An fMRI investigation of the relationship between future imagination and cognitive flexibility

While future imagination is largely considered to be a cognitive process grounded in default mode network activity, studies have shown that future imagination recruits regions in both default mode and frontoparietal control networks. In addition, it has recently been shown that the ability to imagine the future is associated with cognitive flexibility, and that tasks requiring cognitive flexibility result in increased coupling of the default mode network with frontoparietal control and salience networks. In the current study, we investigated the neural correlates underlying the association between cognitive flexibility and future imagination in two ways. First, we experimentally varied the degree of cognitive flexibility required during future imagination by manipulating the disparateness of episodic details contributing to imagined events. To this end, participants generated episodic details (persons, locations, objects) within three social spheres; during fMRI scanning they were presented with sets of three episodic details all taken from the same social sphere (Congruent condition) or different social spheres (Incongruent condition) and required to imagine a future event involving the three details. We predicted that, relative to the Congruent condition, future simulation in the Incongruent condition would be associated with increased activity in regions of the default mode, frontoparietal and salience networks. Second, we hypothesized that individual differences in cognitive flexibility, as measured by performance on the Alternate Uses Task, would correspond to individual differences in the brain regions recruited during future imagination. A task partial least squares (PLS) analysis showed that the Incongruent condition resulted in an increase in activity in regions in salience networks (e.g. the insula) but, contrary to our prediction, reduced activity in many regions of the default mode network (including the hippocampus). A subsequent functional connectivity (within-subject seed PLS) analysis showed that the insula exhibited increased coupling with default mode regions during the Incongruent condition. Finally, a behavioral PLS analysis showed that individual differences in cognitive flexibility were associated with differences in activity in a number of regions from frontoparietal, salience and default-mode networks during both future imagination conditions, further highlighting that the cognitive flexibility underlying future imagination is grounded in the complex interaction of regions in these networks

The parent?infant dyad and the construction of the subjective self

Developmental psychology and psychopathology has in the past been more concerned with the quality of self-representation than with the development of the subjective agency which underpins our experience of feeling, thought and action, a key function of mentalisation. This review begins by contrasting a Cartesian view of pre-wired introspective subjectivity with a constructionist model based on the assumption of an innate contingency detector which orients the infant towards aspects of the social world that react congruently and in a specifically cued informative manner that expresses and facilitates the assimilation of cultural knowledge. Research on the neural mechanisms associated with mentalisation and social influences on its development are reviewed. It is suggested that the infant focuses on the attachment figure as a source of reliable information about the world. The construction of the sense of a subjective self is then an aspect of acquiring knowledge about the world through the caregiver's pedagogical communicative displays which in this context focuses on the child's thoughts and feelings. We argue that a number of possible mechanisms, including complementary activation of attachment and mentalisation, the disruptive effect of maltreatment on parent-child communication, the biobehavioural overlap of cues for learning and cues for attachment, may have a role in ensuring that the quality of relationship with the caregiver influences the development of the child's experience of thoughts and feelings

The intrinsic neural architecture of inhibitory control: The role of development and emotional experience

Inhibitory control is a key determinant of goal-directed behavior. Its susceptibility to reward implies that its variations may not only reflect cognitive ability, but also sensitivity to goal-relevant information. Since cognitive ability and motivational sensitivity vary as a function of age and mood, we hypothesized that their relevance for predicting individual differences in inhibition would similarly vary. Here, we tested this prediction with respect to the brain's intrinsic functional architecture. Specifically, we reasoned that age and affective functioning would both moderate the relationship between inhibition and resting state expression of the dynamic neural organization patterns linked to engaging in cognitive effort versus those involved in manipulating motivationally salient information. First, we used task fMRI data from the Human Connectome Project (N = 359 participants) to identify the brain organization patterns unique to effortful cognitive processing versus manipulation of motivationally relevant information. We then assessed the association between inhibitory control and relative expression of these two neural patterns in an independent resting state dataset from the Nathan Kline Institute-Rockland lifespan sample (N = 247). As hypothesized, the relation between inhibition and intrinsic functional brain architecture varied as a function of age and affective functioning. Among those with superior affective functioning, better inhibitory control in adolescence and early adulthood was associated with stronger resting state expression of the brain pattern that typified processing of motivationally salient information. The opposite effect emerged beyond the age of 49. Among individuals with poorer affective functioning, a significant link between inhibition and brain architecture emerged only before the age of 28. In this group, superior inhibition was associated with stronger resting state expression of the neural pattern that typified effortful cognitive processing. Our results thus imply that motivational relevance makes a unique contribution to superior cognitive functioning during earlier life stages. However, its relevance to higher-order mentation decreases with aging and increased prevalence of mood-related problems, which raises the possibility that patterns of neurobehavioral responsiveness to motivational salience may constitute sensitive markers of successful lifespan development

A Graphical PIN Authentication Mechanism for Smart Cards and Low-Cost Devices

Passwords and PINs are still the most deployed authentication mechanisms and their protection is a classical branch of research in computer security. Several password schemes, as well as more sophisticated tokens, algorithms, and protocols, have been proposed during the last years. Some proposals require dedicated devices, such as biometric sensors, whereas, others of them have high computational requirements. Graphical passwords are a promising research branch, but implementation of many proposed schemes often requires considerable resources (e.g., data storage, high quality displays) making difficult their usage on small devices, like old fashioned ATM terminals, smart cards and many low-price cellular phones. In this paper we present a graphical mechanism that handles authentication by means of a numerical PIN, that users have to type on the basis of a secret sequence of objects and a graphical challenge. The proposed scheme can be instantiated in a way to require low computation capabilities, making it also suitable for small devices with limited resources. We prove that our scheme is effective against "shoulder surfing" attacks. © 2008 Springer-Verlag Berlin Heidelberg