9,395 research outputs found
Exploring How Counselor Education Programs Support Site Supervisors
CACREP standards require counselor education programs to provide site supervisors with orientation, consultation, and professional development opportunities (PD). Using a nonexperimental descriptive design, we collected data from a national sample of CACREP-accredited programs (N=46, 13.3% response rate) via an online descriptive survey to explore how programs provide such opportunities to site supervisors. The survey contained open-ended and multiple-choice items addressing orientation, consultation, PD, and participants’ opinions on how their program addressed the three domains. We analyzed numerical data using descriptive statistics and open-ended responses using content analysis. We found that most programs offered orientation, consultation, and PD, though site supervisor engagement and methods of implementation varied considerably. Implications for research and practice are discussed in light of the findings
MPLA as an Innovative Immune Countermeasure
Spaceflight perturbs the human immune system. Among other manifestations, crewmembers may experience latent herpes viruses reactivation due to impaired lymphocyte function, as well as allergic/hypersensitivity reactions. Considering future space travel will be of longer duration (thereby increasing stress, exposure to radiation, etc) with no rapid return option, it is of paramount importance to develop a countermeasure(s) to immune dysregulation. Monophosphoryl lipid A (MPLA) is a derivative of lipopolysaccharide (LPS), a potent inflammatory agent that can cause septic shock. MPLA possesses the immune-stimulatory effects of LPS without the adverse inflammatory effects. We hypothesize that treating immune cells with MPLA will boost their function enough to overcome the inhibitory effects of microgravity. While MPLA has been tested as an adjuvant extensively in mice and preliminarily for human vaccines, it has never been assessed for efficacy in microgravity
The Nature of LINERs
We present -band (m) spectroscopy of a sample of nine
galaxies showing some degree of LINER activity (classical LINERs, weak-[O {\sc
i}] LINERs and transition objects), together with -band spectroscopy for
some of them. A careful subtraction of the stellar continuum allows us to
obtain reliable [Fe {\sc ii}]m/Pa line ratios. We conclude
that different types of LINERs (i.e., photoionized by a stellar continuum or by
an AGN) cannot be easily distinguished based solely on the [Fe {\sc ii}]m/Pa line ratio.
The emission line properties of many LINERs can be explained in terms of an
aging starburst. The optical line ratios of these LINERs are reproduced by a
model with a metal-rich H {\sc ii} region component photoionized with a single
stellar temperature K, plus a supernova remnant (SNR) component.
The [Fe {\sc ii}] line is predominantly excited by shocks produced by SNRs in
starbursts and starburst-dominated LINERs, while Pa tracks H {\sc ii}
regions ionized by massive young stars. The contribution from SNRs to the
overall emission line spectrum is constrained by the [Fe {\sc ii}]m/Pa line ratio. Although our models for aging starbursts are
constrained only by these infrared lines, they consistently explain the optical
spectra of the galaxies also.
The LINER-starburst connection is tested by predicting the time dependence of
the ratio of the ionizing luminosity () to the supernova rate
(SNr), /(SNr). We predict the relative number of starbursts to
starburst-dominated LINERs (aging starbursts) and show that it is in
approximate agreement with survey findings for nearby galaxies.Comment: Accepted in ApJ (19 pages, 8 figures, uses emulateapj.sty
Near-Infrared and Star-forming properties of Local Luminous Infrared Galaxies
We use HST NICMOS continuum and Pa-alpha observations to study the
near-infrared and star-formation properties of a representative sample of 30
local (d ~ 35-75Mpc) luminous infrared galaxies (LIRGs, infrared 8-1000um
luminosities of L_IR=11-11.9[Lsun]). The data provide spatial resolutions of
25-50pc and cover the central ~3.3-7.1kpc regions of these galaxies. About half
of the LIRGs show compact (~1-2kpc) Pa-alpha emission with a high surface
brightness in the form of nuclear emission, rings, and mini-spirals. The rest
of the sample show Pa-alpha emission along the disk and the spiral arms
extending over scales of 3-7kpc and larger. About half of the sample contains
HII regions with H-alpha luminosities significantly higher than those observed
in normal galaxies. There is a linear empirical relationship between the mid-IR
24um and hydrogen recombination (extinction-corrected Pa-alpha) luminosity for
these LIRGs, and the HII regions in the central part of M51. This relation
holds over more than four decades in luminosity suggesting that the mid-IR
emission is a good tracer of the star formation rate (SFR). Analogous to the
widely used relation between the SFR and total IR luminosity of Kennicutt
(1998), we derive an empirical calibration of the SFR in terms of the
monochromatic 24um luminosity that can be used for luminous, dusty galaxies.Comment: Accepted for publication in ApJ. Contact first author for high
qualitity version of figure
Cardiac troponin I release after a basketball match in elite, amateur and junior players
BACKGROUND:
Available scientific data related to cardiac troponin I (cTnI) release after intermittent exercise is limited. It is also of interest to determine what personal or environmental factors mediate the exercise-induced release of cTnI. This study had two objectives: 1) to examine the individual release of cTnI to a basketball match; and 2) to establish the influence of athlete status as well as biological age on cTnI release.
METHODS:
Thirty-six basketball players (12 adult elite [PBA]: 27.3±4.1 years, 12 adult amateur [ABA]: 29.6±2.9 years, and 12 junior elite [JBA]: 16.6±0.9 years) participated in a simulated basketball match with serial assessment of cTnI at rest, immediately post- and at 1, 3, 6, 12, and 24 h post-exercise.
RESULTS:
The basketball match increased cTnI levels (pre: median [range]; 0.006 [0.001-0.026]; peak post: 0.024 [0.004-0.244] μg/L; p=0.000), with substantial individual variability in peak values. PBA and JBA players showed higher baseline and post-exercise cTnI values than ABA (all p<0.05). Peak cTnI exceeded the upper reference limit (URL) in the 26% of players (3 PBA; 6 JBA).
CONCLUSIONS:
The current results suggest that intermittent exercise can promote the appearance of cTnI and that this is potentially mediated by athlete status
The Algorithm Steering and Trigger Decision mechanism of the ATLAS High Level Trigger
Given the extremely high output rate foreseen at LHC and the general-purpose
nature of ATLAS experiment, an efficient and flexible way to select events in
the High Level Trigger is needed. An extremely flexible solution is proposed
that allows for early rejection of unwanted events and an easily configurable
way to choose algorithms and to specify the criteria for trigger decisions. It
is implemented in the standard ATLAS object-oriented software framework,
Athena. The early rejection is achieved by breaking the decision process down
into sequential steps. The configuration of each step defines sequences of
algorithms which should be used to process the data, and 'trigger menus' that
define which physics signatures must be satisfied to continue on to the next
step, and ultimately to accept the event. A navigation system has been built on
top of the standard Athena transient store (StoreGate) to link the event data
together in a tree-like structure. This is fundamental to the seeding
mechanism, by which data from one step is presented to the next. The design
makes it straightforward to utilize existing off-line reconstruction data
classes and algorithms when they are suitableComment: Talk from the 2003 Computing in High Energy and Nuclear Physics
(CHEP03), La Jolla, Ca, USA, March 2003, 8 pages, PDF, PSN TUGT00
The Young Pulsar J1357-6429 and Its Pulsar Wind Nebula
We observed the young pulsar J1357--6429 with the {\it Chandra} and {\it
XMM-Newton} observatories. The pulsar spectrum fits well a combination of
absorbed power-law model () and blackbody model
( eV, km at the distance of 2.5 kpc). Strong
pulsations with pulsed fraction of , apparently associated with the
thermal component, were detected in 0.3--1.1 keV. Surprisingly, pulsed fraction
at higher energies, 1.1--10 keV, appears to be smaller, . The small
emitting area of the thermal component either corresponds to a hotter fraction
of the neutron star (NS) surface or indicates inapplicability of the simplistic
blackbody description. The X-ray images also reveal a pulsar-wind nebula (PWN)
with complex, asymmetric morphology comprised of a brighter, compact PWN
surrounded by the fainter, much more extended PWN whose spectral slopes are
and , respectively. The extended PWN with
the observed flux of erg s cm is a factor
of 10 more luminous then the compact PWN. The pulsar and its PWN are located
close to the center of the extended TeV source HESS J1356--645, which strongly
suggests that the VHE emission is powered by electrons injected by the pulsar
long ago. The X-ray to TeV flux ratio, , is similar to those of other
relic PWNe. We found no other viable candidates to power the TeV source. A
region of diffuse radio emission, offset from the pulsar toward the center of
the TeV source, could be synchrotron emission from the same relic PWN rather
than from the supernova remnant.Comment: 18 pages, 12 figures, and 4 tables, Accepted for publication in Ap
Active noise control over adaptive distributed networks
© 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/This paper presents the implementation of Active Noise Control (ANC) systems over a network of distributed acoustic nodes. For this purpose we define a general acoustic node consisting of one or several microphones and one or several loudspeakers together with a unique processor with communication capabilities. ANC systems can use a wide range of adaptive algorithms, but we have considered specifically the Multiple Error Filtered-x Least Mean Square (MEFxLMS), which has been proved to perform very well for ANC systems with multiple microphones and loudspeakers, and centralized processing. We present a new formulation to introduce the distributed version of the MEFxLMS together with an incremental collaborative strategy in the network. We demonstrate that the distributed MEFxLMS exhibits the same performance as the centralized one when there are no communication constraints in the network. Then, we re-formulate the distributed MEFxLMS to include parameters related to its implementation on an acoustic sensor network: latency of the network, computational capacity of the nodes, and trustworthiness of the signals measured at each node. Simulation results in realistic scenarios show the ability of the proposed distributed algorithms to achieve good performance when proper values of these parameters are chosen. (C) 2014 Elsevier B.V. All rights reserved.This work has been supported by European Union ERDF and Spanish Government through TEC2012-38142-C04 Project, and Generalitat Valenciana through PROMETEOII/2014/003 Project.Ferrer Contreras, M.; Diego Antón, MD.; Piñero Sipán, MG.; González Salvador, A. (2015). Active noise control over adaptive distributed networks. Signal Processing. 107:82-95. https://doi.org/10.1016/j.sigpro.2014.07.026S829510
Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference
Learned associations between environmental cues and morphine use play an important role in the maintenance and/or relapse of opioid addiction. Although previous studies suggest that context-dependent morphine treatment alters glutamatergic transmission and synaptic plasticity in the hippocampus, their role in morphine conditioned place preference (CPP) and reinstatement remains unknown. We investigated changes in synaptic plasticity and NMDAR expression in the hippocampus after the expression, extinction, and reinstatement of morphine CPP. Here we report that morphine CPP is associated with increased basal synaptic transmission, impaired hippocampal long-term potentiation (LTP), and increased synaptic expression of the NR1 and NR2b NMDAR subunits. Changes in synaptic plasticity, synaptic NR1 and NR2b expression, and morphine CPP were absent when morphine was not paired with a specific context. Furthermore, hippocampal LTP was impaired and synaptic NR2b expression was increased after extinction of morphine CPP, indicating that these alterations in plasticity may be involved in the mechanisms underlying the learning of drug–environment associations. After extinction of morphine CPP, a priming dose of morphine was sufficient to reinstate morphine CPP and was associated with LTP that was indistinguishable from saline control groups. In contrast, morphine CPP extinguished mice that received a saline priming dose did not show CPP and had disrupted hippocampal LTP. Finally, we found that reinstatement of morphine CPP was prevented by the selective blockade of the NR2b subunit in the hippocampus. Together, these data suggest that alterations in synaptic plasticity and glutamatergic transmission play an important role in the reinstatement of morphine CPP
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