821 research outputs found

    Mapaje físico y caracterización de genes humanos

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    Mimosa

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    Mimosa neix de la combinació de dues passions d’àmbits molt diferents que gràcies a aquest projecte poden confluir. Es tracta de la fusió del món de les plantes i tot allò que les envolta, amb el terreny editorial. La unió d’ambdues disciplines ha donat lloc al projecte que ens ocupa i es concep com una publicació periòdica en format revista que tracta el tema de les plantes, des de diferents àmbits. A través del Treball Final de Grau es desenvolupa i planteja el projecte en la seva globalitat: des de la conceptualització del magazine, la definició de la seva estructura, la recopilació i creació del material visual, fins al posterior disseny i maquetació d’un número prototip. Amb aquesta publicació es pretén impulsar uns coneixements bàsics, però molt útils, que despertin l’interès del lector.Mimosa nace de la combinación de dos pasiones de ámbitos muy distintos que gracias a este proyecto pueden confluir. Se trata de la fusión del mundo de las plantas y todo aquello que las envuelve, con el terreno editorial. La unión de las dos disciplinas han dado lugar al proyecto que nos ocupa y se concibe como una publicación periódica en formato revista que trata el tema de las plantas, des de distintos ámbitos. A través del Trabajo Final de Grado se desarrolla y se plantea un proyecto en su globalidad: des de la conceptualización magazine, la definición de su estructura, la recopilación y creación del material visual, hasta el posterior diseño y maquetación de un número prototipo. Con esta publicación se pretende impulsar unos conocimientos básicos, pero muy útiles, que despierten el interés del lector.Mimosa is born from the combination of two passions from very different worlds. Thanks to this project both passions meet. The project is about the fusion of the plant’s universe and everything around them, with the editorial world. The mix of both disciplines is introduced in a periodic publication that makes the project alive. The publication is a magazine that talks about plants, from different point of views. The Final Degree Project covers the development of an entire design process including: magazine conceptualization, structure defintion, visual material compilation, and creation as well as the final design, layout preparation, and prototyping. The publications aim to raise the reader’s interest by providing basic, but useful content

    4t Seminari sobre educació tecnològica

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    A new era for Advances in Laboratory Medicine

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    Journal Citation Reports; PubMed; Impact factorInformes de citas de revistas; PubMed; Factor de impactoInformes de cites de revistes; PubMed; Factor d'impact

    Intestinal Levodopa/Carbidopa Infusion as a Therapeutic Option for Unresponsive Freezing of Gait after Deep Brain Stimulation in Parkinson's Disease

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    Background. Treatment of freezing of gait (FOG) is always challenging because of its unpredictable nature and multifactorial physiopathology. Intestinal levodopa infusion has been proposed in recent years as a valuable option for its improvement. FOG in Parkinson's disease (PD) can appear after deep brain stimulation in patients who never had gait symptoms. Objective. To study the effects of intestinal levodopa/carbidopa infusion in unresponsive-FOG that appears in PD patients treated with subthalamic nucleus deep brain stimulation. Methods. We retrospectively collected and analyzed demographic, clinical, and therapeutic data from five PD patients treated with subthalamic nucleus stimulation who developed unresponsive-FOG and received intestinal levodopa/carbidopa infusion as an alternative therapy. FOG was measured based on scores in item 14 of the Unified Parkinson's Disease Rating Scale before and after intestinal levodopa infusion. Results. Administration of intestinal levodopa caused improvement of FOG in the "ON" state in four patients (80%) by 2 or more points in item 14 of the Unified Parkinson's Disease Rating Scale. The improvement was maintained for at least 12 months. Conclusions. Intestinal levodopa infusion may be a valuable therapeutic option for unresponsive-FOG developed after subthalamic nucleus deep brain stimulation

    Estimation of the number of Anisakis larvae in commercial fish using a descriptive model based on real-time PCR

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    BACKGROUND: Seafood parasitation by Anisakis (Anisakidae) larvae has been reported in most of the oceans and seas worldwide.The presence of these nematodes in commonly consumed fish represents a potential hazard for consumers as they can provoke gastrointestinal symptoms and allergic reactions. In the present work, the capacity of a SYBR Green qPCR protocol to quantify Anisakis larvae in commercial fish was evaluated using experimentally spiked samples with different numbers (0-50) of A. simplex third-stage larvae (L3). To verify the agreement of the obtained results, 25 naturally infected fish specimens of Atlantic blue whiting underwent a parallel visual inspection. RESULTS: The logarithmic behavior of the Cq data obtained from the experimentally spiked samples allowed the development of a descriptive mathematical model that correlates the Cq value with the number of Anisakis larvae (R2 = 0.9908, CV = 2.37%). In the commercial blue whiting specimens there was a high correlation between the results of the molecular technique and the visual inspection (R2 = 0.9912); the Bland-Altman analysis showed that 94% of the differences were within the limits of agreement (−4.98 and 6.68), indicating the reliability of the descriptive mathematical model based on the SYBR Green qPCR technique. CONCLUSION: The descriptive function presented based on the SYBR Green qPCR assay is promising as a sensitive and accurate tool for measuring the Anisakis larval load in commercial fish, with a potential application not only in the food industry but also in prevention programs for public health

    Rinitis crónica en tortugas terrestres mediterráneas

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    Se describen la sintomatología, alteraciones hematológicas y bioquímicas más importantes, junto con las lesiones histológicas que aparecen en la rinitis crónica de las tortugas terrestres mediterráneas

    Numerical simulation of heat transfer and fluid flow in a flat plate solar collector with TIM and ventilation channel

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    Flat plate solar collector with plastic transparent insulation materials and ventilation channel as overheating protection system inserted between the absorber and the back insulation has been studied numerically. First, a general object-oriented unsteady model of this solar collector is developed and presented. It allows solving, in parallel way, every component separately and interacting with its neighbors to set the boundary conditions in every time step of the simulation. Every component can be simulated using its own mesh and the number of CPUs necessary (depending on the simulation level needed). Second, the numerical simulations of the fluid flow and heat transfer by natural convection in the bottom part (ventilation channel) and the upper part (air gap + TIM) of the collector are done separately. The simulation has taken into account the different operation modes of the channel (opened at high operation temperatures and closed in normal operations). A three dimensional parallel turbulent CFD model based on Large Eddy Simulation is used in the simulations. The obtained numerical results are validated with experimental and benchmark results found in the literature.Peer ReviewedPostprint (published version
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