Response of Marine‐Terminating Glaciers to Forcing: Time Scales, Sensitivities, Instabilities, and Stochastic Dynamics

Recent observations indicate that many marine‐terminating glaciers in Greenland and Antarctica are currently retreating and thinning, potentially due to long‐term trends in climate forcing. In this study, we describe a simple two‐stage model that accurately emulates the response to external forcing of marine‐terminating glaciers simulated in a spatially extended model. The simplicity of the model permits derivation of analytical expressions describing the marine‐terminating glacier response to forcing. We find that there are two time scales that characterize the stable glacier response to external forcing, a fast time scale of decades to centuries, and a slow time scale of millennia. These two time scales become unstable at different thresholds of bed slope, indicating that there are distinct slow and fast forms of the marine ice sheet instability. We derive simple expressions for the approximate magnitude and transient evolution of the stable glacier response to external forcing, which depend on the equilibrium glacier state and the strength of nonlinearity in forcing processes. The slow response rate of marine‐terminating glaciers indicates that current changes at some glaciers are set to continue and accelerate in coming centuries in response to past climate forcing and that the current extent of change at these glaciers is likely a small fraction of the future committed change caused by past climate forcing. Finally, we find that changing the amplitude of natural fluctuations in some nonlinear forcing processes, such as ice shelf calving, changes the equilibrium glacier state

The Mutual Interaction between Continental-Scale Ice Sheets and Atmospheric Stationary Waves

The great continental ice sheets of the Pleistocene represented significant obstacles to the Northern Hemisphere midlatitude westerlies. They must therefore have forced large changes in the atmospheric circulation, and con-sequently also in the patterns of accumulation and melting over the ice sheets themselves. A simplified three-dimensional coupled ice sheet–stationary wave model is developed in order to understand the ice sheet’s response to the circulation changes that it induces. Consistent with ice age climate simulations, the ice sheet topography induces an anticyclonic circulation over the ice sheet, causing a slight warming over the western slopes and a stronger cooling over the remainder. The modeled feedbacks significantly affect the ice sheet configuration, with the most important influences being the patterns of summer temperature, and the topographically induced pre-cipitation field. The time evolution of the ice sheet is also changed by the atmospheric feedbacks and the results suggest the possibility of multiple equilibrium solutions. 1

Response of Marine‐Terminating Glaciers to Forcing: Time Scales, Sensitivities, Instabilities, and Stochastic Dynamics

Recent observations indicate that many marine‐terminating glaciers in Greenland and Antarctica are currently retreating and thinning, potentially due to long‐term trends in climate forcing. In this study, we describe a simple two‐stage model that accurately emulates the response to external forcing of marine‐terminating glaciers simulated in a spatially extended model. The simplicity of the model permits derivation of analytical expressions describing the marine‐terminating glacier response to forcing. We find that there are two time scales that characterize the stable glacier response to external forcing, a fast time scale of decades to centuries, and a slow time scale of millennia. These two time scales become unstable at different thresholds of bed slope, indicating that there are distinct slow and fast forms of the marine ice sheet instability. We derive simple expressions for the approximate magnitude and transient evolution of the stable glacier response to external forcing, which depend on the equilibrium glacier state and the strength of nonlinearity in forcing processes. The slow response rate of marine‐terminating glaciers indicates that current changes at some glaciers are set to continue and accelerate in coming centuries in response to past climate forcing and that the current extent of change at these glaciers is likely a small fraction of the future committed change caused by past climate forcing. Finally, we find that changing the amplitude of natural fluctuations in some nonlinear forcing processes, such as ice shelf calving, changes the equilibrium glacier state

The remote impacts of climate feedbacks on regional climate predictability

Uncertainty in the spatial pattern of climate change is dominated by divergent predictions among climate models. Model differences are closely linked to their representation of climate feedbacks, that is, the additional radiative fluxes that are caused by changes in clouds, water vapour, surface albedo, and other factors, in response to an external climate forcing. Progress in constraining this uncertainty is therefore predicated on understanding how patterns of individual climate feedbacks aggregate into a regional and global climate response. Here we present a simple, moist energy balance model that combines regional feedbacks and the diffusion of both latent and sensible heat. Our model emulates the relationship between regional feedbacks and temperature response in more comprehensive climate models; the model can therefore be used to understand how uncertainty in feedback patterns drives uncertainty in the patterns of temperature response. We find that whereas uncertainty in tropical feedbacks induces a global response, the impact of uncertainty in polar feedbacks remains predominantly regionally confined

Predictive use of the Maximum Entropy Production principle for Past and Present Climates

In this paper, we show how the MEP hypothesis may be used to build simple climate models without representing explicitly the energy transport by the atmosphere. The purpose is twofold. First, we assess the performance of the MEP hypothesis by comparing a simple model with minimal input data to a complex, state-of-the-art General Circulation Model. Next, we show how to improve the realism of MEP climate models by including climate feedbacks, focusing on the case of the water-vapour feedback. We also discuss the dependence of the entropy production rate and predicted surface temperature on the resolution of the model

The growth of northeastern Tibet and its relevance to large-scale continental geodynamics: A review of recent studies

Recent studies of the northeastern part of the Tibetan Plateau have called attention to two emerging views of how the Tibetan Plateau has grown. First, deformation in northern Tibet began essentially at the time of collision with India, not 10–20 Myr later as might be expected if the locus of activity migrated northward as India penetrated the rest of Eurasia. Thus, the north-south dimensions of the Tibetan Plateau were set mainly by differences in lithospheric strength, with strong lithosphere beneath India and the Tarim and Qaidam basins steadily encroaching on one another as the region between them, the present-day Tibetan Plateau, deformed, and its north-south dimension became narrower. Second, abundant evidence calls for acceleration of deformation, including the formation of new faults, in northeastern Tibet since ~15 Ma and a less precisely dated change in orientation of crustal shortening since ~20 Ma. This reorientation of crustal shortening and roughly concurrent outward growth of high terrain, which swings from NNE-SSW in northern Tibet to more NE-SW and even ENE-WSW in the easternmost part of northeastern Tibet, are likely to be, in part, a consequence of crustal thickening within the high Tibetan Plateau reaching a limit, and the locus of continued shortening then migrating to the northeastern and eastern flanks. These changes in rates and orientation also could result from removal of some or all mantle lithosphere and increased gravitational potential energy per unit area and from a weakening of crustal material so that it could flow in response to pressure gradients set by evolving differences in elevation

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A genome-wide survival analysis of 14,406 Alzheimer's disease (AD) cases and 25,849 controls identified eight previously reported AD risk loci and 14 novel loci associated with age at onset. Linkage disequilibrium score regression of 220 cell types implicated the regulation of myeloid gene expression in AD risk. The minor allele of rs1057233 (G), within the previously reported CELF1 AD risk locus, showed association with delayed AD onset and lower expression of SPI1 in monocytes and macrophages. SPI1 encodes PU.1, a transcription factor critical for myeloid cell development and function. AD heritability was enriched within the PU.1 cistrome, implicating a myeloid PU.1 target gene network in AD. Finally, experimentally altered PU.1 levels affected the expression of mouse orthologs of many AD risk genes and the phagocytic activity of mouse microglial cells. Our results suggest that lower SPI1 expression reduces AD risk by regulating myeloid gene expression and cell function

Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability

Micromechanical Properties of Injection-Molded Starch–Wood Particle Composites

The micromechanical properties of injection molded starch–wood particle composites were investigated as a function of particle content and humidity conditions. The composite materials were characterized by scanning electron microscopy and X-ray diffraction methods. The microhardness of the composites was shown to increase notably with the concentration of the wood particles. In addition,creep behavior under the indenter and temperature dependence were evaluated in terms of the independent contribution of the starch matrix and the wood microparticles to the hardness value. The influence of drying time on the density and weight uptake of the injection-molded composites was highlighted. The results revealed the role of the mechanism of water evaporation, showing that the dependence of water uptake and temperature was greater for the starch–wood composites than for the pure starch sample. Experiments performed during the drying process at 70°C indicated that the wood in the starch composites did not prevent water loss from the samples.Peer reviewe