La diferencia como complemento de la igualdad en la protección de los derechos fundamentales. Elementos teóricos para su consideración

The present investigation reviews the political and philosophical discourse of Modernity, from a critic perspective, specially its influence on fundamental rights and their universal titularity. The authors propose the notion of difference as an epistemological complement for the modern comprehension on rights, from the material perspective that determines it exercise. This critic exploration aims to a reconstruction of fundamental rights theory, from certain materialism of difference and subalternity theory, which considers this condition in their exercise, especially guaranteeing equality among social groups whose identity configures from difference, like immigrants.El presente trabajo aborda críticamente la influencia del discurso político y filosófico en la comprensión de los derechos fundamentales, particularmente desde la crítica a las nociones de sujeto abstracto y titularidad universal. Este ejercicio propone la noción de diferencia como complemento epistémico para la comprensión de estos derechos, que permita situar a sus titulares en la materialidad que condiciona el ejercicio. Esta exploración tiene como horizonte una reconstrucción del discurso de los derechos desde una epistemología materialista de la diferencia y la subalternidad, que considere dicha condición en su ejercicio, especialmente cuando se trata de garantizar la igualdad de personas pertenecientes a grupos sociales cuya identidad se configura, como en el caso de las personas migrantes, desde la diferencia

Variability in presentation and management of gastric volvulus: report of 3 cases

Gastric volvulus is a pathology of acute or subacute presentation. Depending on the type, a gastric volvulus can present as an emergency if there is vascular compromise with necrosis and high risk of perforation and its surgical resolution is mandatory. Subacute gastric volvulus does not compromise the organ or organism urgently but is associated with high morbidity and should be resolved when the patient is in optimal conditions to offer definitive treatment. Depending on the torsion axis, it is classified as axial or mesenteroaxial organ, both merit reduction according to their presentation and the clinical context of the patient.

The effects of DNA methylation and histone deacetylase inhibitors upon the human papillomavirus early genes expression in cervical cancer. An in vitro and clinical study

BACKGROUND: The methylation status at the human papilloma virus (HPV) genome found in pre-invasive and invasive cervical lesions suggests that neoplastic transformation can be suppressed by gene hypermethylation, whereas hypomethylation accompanies or causes cancer progression; hence, epigenetic therapy aimed at reactivating cellular suppressor-gene expression has the potential to act as a tumor promoter by enhancing HPV oncoprotein expression in HPV-related malignancies. The objective of this study was to determine the influence of hydralazine and valproate on HPV oncogene expression in cervical cancer cell lines and the primary tumors of patients undergoing treatment with hydralazine and valproate. RESULTS: Overall, hydralazine and valproate either alone or combined exerted a growth inhibitory effect on cervical cancer cell lines. A cell line-specific up-regulating effect was observed on E6/E7 gene expression, which in general correlated with DNA hypomethylation and histone acetylation at the long control region (LCR). Nonetheless, E6/E7 expression was unchanged or decreased in the majority of patients with cervical cancer treated with hydralazine, valproate, or both. In some cervical cancer cell lines, these drugs led to increased transcription of p53, and increased its stabilization due to acetylation at lysines 273 and 282, which allowed a higher bax-protein transactivating effect. CONCLUSION: The results of this study demonstrate that hydralazine and valproate can be safely administered to HPV-related malignancies such as cervical cancer because they do not increase viral oncoprotein expression. Most importantly, the antitumor effect of hydralazine and valproate in cervical cancer may at least partially depend on an up-regulating effect on p53 gene and on the valproate-induced hyperacetylation of p53 protein, protecting it from degradation by E6

Circulation Weather types as a key factor on runoff initation and sediment detachment in mediterranean shrublands

In this research, the circulation weather types (CWTs) associated with individual surface pressure data at different atmospheric heights were used to correlate and quantify soil erosion events collecting soil loss (g m-2), runoff (l m-2) and sediment concentration (g L-1) using field plots and sediment collectors. RepresentativeMediterranean shrubland, located at Sierra de Enguera (Eastern Spain), was used as a case study where 213 rainfallepisodes and related soil loss events were recorded for the 2010-2014 period. Average annual precipitation of 544mm was registered, summarizing a total of 2,720.1 mm for the five years of the research period. A total of 34.4%of the registered precipitation events ranged from 10 to 29.9 mm, 23.5% from 30 to 49.9 mm, and 15.9% from 50to 99.9 mm. The dynamic low-pressure with fronts (DLp+f) CWT was found to generate the highest precipitationamount reaching 60.6% of the total precipitation (105 of the 213 events). Over a third (35%) of the precipitationevents occurred during Eastern CWT, which accounted for 48% of the total precipitation with average values of17.6 mm per event. From the total runoff, 65.6% was related to the combined Eastern and cold drops (CD) CWT.The DLp+f CWT was found to produce 48.9% of sediment mobilization, of which 73.5% of this amount wasgenerated by Eastern CWT. The highest sediment concentration event was found for the southern CWT underthermal low-pressure (TLp) reaching 51.65 g L-1, followed by A (anticyclones) with the Eastern CWT (42.23 g L-1).As a whole, the southern is the CWT generating the highest average sediment concentration (28.66 g L-1), followedby Easter CWT. Our findings suggest that CWTs contribute to foreseeing the periods with the highest soil lossesand may help to prevent them. We discuss the need to analyse the changes in soil erosion rates due to CWT tobetter characterize the soil erosion process and assess the soil erosion rates, improve the current soil erosion modelsand investigate how climate change is changing the role CWT plays in runoff initiation and sediment delivery

Secondary phytohaemagglutinin (PHA) swelling response is a good indicator of T-cell-mediated immunity in free-living birds

El phytohaemagglutinin (PHA) se prueba para medir la inmunidad adquirida y es uno de los métodos más utilizados; actualmente, está siendo debatido a raíz de los nuevos conocimientos sobre la compleja fisiología del proceso. Como respuesta secundaria reiterada a los mayores desafíos vinculados a los aumentos de los niveles de linfocitos T circulantes sería indicativo de una respuesta inmune mediada por células, se realizó por primera vez un experimento bajo condiciones naturales con repetidas PHA desafíos en libre-viviendo los pájaros adultos y polluelos para arrojar luz sobre este tema. Hemos encontrado significativamente más fuerte respuesta a PHA inyección secundaria independiente del sexo o la edad, mientras que el control de la condición corporal, la segunda respuesta es en promedio 90% más grande que el primero. Igualmente, los recuentos de linfocitos fueron significativamente superiores en el segundo reto de PHA, mientras que no se encontraron diferencias significativas entre las aves no tratadas. Las correlaciones positivas significativas entre la PHA respuesta y ambos recuentos de linfocitos y los niveles de proteínas plasmáticas (principalmente albúmina, globulina (precursor) fueron recuperados, mientras que no hubo diferencias significativas en los niveles de proteínas plasmáticas recuperados entre los retos. Nuestros resultados son consistentes con las aves cautivas, apoyando la validez del PHA de la hinchazón de la piel como prueba precisa de haber adquirido células T como la inmunidad en aves.The validity of using the phytohaemagglutinin (PHA) test to measure acquired immunity, one of the most widely used methods, is currently being debated due to new knowledge on the complex physiology of the process. As a greater secondary response to repeated challenges linked to increases of circulating lymphocyte levels would be indicative of a T-cell-mediated immune response, we performed for the first time an experiment under natural conditions with repeated PHA challenges in free-living adult birds and chicks to shed light on this topic. We found significantly stronger secondary response to PHA injection independent of sex or age, while controlling for body condition, the second response being on average 90% larger than the first. Likewise, lymphocyte counts were significantly higher in the second PHA challenge, whereas no significant differences were found among untreated birds. Significant positive correlations between the PHA response and both lymphocyte counts and plasma protein levels (mainly albumin, globulin (precursor) were recovered, whereas no significant differences were recovered in plasma protein levels between challenges. Our results are consistent with those from captive birds, supporting the validity of the PHA skin-swelling test as an accurate gauge of acquired T-cell-mediated immunity in birds.Trabajo patrocinado por: Fondo Mejicano para Conservación de la Naturaleza. Proyecto PIE 2012 A-P-C-IGSI-12-12 Gobierno de Extremadura. CONACYT (I010/176/2012) y becas PO10014 y RE12002 Gobierno de Extremadura. Dirección General de Vida Silvestre. SGPA/ DGVS/08559/11peerReviewe

ACELERACIÓN DE CORIOLIS, UN MÉTODO DE FÁCIL ENSEÑANZA-APRENDIZAJE (CORIOLIS ACCELERATION, AN EASY TEACHING-LEARNING METHOD)

ResumenDinámica es un curso esencial en cualquier carrera de ingeniería. En ese sentido la aceleración de Coriolis, a pesar de haber sido ampliamente estudiada en diversos libros de texto y artículos científicos, representa un tópico retador para la enseñanza. En consecuencia, los estudiantes experimentan problemas en comprender la conexión entre las expresiones matemáticas y el significado físico del fenómeno. Esto es debido al hecho de que usualmente la aceleración de Coriolis se explica con base en un sistema de referencia rotatorio y otro inercial, por ejemplo, en libros de texto típicos la aceleración de Coriolis se deduce y explica en solo dos páginas.  El método expuesto en este trabajo es más general y puede ser fácilmente extendido a los análisis cinemáticos de orden superior del cuerpo rígido debido a que éste está basado en simples derivadas temporales de vectores que relacionan cuerpos rígidos en movimiento general.Palabra(s) Clave: Aceleración, Cinemática, Coriolis, Enseñanza/Aprendizaje, Vector anclado, Vector libre. AbstractDynamics is an essential issue in any engineering program. In that concern Coriolis acceleration, eventhough that it has been widely addressed in many textbooks and technical papers, represents a challenging topic to teach. Consequently, undergraduate students undergo troubles to understand the connection between the mathematical expressions and the physical meaning of the phenomenon. This is due to the fact that usually the Coriolis acceleration is briefly explained based on rotating frames of reference and one noninertial frame, e.g., in typical textbooks the Coriolis acceleration is derived and explained in only two pages. The method exposed in the contribution is more general and can be easily extended to higher-order kinematic analyses of rigid body owing that it is based on simple time derivatives of vectors relating bodies in general motionKeywords: Acceleration, Bound vector, Coriolis, Free vector, Kinematics, Teaching/Learning

Codesign towards a conceptual proposal for a serious game in environmental education

Este artículo presenta la etapa de conceptualización de un juego serio en educación ambiental para el consumo responsable de alimentos. Las propuestas fueron realizadas por diecinueve jóvenes de la Universidad Veracruzana a lo largo de las actividades de conceptualización, diseño e implementación de un juego serio; y que previamente exploraron un juego serio como referente. Se incluyen aquí los resultados derivados del Brainstorming (técnica utilizada dentro del método de Pensamiento de diseño); y del proceso de Codiseño seguido por los equipos interdisciplinarios al crear sus propuestas conceptuales para un juego serio en educación ambiental, lo anterior en concordancia a la guía de un Documento de diseño para juegos. En esta fase de experimentación activa, los/las participantes identifican que estos métodos contribuyeron al desarrollo de su proceso creativo, a la claridad para conceptualizar, validar ideas grupales, construir con base en ellas nuevos conceptos y manifiestan interés por participar colaborativamente en proyectos de diseño de juegos serios para la educación ambiental.This paper presents the conceptualizing phase, for a serious game in environmental education on responsible food consumption. The proposals were developed by nineteen students of Universidad Veracruzana, along with the activities of conceptualizing, designing, and implementing a serious game, and they previously explored a serious game as a reference. The research includes the results achieved when applying Brainstorming (a technique used in the Design Thinking method), as well as the results from a Codesign process followed by the interdisciplinary teams when developing their conceptual proposals for a serious game in environmental education, all the above according to a Game Design Document guide. In this phase of active experimentation, the participants acknowledge that these methods support them in developing their creative process and clarity to conceptualize, they validate group ideas to build new concepts based on them and they express interest to participate collaboratively in the design projects of serious games in environmental education

Cinética de la fotodegradación del colorante azo azul reactivo 69

Se estudió la fotodegradación del colorante azo azul reactivo 69 (azul lanasol), mediante el empleo de semiconductores a base de Fe₂O₃, empleando como fuente de irradiación la luz solar y peróxido de hidrógeno como agente oxidante. Resultados de caracterización estructural textural muestran la formación de tres fases cristalinas, así como formas y tamaños de agregados y de poros irregulares, mientras que las propiedades ópticas muestran un ancho de banda y una energía de Urbach en la región visible. Los resultados de fotoactividad muestran una clara dependencia del pH, temperatura de calcinación, tipo de precursor y Eg. Los resultados experimentales pueden ser descritos mediante una ecuación diferencial ordinaria de orden dos, en donde se incluyen factores cinéticos, adsorción-desorción, transferencia de masa e intensidad de la luz, con un error de 6% aproximado.The photodegradation of the reactive blue azo dye 69 (lanasol blue) was studied through the use of Fe₂O₃-based semiconductors, using sunlight as irradiation source and hydrogen peroxide as an oxidizing agent. Structural and textural characterization results show the formation of three crystalline phases, as well as it was found that all samples show irregular shapes, pores and sizes of aggregates, while the optical properties show a band gap energy the visible region and width Urbach energy. The photoactivity results show a clear dependence on pH, calcination temperature, type of precursor and band gap energy. Experimental results can be described by means of a second order ordinary differential equation, which includes kinetic, adsorptiondesorption, mass transfer and light intensity factors, with an error of 6% approximately

Plan de marketing beach soccer UES masculino

Este trabajo presenta una propuesta de marketing, gestión de calidad y patrocinio para Beach Soccer UES Masculino, con el objetivo de expandirse hacia el público. En el área de marketing se investigó el posicionamiento que este tiene en el mercado, definiendo estrategias y tácticas de marketing acordes al público objetivo y así se elaboró un plan de acción. Elaborando un instrumento de investigación se buscó conocer la valoración de los clientes acerca de la calidad de servicio en el Club BS-UES, infraestructura, mantenimiento de instalaciones, publicidad y marketing, dando como resultado una herramienta donde se reflejaron los puntos fuertes y débiles en los servicios de Beach Soccer UES. El modelo EFQM se utilizó para evaluar diversos criterios ya establecidos, con el resultado de esto se ubicó a la empresa en uno de los niveles que el modelo especifica. Con el objetivo contribuir al desarrollo integral en la niñez o adolescencia siendo participes de dicha disciplina deportiva generar convenios con marcas reconocidas con un enfoque en el deporte, se elaboró un de Plan de Patrocinio donde se planteó un evento nacional de fútbol playa en el cual se buscarían beneficios que ayuden a la optimización de los recursos para el evento por parte el club BS-UES y maximizar el aporte de empresas patrocinadoras

Quantic Analysis of the Adherence of a Gram-Negative Bacteria in A HEPA Filter

It is known that Gram-negative bacteria (GNB) are the most frequent bacteria in hospital units. It is also known that GNBs generate a greater number of nosocomial infections in critical areas. In the present work, the adhesion of the bacterial cell wall (BCW) to the compounds of the material layers of a high efficiency filter (HEPA) was analyzed. The analysis was carried out by means of molecular simulation and quantum chemistry. The BCW and HEPA molecules were designed using Hyperchem software for simulation. The calculations of the quantum interactions of the molecules were carried out using the theory of the electron transfer coefficient (ETC). It obtained from 4 to 6 compounds that are more likely to interact even as a chemical reaction. The compounds of the glass fibers are the ones that work best for the adhesion and destruction of the BCW