscopic changes in the spinal extensor musculature in people with chronic spinal pain: a systematic review.

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    Chronic spinal pain is one the most common musculoskeletal disorders. Previous studies have observed microscopic structural changes in the spinal extensor muscles in people with chronic spinal pain. This systematic review synthesizes and analyses all the existing evidence of muscle microscopic changes in people with chronic spinal pain. To assess the microscopy of spinal extensor muscles including the fiber type composition, the area occupied by fiber types, fiber size/cross sectional area (CSA) and narrow diameter (ND) in people with and without chronic spinal pain. Further, to compare these outcome measures across different regions of the spine in people with chronic neck, thoracic and low back pain. Systematic review with meta-analysis METHODS: MEDLINE (Ovid Interface), Embase, PubMed, CINAHL Plus and Web of Science were searched from inception to October 2020. Key journals, conference proceedings, grey literature and hand searching of reference lists from eligible studies were also searched. Two independent reviewers were involved in the selection process. Only studies examining the muscle microscopy of the spinal extensor muscles (erector spinae (ES) and/or multifidus (MF)) between people with and without chronic spinal pain were selected. The risk of bias from the studies was assessed using modified Newcastle Ottawa Scale and the level of evidence was established using the GRADE approach. Data were synthesized based on homogeneity on the methodology and outcome measures of the studies for ES and MF muscles and only four studies were eligible for analysis. All the five studies included were related to chronic low back pain (CLBP). Meta-analysis (inverse variance method for random effect to calculate mean difference and 95% CI) was performed for the ES fiber type composition by numbers for both type I and type II fibers (I =43% and 0% respectively indicating homogeneity of studies) and showed no difference between the people with and without CLBP with an overall effect estimate Z= 1.49 (p=0.14) and Z=1.06 (p=0.29) respectively. Meta-analysis was performed for ES fiber CSA for both type I and type II fibers (I =0 for both) and showed no difference between people with and without CLBP with an overall effect estimate Z= 0.08 (p=0.43) and Z=0.75 (p=0.45) respectively. Analysis was not performed for ES area occupied by fiber types and ND due to heterogeneity of studies and lack of evidence respectively. Similarly, meta-analysis was not performed for MF fiber type composition by numbers due to heterogeneity of studies. MF analysis for area occupied by fiber type, fiber CSA and ND did not yield sufficient evidence. For the ES muscle, there was no difference in fiber type composition and fiber CSA between people with and without CLBP and no conclusions could be drawn for ND for the ES. For the MF, no conclusions could be drawn for any of the muscle microscopy outcome measures. Overall, the quality of evidence is very low and there is very low evidence that there are no differences in microscopic muscle features between people with and without CLBP. [Abstract copyright: Copyright © 2022. Published by Elsevier Inc.

    Physical activity interventions for treatment of social isolation, loneliness or low social support in older adults: A systematic review and meta-analysis of randomised controlled trials

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    Objectives This article reviews the effects of physical activity (PA) interventions on social isolation, loneliness or low social support in older adults. Design Systematic review and meta-analysis of randomised controlled trials (RCTs). Method MEDLINE, EMBASE, PsycINFO, the Cochrane CENTRAL, CINAHL, were screened up to February 2017. RCTs comparing PA versus non-PA interventions or control (sedentary) condition were included. Risk of bias was assessed using the 12 criteria Cochrane Review Book Group risk of bias. The outcome measures were: social isolation, loneliness, social support, social networks, and social functioning. Standardised mean differences (SMDs) with associated 95% confidence intervals (CIs) were calculated for continuous outcomes. Meta-analysis was performed using a random effects model. Results The search strategy identified 38 RCTs, with a total of 5288 participants, of which 26 had a low risk of bias and 12 had a high risk of bias. Meta-analysis was performed on 23 RCTs. A small significant positive effect favouring the experimental condition was found for social functioning (SMD = 0.30; 95% CI, 0.12 to 0.49; P = 0.001) with strongest effects obtained for PA interventions, diseased populations, group exercise setting, and delivery by a medical healthcare provider. No effect of PA was found for loneliness, social support, or social networks. Conclusion This review shows, for social functioning, the specific aspects of PA interventions can successfully influence social health. PA did not appear to be effective for loneliness, social support and social networks

    Physical Activity Intervention for Loneliness (PAIL) in community-dwelling older adults: protocol for a feasibility study

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    Background Low-quality social relationships in older adults are strongly associated with feelings of loneliness. Physical activity interventions could reduce loneliness and improve psychological well-being, among other health benefits. The aim of this study is to examine the feasibility of a Physical Activity Intervention for Loneliness (PAIL) in community-dwelling older adults at risk for loneliness. Methods/design This feasibility study is a two-arm randomised controlled trial (RCT) with a wait-list control group using a mixed-methods research design. The primary aim of the feasibility study is to estimate recruitment, retention and adherence rates; the appropriateness of the intervention design and its practicality; the acceptability of the intervention by participants; and the set of instruments and measures and primary outcome measures to inform a future large-scale randomised trial. After eligibility screening, randomisation will be conducted using computer-based random sequence generation. Baseline and post-intervention assessments for intervention and control groups will include height, weight, body mass index, resting blood pressure, physical activity using accelerometry, loneliness, social support, social networks, anxiety and depression, self-efficacy for exercise, satisfaction with social contacts, and expected outcomes and barriers for exercise using questionnaires. Focus groups will be conducted at the mid-point and post-intervention period using a phenomenological approach to analyse the participants’ experiences of taking part in PAIL. Discussion This trial will provide important information regarding the feasibility of PAIL in community-dwelling older adults at risk for loneliness using a mixed-methods approach combining quantitative and qualitative research methods

    New methods for unmixing sediment grain size data

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    Grain size distribution (GSD) data are widely used in Earth sciences and although large data sets are regularly generated, detailed numerical analyses are not routine. Unmixing GSDs into components can help understand sediment provenance and depositional regimes/processes. End-member analysis (EMA), which fits one set of end-members to a given data set, is a powerful way to unmix GSDs into geologically meaningful parts. EMA estimates end-members based on covariability within a data set and can be considered as a nonparametric approach. Available EMA algorithms, however, either produce suboptimal solutions or are time consuming. We introduce unmixing algorithms inspired by hyperspectral image analysis that can be applied to GSD data and which provide an improvement over current techniques. Nonparametric EMA is often unable to identify unimodal grain size subpopulations that correspond to single sediment sources. An alternative approach is single-specimen unmixing (SSU), which unmixes individual GSDs into unimodal parametric distributions (e.g., lognormal). We demonstrate that the inherent nonuniqueness of SSU solutions renders this approach unviable for estimating underlying mixing processes. To overcome this, we develop a new algorithm to perform parametric EMA, whereby an entire data set can be unmixed into unimodal parametric end-members (e.g., Weibull distributions). This makes it easier to identify individual grain size subpopulations in highly mixed data sets. To aid investigators in applying these methods, all of the new algorithms are available in AnalySize, which is GUI software for processing and unmixing grain size data

    Large Magellanic Cloud Planetary Nebula Morphology: Probing Stellar Populations and Evolution

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    Planetary Nebulae (PNe) in the Large Magellanic Cloud (LMC) offer the unique opportunity to study both the Population and evolution of low- and intermediate-mass stars, by means of the morphological type of the nebula. Using observations from our LMC PN morphological survey, and including images available in the HST Data Archive, and published chemical abundances, we find that asymmetry in PNe is strongly correlated with a younger stellar Population, as indicated by the abundance of elements that are unaltered by stellar evolution (Ne, Ar, S). While similar results have been obtained for Galactic PNe, this is the first demonstration of the relationship for extra-galactic PNe. We also examine the relation between morphology and abundance of the products of stellar evolution. We found that asymmetric PNe have higher nitrogen and lower carbon abundances than symmetric PNe. Our two main results are broadly consistent with the predictions of stellar evolution if the progenitors of asymmetric PNe have on average larger masses than the progenitors of symmetric PNe. The results bear on the question of formation mechanisms for asymmetric PNe, specifically, that the genesis of PNe structure should relate strongly to the Population type, and by inference the mass, of the progenitor star, and less strongly on whether the central star is a member of a close binary system.Comment: The Astrophysical Journal Letters, in press 4 figure
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