Helping Made Easy: Ease of Argument Generation Enhances Intentions to Help

Previous work has shown that self-generating arguments is more persuasive than reading arguments provided by others, particularly if self-generation feels easy. The present study replicates and extends these findings by providing evidence for fluency effects on behavioral intention in the realm of helping. In two studies, participants were instructed to either self-generate or read two versus ten arguments about why it is good to help. Subsequently, a confederate asked them for help. Results show that self-generating few arguments is more effective than generating many arguments. While this pattern reverses for reading arguments, easy self-generation is the most effective strategy compared to all other conditions. These results have important implications for fostering behavioral change in all areas of life

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

Heart failure is a leading cause of mortality, yet our understanding of the genetic interactions underlying this disease remains incomplete. Here, we harvest 1352 healthy and failing human hearts directly from transplant center operating rooms, and obtain genome-wide genotyping and gene expression measurements for a subset of 313. We build failing and non-failing cardiac regulatory gene networks, revealing important regulators and cardiac expression quantitative trait loci (eQTLs). PPP1R3A emerges as a regulator whose network connectivity changes significantly between health and disease. RNA sequencing after PPP1R3A knockdown validates network-based predictions, and highlights metabolic pathway regulation associated with increased cardiomyocyte size and perturbed respiratory metabolism. Mice lacking PPP1R3A are protected against pressure-overload heart failure. We present a global gene interaction map of the human heart failure transition, identify previously unreported cardiac eQTLs, and demonstrate the discovery potential of disease-specific networks through the description of PPP1R3A as a central regulator in heart failure

Plausible association of distant late M dwarfs with low-frequency radio emission

We present the serendipitous discovery of 8 distant ($>$ 50 pc) late M dwarfs with plausible associated radio emission at 144 MHz. The M dwarf nature of our sources has been confirmed with optical spectroscopy performed using HET/LRS2 and Subaru/FOCAS, and their radio flux densities are within the range of 0.5-1.0 mJy at 144 MHz. Considering the radio-optical source separation and source densities of the parent catalogues, we suggest that it is statistically probable the M dwarfs are associated with the radio emission. However, it remains plausible that for some of the sources the radio emission originates from an optically faint and red galaxy hiding behind the M dwarf. The isotropic radio luminosities ($\sim10^{17-18}$ erg s$^{-1}$ Hz$^{-1}$) of the M dwarfs suggest that if the association is real, the radio emission is likely driven by a coherent emission process produced via plasma or electron-cyclotron maser instability processes, which is potentially caused by binary interaction. Long term monitoring in the radio and high-resolution radio follow-up observations are necessary to search for any variability and pinpoint the radio emission to determine whether our tentative conclusion that these ultracool dwarfs are radio emitting is correct. If the low-frequency radio emission is conclusively associated with the M dwarfs, this would reveal a new population of optically faint and distant ($>$ 50 pc) radio emitting M dwarfs.Comment: 10 pages, 5 figures, accepted for publication in A&

Low frequency radio properties of the z > 5 quasar population

Optically luminous quasars at $z > 5$ are important probes of super-massive black hole (SMBH) formation. With new and future radio facilities, the discovery of the brightest low-frequency radio sources in this epoch would be an important new probe of cosmic reionization through 21-cm absorption experiments. In this work, we systematically study the low-frequency radio properties of a sample of 115 known spectroscopically confirmed $z>5$ quasars using the second data release of the Low Frequency Array (LOFAR) Two Metre Sky survey (LoTSS-DR2), reaching noise levels of $\sim$80 $\mu$Jy beam$^{-1}$ (at 144 MHz) over an area of $\sim5720$ deg$^2$. We find that 41 sources (36%) are detected in LoTSS-DR2 at $>2 \sigma$ significance and we explore the evolution of their radio properties (power, spectral index, and radio loudness) as a function of redshift and rest-frame ultra-violet properties. We obtain a median spectral index of $-0.29^{+0.10}_{-0.09}$ by stacking 93 quasars using LoTSS-DR2 and Faint Images of the Radio Sky at Twenty Centimetres (FIRST) data at 1.4 GHz, in line with observations of quasars at $z<3$. We compare the radio loudness of the high-$z$ quasar sample to a lower-$z$ quasar sample at $z\sim2$ and find that the two radio loudness distributions are consistent with no evolution, although the low number of high-z quasars means that we cannot rule out weak evolution. Furthermore, we make a first order empirical estimate of the $z=6$ quasar radio luminosity function, which is used to derive the expected number of high-$z$ sources that will be detected in the completed LoTSS survey. This work highlights the fact that new deep radio observations can be a valuable tool in selecting high-$z$ quasar candidates for follow-up spectroscopic observations by decreasing contamination of stellar dwarfs and reducing possible selection biases introduced by strict colour cuts.Comment: 11 pages, 10 figures, accepted for publication in A&

Comparisons between SCIAMACHY and ground-based FTIR data for total columns of CO, CH₄, CO₂ and N₂O

Total column amounts of CO, CH4, CO2 and N2O retrieved from SCIAMACHY nadir observations in ist near-infrared channels have been compared to data from a ground-based quasi-global network of Fourier-transform infrared (FTIR) spectrometers. The SCIAMACHY data considered here have been produced by three different retrieval algorithms, WFM-DOAS (version 0.5 for CO and CH4 and version 0.4 for CO2 and N2O), IMAP-DOAS (version 1.1 and 0.9 (for CO)) and IMLM (version 6.3) and cover the January to December 2003 time period. Comparisons have been made for individual data, as well as for monthly averages. To maximize the number of reliable coincidences that satisfy the temporal and spatial collocation criteria, the SCIAMACHY data have been compared with a temporal 3rd order polynomial interpolation of the ground-based data. Particular attention has been given to the question whether SCIAMACHY observes correctly the seasonal and latitudinal variability of the target species. The present results indicate that the individual SCIAMACHY data obtained with the actual versions of the algorithms have been significantly improved, but that the quality requirements, for estimating emissions on regional scales, are not yet met. Nevertheless, possible directions for further algorithm upgrades have been identified which should result in more reliable data products in a near future

Early anthropogenic CH4 emissions and the variation of CH4 and (CH4)-C-13 over the last millennium

This study presents a new hypothesis to explain the observed variation of C