The FORTRAN static source code analyzer program (SAP) user's guide, revision 1

The FORTRAN Static Source Code Analyzer Program (SAP) User's Guide (Revision 1) is presented. SAP is a software tool designed to assist Software Engineering Laboratory (SEL) personnel in conducting studies of FORTRAN programs. SAP scans FORTRAN source code and produces reports that present statistics and measures of statements and structures that make up a module. This document is a revision of the previous SAP user's guide, Computer Sciences Corporation document CSC/TM-78/6045. SAP Revision 1 is the result of program modifications to provide several new reports, additional complexity analysis, and recognition of all statements described in the FORTRAN 77 standard. This document provides instructions for operating SAP and contains information useful in interpreting SAP output

Running Mad for Kentucky: Frontier Travel Accounts

The crossing of America’s first great divide—the Appalachian Mountains—has been a source of much fascination but has received little attention from modern historians. In the eighteenth century, the Wilderness Road and Ohio River routes into Kentucky presented daunting natural barriers and the threat of Indian attack. Running Mad for Kentucky brings this adventure to life. Primarily a collection of travel diaries, these day-to-day accounts illustrate the dangers thousands of Americans, adult and child, black and white, endured to establish roots in the wilderness. Ellen Eslinger’s vivid and extensive introductory essay draws on numerous diaries, letters, and oral histories of trans-Appalachian travelers to examine the historic consequences of the journey, a pivotal point in the saga of the continent\u27s indigenous people. The book demonstrates how the fabled soil of Kentucky captured the imagination of a young nation. Ellen Eslinger, professor of history at DePaul University, is the author of Citizens of Zion: The Social Origins of Camp Meeting Revivalism. An effective introduction to travel narratives of the Appalachian migration. Eslinger should be commended for bringing these sources together in an attractive, well annotated, and easily digested volume. -- Glenn Crothers, University of Louisville, Journal of the American Studies Association “Eslinger has previously produced solid scholarship on the Virginia backcountry and the Kentucky frontier, and her introduction to this volume is no different. . . . [She] has edited the travel accounts themselves well.”—Ohio Valley History Ellen Eslinger\u27s Running Mad for Kentucky: Frontier Travel Accounts is an excellent collection of thirteen first-person accounts by individuals who made the journey from the East into Kentucky between 1775 and 1796. -- Kentucky Ancestors Named a 2005 Choice Outstanding Academic Title.https://uknowledge.uky.edu/upk_united_states_history/1002/thumbnail.jp

Factors Affecting End of Treatment Symptom Severity for Children Receiving Trauma-Informed Evidence-Based Treatment

The purpose of this project is to examine how the factors of gender, placement status, type of treatment, the number of different types of trauma experienced, and a child’s age at the start of treatment may influence end of treatment symptom severity scores for children ages 2-12 years who received trauma-informed evidence-based treatment for trauma. Method: Caregivers and children receiving outpatient services (N=134) completed the Child Behavioral Checklist, Trauma Symptom Checklist for Young Children, and the Trauma Symptom Checklist for Children-Alternate Version at baseline and end of treatment. Hypotheses were tested with a series of ANCOVA analyses, Independent t-Tests, and a Paired Samples t-Test. Results: While statistically significant improvements were found between baseline and termination outcome scores regardless of treatment type, TF-CBT was found to more successfully reduce externalizing and total problem scores at termination compared to PCIT. Despite the relatively young age of this sample, significant differences in externalizing and total problem scores on the CBCL were found for older children at the end of treatment. No significant differences were found between pre-and post-test internalizing and externalizing scale scores for either TF-CBT or PCIT. Additionally, examination of caregiver and child daily functioning scale scores indicated improved ratings of daily functioning from baseline to the end of treatment. Implications: Behavior problems stemming from traumatic exposure may resolve differently from behaviors that result from environmental factors apart from trauma. Trauma recovery is dependent upon successful matching of client characteristics and need to treatment type. Practitioners are encouraged to be mindful of the specialized needs of older children who are seeking treatment. Research that focuses on clarifying the factors that differentiate symptom resolution can inform treatment selection decisions. Social work educators are encouraged to design curriculum that is trauma-informed with an emphasis on helping students learn how to think critically about a child’s needs and to integrate this knowledge into treatment decisions. The development of policies that incentivize agencies to provide evidence-based care can increase the availability of research-supported care for trauma exposed youth

Recommended approach to sofware development

A set of guideline for an organized, disciplined approach to software development, based on data collected and studied for 46 flight dynamics software development projects. Methods and practices for each phase of a software development life cycle that starts with requirements analysis and ends with acceptance testing are described; maintenance and operation is not addressed. For each defined life cycle phase, guidelines for the development process and its management, and the products produced and their reviews are presented

The Role of SLAM-Associated Protein in T Cell Signaling and Apoptosis.

X-linked Lymphoproliferative type 1 (XLP1) disease is a rare inherited syndrome characterized by generalized immunodeficiency, an extreme sensitivity to viral infections and a predisposition to the development of lymphoma. The disease is caused by loss-of-function mutations in the gene encoding the SLAM-associated protein (SAP). SAP is a SH2-domain-containing protein that interacts with the cytoplasmic tail of signaling receptors and protein tyrosine kinases to promote T cell activation following stimulation of the T cell receptor (TCR). T cell signaling regulates the balance between cell activation and death, and defects contribute to the lymphoproliferative nature of the disease. Previous studies have examined the various roles of SAP in modulating T cell responses, but these influences require further investigation, and are the focus of this study. To clarify the role of SAP in T cell signaling, we took a gene editing approach to disrupt the SAP gene and created a SAP-null T cell line. Through this approach we identified SAP-specific effects, which included cytokine production, transcription factor activity, and calcium mobilization. Interestingly, SAP-null cells exhibited a decrease in IL-2 expression, attributable to defective nuclear factor of activated T cells (NFAT) activation, and increased IFN-g production following TCR stimulation. Moreover, cells with SAP deficiencies have a heightened sensitivity to apoptotic stimuli. These results suggest that SAP defects drastically alter T cell activation and the cytokine environment, making T cells more sensitive to apoptotic stimuli, potentially impeding their ability to respond to immune challenges. Together, these results identify specific SAP-dependent defects in T cell signaling that could contribute to the characteristic phenotypes of patients with XLP1 disease.PhDCancer BiologyUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/113369/1/eslingem_1.pd

Avalon Submersible Support Structure

The Morro Bay Maritime Museum (MBMM) is a local non-profit organization that is currently looking for a new way to support the Deep Submergence Rescue Vehicle (DSRV), Avalon, that they have on display. The DSRV is currently sitting on a Short Haul Vehicle (SHV) trailer and the total weight (32 tons) is currently being supported by the SHV’s tires. This is a source of concern for the MBMM due to the weathering the tires have undergone. The MBMM is looking for a support structure that will aesthetically add to the display and take the weight off of the tires for safety. The Maritime Museum wants to professionally manufacture and install this structure by the end of June 2017. In order to meet this deadline, we will have a final design report completed by June 2, 2017. The report will include a description of our final design, the manufacturing process, and a summary of the performed testing and analysis. We also intend to include a detailed CAD model, the accompanying engineering drawings, and a full scale prototype of the support structure at that time