294 research outputs found
Unveiling thermal transitions of polymers in subnanometre pores
- Author
- A Bansal
- A Schönhals
- C Alba-Simionesco
- CJ Ellison
- CL Jackson
- CL Soles
- D Bradshaw
- D Frenkel
- G Dosseh
- G Férey
- GB DeMaggio
- GS Sur
- H Chun
- H Matsuura
- H Sakaguchi
- HD Rowland
- J Spevacek
- J-Y Park
- JH Kim
- K Dalnoki-Veress
- K Seki
- K Shin
- L Lafferentz
- M Alcoutlabi
- MG Martin
- MV Giotto
- OM Yaghi
- P Rittigstein
- PG de Gennes
- R Kitaura
- R Radhakrishnan
- R Tabeta
- RA Vaia
- S Horike
- S Kitagawa
- S Takamizawa
- S Watanabe
- T Ozawa
- T Uemura
- T Uemura
- T Uemura
- T Uemura
- V Crupi
- VM Egorov
- Y Deng
- Y Takahashi
- Publication venue
- Nature Publishing Group
- Publication date
- 01/01/2010
- Field of study
The thermal transitions of confined polymers are important for the application of polymers in molecular scale devices and advanced nanotechnology. However, thermal transitions of ultrathin polymer assemblies confined in subnanometre spaces are poorly understood. In this study, we show that incorporation of polyethylene glycol (PEG) into nanochannels of porous coordination polymers (PCPs) enabled observation of thermal transitions of the chain assemblies by differential scanning calorimetry. The pore size and surface functionality of PCPs can be tailored to study the transition behaviour of confined polymers. The transition temperature of PEG in PCPs was determined by manipulating the pore size and the pore–polymer interactions. It is also striking that the transition temperature of the confined PEG decreased as the molecular weight of PEG increased
The effect of reinforcement volume ratio on porosity and thermal conductivity in Al-Mgo composites
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Rearrangement of Retinogeniculate Projection Patterns after Eye-Specific Segregation in Mice
- Author
- AA Penn
- AD Huberman
- AD Huberman
- AD Huberman
- AD Huberman
- AL Upton
- AL Williams
- BE Reese
- BM Hooks
- C Pfeiffenberger
- CA Leamey
- CA Leamey
- CJ Akerman
- CJ Shatz
- DA Feldheim
- DC Linden
- DW Sretavan
- EA Lachica
- F Fujiyama
- G Jeffery
- G Muir-Robinson
- GL Lyford
- GS Huh
- H Kawasaki
- H Kawasaki
- Hiroshi Kawasaki
- Itaru Hayakawa
- J Demas
- J Toldi
- JA Gordon
- JA Robson
- JA Robson
- JE Coleman
- JL Hanover
- JM Conner
- JO Hahm
- JO Hahm
- KS Cramer
- KS Cramer
- KS Cramer
- L Iwai
- L Jaubert-Miazza
- LC Katz
- M Caleo
- M Majdan
- M Sur
- M Yoshida
- MB Feller
- MP Stryker
- Olivier Jacques Manzoni
- P Godement
- P Godement
- PW Land
- R Ogawa-Meguro
- RD Lund
- RD Lund
- RT Fremeau Jr
- RW Guillery
- T Toda
- TD Albright
- TK Hensch
- TL Hickey
- W Guido
- WB Cafferty
- Y Fukuda
- Y Mimura
- Y Tagawa
- Publication venue
- Public Library of Science
- Publication date
- 08/06/2010
- Field of study
It has been of interest whether and when the rearrangement of neuronal circuits can be induced after projection patterns are formed during development. Earlier studies using cats reported that the rearrangement of retinogeniculate projections could be induced even after eye-specific segregation has occurred, but detailed and quantitative characterization of this rearrangement has been lacking. Here we delineate the structural changes of retinogeniculate projections in the C57BL/6 mouse in response to monocular enucleation (ME) after eye-specific segregation. When ME was performed after eye-specific segregation, rearrangement of retinogeniculate axons in the dorsal lateral geniculate nucleus (dLGN) was observed within 5 days. Although this rearrangement was observed both along the dorsomedial-ventrolateral and outer-inner axes in the dLGN, it occurred more rapidly along the outer-inner axis. We also examined the critical period for this rearrangement and found that the rearrangement became almost absent by the beginning of the critical period for ocular dominance plasticity in the primary visual cortex. Taken together, our findings serve as a framework for the assessment of phenotypes of genetically altered mouse strains as well as provide insights into the mechanisms underlying the rearrangement of retinogeniculate projections
Zbtb20 modulates the sequential generation of neuronal layers in developing cortex
- Author
- A Faedo
- A Mallamaci
- A Zembrzycki
- Anastassia Stoykova
- Anton B. Tonchev
- C Hanashima
- C Lowther
- C Mitchelmore
- C Zhou
- C Zimmer
- DD O’Leary
- E Seuntjens
- EA Alcamo
- EH Rosenthal
- Eva H. Rosenthal
- GD Frantz
- GE Elsen
- GS Tomassy
- H Ino
- H Naka
- H Wang
- JB Angevine Jr
- JL Rubenstein
- JV Nielsen
- JV Nielsen
- JV Nielsen
- K Srinivasan
- KF Kelly
- KY Kwan
- KY Kwan
- L Conti
- M Gotz
- M Nagao
- M Nieto
- M Sur
- MB Rasmussen
- MH Dominguez
- Michèle Studer
- ML Vuillaume
- O Britanova
- P Arlotta
- P Rakic
- PS Joshi
- Q Liu
- R Salas
- RF Hevner
- RJ McEvilly
- RS Nowakowski
- S Bulchand
- S Muhlfriedel
- SJ Franco
- SK McConnell
- T Hisaoka
- T Kumamoto
- T Neuman
- T Takahashi
- TC Tuoc
- Tran Cong Tuoc
- V Cordeddu
- V Tarabykin
- W Zhang
- WL McKenna
- Y Nakagawa
- Y Qiu
- Y Sugitani
- Z Xie
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Inhibition of the Progesterone Nuclear Receptor during the Bone Linear Growth Phase Increases Peak Bone Mass in Female Mice
- Author
- A Razmara
- Aaron Pham
- B Gellersen
- B Grosse
- BA Cromer
- BA Scheven
- BP Halloran
- C Stirone
- CA Frye
- CC Johnston Jr
- CK Welt
- D Courteix
- DB Petitti
- DJ Rickard
- DM de Kretser
- DM de Kretser
- DN Kalu
- DS Perrien
- DS Reddy
- EC Hsiao
- EC Ward
- EI Barengolts
- EI Barengolts
- EL Greer
- EL Greer
- F Grassi
- F Lengyel
- G Azizi
- GS Martin
- H Huang
- Haiyan Chen
- HG Burger
- HJ Rohe
- J Iqbal
- JC Gallagher
- JC Prior
- JD Wang
- JE Brouwers
- JE Sanchez-Criado
- JE Sanchez-Criado
- JH Liu
- JJ Brosens
- JJ Cao
- JL Turgeon
- JM Pensler
- Jose A. L. Calbet
- JP Bonjour
- JP Lydon
- JS Schneider
- JS Schneider
- KA Ward
- L Chen
- LI Plotkin
- LK Bachrach
- LL Wei
- M Horowitz
- M Liang
- M Marzia
- M Matsumoto
- M Peacock
- M Takano
- MA Essers
- MC Slootweg
- Min Guan
- Mohammad Shahnazari
- N Danilovich
- N Sudoh
- Nancy E. Lane
- NE Lane
- NE Lane
- OM Conneely
- P Li
- P Mac Namara
- P MacNamara
- P Sur
- PE Chappell
- PE Chappell
- PM Crofton
- QP Wang
- S Labied
- SA Krum
- SC Manolagas
- SC Roemer
- T Abe
- T Cundy
- T Cundy
- T Cundy
- T Cundy
- T Meehan
- V Boonyaratanakornkit
- V Boonyaratanakornkit
- V Boonyaratanakornkit
- V Le Mellay
- V Matkovic
- VL Ferguson
- W Abplanalp
- W Fan
- W Yao
- W Yao
- W Yao
- Wei Yao
- Weiwei Dai
- Y Ishida
- Y Ishida
- Y Ishida
- Zhiqiang Chen
- Publication venue
- Public Library of Science
- Publication date
- 01/07/2010
- Field of study
Augmentation of the peak bone mass (PBM) may be one of the most effective interventions to reduce the risk of developing osteoporosis later in life; however treatments to augment PBM are currently limited. Our study evaluated whether a greater PBM could be achieved either in the progesterone nuclear receptor knockout mice (PRKO) or by using a nuclear progesterone receptor (nPR) antagonist, RU486 in mice. Compared to their wild type (WT) littermates the female PRKO mice developed significantly higher cancellous and cortical mass in the distal femurs, and this was associated with increased bone formation. The high bone mass phenotype was partially reproduced by administering RU486 in female WT mice from 1–3 months of age. Our results suggest that the inhibition of the nPR during the rapid bone growth period (1–3 months) increases osteogenesis, which results in acquisition of higher bone mass. Our findings suggest a crucial role for progesterone signaling in bone acquisition and inhibition of the nPR as a novel approach to augment bone mass, which may have the potential to reduce the burden of osteoporosis
Rationale and design for the Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease (PACE) study
- Author
- A Algra
- A Covic
- A Cupisti
- A Cupisti
- A Yildiz
- AC Armstrong
- AJ Bleyer
- AK Cheung
- AW Haider
- B Dursun
- BD Schreiber
- Bernard G Jaar
- BG Jaar
- CA Herzog
- CA Herzog
- D Green
- D Kromhout
- D Rubinger
- DK Hathaway
- E Paoletti
- E Yetkin
- F Floccari
- F Galetta
- FH Messerli
- FX Roithinger
- GA Block
- Gordon F Tomaselli
- GS Kamath
- H Bazett
- H Calkins
- H Fukuta
- H Fukuta
- H Ichikawa
- Heart rate variability
- HI Feldman
- HJ Crijns
- HL Greene
- I Girgis
- I Karayaylali
- I Lorincz
- JA Karnik
- JE Madias
- JJ Goldberger
- JL Houghton
- Joao A Lima
- JP Lash
- JR Hunt
- K Tamura
- K Tamura
- L Fei
- L Wexler
- Larisa G Tereshchenko
- LG Tereshchenko
- LP Fried
- LS Fridericia
- LS Gettes
- Lucy A Meoni
- M Baumert
- M Giordano
- M Howse
- M Johansson
- M Malik
- M Naghavi
- MA Morales
- MH Crawford
- Michelle M Estrella
- MJ Davies
- MK Shamseddin
- ML Marcus
- NG Kutner
- P Chang-Sing
- P Meier
- PC Nalos
- PH Pun
- PM Elliott
- R Fathi
- RN Foley
- RN Foley
- RN Foley
- RR Townsend
- RS Parekh
- Rulan S Parekh
- S Ahnve
- S Maule
- S Sur
- SM Singh
- ST Morris
- Stephen M Sozio
- T Kinoshita
- Tariq Shafi
- USRDS
- W H Linda Kao
- ZJ Zheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Cancer Biomarker Discovery: The Entropic Hallmark
- Author
- A Alcaraz
- A Arabzadeh
- A Bagri
- A Balbin
- A Bantis
- A Ben-Naim
- A Bolander
- A Buhmeida
- A Burykin
- A Chetcuti
- A de Baey
- A Efeyan
- A Eroglu
- A Fabarius
- A Forget
- A Fujita
- A Geirsson
- A Geirsson
- A Geirsson
- A Guffanti
- A Hugel
- A Inoue
- A Isidoro
- A Jang
- A Kollara
- A Kuzmanov
- A Lundqvist
- A Maria McCrohan
- A Marreiros
- A Mendes
- A Mitra
- A Nassar
- A Petitjean
- A Petitjean
- A Pinzon-Charry
- A Richmond
- A Roesch
- A Santinelli
- A Schmidt
- A Shapiro
- A Sreekumar
- A Takeno
- A Urbanucci
- A Winter
- A Yemelyanov
- AA Babiker
- AA Babiker
- AA Tarhini
- AC Dudley
- AD Judge
- AD Ortega
- AG Puebla-Mora
- AH Fox
- AH Fox
- AI Riker
- AJ Liu
- AK Meeker
- AK Panigrahi
- AK Witkiewicz
- AL Cheung
- AL Fachin
- AL Gartel
- AL Okorokov
- AM Craig
- AM Lena
- AM Levin
- AM Tokes
- AP South
- AS Payne
- AS Verkman
- AS Verkman
- AS Verkman
- AS Wierzbicki
- AV Skamrov
- AW Maniccia
- B Cinar
- B Gao
- B Ouyang
- B Ren
- B Ryu
- B Tycko
- B Vukovic
- B Wu
- B Wu
- BD Dimitrov
- BF Gilmore
- BF Goncalves
- BF Skinnider
- BK Zehentner
- BL Adamsen
- BL de Groot
- BR Johnson
- BR Middleman
- BS Strauss
- C Adami
- C Bastide
- C Cao
- C Cybulski
- C Haqq
- C Hayashi
- C Hornig
- C Ivorra
- C Kumar-Sinha
- C Langner
- C Magi-Galluzzi
- C Magi-Galluzzi
- C Muller-Tidow
- C Nessler-Menardi
- C Nunez
- C Pequeux
- C Rajesh
- C Xu
- C Yuli
- CD Sturgis
- CD Truong
- CG Pham
- CG Rogers
- CG Rogers
- CJ Hutchison
- CJ Pronk
- CK Mavis
- CL Stewart
- CL Wu
- CM Caves
- CM Caves
- CM Clemson
- CM Perou
- CP Gray
- CP Gray
- CP Gray
- CR Mangahas
- CS Bond
- D Acehan
- D Bonn
- D Denhardt
- D Fu
- D Gilley
- D Gisselsson
- D Hanahan
- D Javelaud
- D Kroepfl
- D Lodygin
- D Maraldo
- D Ouazia
- D Scadden
- D Wang
- D Wang
- D Wang
- D Weckermann
- D Wodarz
- DA Shoskes
- DA Tennant
- DE Hansel
- DF Gleason
- DG Albertson
- DG Tenen
- DH Palmer
- DJ Darley
- DJ Grignon
- DJ Smit
- DJ Son
- DJ Wong
- DJC MacKay
- DK Koynova
- DK Lee
- DM Kube
- DM Peehl
- DR Wonsey
- DS Perez
- DV Makarov
- DV Makarov
- E Beitz
- E Beitz
- E Cabuy
- E Fagiani
- E Flannery
- E Geissinger
- E Kikuchi
- E Kruse
- E Sbisa
- E Sprecher
- E Tajkhorshid
- EA Ostrander
- EH Feng
- EH Feng
- EM Rosen
- EM Rosen
- EM Schaeffer
- EO Kehinde
- ET Canepa
- EV Vykhovanets
- EY Lin
- EY Tan
- F Bai
- F Bonetto
- F Boralevi
- F Buback
- F Colotta
- F Langer
- F Saad
- F Tas
- F Yang
- FS Krause
- G Benga
- G Bhanot
- G Blandino
- G Buchanan
- G Kaic
- G Kristiansen
- G Kristiansen
- G Kroemer
- G Murugaiyan
- G Petrovics
- G Pirtskhalaishvili
- G Russo
- G Sardana
- G Stirling
- G Tscheudschilsuren
- G Untergasser
- G Venkataraman
- G von Figura
- GA Jarvis
- GE Crooks
- GF Azzone
- GF Ding
- GL Shen-Ong
- GP Bienert
- GQ Daley
- GR Ribeiro
- GS Palapattu
- GV Glinsky
- GV Glinsky
- H Chang-zheng
- H Chen
- H Dzojic
- H Gronberg
- H Haghnegahdar
- H Harant
- H Harlin
- H Kida
- H Li
- H Liu
- H Miyake
- H Nemoto
- H Ostrer
- H Pilch
- H Rangaswami
- H Rangaswami
- H Rangaswami
- H Ren
- H Roca
- H Roca
- H Samaratunga
- H Savli
- H Schlechte
- H Schoder
- H Sheng
- H Sunwoo
- H Then
- H Wang
- H Wang
- HC Lee
- HG Thomas
- HJ Worman
- HL Winfield
- HS Leff
- HT Quan
- HY Vu
- HZ Zhang
- I Agalliu
- I Bae
- I Ben-Porath
- I Grosse
- I Haritoglou
- I Leav
- I Marinescu
- I Moll
- I Sakai
- IE Wertz
- IK Lim
- IL Tourkova
- IM Bachmann
- IM Shih
- IW Reiniger
- IY Dodin
- J Bartkova
- J Edwards
- J Fellenberg
- J Gille
- J Graells
- J Jaeger
- J Johnson
- J Lammerding
- J Laoukili
- J Lapointe
- J Linden
- J Luo
- J Luo
- J Luo
- J Mandelin
- J Melamed
- J Moser
- J Rangel
- J Rapley
- J Reimand
- J Ruiz-Ederra
- J Schmitz
- J Schultz
- J Soikkeli
- J Stewart
- J Suh
- J Walter-Yohrling
- J Wang
- J Wang
- J Weiske
- J Xu
- J Yang
- J Yang
- J Zheng
- JA Camargo
- JA Douglas
- JA Hackett
- JA Karam
- JA McGrath
- JA McGrath
- JA McGrath
- JA McGrath
- JA Mobley
- JA Pettus
- JB Roche
- JC Cheville
- JD French
- JD Licchesi
- JD Owen
- JE Lai-Cheong
- JE Sleeman
- JE Wilusz
- JG Wen
- JH Lee
- JH Luo
- JJ Brey
- JJ Park
- JJ Raffoul
- JJ Tseng
- JJ Van den Oord
- JK Wahl 3rd
- JL Broers
- JL Herrmann
- JL Phillips
- JM Brandner
- JM Bridger
- JM Cummins
- JM Gonzalez
- JM Lizcano
- JM Muller
- JM Muller
- JM Parrondo
- JM Saffin
- JN Hutchinson
- JN Mubiru
- JN Mubiru
- JN Mubiru
- JP Arbitrario
- JP Clark
- JP Ehlers
- JP Fruehauf
- JP Struewing
- JR Cansino Alcaide
- JR McMillan
- JS Butler
- JS Butler
- JS Fang
- JS Hub
- JS Lee
- JS Mattick
- JS Mattick
- JS Mattick
- JT Bishoff
- JT Chang
- JW Denham
- K Armstrong
- K Fujita
- K Ishibashi
- K Ishitani
- K Kami
- K Kasuno
- K Kumagai
- K Mizutani
- K Namiki
- K Ruan
- K Ruan
- K Shilo
- K Sircar
- K Suzuki
- K Swisshelm
- K Takahara
- K Tani
- K Tokunaga
- K Tomkova
- K Trpkov
- K Yamada
- KA Tasken
- KA Zuhlke
- KH Hoffmann
- KH Tsui
- KL Nastiuk
- KL Simpson
- KL van Golen
- KN Ekdahl
- KP Porkka
- KR Ghani
- KV Prasanth
- L Capparuccia
- L Carlsson
- L Cheng
- L de Meis
- L Galluzzi
- L Kneisel
- L Lessard
- L Li
- L Moro
- L Moro
- L O'Regan
- L Packer
- L Pasini
- L True
- L Verdoucq
- L Verschooten
- L Xu
- L Zheng
- LA Diaz-Martinez
- LB Mora
- LE Clarke
- LE Finlan
- LF Brown
- LF Zerbini
- LL Chen
- LL Smith
- LL Smith
- LM Godsel
- LP Kunju
- M Aalamian-Matheis
- M Aghaei
- M Bakhanashvili
- M Boury-Jamot
- M Boury-Jamot
- M Buxade
- M Chellaiah
- M Cimitan
- M Craig
- M Dumas
- M Dundr
- M Esteller
- M Estler
- M Fabbri
- M Fukunaga-Kalabis
- M Fukunaga-Kalabis
- M Furuno
- M Gilbert
- M Hara-Chikuma
- M Hara-Chikuma
- M Hara-Chikuma
- M Hara-Chikuma
- M Hatzfeld
- M Hatzfeld
- M Heenen
- M Ismail
- M Karaivanov
- M Kashani-Sabet
- M Kato
- M Katoh
- M Kinoshita
- M Korabiowska
- M Kulesz-Martin
- M Lei
- M Lisovsky
- M Marko
- M Mellado
- M Mishima
- M Mockenhaupt
- M Moghaddami
- M Moghaddami
- M Nessling
- M Olsson
- M Onaitis
- M Parisi
- M Schostak
- M Tischkowitz
- M Traka
- M Tribus
- M Varma
- M Venoux
- M Watanabe
- M Yang
- M Yasui
- M Zhou
- M Zhou
- M Zhou
- MA Castro
- MA Chekmareva
- MA Chellaiah
- MA Ficazzola
- MA Halsey
- MA Roder
- MA Rubin
- MA Rubin
- MA Rubin
- MB Martens
- MB Rettig
- MC Caino
- MC Schumacher
- MD Desrosiers
- MD Duff
- MD Lloyd
- ME Blank
- ME Grossmann
- ME Grossmann
- ME Laski
- ME Morrison
- MF Fraga
- MH Vaarala
- MK Thomsen
- MK Thomsen
- MM Petrovic
- MM Rashid
- MR Rosner
- MS O'Connor
- MS Tretiakova
- MT Kalcioglu
- MT Ling
- MT Martin
- MT Sung
- MV Blagosklonny
- MY Lee
- N Bahamontes-Rosa
- N Donin
- N Konishi
- N Lapteva
- N Maeda
- N Nadiminty
- N Rabiau
- N Singh
- NG Hussein
- NI Andreyev
- NJ Fisch
- NV Whittock
- NV Whittock
- O Bettendorf
- O Canbolat
- O Itzhaki
- O Kwon
- OA Rosso
- OW Rokhlin
- P Agre
- P Agre
- P Agre
- P Agre
- P Allavena
- P Berthon
- P Boukamp
- P Cossu-Rocca
- P Dhawan
- P Dhawan
- P Duesberg
- P Duesberg
- P Duesberg
- P Hainaut
- P Ji
- P Karakiewicz
- P Koivisto
- P Roy-Burman
- P Rustin
- P Sini
- P Slijepcevic
- P Sotomayor
- P Sotomayor
- P Steigemann
- P Zhang
- Pablo Moscato
- PD Walden
- PG Gallagher
- PH Gumerlock
- PH Konig
- PI Nedvetsky
- PJ Gray Jr
- PJ Zielie
- PL Chang
- PM Lacal
- PM Lacal
- PM Mordaka
- PM Steijlen
- PT Landsberg
- PT Went
- PU Malmstrom
- PW Kuchel
- PW Lamberti
- Q Lu
- Q Zhou
- R Agarwal
- R Berretta
- R Birnie
- R Bordoni
- R Casalini
- R Das
- R Dobson
- R Halaban
- R Horuk
- R Klimek
- R Klimek
- R Kuefer
- R Lin
- R Mazzucchelli
- R Mukherjee
- R Radosavljevic
- R Rai
- R Sougrat
- RA Craven
- RA Hegele
- RA Sturm
- RA Weinberg
- RC Lee
- RD Ballal
- RD Loberg
- RD Loberg
- RD Loberg
- RD Loberg
- Regina Berretta
- RG Uzzo
- RJ Jin
- RJ Urban
- RJ Webster
- RL Boguslavsky
- RL Shattuck
- RMH Lopez-Ruiz
- RP Ciavarra
- RP Ciavarra
- RP Singh
- RS Weinstein
- RT Nitta
- RW DeVere White
- S Ashida
- S Brychtova
- S Cardinale
- S Das
- S Das
- S Dettwiler
- S Di Cesare
- S Doratiotto
- S Ersoy-Evans
- S Fan
- S Gagos
- S Ghosh
- S Gunia
- S Hanada
- S Hauptmann
- S Hiratsuka
- S Horsburgh
- S Huerta-Yepez
- S Jhavar
- S Jhavar
- S Kuwahara
- S Kyle
- S Landreville
- S Makovets
- S Morohashi
- S Olgac
- S Philip
- S Philip
- S Prislei
- S Rankin
- S Rankin
- S Satoh
- S Sur
- S Takahashi
- S Takahashi
- S Tancharoen
- S Verdier-Sevrain
- S Yeh
- S Zha
- S Zha
- S Zha
- SA Narod
- SH Lin
- SJ Yeung
- SK Kang
- SL Kong
- SL Zheng
- SM Edwards
- SM Ho
- SM Saparov
- SQ Xie
- SR Alonso
- SS Kadkol
- SV Setzer
- T Dalmay
- T Drewa
- T Hoevel
- T Ishiyama
- T Jamaspishvili
- T Kusumi
- T Litman
- T Ma
- T Mirtti
- T Murakami
- T Oyama
- T Schlomm
- T Schlomm
- T Sheridan
- T Shimizu
- T Sobolik-Delmaire
- T Sun
- T Takahashi
- T Takeda
- T Thornburg
- T Watanabe
- T Yu
- TB Lewis
- TD Prickett
- TH Ecke
- TJ McDonnell
- TJ Park
- TL Schmit
- TL Schmit
- TO Nielsen
- TR Mercer
- U Brinck
- U Graeven
- U Gruneberg
- UV Wesley
- V Ambros
- V Barak
- V Fradet
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Pekovic
- V Rajaram
- V Samanna
- V Wessagowit
- V Winnepenninckx
- VD Acevedo
- VK Vanguri
- VL Verstraeten
- W Chen
- W Cosme-Blanco
- W Gade
- W Ritchie
- W Spirkl
- W Tettelbach
- W Wang
- W Weichert
- W Weichert
- W Weichert
- WB Isaacs
- WD Dunsmuir
- WE Naugler
- William C. S. Cho
- WK Kaufmann
- WK Lee
- X Chen
- X Cheng
- X Dong
- X Dong
- X Huang
- X Li
- X Liu
- X Liu
- X Meng
- X Ouyang
- X Tang
- X Wu
- X Zhang
- XJ Yang
- XQ Wang
- Y Bu
- Y Cai
- Y Deng
- Y Ito
- Y Katagiri
- Y Kozuka
- Y Lai
- Y Liu
- Y Lu
- Y Lu
- Y Ohyama
- Y Shav-Tal
- Y Sugiyama
- Y Sun
- Y Wang
- Y Wang
- Y Wu
- Y Yamamoto
- Y Yang
- Y Zhou
- YB Lim
- YC Chao
- YJ Ko
- YL Liu
- YN Liu
- YT Sasaki
- YT Sasaki
- YU Katagiri
- Z Jiang
- Z Jiang
- Z Jiang
- Z Jiang
- Z Jiang
- Z Rudzki
- ZA Dotan
- ZR Yurkovetsky
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Background: It is a commonly accepted belief that cancer cells modify their transcriptional state during the progression of the disease. We propose that the progression of cancer cells towards malignant phenotypes can be efficiently tracked using high-throughput technologies that follow the gradual changes observed in the gene expression profiles by employing Shannon's mathematical theory of communication. Methods based on Information Theory can then quantify the divergence of cancer cells' transcriptional profiles from those of normally appearing cells of the originating tissues. The relevance of the proposed methods can be evaluated using microarray datasets available in the public domain but the method is in principle applicable to other high-throughput methods. Methodology/Principal Findings: Using melanoma and prostate cancer datasets we illustrate how it is possible to employ Shannon Entropy and the Jensen-Shannon divergence to trace the transcriptional changes progression of the disease. We establish how the variations of these two measures correlate with established biomarkers of cancer progression. The Information Theory measures allow us to identify novel biomarkers for both progressive and relatively more sudden transcriptional changes leading to malignant phenotypes. At the same time, the methodology was able to validate a large number of genes and processes that seem to be implicated in the progression of melanoma and prostate cancer. Conclusions/Significance: We thus present a quantitative guiding rule, a new unifying hallmark of cancer: the cancer cell's transcriptome changes lead to measurable observed transitions of Normalized Shannon Entropy values (as measured by high-throughput technologies). At the same time, tumor cells increment their divergence from the normal tissue profile increasing their disorder via creation of states that we might not directly measure. This unifying hallmark allows, via the the Jensen-Shannon divergence, to identify the arrow of time of the processes from the gene expression profiles, and helps to map the phenotypical and molecular hallmarks of specific cancer subtypes. The deep mathematical basis of the approach allows us to suggest that this principle is, hopefully, of general applicability for other diseases
The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali A
- Ab Khan M
- Abbas Q
- Abbasi B
- Abbasi-Kangevari M
- Abbasi-Kangevari Z
- Abbastabar H
- Abd-Elsalam S
- Abdelmasseh M
- Abdelwahab AA
- Abdoli G
- Abdulkader RS
- Abdulkadir HA
- AbdulmuhsinMohammad K
- Abedi A
- Abegaz KH
- Abidi H
- Aboagye RG
- Abolhassani H
- Absalan A
- Abtew YD
- Abu-Gharbieh E
- Achappa B
- Acheson AR
- Acuna JM
- Addison D
- Addo IY
- Adegboye OA
- Adesina MA
- Adnan M
- Adnani QES
- Advani SM
- Afrin S
- Afzal MS
- Aggarwal M
- Ahinkorah BO
- Ahmad AR
- Ahmad R
- Ahmad S
- Ahmadi S
- Ahmed H
- Ahmed LA
- Ahmed MB
- Aiman W
- Ajami M
- Akalu GT
- Akbarzadeh-Khiavi M
- Aklilu A
- Akonde M
- Akunna CJ
- Al Hamad H
- Al Montasir A
- Al-Hanawi MK
- Al-Maweri SAA
- Al-Raddadi RM
- Al-Rifai RHH
- Al-Sabah SK
- Al-Tammemi AB
- Alahdab F
- Alanezi FM
- Alanzi TM
- Alessy SA
- Algammal AM
- Alhassan RK
- Ali AH
- Ali BA
- Ali HA
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- Alipour V
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- Zeineddine MA
- Zhang D
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhou L
- Zodpey S
- Zoladl M
- Publication venue
- Publication date
- 20/08/2022
- Field of study
Search for strongly interacting massive particles generating trackless jets in proton-proton collisions at s = 13 TeV
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abercrombie D
- Acharya H
- Acosta D
- Acosta JG
- Adam W
- Adams E
- Adams MR
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- Adzic P
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- Agarwal G
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- Aguilar-Benitez M
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- Alcaraz Maestre J
- Aldaya Martin M
- Aldá Júnior WL
- Aleksandrov A
- Alexander J
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- Alimena J
- Alison J
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- Atanassov I
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- CMS Collaboration<sup>†</sup>
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- Vartak A
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- Wickramarathna DDC
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- Wulz C-E
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- Xia F
- Xiao J
- Xiao M
- Xiao R
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- Xie W
- Yagil A
- Yalvac M
- Yan F
- Yang UK
- Yang YC
- Yao Y
- Yarar H
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- Yazgan E
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- Yumiceva F
- Yusli MN
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- Zarubin A
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- Zecchinelli AG
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- Zeuner WD
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- Zorbilmez C
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- Álvarez Fernández A
- Österberg K
- Özçelik Ö
- Široký J
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
A search for dark matter in the form of strongly interacting massive particles (SIMPs) using the CMS detector at the LHC is presented. The SIMPs would be produced in pairs that manifest themselves as pairs of jets without tracks. The energy fraction of jets carried by charged particles is used as a key discriminator to suppress efficiently the large multijet background, and the remaining background is estimated directly from data. The search is performed using proton-proton collision data corresponding to an integrated luminosity of 16.1 fb - 1 , collected with the CMS detector in 2016. No significant excess of events is observed above the expected background. For the simplified dark matter model under consideration, SIMPs with masses up to 100 GeV are excluded and further sensitivity is explored towards higher masses
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
- Author
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- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
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- Zhemchugov A
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- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
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