80 research outputs found
Composites based on natural fibres and thermoplastic matrices.
PhDThis thesis examines the possibility of reinforcing thermoplastic matrices, notably
polypropylene (PP) and polyhydroxyalkanoates (PHAs), by (a vegetable fibre) flax.
An effort is made to enhance/optimise the mechanical properties of flax, PP
composites through a micromechanical and macromechanical study. The fibrc'matrix
interface is modified via chemical modifications as well as modifications in
processing parameters (transcrystallinity).
Effects of parameters like fibre length, fibre volume fraction and fibre-matrix interface
modification on the mechanical properties of long flax fibre reinforced PP composites
(compression moulded) as well as short flax fibre based composites (injection
moulded) are studied. In order to get a better insight in the importance of these
different parameters for the optimisation of composite performance, the experimental
results are compared with model predictions using micromechanical models for
random short-fibre-reinforced composites. For the injection moulded composites,
different compounding routes are used and compared.
The moisture resistance (pick-up and diffusivity) as well as dimensional stability
(swelling) of natural fibre mat reinforced thermoplastics (NMTs), based on different
kinds of flax fibres and PPs, are studied. The effects of a novel fibre upgrading
method for flax fibres (DuralinTM) on the moisture pick-up and residual tensile
properties of NMT composites are explored.
Biodegradable composites based on flax fibre and PHAs are analysed. It is observed
that addition of (cheap) flax fibre to polyhydroxybutyrate (PHB) could be
advantageous as far as cost-performance of biopolymer composites is concerned.
especially for stiffness critical applications. Mechanical properties of `biocomposites'
manufactured through different routes (i. e. injection moulding and compression
moulding) are compared. Addition of cheap flax fibres to an expensive and brittle
PI IA composite leads to enhanced toughness of the composites.
Abstract
A life cycle assessment (LCA) study on glass-fibre-mat-reinforced-thermoplastic
(GMT) and NMT manufactured by a current production method for thermoplastic
prepregs followed by compression moulding into an automotive and non-automotive
part is carried out
Mechanical properties of natural-fibre-mat-reinforced thermoplastics based on flax fibres and polypropylene.
Thermoplastic composites based on flax fibres and a polypropylene (PP) matrix were manufactured using (i) a film-stacking method based on random fibre mats and (ii) a paper making process based on chopped fibres. The influence of fibre length and fibre content on stiffness, strength and impact strength of these so-called natural-fibre-mat-reinforced thermoplastics (NMTs) is reported and compared with data for glass-mat-reinforced thermoplastics (GMTs), including the influence of the use of maleic-anhydride grafted PP for improved interfacial adhesion. In addition some preliminary data on the influence of fibre diameter on composite stiffness and strength is reported. The data is compared with the existing micro-mechanical models for strength and stiffness. A good agreement was found between theory and experiment in case of stiffness whereas in the case of strength the experimental values fall well below the theoretical predictions. Results indicated that NMTs are of interest for low-cost engineering applications and can compete with commercial GMTs when a high stiffness per unit weight is desirable. Results also indicated that future research towards significant improvements in tensile and impact strength of these types of composites should focus on the optimisation of fibre strength rather than interfacial bond strength
Cone Beam Computed Tomographic Analysis Demonstrates a 94% Radiographic Success Rate in 783 Alveolar Bone Grafts
Naturally Compatible: Starch Acetate/Cellulosic Fiber Composites. I. Processing and Properties
Optimisation of macro-mechanical properties of flax-fibre-reinforced PP based composites through micro-mechanical studies
Optimisation of macro-mechanical properties of flax-fibre-reinforced PP based composites through micro-mechanical studies
Epigenetic and Genomic Hallmarks of PARP-Inhibitor Resistance in Ovarian Cancer Patients
BACKGROUND: Patients with advanced-stage epithelial ovarian cancer (EOC) receive treatment with a poly-ADP ribose-polymerase (PARP) inhibitor (PARPi) as maintenance therapy after surgery and chemotherapy. Unfortunately, many patients experience disease progression because of acquired therapy resistance. This study aims to characterize epigenetic and genomic changes in cell-free DNA (cfDNA) associated with PARPi resistance. MATERIALS AND METHODS: Blood was taken from 31 EOC patients receiving PARPi therapy before treatment and at disease progression during/after treatment. Resistance was defined as disease progression within 6 months after starting PARPi and was seen in fifteen patients, while sixteen patients responded for 6 to 42 months. Blood cfDNA was evaluated via Modified Fast Aneuploidy Screening Test-Sequencing System (mFast-SeqS to detect aneuploidy, via Methylated DNA Sequencing (MeD-seq) to find differentially methylated regions (DMRs), and via shallow whole-genome and -exome sequencing (shWGS, exome-seq) to define tumor fractions and mutational signatures. RESULTS: Aneuploid cfDNA was undetectable pre-treatment but observed in six patients post-treatment, in five resistant and one responding patient. Post-treatment ichorCNA analyses demonstrated in shWGS and exome-seq higher median tumor fractions in resistant (7% and 9%) than in sensitive patients (7% and 5%). SigMiner analyses detected predominantly mutational signatures linked to mismatch repair and chemotherapy. DeSeq2 analyses of MeD-seq data revealed three methylation signatures and more tumor-specific DMRs in resistant than in responding patients in both pre- and post-treatment samples (274 vs. 30 DMRs, 190 vs. 57 DMRs, Χ2-test p < 0.001). CONCLUSION: Our genome-wide Next-Generation Sequencing (NGS) analyses in PARPi-resistant patients identified epigenetic differences in blood before treatment, whereas genomic alterations were more frequently observed after progression. The epigenetic differences at baseline are especially interesting for further exploration as putative predictive biomarkers for PARPi resistance.</p
Preparation and characterization of compression-molded green composite sheets made of poly(3-hydroxybutyrate) reinforced with long pita fibers
[EN] Novel green composites were successfully prepared from bacterial poly(3-hydroxybutyrate) (PHB) and pita fibers derived from the agave plant (Agave americana). Various weight contents (10, 20, 30, and 40 wt.-%) of pita fibers at different lengths (5, 15, and 20 mm) were successfully incorporated into PHB by compression molding. The newly prepared PHB/pita fibers composite sheets were characterized in terms of their mechanical and thermomechanical properties and then related to their morphology after fracture. Attained results indicated that the mechanical stiffness of PHB significantly improved with both the content and length of pita fibers, although ductile properties were reduced. In particular, the elastic modulus of the 40 wt.-% PHB composite sheets containing 20-mm-long pita fibers was approximately 55% higher than the unfilled PHB sheet. Shore D hardness also improved, achieving the shortest pita fibers the highest improvement. Pita fibers with lengths of 15 and 20 mm also increased the Vicat softening point and heat deflection temperature (HDT) by 38 and 21°C, respectively. Due to their optimal shape, it is concluded that pita fibers with lengths above 15 mm can potentially reinforce and improve the performance of PHB biopolymer. In addition, the compression-molding methodology described in this research work represents a cost-effective pathway to feasibly prepare long-fiber- reinforced thermoplastics (LFRTs) fully based on renewable raw materials. Resultant green composite sheets can be of interest for the development of sustainable parts in the automotive industry and other advanced applications in polymer technology.This research was supported by the Spanish Ministry of Economy and Competitiveness (project MAT2014-59242- C2-1-R). The authors also thank “Conselleria d’Educació, Cultura i Esport—Generalitat Valenciana” (grant number GV/2014/008) for financial support.Torres-Giner, S.; Montanes, N.; Fombuena, V.; Boronat, T.; Sanchez-Nacher, L. (2016). Preparation and characterization of compression-molded green composite sheets made of poly(3-hydroxybutyrate) reinforced with long pita fibers. Advances in Polymer Technology. 1-11. https://doi.org/10.1002/adv.21789S11
Particles of Coffee Wastes as Reinforcement in Polyhydroxybutyrate (PHB) Based Composites
- …