15 research outputs found
Радіолокаційно-вихрострумовий метод виявлення металів
Сучасний георадар – це складний геофізичний прилад для неруйнівного контролю неоднорідностей середовища. В основі роботи георадару лежить підповерхневе зондуванняявище відбивання електромагнітної хвилі від межі поділу шарів з різною діелектричною чи магнітною проникністю. Такими межами є локальні неоднорідності різної природи. Георадари з великою вірогідністю визначають цю неоднорідність та глибину її залягання, але не можуть визначити склад неоднорідності, наприклад, це сталь чи золото. Тому виникла необхідність у створенні георадару без цього недоліку
Simulating the physiology of athletes during endurance sports events: modelling human energy conversion and metabolism
The human physiological system is stressed to its limits during endurance sports competition events. We describe a whole body computational model for energy conversion during bicycle racing. About 23 per cent of the metabolic energy is used for muscle work, the rest is converted to heat. We calculated heat transfer by conduction and blood flow inside the body, and heat transfer from the skin by radiation, convection and sweat evaporation, resulting in temperature changes in 25 body compartments. We simulated a mountain time trial to Alpe d'Huez during the Tour de France. To approach the time realized by Lance Armstrong in 2004, very high oxygen uptake must be sustained by the simulated cyclist. Temperature was predicted to reach 39°C in the brain, and 39.7°C in leg muscle. In addition to the macroscopic simulation, we analysed the buffering of bursts of high adenosine triphosphate hydrolysis by creatine kinase during cyclical muscle activity at the biochemical pathway level. To investigate the low oxygen to carbohydrate ratio for the brain, which takes up lactate during exercise, we calculated the flux distribution in cerebral energy metabolism. Computational modelling of the human body, describing heat exchange and energy metabolism, makes simulation of endurance sports events feasible
Global media as an early warning tool for food fraud; an assessment of MedISys-FF
Food fraud is a serious problem that may compromise the safety of the food products being sold on the market. Previous studies have shown that food fraud is associated with a large variety of food products and the fraud type may vary from deliberate changing of the food product (i.e. substitution, tampering, dilution etc.) to the manipulation of documents. It is therefore important that all actors within the food supply chain (food producers, authorities), have methodologies and tools available to detect fraudulent products at an early stage so that preventative measures can be taken. Several of such systems exist (i.e. iRASFF, EMA, HorizonScan, AAC-FF, MedISys-FF), but currently only MedISys-FF is publicly online available. In this study, we analyzed food fraud cases collected by MedISys-FF over a 6-year period (2015–2020) and show global trends and developments in food fraud activities. In the period investigated, the system has collected 4375 articles on food fraud incidents from 164 countries in 41 different languages. Fraud with meat and meat products were most frequently reported (27.7%), followed by milk and milk products (10.5%), cereal and bakery products (8.3%), and fish and fish products (7.7%). Most of the fraud was related to expiration date (58.3%) followed by tampering (22.2%) and mislabeling of country of origin (11.4%). Network analysis showed that the focus of the articles was on food products being frauded. The validity of MedISys-FF as an early warning system was demonstrated with COVID- 19. The system has collected articles discussing potential food fraud risks due to the COVID-19 crisis. We therefore conclude that MedISys-FF is a very useful tool to detect early trends in food fraud and may be used by all actors in the food system to ensure safe, healthy, and authentic food
Constraint-based probabilistic learning of metabolic pathways from tomato volatiles
Clustering and correlation analysis techniques have become popular tools for the analysis of data produced by metabolomics experiments. The results obtained from these approaches provide an overview of the interactions between objects of interest. Often in these experiments, one is more interested in information about the nature of these relationships, e.g., cause-effect relationships, than in the actual strength of the interactions. Finding such relationships is of crucial importance as most biological processes can only be understood in this way. Bayesian networks allow representation of these cause-effect relationships among variables of interest in terms of whether and how they influence each other given that a third, possibly empty, group of variables is known. This technique also allows the incorporation of prior knowledge as established from the literature or from biologists. The representation as a directed graph of these relationship is highly intuitive and helps to understand these processes. This paper describes how constraint-based Bayesian networks can be applied to metabolomics data and can be used to uncover the important pathways which play a significant role in the ripening of fresh tomatoes. We also show here how this methods of reconstructing pathways is intuitive and performs better than classical techniques. Methods for learning Bayesian network models are powerful tools for the analysis of data of the magnitude as generated by metabolomics experiments. It allows one to model cause-effect relationships and helps in understanding the underlying processes
QCD and strongly coupled gauge theories : challenges and perspectives
We highlight the progress, current status, and open challenges of QCD-driven physics, in theory and in experiment. We discuss how the strong interaction is intimately connected to a broad sweep of physical problems, in settings ranging from astrophysics and cosmology to strongly coupled, complex systems in particle and condensed-matter physics, as well as to searches for physics beyond the Standard Model. We also discuss how success in describing the strong interaction impacts other fields, and, in turn, how such subjects can impact studies of the strong interaction. In the course of the work we offer a perspective on the many research streams which flow into and out of QCD, as well as a vision for future developments.Peer reviewe
Artificial intelligence to detect unknown stimulants from scientific literature and media reports
The world market for food supplements is large and is driven by the claims of these products to, for example, treat obesity, increase focus and alertness, decrease appetite, decrease the need for sleep or reduce impulsivity. The use of illegal compounds in food supplements is a continuous threat, certainly because these compounds and products have not been tested for safety by competent authorities. It is therefore of the utmost importance for the competent authorities to know when new products are being marketed and to warn users against potential health risks. In this study, an approach is presented to detect new and unknown stimulants in food supplements using machine learning. Twenty new stimulants were identified from two different data sources, namely scientific literature applying word embedding on > 2 million abstracts and articles from formal and social media on the world wide web using text mining. The results show that the developed approach may be suitable to detect “unknowns” in the emerging risk identification activities performed by the competent authorities, which is currently a major hurdle
Automated plot of estimated fluxes in a model of brain energy metabolism.
<p>Automated plot of estimated fluxes in a model of brain energy metabolism.</p