Discovery of new globular clusters in the Sagittarius dwarf galaxy

© ESO 2021. Published by EDP Sciences. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1051/0004-6361/202140395Context. Globular clusters (GCs) are witnesses of the past accretion events onto the Milky Way. In particular, the GCs of the Sagittarius (Sgr) dwarf galaxy are important probes of an on-going merger. Aims. Our main goal is to search for new GC members of this dwarf galaxy using the VISTA Variables in the Via Lactea Extended Survey (VVVX) near-infrared database combined with the Gaia Early Data Release 3 (EDR3) optical database. Methods. We investigated all VVVX-enabled discoveries of GC candidates in a region covering about 180 sq. deg. toward the bulge and the Sgr dwarf galaxy. We used multiband point-spread function photometry to obtain deep color-magnitude diagrams (CMDs) and luminosity functions (LFs) for all GC candidates, complemented by accurate Gaia-EDR3 proper motions (PMs) to select Sgr members and variability information to select RR Lyrae which are potential GC members. Results. After applying a strict PM cut to discard foreground bulge and disk stars, the CMDs and LFs for some of the GC candidates exhibit well defined red giant branches and red clump giant star peaks. We selected the best Sgr GCs, estimating their distances, reddenings, and associated RR Lyrae. Conclusions. We discover 12 new Sgr GC members, more than doubling the number of GCs known in this dwarf galaxy. In addition, there are 11 other GC candidates identified that are uncertain, awaiting better data for confirmation.Peer reviewedFinal Accepted Versio

Adaptively Transforming Graph Matching

Recently, many graph matching methods that incorporate pairwise constraint and that can be formulated as a quadratic assignment problem (QAP) have been proposed. Although these methods demonstrate promising results for the graph matching problem, they have high complexity in space or time. In this paper, we introduce an adaptively transforming graph matching (ATGM) method from the perspective of functional representation. More precisely, under a transformation formulation, we aim to match two graphs by minimizing the discrepancy between the original graph and the transformed graph. With a linear representation map of the transformation, the pairwise edge attributes of graphs are explicitly represented by unary node attributes, which enables us to reduce the space and time complexity significantly. Due to an efficient Frank-Wolfe method-based optimization strategy, we can handle graphs with hundreds and thousands of nodes within an acceptable amount of time. Meanwhile, because transformation map can preserve graph structures, a domain adaptation-based strategy is proposed to remove the outliers. The experimental results demonstrate that our proposed method outperforms the state-of-the-art graph matching algorithms

Author correction : a global database for metacommunity ecology, integrating species, traits, environment and space

Correction to: Scientific Data https://doi.org/10.1038/s41597-019-0344-7, published online 08 January 202

Author correction : a global database for metacommunity ecology, integrating species, traits, environment and space

Correction to: Scientific Data https://doi.org/10.1038/s41597-019-0344-7, published online 08 January 202

Population-Level Metrics of Trophic Structure Based on Stable Isotopes and Their Application to Invasion Ecology

Biological invasions are a significant driver of human-induced global change and many ecosystems sustain sympatric invaders. Interactions occurring among these invaders have important implications for ecosystem structure and functioning, yet they are poorly understood. Here we apply newly developed metrics derived from stable isotope data to provide quantitative measures of trophic diversity within populations or species. We then use these to test the hypothesis that sympatric invaders belonging to the same functional feeding group occupy a smaller isotopic niche than their allopatric counterparts. Two introduced, globally important, benthic omnivores, Louisiana swamp crayfish (Procambarus clarkii) and carp (Cyprinus carpio), are sympatric in Lake Naivasha, Kenya. We applied our metrics to an 8-year data set encompassing the establishment of carp in the lake. We found a strong asymmetric interaction between the two invasive populations, as indicated by inverse correlations between carp abundance and measures of crayfish trophic diversity. Lack of isotopic niche overlap between carp and crayfish in the majority of years indicated a predominantly indirect interaction. We suggest that carp-induced habitat alteration reduced the diversity of crayfish prey, resulting in a reduction in the dietary niche of crayfish. Stable isotopes provide an integrated signal of diet over space and time, offering an appropriate scale for the study of population niches, but few isotope studies have retained the often insightful information revealed by variability among individuals in isotope values. Our population metrics incorporate such variation, are robust to the vagaries of sample size and are a useful additional tool to reveal subtle dietary interactions among species. Although we have demonstrated their applicability specifically using a detailed temporal dataset of species invasion in a lake, they have a wide array of potential ecological applications

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Objectives:We utilized the database of the Defining Antibiotic Levels in Intensive care unit patients (DALI) study to statistically compare the pharmacokinetic/pharmacodynamic and clinical outcomes between prolonged-infusion and intermittent-bolus dosing of piperacillin/tazobactam and meropenem in critically ill patients using inclusion criteria similar to those used in previous prospective studies.Methods: This was a post hoc analysis of a prospective, multicentre pharmacokinetic point-prevalence study (DALI), which recruited a large cohort of critically ill patients from 68 ICUs across 10 countries.Results: Of the 211 patients receiving piperacillin/tazobactam and meropenem in the DALI study, 182 met inclusion criteria. Overall, 89.0% (162/182) of patients achieved the most conservative target of 50% fT(> MIC) (time over which unbound or free drug concentration remains above the MIC). Decreasing creatinine clearance and the use of prolonged infusion significantly increased the PTA for most pharmacokinetic/pharmacodynamic targets. In the subgroup of patients who had respiratory infection, patients receiving beta-lactams via prolonged infusion demonstrated significantly better 30 day survival when compared with intermittent-bolus patients [86.2% (25/29) versus 56.7% (17/30); P=0.012]. Additionally, in patients with a SOFA score of >= 9, administration by prolonged infusion compared with intermittent-bolus dosing demonstrated significantly better clinical cure [73.3% (11/15) versus 35.0% (7/20); P=0.035] and survival rates [73.3% (11/15) versus 25.0% (5/20); P=0.025].Conclusions: Analysis of this large dataset has provided additional data on the niche benefits of administration of piperacillin/tazobactam and meropenem by prolonged infusion in critically ill patients, particularly for patients with respiratory infections