Resolution analysis of switching converter models for hardware-in-the-loop

Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. O. Goñi, A. Sánchez, E. Todorovich, Á. de Castro, "Resolution Analysis of Switching Converter Models for Hardware-in-the-Loop", IEEE Transactions on Industrial Informatics, vol. 10, no.2, pp.1162 - 1170, May, 2014This work proposes two methods to determine the resolution of state variables in models of switching-mode power converters. The target models are intended for hardware-in-the-loop, i.e., closed-loop emulation using a model of the power converter implemented in digital hardware with the controller in its final implementation. The focus here is on the resolution of fixed-point models, although the results can also be applied to the significand resolution in floating-point representation. The first method is based on the simulation, provides the designer with the optimum resolution values, and guarantees that using the resolution, the converter will behave as it was specified. The second method is fast but conservative, intended for applications without hard constraints of area and speed. Despite the simplicity of the second method, its results, although slightly overestimated, have been demonstrated to be correct by the results of the first method. A boost converter for the power factor correction is used as an application example. As the converter model is intended for field-programmable gate array implementation, its area and maximum clock frequency are also analyzed. In this application example, the results show that the area grows linearly with the number of bits of each state variable, and the clock frequency is dominated by the width of one of the variables.This work was partially supported by the Agencia Nacional de Promoción Científica y Tecnológica, Argentina, through Project PICT 2009 - 0041

The nanomechanics of neurotoxina proteins reveals common features at the start of the neurodegeneration cascade.

1 pags. -- 56th Annual Meeting of the Biophysical-Society, FEB 25-29, 2012, San Diego, CAAmyloidogenic neurodegenerative diseases are incurable conditions caused by specific largely disordered proteins. However, the underlying molecular mechanism remains elusive. A favored hypothesis postulates that a critical conformational change in the monomer (an ideal therapeutic target) in these ‘‘neurotoxic proteins’’ triggers the pathogenic cascade. Using force spectroscopy with unequivocal singlemolecule identification we demonstrate a rich conformational polymorphism at their monomer level. This polymorphism strongly correlates with amyloidogenesis and neurotoxicity: it is absent in a fibrillization-incompetent mutant, favored by familial-disease mutations and diminished by a surprisingly promiscuous inhibitor of the monomeric b-conformational change and neurodegeneration. The demonstrated ability to inhibit the conformational heterogeneity of these proteins by a single pharmacological agent reveals common features in the monomer and suggests a common pathway to diagnose, prevent, halt or reverse multiple neurodegenerative disease

Descripción del inventario multidimensional para los trastornos emocionales (MEDI) para la evaluación y diagnóstico dimensional

El modelo híbrido dimensional-categorial para el diagnóstico de los trastornos emocionales propone la existencia de un conjunto de dimensiones compartidas asociadas a la etiología y mantenimiento de los diferentes trastornos emocionales (trastornos de ansiedad, del estado de ánimo y otros trastornos relacionados). El Inventario Multidimensional para los Trastornos Emocionales (MEDI) se desarrolló para evaluar de manera eficiente las dimensiones propuestas por este modelo híbrido (neuroticismo, afecto positivo, estado de ánimo deprimido, activación autónoma, ansiedad somática, ansiedad social, intrusiones cognitivas, reexperimentación traumática y evitación) y cuenta con pruebas de validez en España. El objetivo del presente artículo es describir esta herramienta de evaluación dimensional y comparar sus resultados con los obtenidos siguiendo los criterios del DSM-5 en una serie de casos clínicos. Se discuten las virtudes del MEDI y las ventajas de una perspectiva dimensional transdiagnóstica en la personalización del tratamiento psicológico

Twitter as a Tool for Teaching and Communicating Microbiology: The #microMOOCSEM Initiative

Online social networks are increasingly used by the population on a daily basis. They are considered a powerful tool for science communication and their potential as educational tools is emerging. However, their usefulness in academic practice is still a matter of debate. Here, we present the results of our pioneering experience teaching a full Basic Microbiology course via Twitter (#microMOOCSEM), consisting of 28 lessons of 40-45 minutes duration each, at a tweet per minute rate during 10 weeks. Lessons were prepared by 30 different lecturers, covering most basic areas in Microbiology and some monographic topics of general interest (malaria, HIV, tuberculosis, etc.). Data analysis on the impact and acceptance of the course were largely affirmative, promoting a 330% enhancement in the followers and a >350-fold increase of the number of visits per month to the Twitter account of the host institution, the Spanish Society for Microbiology. Almost one third of the course followers were located overseas. Our study indicates that Massive Online Open Courses (MOOC) via Twitter are highly dynamic, interactive, and accessible to great audiences, providing a valuable tool for social learning and communicating science. This strategy attracts the interest of students towards particular topics in the field, efficiently complementing customary academic activities, especially in multidisciplinary areas like Microbiology.Versión del edito

Monografies del Montseny - 37

Antoni Pladevall Font va fer possible el naixement de la col.lecció completa de les Monografies del Montseny, n’ha estat el director durant molts anys, ha publicat més de seixanta treballs d’investigació històrica, i ha estat el mestre que ha mostrat el camí a seguir en la tasca d’aprofundiment de la història del Montseny i el seu entorn més proper. En el pròleg del volum 37 de les Monografies del Montseny es glosa la figura d’Antoni Pladevall Font, qui l’any 1966 inicià la col·laboració en el Servei de Conservació i Catalogació de Monuments Històrics a la Diputació de Barcelona; dos anys més tard, passà a exercir com a professor d’història medieval a la Facultat de Teologia de Barcelona. Obtingué el títol d’Arxiver Municipal de Vic l’any 1979, mentre treballa a la Diputació, i al 1981començà a treballar en el Departament de Cultura de la Generalitat fins a la seva jubilació l’any 1999. L’aleshores conseller de Cultura de la Generalitat Max Cahner li va encarregar d’organitzar el Servei de Conservació i Restauració de Monuments Arquitectònics on se li va assignar la secció d’inventari i la de cap de servei en funcions. Dos anys després hi va exercir com a director general del Patrimoni Arquitectònic. En aquesta etapa va col·laborar amb la Fundació i Editorial de la Gran Enciclopèdia Catalana, en la qual va exercir la direcció d’obres tan importants com la “Catalunya Romànica” i “L’Art Gòtic de Catalunya”, i va assessorar la “Gran Geografia Comarcal de Catalunya”.Objectius de Desenvolupament Sostenible::11 - Ciutats i Comunitats SosteniblesObjectius de Desenvolupament Sostenible::4 - Educació de QualitatPostprint (published version

Aislamiento, caracterización y funcionalidad de quitinasas y 1,3-β-glucanasas inducidas diferencialmente en frutos de "Annona cherimola" Mill por bajas temperaturas y elevadas concentraciones de CO2

El objetivo general de esta Tesis Doctoral es el estudio de la implicación de quitinasas y 1,3-β-glucanasas en la respuesta de defensa de chirimoya a bajas temperaturas de conservación (6 ºC) y en el mecanismo de tolerancia activado por el pretratamiento con 20 % de CO2

Endoquitinasa ácida activa a bajas temperaturas, procedimiento de obtención y usos

Endoquitinasa ácida activa a bajas temperaturas, procedimiento de obtención y usos. Endoquitinasa obtenida a partir de la pulpa de especies de la familia Annonaceae, catalíticamente activa a bajas temperaturas, con capacidad antifúngica y estable a pH ácido, procedimiento de obtención, y usos.Peer reviewedConsejo Superior de Investigaciones Científicas (España)A1 Solicitud de patentes con informe sobre el estado de la técnic